September, 2024

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Presidential Candidates Should Undergo Standardized Cognitive and Physical Testing

Med Page Today

(MedPage Today) -- Health professionals often perform the "eyeball test" when they first meet a patient. Through the power of observation, pixels of information are gathered quickly and often unconsciously to determine whether a patient is unwell.

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Better cardiovascular health in early pregnancy may offset high genetic risk

American Heart News - Heart News

Research Highlights: Favorable cardiovascular health in early pregnancy, as measured by the American Heart Association's Life's Essential 8 (LE8) cardiovascular health score, was linked to lower risk of preeclampsia and gestational hypertension,

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The molecular landscape of vascular cells in the human brain

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 20 September 2024; doi:10.1038/s41569-024-01079-x A study using advanced single-cell technologies has broadened our understanding of the diversity and complexity of brain endothelial cells by uncovering new endothelial subtypes and transcriptional patterns. These findings offer insights into potential therapeutic targets and emphasize the need for further research on vascular lineages and neurovascular interactions.

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ESC 2024 Highlights

Cardiology Update

Dr. Chadi Alraies discusses some of the important trials presented at the European Society of Cardiology 2024 congress. Read more about the important ESC 2024 highlights. For more cardiology research news join our newsletter or follow us on Twitter , Facebook , LinkedIn or Instagram. The post ESC 2024 Highlights appeared first on Cardiology Update.

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Metals in the body from pollutants associated with progression of harmful plaque buildup in the arteries

Medical Xpress - Cardiology

Metal exposure from environmental pollution is associated with increased buildup of calcium in the coronary arteries at a level that is comparable to traditional risk factors like smoking and diabetes, according to a study by Columbia University Mailman School of Public Health.

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Effects of dietary interventions and intermittent fasting on HDL function in obese individuals with T2DM: a randomized controlled trial

Cardiovascular Diabetology

Cardiovascular disease represents a significant risk factor for mortality in individuals with type 2 diabetes mellitus (T2DM). High-density lipoprotein (HDL) is believed to play a crucial role in maintaining c.

Obesity 130
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Direct-to-Consumer Drugs: Big Pharma's Digital Health Play

Med Page Today

(MedPage Today) -- More than a quarter of a century ago, the FDA eased regulations to make it easier for pharmaceutical companies to advertise directly to consumers. Today, it is nearly impossible to get through a family sitcom without hearing.

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The gut microbiota in thrombosis

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 17 September 2024; doi:10.1038/s41569-024-01070-6 The gut microbiota has emerged as a risk factor that affects thrombotic phenotypes in several cardiovascular diseases. In this Review, Reinhardt and colleagues discuss the link between the gut microbiota, its metabolites and thromboembolic diseases, and summarize potential therapeutic interventions to modulate the gut microbiota.

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FDA Approves Dupilumab (Dupixent) for Treatment of COPD

HCPLive

This approval by the FDA follows positive findings from the pivotal BOREAS and NOTUS trials on adults with uncontrolled COPD.

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20 hospitals with highest, lowest heart failure death rates

Becker's Hospital Review - Cardiology

Chicago-based Northwestern Memorial Hospital and VA Boston Healthcare System-Jamaica Plain (Mass.) have the lowest death rate for heart failure patients in the country, according to CMS data.

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Babies born to women consuming a high fat, sugary diet at greater risk of cardiovascular disease and diabetes in later life

Science Daily - Heart Disease

Babies born to pregnant women with obesity are more likely to develop heart problems and diabetes as adults due to fetal damage caused by the high-fat, high-energy diet of their mother.

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Sexual and Gender Minorities More Likely to Have Adverse Brain Outcomes

Med Page Today

(MedPage Today) -- People who identified as a sexual or gender minority (LGBTQ+) had a higher likelihood of adverse brain health outcomes, cross-sectional data showed. Among nearly 400,000 participants in the All of Us research program, sexual.

Outcomes 131
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Happy with your life? Research links contentment with fewer heart attacks and strokes

American Heart News - Heart News

Research Highlights: People who are satisfied with their lives or feel contentment or well-being may be less likely to develop heart disease and stroke than their unsatisfied counterparts. The analysis of health records for more than 120,000 adults.

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Wearable heart monitor increases diagnosis of irregular heart rhythm

Science Daily - Stroke

Wearable, long-term continuous heart monitors helped identify 52% more cases of atrial fibrillation compared to usual care, but that did not lead to a reduction in hospitalizations due to stroke, according to a new study.

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Acute artery occlusion -- which one?

Dr. Smith's ECG Blog

Written by Willy Frick with edits by Ken Grauer A woman in her 70s with a history of hypertension presented with acute onset shortness of breath. She was out walking her dog when she developed sudden dizziness and light-headedness. When EMS found her, she was dyspneic and diaphoretic. Her ECG is shown below: What do you think? The conventional machine algorithm interpreted this ECG as STEMI.

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ECG Blog #448 — A Young Man with Chest Pain.

Ken Grauer, MD

The ECG in Figure-1 was obtained from a previously healthy man in his early 20s — who initially presented with GI symptoms, that then evolved into CP ( C hest P ain ). The patient was thought to have anxiety. QUESTIONS: Given the above history — How would YOU interpret the initial ECG that is shown in Figure-1 ? Does the patient's age infuence your interpretation?

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GLP-1R–positive neurons in the lateral septum mediate the anorectic and weight-lowering effects of liraglutide in mice

Journal of Clinical Investigation - Cardiology

Liraglutide, a glucagon-like peptide-1 (GLP-1) analog, is approved for obesity treatment, but the specific neuronal sites that contribute to its therapeutic effects remain elusive. Here, we show that GLP-1 receptor–positive (GLP-1R–positive) neurons in the lateral septum (LSGLP-1R) play a critical role in mediating the anorectic and weight-loss effects of liraglutide.

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Falling May Be a Harbinger of Dementia in Older Adults

Med Page Today

(MedPage Today) -- A new diagnosis of Alzheimer's disease or related dementia was more common after falls than after other traumatic injuries, an analysis of Medicare claims data showed. The study assessed nearly 2.5 million older adults who had.

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Remote monitoring and pharmacist helped improve hard-to-control blood pressure

American Heart News - Heart News

Research Highlights: A new study finds that up to 74% of participants with resistant or difficult-to-control high blood pressure, including those with chronic kidney disease, were able to improve control of their blood pressure within 12 months after.

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Frequent fizzy or fruit drinks and high coffee consumption linked to higher stroke risk

Science Daily - Stroke

Frequent drinking of fizzy drinks or fruit juice is associated with an increased risk of stroke, according to new findings. The research also found that drinking more than four cups of coffee per day also increases the risk of stroke.

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Dynamic OMI ECG. Negative trops and negative angiogram does not rule out coronary ischemia or ACS.

Dr. Smith's ECG Blog

By Smith, peer-reviewed by Interventional Cardiologist Emre Aslanger Submitted by anonymous A 53 y.o. male presents to the ED at 6:45 AM with left sided chest dull pressure that woke him up from sleep at 3am. The pain radiated to both shoulders. He arrived to the ED at around 6:45am, and stated the pain has persisted. He has had similar pain in recent weeks that has occurred at rest, but it typically goes away after about an hour.

Ischemia 121
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How many people have A-Fib? Three times more than we thought

Science Daily - Heart Disease

Atrial fibrillation, a rapid, irregular heart beat that can lead to stroke or sudden death, is three times more common than previously thought, affecting nearly 5% of the population, or 10.5 million U.S. adults, according to new estimates.

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NKT cells promote Th1 immune bias to dengue virus that governs long-term protective antibody dynamics

Journal of Clinical Investigation - Cardiology

NKT cells are innate-like T cells, recruited to the skin during viral infection, yet their contributions to long-term immune memory to viruses are unclear. We identified granzyme K, a product made by cytotoxic cells including NKT cells, as linked to induction of Th1-associated antibodies during primary dengue virus (DENV) infection in humans. We examined the role of NKT cells in vivo using DENV-infected mice lacking CD1d-dependent (CD1ddep) NKT cells.

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Up to 1 in 5 Dementia Cases May Be Attributable to Vision Impairment

Med Page Today

(MedPage Today) -- Up to one in five prevalent dementia cases may be attributable to impaired vision, a cross-sectional analysis suggested. In a study of nearly 2,800 older Americans, the population attributable fraction (PAF) of prevalent dementia.

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Measure of body roundness may help to predict risk of cardiovascular disease

American Heart News - Heart News

Research Highlights: Body roundness index — a measure to reflect abdominal body fat and height that some health care professionals believe better reflects the proportion of body fat and visceral fat than body mass index — may help to predict a.

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Higher Cardiovascular Health Reduced Risk of Gout

HCPLive

Higher Life’s Essential 8 score was associated with higher CVH scores in US adults.

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Acute chest pain, right bundle branch block, no STEMI criteria, and negative initial troponin.

Dr. Smith's ECG Blog

Written by Pendell Meyers A man in his 40s called EMS for acute chest pain that awoke him from sleep, along with nausea and shortness of breath. His history included known heart failure with prior EF 18%, insulin dependent diabetes, and polysubstance abuse. Vitals were within normal limits except for tachypnea. Here are his EMS ECGs along with the Queen of Hearts interpretations below each one: EMS1 0650 EMS2 0707 Click here to sign up for Queen of Hearts Access The ECGs show RBBB and LAFB, with

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The heart of the question: Who can get Medicare-covered weight loss medicine?

Science Daily - Heart Disease

With Medicare now covering semaglutide for people with obesity and cardiovascular disease who don't have diabetes, a study looks at who that might include, depending on what cutoffs prescription plans apply.

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Physiology Friday #237: An Evolutionary Perspective on Why Exercise Promotes Longevity

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. This week, I’m sharing one of my favorite articles I’ve ever written. I published it a few years ago, but since then have gained quite a few new subscribers. If you’re new, I hope you enjoy it for the first time. If you’re a long-time reader, I hope you re-enjoy it! I’ll be back next week with the usual coverage of a brand-new study.

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Study Finds More Heart Defects in Kids Conceived With ART

Med Page Today

(MedPage Today) -- Kids born via assisted reproductive technology (ART) had higher risk of congenital heart defects (CHDs), though the absolute risk difference was small, an observational Nordic study of 7.7 million children found. Major CHDs.

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High blood pressure a concern for adolescents and young adults in U.S.

American Heart News - Heart News

Research Highlights: In the first study, nearly 23% of young adults (ages 18-39 years) included in the NHANES 2017-2020 datasets had high blood pressure (130/80 mm Hg or greater). In addition, they were more likely to self-report being uninsured, food.

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FDA Approves Travere Therapuetics’ Sparsentan for Proteinuria Reduction in Adult Primary IgAN

HCPLive

The FDA has granted full approval to sparsentan (Filspari) for reducing proteinuria in adults with IgAN at risk of rapid disease progression based on PROTECT trial data.

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An elderly male with shortness of breath

Dr. Smith's ECG Blog

A 70-something y.o. male presents to triage with shortness of breath. He reports significant chest pain at the base of his scapula on the right side along with new shortness of breath. ECG 1 at time zero EARLY REPOLARIZATION ABNORMAL ECG ED final official overread: "early repol vs hyperacute T, minimal changes from previous (previous shown below)" What do YOU think?

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Breakthrough is a game changer in heart valve technology

Science Daily - Heart Disease

When a patient needs a new heart valve, the current mechanical and tissue replacements each have strengths and weaknesses. Now, a team of researchers believe they have found a way to harness the strengths of both technologies in a way that could be life-changing -- and life-saving -- for many.

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Soil and water pollution and cardiovascular disease

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 25 September 2024; doi:10.1038/s41569-024-01068-0 In this Review, Münzel and colleagues describe the adverse effects of soil and water pollution, including heavy metal, pesticide, and microplastic and nanoplastic pollution, on cardiovascular health and provide an overview of the eco-disruptive causes of this pollution.

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Metal Exposure Also Linked to More Coronary Artery Calcium

Med Page Today

(MedPage Today) -- Exposure to metals, essential or not, was associated with the progression of subclinical atherosclerosis, according to longitudinal data from a geographically diverse cohort. Study participants with the highest urinary metal.

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Are you one of the “Top Grateful Patients” at your hospital?

Heart Sisters

After my book was published, the hospital that had sent me home in mid-heart attack with an acid reflux misdiagnosis invited me to be the guest speaker at a fundraising campaign they were about to launch.

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