July, 2024

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Data-independent LC-MS/MS analysis of ME/CFS plasma reveals a dysregulated coagulation system, endothelial dysfunction, downregulation of complement machinery

Cardiovascular Diabetology

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic condition that is characterized by unresolved fatigue, post-exertion symptom exacerbation (PESE), cognitive dysfunction, or.

Research 145
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COVID May Affect Type 1 Diabetes in Kids, and Not in a Good Way

Med Page Today

(MedPage Today) -- COVID-19 may accelerate progression of presymptomatic type 1 diabetes in youth, a German study suggested. Incidence of clinical type 1 diabetes nearly doubled after the pandemic started among 591 youth ages 1 to 16 known to.

COVID-19 145
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Dietary patterns to promote cardiometabolic health

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 17 July 2024; doi:10.1038/s41569-024-01061-7 Various dietary patterns have been proposed to improve cardiometabolic health. In this Review, Pagidipati et al. emphasize the commonalities between recommendations on what to eat (Mediterranean, Dietary Approaches to Stop Hypertension and low-carbohydrate or ketogenic diets) and the possible benefits of time-restricted eating and intermittent fasting.

Diet 144
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Survey Details General Public's Eroding Trust Level with Healthcare After COVID-19

HCPLive

Trust in physicians and hospitals dropped from over 70% in 2020 to under 50% in 2024, with declines seen across all demographics, a new survey shows.

COVID-19 140
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Study identifies 18 proteins linked to heart failure, frailty

Medical Xpress - Cardiology

An analysis of blood samples from thousands of study participants, led by researchers at UT Southwestern Medical Center, revealed 18 proteins associated with both heart failure and frailty, conditions that commonly develop in late life. Their findings, published in JAMA Cardiology, could lead to new strategies to jointly predict risk, administer preventive approaches, or treat these conditions, which often occur together.

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White adipocytes in subcutaneous fat depots require KLF15 for maintenance in preclinical models

Journal of Clinical Investigation - Cardiology

Healthy adipose tissue is essential for normal physiology. There are 2 broad types of adipose tissue depots: brown adipose tissue (BAT), which contains adipocytes poised to burn energy through thermogenesis, and white adipose tissue (WAT), which contains adipocytes that store lipids. However, within those types of adipose, adipocytes possess depot and cell-specific properties that have important implications.

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New research explores alcohol’s impact on the heart

American Heart News - Heart News

Research Highlights: Two new, basic research studies in rodents (mice and rats) analyzed the impacts that alcohol may have on the heart. In a mouse study, abnormal heart rhythms that can occur after a pattern of repeated simulation of binge drinking.

Research 135

More Trending

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Two researchers to receive first-ever Ralph L. Sacco Scholarships for Brain Health

American Heart News - Stroke News

DALLAS and MINNEAPOLIS, July 2, 2024 — The American Academy of Neurology and the American Heart Association have awarded the first-ever Ralph L. Sacco Scholarships for Brain Health to two researchers, Patrick Devlin, Ph.D., of Houston, Texas, and Cyprien.

Research 134
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Top Gene Therapy News at ASRS 2024

HCPLive

A recap of the 5 most popular topics related to gene therapy in ophthalmology coming from the 42nd American Society of Retina Specialists meeting.

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What are treatment options for this rhythm, when all else fails?

Dr. Smith's ECG Blog

Written By Magnus Nossen — with edits by Ken Grauer and Smith. The patient in today’s case is a previously healthy 40-something male who contacted EMS due to acute onset crushing chest pain. The pain was 10/10 in intensity radiating bilaterally to the shoulders and also to the left arm and neck. The below ECG was recorded. The ECG shows obvious STEMI(+) OMI due to probable proximal LAD occlusion.

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Study discovers connection between between heart and brain in KBG syndrome

Medical Xpress - Cardiology

A new study sheds light on a medical question scientists have long wondered: why do 40% of children with the rare neurodevelopmental disorder KBG syndrome have heart defects? The research now points to a critical link between the heart and the brain. The research is published in the journal Nature Communications.

Research 132
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Palliative care beneficial to manage symptoms, improve quality of life for people with CVD

American Heart News - Heart News

Statement Highlights: Palliative medication management focuses on providing relief from symptoms and enhancing quality of life for people with cardiovascular disease throughout the various stages of the disease. Decisions about initiating, adjusting.

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New Alzheimer's Mimic Identified

Med Page Today

(MedPage Today) -- A new memory-loss syndrome that mimics the clinical features of Alzheimer's disease was identified, researchers said. "We propose a set of clinical criteria for a limbic-predominant amnestic neurodegenerative syndrome [LANS.

Research 138
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30-year risk of cardiovascular disease may help inform blood pressure treatment decisions

Science Daily - Heart Disease

According to a new study, both 30-year risk for cardiovascular disease in addition to 10-year risk may be considered in making decisions about when to initiate high blood pressure medication.

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Long COVID Linked to Significantly Worse Rheumatic Disease Activity

HCPLive

Patients with inflammatory arthritis experiencing “long COVID” reported significantly worse disease activity.

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Resuscitated from ventricular fibrillation. Should the cath lab be activated?

Dr. Smith's ECG Blog

This patient was witnessed by bystanders to collapse. They started CPR. EMS arrived and found him in Ventricular Fibrillation (VF). He was defibrillated into VT. He then underwent dual sequential defibrillation into asystole. After 1 mg of epinephrine they achieved ROSC. Total prehospital meds were epinephrine 1 mg x 3, amiodarone 300 mg and 100 mL of 8.4% sodium bicarbonate.

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The top heart hospital in every state

Becker's Hospital Review - Cardiology

Discover the top heart hospitals in every state according to U.S.

Hospital 124
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Increasing cardiac ketones may help heart failure in mouse study

American Heart News - Heart News

Research Highlights: In mice with heart failure with preserved ejection fraction (HFpEF), increasing ketone supply to the heart allowed their hearts to utilize more ketones and produce more energy. Researchers hope this study may help to improve our.

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Nasal Sprays for Respiratory Infections; Paxlovid in COVID Prevention

Med Page Today

(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center.

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Artificial intelligence speeds up heart scans, saving doctors' time, and could lead to better treatment for heart conditions

Science Daily - Heart Disease

Researchers have developed a groundbreaking method for analysing heart MRI scans with the help of artificial intelligence, which could save valuable time and resources, as well as improve care for patients.

Research 127
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HeartBeam’s Artificial Intelligence Algorithm Combined with Vectorcardiography (VCG) Outperforms Expert Cardiologists in Detecting Arrhythmias

DAIC

mtaschetta-millane Mon, 07/15/2024 - 11:18 July 15, 2024 — HeartBeam, Inc. , a medical technology company focused on transforming cardiac care through the power of personalized insights, today announced new study data demonstrating that HeartBeam AI combined with vectorcardiography (VCG) outperformed an expert panel of heart rhythm cardiologists in detecting atrial flutter.

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Stroke recovery: It's in the genes

Science Daily - Stroke

New research has found that specific genes may be related to the trajectory of recovery for stroke survivors, providing doctors insights useful for developing targeted therapies.

Stroke 123
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Why skipping breakfast can be bad for your heart

Medical Xpress - Cardiology

Some say that breakfast is the most important meal of the day. Is it really? That's up for debate. However, skipping the first meal is not the healthiest choice and can even put someone at risk for health issues. In this Mayo Clinic Minute, Dr. Francisco Lopez-Jimenez, a Mayo Clinic cardiologist, explains why.

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Localized translation and sarcomere maintenance requires ribosomal protein SA in mice

Journal of Clinical Investigation - Cardiology

Cardiomyocyte sarcomeres contain localized ribosomes, but the factors responsible for their localization and the significance of localized translation are unknown. Using proximity labeling, we identified ribosomal protein SA (RPSA) as a Z-line protein. In cultured cardiomyocytes, the loss of RPSA led to impaired local protein translation and reduced sarcomere integrity.

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Dementia Risk Drops With Shingrix Vaccine

Med Page Today

(MedPage Today) -- The recombinant shingles vaccine (Shingrix) was associated with a larger reduction in dementia than the live shingles vaccine (Zostavax), an analysis of more than 200,000 U.S. older adults showed. Over a 6-year follow-up period.

Dementia 133
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Combining popular diabetes drugs offers complementary heart and kidney benefits

Science Daily - Heart Disease

New research shows combined use of sodium glucose co-transporter 2 inhibitors (SGLT2is) and glucagon-like peptide-1 receptor agonists (GLP1-RAs) is likely to offer additional protection against heart and kidney disease in patients with diabetes.

Diabetes 126
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Artificial Intelligence Speeds Up Heart Scans, Leading to Efficiency and Improving Outcomes

DAIC

Pankaj Garg, MD mtaschetta-millane Fri, 07/12/2024 - 11:14 July 12, 2024 — Researchers have developed a groundbreaking method for analyzing heart MRI scans with the help of artificial intelligence , which could save valuable NHS time and resources, as well as improve care for patients. The teams from the Universities of East Anglia (UEA), Sheffield and Leeds created an intelligent computer model that utilizes AI to examine heart images from MRI scans in a specific view known as the four-chamber

Outcomes 122
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30-year risk of cardiovascular disease may help inform blood pressure treatment decisions

American Heart News - Heart News

Research Highlights: A comparison of two tools for calculating cardiovascular disease risk found that if only the current 10-year risk thresholds are applied, fewer adults may be recommended for blood pressure-lowering medication. The tools, The.

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Early surgery to prevent embolic events in patients with infective endocarditis: a comprehensive review

Journal of Cardiothoracic Surgery

Infective endocarditis (IE) is a dangerous and lethal illness with high mortality rates. One of the main indications for surgery according to the guidelines is prevention of embolic events. However, uncertaint.

Embolism 119
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SGLT2 Inhibitor, GLP-1 RA Combination Improves Cardiovascular, Kidney Outcomes in Diabetes

HCPLive

Findings from a meta-analysis examining 12 trials including more than 70,000 patients with diabetes support combining SGLT2 inhibitors and GLP-1 RAs.

Diabetes 119
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Semaglutide May Be Linked to Condition That Causes Blindness

Med Page Today

(MedPage Today) -- Use of the GLP-1 receptor agonist semaglutide (Ozempic, Wegovy) may be linked with an increased risk of the second most common form of optic neuropathy, a retrospective study suggested. Over a mean follow-up of nearly 3 years.

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Physical activity improves early with customized text messages in patients with heart problems

Science Daily - Heart Disease

Personalized text messages effectively promoted increased physical activity for patients after significant heart events -- such as a heart attack or surgery -- but those effects later diminished. Researcher say the results show incredible promise for simple, low cost interventions delivered through mobile technology and their potential to help prevent secondary cardiovascular events in patients.

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Rapid and Accurate Prediction Model for Cardiac Arrest Treatment

DAIC

R-EDByUS score features variables using only prehospital resuscitation data. Image courtesy of Takenobu Shimada, Osaka Metropolitan University (CC BY 4.0, [link] mtaschetta-millane Mon, 07/29/2024 - 09:09 July 29, 2024 — When it comes to treating cardiac arrest, acting quickly can mean the difference between life and death. Researchers from Osaka Metropolitan University have developed a new scoring model, using only prehospital resuscitation data, that accurately predicts neurological outcomes o

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A man in his 50s with unwitnessed VF arrest, defibrillated to ROSC, and no STEMI criteria on post ROSC ECG. Should he get emergent angiogram?

Dr. Smith's ECG Blog

Written by Pendell Meyers A man in his 50s was found by his family in cardiac arrest of unknown duration. His family started CPR and called EMS, who arrived to find him in ventricular fibrillation. 15 minutes after EMS arrival, after at least 6 defibrillations, the patient achieved sustained ROSC. He arrived to the ED with severe hypotension, heart rate in the 70s, unable to follow commands but moving all extremities requiring restraint and sedation, respiratory rate around 24/min being supporte

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The molecule that could alleviate stroke-related brain injury

Science Daily - Stroke

New research identifies novel path to protecting the brain from stroke-induced damage.

Stroke 117
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Few Youth Receive Lipid Screening, Highlighting Missed Opportunity to Reduce CVD Risk

HCPLive

Despite recommendations, an analysis of more than 3.2 million youths suggests fewer than 15% of children/adolescents receive lipid screening.

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Mediterranean Diet Good for Kids, Teens Too

Med Page Today

(MedPage Today) -- The Mediterranean diet improved cardiometabolic health among kids and teens, a meta-analysis of randomized clinical trials affirmed. Interventions following the diet's characteristic emphasis on fruit, vegetables, olive oil.

Diet 133