September, 2024

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Presidential Candidates Should Undergo Standardized Cognitive and Physical Testing

Med Page Today

(MedPage Today) -- Health professionals often perform the "eyeball test" when they first meet a patient. Through the power of observation, pixels of information are gathered quickly and often unconsciously to determine whether a patient is unwell.

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Better cardiovascular health in early pregnancy may offset high genetic risk

American Heart News - Heart News

Research Highlights: Favorable cardiovascular health in early pregnancy, as measured by the American Heart Association's Life's Essential 8 (LE8) cardiovascular health score, was linked to lower risk of preeclampsia and gestational hypertension,

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Metals in the body from pollutants associated with progression of harmful plaque buildup in the arteries

Medical Xpress - Cardiology

Metal exposure from environmental pollution is associated with increased buildup of calcium in the coronary arteries at a level that is comparable to traditional risk factors like smoking and diabetes, according to a study by Columbia University Mailman School of Public Health.

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ESC 2024 Highlights

Cardiology Update

Dr. Chadi Alraies discusses some of the important trials presented at the European Society of Cardiology 2024 congress. Read more about the important ESC 2024 highlights. For more cardiology research news join our newsletter or follow us on Twitter , Facebook , LinkedIn or Instagram. The post ESC 2024 Highlights appeared first on Cardiology Update.

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FDA Approves Dupilumab (Dupixent) for Treatment of COPD

HCPLive

This approval by the FDA follows positive findings from the pivotal BOREAS and NOTUS trials on adults with uncontrolled COPD.

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Frequent fizzy or fruit drinks and high coffee consumption linked to higher stroke risk

Science Daily - Stroke

Frequent drinking of fizzy drinks or fruit juice is associated with an increased risk of stroke, according to new findings. The research also found that drinking more than four cups of coffee per day also increases the risk of stroke.

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Direct-to-Consumer Drugs: Big Pharma's Digital Health Play

Med Page Today

(MedPage Today) -- More than a quarter of a century ago, the FDA eased regulations to make it easier for pharmaceutical companies to advertise directly to consumers. Today, it is nearly impossible to get through a family sitcom without hearing.

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A transparent AI approach helps provide a more tailored cardiovascular risk assessment

Medical Xpress - Cardiology

Risk calculators are used to evaluate disease risk for millions of patients, making their accuracy crucial. But when national models are adapted for local populations, they often deteriorate, losing accuracy and interpretability.

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20 hospitals with highest, lowest heart failure death rates

Becker's Hospital Review - Cardiology

Chicago-based Northwestern Memorial Hospital and VA Boston Healthcare System-Jamaica Plain (Mass.) have the lowest death rate for heart failure patients in the country, according to CMS data.

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Dynamic OMI ECG. Negative trops and negative angiogram does not rule out coronary ischemia or ACS.

Dr. Smith's ECG Blog

By Smith, peer-reviewed by Interventional Cardiologist Emre Aslanger Submitted by anonymous A 53 y.o. male presents to the ED at 6:45 AM with left sided chest dull pressure that woke him up from sleep at 3am. The pain radiated to both shoulders. He arrived to the ED at around 6:45am, and stated the pain has persisted. He has had similar pain in recent weeks that has occurred at rest, but it typically goes away after about an hour.

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The gut microbiota in thrombosis

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 17 September 2024; doi:10.1038/s41569-024-01070-6 The gut microbiota has emerged as a risk factor that affects thrombotic phenotypes in several cardiovascular diseases. In this Review, Reinhardt and colleagues discuss the link between the gut microbiota, its metabolites and thromboembolic diseases, and summarize potential therapeutic interventions to modulate the gut microbiota.

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Sexual and Gender Minorities More Likely to Have Adverse Brain Outcomes

Med Page Today

(MedPage Today) -- People who identified as a sexual or gender minority (LGBTQ+) had a higher likelihood of adverse brain health outcomes, cross-sectional data showed. Among nearly 400,000 participants in the All of Us research program, sexual.

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Remote monitoring and pharmacist helped improve hard-to-control blood pressure

American Heart News - Heart News

Research Highlights: A new study finds that up to 74% of participants with resistant or difficult-to-control high blood pressure, including those with chronic kidney disease, were able to improve control of their blood pressure within 12 months after.

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GLP-1R–positive neurons in the lateral septum mediate the anorectic and weight-lowering effects of liraglutide in mice

Journal of Clinical Investigation - Cardiology

Liraglutide, a glucagon-like peptide-1 (GLP-1) analog, is approved for obesity treatment, but the specific neuronal sites that contribute to its therapeutic effects remain elusive. Here, we show that GLP-1 receptor–positive (GLP-1R–positive) neurons in the lateral septum (LSGLP-1R) play a critical role in mediating the anorectic and weight-loss effects of liraglutide.

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ECG Blog #448 — A Young Man with Chest Pain.

Ken Grauer, MD

The ECG in Figure-1 was obtained from a previously healthy man in his early 20s — who initially presented with GI symptoms, that then evolved into CP ( C hest P ain ). The patient was thought to have anxiety. QUESTIONS: Given the above history — How would YOU interpret the initial ECG that is shown in Figure-1 ? Does the patient's age infuence your interpretation?

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Acute chest pain, right bundle branch block, no STEMI criteria, and negative initial troponin.

Dr. Smith's ECG Blog

Written by Pendell Meyers A man in his 40s called EMS for acute chest pain that awoke him from sleep, along with nausea and shortness of breath. His history included known heart failure with prior EF 18%, insulin dependent diabetes, and polysubstance abuse. Vitals were within normal limits except for tachypnea. Here are his EMS ECGs along with the Queen of Hearts interpretations below each one: EMS1 0650 EMS2 0707 Click here to sign up for Queen of Hearts Access The ECGs show RBBB and LAFB, with

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Wearable heart monitor increases diagnosis of irregular heart rhythm

Science Daily - Stroke

Wearable, long-term continuous heart monitors helped identify 52% more cases of atrial fibrillation compared to usual care, but that did not lead to a reduction in hospitalizations due to stroke, according to a new study.

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Falling May Be a Harbinger of Dementia in Older Adults

Med Page Today

(MedPage Today) -- A new diagnosis of Alzheimer's disease or related dementia was more common after falls than after other traumatic injuries, an analysis of Medicare claims data showed. The study assessed nearly 2.5 million older adults who had.

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Happy with your life? Research links contentment with fewer heart attacks and strokes

American Heart News - Heart News

Research Highlights: People who are satisfied with their lives or feel contentment or well-being may be less likely to develop heart disease and stroke than their unsatisfied counterparts. The analysis of health records for more than 120,000 adults.

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Happy with your life? Research links contentment with fewer heart attacks and strokes

Medical Xpress - Cardiology

People who are content with their lives or feel a sense of well-being may be less likely to develop heart disease and/or stroke compared to those with a lower sense of well-being, according to a new analysis published today (Sept. 18) in the Journal of the American Heart Association.

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NKT cells promote Th1 immune bias to dengue virus that governs long-term protective antibody dynamics

Journal of Clinical Investigation - Cardiology

NKT cells are innate-like T cells, recruited to the skin during viral infection, yet their contributions to long-term immune memory to viruses are unclear. We identified granzyme K, a product made by cytotoxic cells including NKT cells, as linked to induction of Th1-associated antibodies during primary dengue virus (DENV) infection in humans. We examined the role of NKT cells in vivo using DENV-infected mice lacking CD1d-dependent (CD1ddep) NKT cells.

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Acute artery occlusion -- which one?

Dr. Smith's ECG Blog

Written by Willy Frick with edits by Ken Grauer A woman in her 70s with a history of hypertension presented with acute onset shortness of breath. She was out walking her dog when she developed sudden dizziness and light-headedness. When EMS found her, she was dyspneic and diaphoretic. Her ECG is shown below: What do you think? The conventional machine algorithm interpreted this ECG as STEMI.

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How many people have A-Fib? Three times more than we thought

Science Daily - Heart Disease

Atrial fibrillation, a rapid, irregular heart beat that can lead to stroke or sudden death, is three times more common than previously thought, affecting nearly 5% of the population, or 10.5 million U.S. adults, according to new estimates.

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Up to 1 in 5 Dementia Cases May Be Attributable to Vision Impairment

Med Page Today

(MedPage Today) -- Up to one in five prevalent dementia cases may be attributable to impaired vision, a cross-sectional analysis suggested. In a study of nearly 2,800 older Americans, the population attributable fraction (PAF) of prevalent dementia.

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Measure of body roundness may help to predict risk of cardiovascular disease

American Heart News - Heart News

Research Highlights: Body roundness index — a measure to reflect abdominal body fat and height that some health care professionals believe better reflects the proportion of body fat and visceral fat than body mass index — may help to predict a.

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Study shows estrogen blocker treatment does not increase risk of coronary heart disease in breast cancer patients

Medical Xpress - Cardiology

New evidence shows that extended estrogen suppression treatment using aromatase inhibitors for hormone receptor-positive postmenopausal breast cancer is safe; it does not increase the risk of coronary artery calcification, a sign of active coronary atherosclerosis, as some prior studies had indicated.

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Higher Cardiovascular Health Reduced Risk of Gout

HCPLive

Higher Life’s Essential 8 score was associated with higher CVH scores in US adults.

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An elderly male with shortness of breath

Dr. Smith's ECG Blog

A 70-something y.o. male presents to triage with shortness of breath. He reports significant chest pain at the base of his scapula on the right side along with new shortness of breath. ECG 1 at time zero EARLY REPOLARIZATION ABNORMAL ECG ED final official overread: "early repol vs hyperacute T, minimal changes from previous (previous shown below)" What do YOU think?

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The heart of the question: Who can get Medicare-covered weight loss medicine?

Science Daily - Heart Disease

With Medicare now covering semaglutide for people with obesity and cardiovascular disease who don't have diabetes, a study looks at who that might include, depending on what cutoffs prescription plans apply.

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Study Finds More Heart Defects in Kids Conceived With ART

Med Page Today

(MedPage Today) -- Kids born via assisted reproductive technology (ART) had higher risk of congenital heart defects (CHDs), though the absolute risk difference was small, an observational Nordic study of 7.7 million children found. Major CHDs.

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High blood pressure a concern for adolescents and young adults in U.S.

American Heart News - Heart News

Research Highlights: In the first study, nearly 23% of young adults (ages 18-39 years) included in the NHANES 2017-2020 datasets had high blood pressure (130/80 mm Hg or greater). In addition, they were more likely to self-report being uninsured, food.

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Soil and water pollution and cardiovascular disease

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 25 September 2024; doi:10.1038/s41569-024-01068-0 In this Review, Münzel and colleagues describe the adverse effects of soil and water pollution, including heavy metal, pesticide, and microplastic and nanoplastic pollution, on cardiovascular health and provide an overview of the eco-disruptive causes of this pollution.

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Reagan Udall Foundation for FDA Facilitates Discussion on Urgent Needs in PTSD Therapy

HCPLive

The Reagan Udall Foundation hosted a meeting on PTSD treatment needs, with experts and stakeholders highlighting gaps and potential therapies, including MDMA-assisted therapy.

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The Computer and Overreading Cardiologist call this completely normal. Is it?

Dr. Smith's ECG Blog

This is another case sent by the undergraduate (who is applying to med school) who works as an EKG tech. The undergraduate is now willing to identify himself: Hans Helseth. A 56 year old male with a history of diabetes, dyslipidemia, hypertension, and coronary artery disease presented to the emergency department with sudden onset weakness, fatigue, lethargy, and confusion.

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Breakthrough is a game changer in heart valve technology

Science Daily - Heart Disease

When a patient needs a new heart valve, the current mechanical and tissue replacements each have strengths and weaknesses. Now, a team of researchers believe they have found a way to harness the strengths of both technologies in a way that could be life-changing -- and life-saving -- for many.

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Afib Ablation Delivers in First Sham-Controlled Study

Med Page Today

(MedPage Today) -- LONDON -- Pulmonary vein isolation (PVI) produced real short-term improvements for people with atrial fibrillation (Afib or AF), according to the first sham-controlled trial on the subject. Continuous monitoring by implantable.

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A correctable immune niche for epithelial stem cell reprogramming and post-viral lung diseases

Journal of Clinical Investigation - Cardiology

Epithelial barriers are programmed for defense and repair but are also the site of long-term structural remodeling and disease. In general, this paradigm features epithelial stem cells (ESCs) that are called on to regenerate damaged tissues but can also be reprogrammed for detrimental remodeling. Here we identified a Wfdc21-dependent monocyte-derived dendritic cell (moDC) population that functioned as an early sentinel niche for basal ESC reprogramming in mouse models of epithelial injury after

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