May, 2024

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ECG Blog #432 — "Should I Shock this Patient?"

Ken Grauer, MD

I was sent the ECG in Figure-1 — without the benefit of any history. Is this VT? What is the 1st thing — that YOU would do? Figure-1: I was sent this ECG without any history. Is this VT? MY Thoughts on Today’s CASE: As tempting as it might be to reach for the defibrillator on seeing the ECG shown in Figure-1 — My initial reaction was different. At 1st glance , my impression from seeing ECG #1 — was that the rhythm is very fast and irregular — with a highly variable QRS morphology — and, without

Blog 165
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Dementia Mortality Tied to Olive Oil Consumption

Med Page Today

(MedPage Today) -- Higher olive oil intake was associated with a lower risk of dementia-related mortality, a prospective study of 90,000 healthcare professionals showed. Eating at least 7 g of olive oil daily -- about a half tablespoon --.

Dementia 145
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Heart healthy behaviors may help reverse rapid cell aging

American Heart News - Heart News

Research Highlights: The benefits gained from better heart health may be related to a process involved in the aging of the body and its cells, researchers found in a study of more than 5,000 adults with a mean age of 56 years. People with rapid cell.

Research 133
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Transcutaneous Pacing: Part 2

EMS 12-Lead

TCP in the ROSC Patient: False Electrical Capture at 75mA Josh Kimbrell, NRP @joshkimbre Judah Kreinbrook, EMT-P @JMedic2JDoc This is the second installment of a blog series showing how transcutaneous pacing (TCP) can be difficult and how you can improve your skills. We will be using redacted information from different cases where paramedics attempted TCP in the field.

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Evaluating Safety of Novel LDL Management Mechanism

HCPLive

Deepak Bhatt, MD, MPH, MBA, reviews the efficacy and safety data of inclisiran, highlighting its long-term effects and noting that injection site reactions are among the most prominent adverse reactions associated with this medication.

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Study finds fat cells influence heart health in Chagas disease

Medical Xpress - Cardiology

Jyothi Nagajyothi, Ph.D. and her laboratory at the Hackensack Meridian Center for Discovery and Innovation (CDI) have identified what may be the main mechanism for how chronic Chagas disease, a parasitic infection affecting millions of people worldwide, can cause irreversible and potentially fatal heart damage.

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ECG Blog #430 — Just a Regular LBBB ECG?

Ken Grauer, MD

The ECG in Figure-1 — was obtained from an older man who had just completed dialysis — and , is now complaining of abdominal discomfort that radiates to his chest. The consultant interpreted this tracing as “LBBB” ( L eft B undle B ranch B lock ) — but not indicative of anything acute. QUESTIONS: Do you agree with the consultant’s interpretation? How would YOU approach this case?

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More Trending

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Brief anger may impair blood vessel function

American Heart News - Heart News

Research Highlights: When adults became angry after remembering past experiences, the function of cells lining the blood vessels was negatively impaired, which may restrict blood flow. Previous research has found that this may increase the risk of.

Research 133
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New Treatment in Pipeline for Patients with Hypertrophic Cardiomyopathy

DAIC

Getty Images milla1cf Tue, 05/14/2024 - 13:00 May 14, 2024 — One of the most common genetic heart diseases worldwide, hypertrophic cardiomyopathy (HCM) causes the walls of the left ventricle to become thick and stiff. In about 70 percent of cases, patients with HCM experience obstruction to blood flow, which increases pressures in the heart and can lead to chest pain, shortness of breath and reduced exercise capacity.

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Insulin sensitivity estimates and their longitudinal association with coronary artery disease in type 1 diabetes. Does it matter?

Cardiovascular Diabetology

Insulin resistance and chronic kidney disease are both associated with increased coronary artery disease risk. Many formulae estimating glucose disposal rate in type 1 diabetes infer insulin sensitivity from c.

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An undergraduate who is an EKG tech sees something. The computer calls it completely normal. How about the physicians?

Dr. Smith's ECG Blog

This was sent by an undergraduate (not yet in medical school, but applying now) who works as an ED technician (records all EKGs, helps with procedures, takes vital signs) and who reads this blog regularly. Edited by Smith He also sent me this great case. A 63 year old man with a history of hypertension, hyperlipidemia, prediabetes, and a family history of CAD developed chest pain, shortness of breath, and diaphoresis after consuming a large meal at noon.

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ECG Blog #431 — My New ECG-Rhythm Podcasts!

Ken Grauer, MD

I recently recorded a series of 4 podcasts regarding KEY concepts in ECG interpretation. Easy LINKS — tinyurl.com/KG-ECG-Podcasts — [link] — Other ECG Audio PEARLS I previously made for my ECG Blog can be found in the right column of each page on this blog just below this icon — under, "ECG Audio PEARLS". My New E CG P odcasts ( 5/28/2024 ): These podcasts are part of the Mayo Clinic Cardiovascular CME Podcasts Series ( "Making Waves" ) — hosted by Dr.

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Some Patients Suffered Psychiatric Issues After Ozempic Initiation

Med Page Today

(MedPage Today) -- NEW YORK CITY -- Some patients who newly started a GLP-1 receptor agonist quickly developed psychiatric symptoms, a few case reports detailed here. One case involved a female, age 42, with a history of bipolar I disorder.

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Significant gaps between science of obesity and the care patients receive

American Heart News - Heart News

Statement Highlights: More than 40% of adults in the United States live with obesity, and the percentage of people living with obesity continues to increase dramatically. While experts have learned a great deal about the causes of obesity and.

Obesity 132
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Ep 195 Management of Subarachnoid Hemorrhage

ECG Cases

Once the diagnosis of nontraumatic subarachnoid hemorrhage (SAH) has been made, our job is not done. Mortality in SAH patients can be up to 30% even without neurological deficit. Paying attention to the time-sensitive details of ED management of SAH patients can have a significant impact on their outcome. In this second part of our 2-part podcast series on subarachnoid hemorrhage with Dr.

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The mechanosensory channel PIEZO1 functions upstream of angiopoietin/TIE/FOXO1 signaling in lymphatic development

Journal of Clinical Investigation - Cardiology

Lymphedema is a debilitating disease with no effective cure and affects an estimated 250 million individuals worldwide. Prior studies have identified mutations in piezo-type mechanosensitive ion channel component 1 (PIEZO1), angiopoietin 2 (ANGPT2), and tyrosine kinase with Ig-like and EGF-like domains 1 (TIE1) in patients with primary lymphedema. Here, we identified crosstalk between these molecules and showed that activation of the mechanosensory channel PIEZO1 in lymphatic endothelial cells (

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Wide complex tachycardia, resistant to cardioversion. Some fascinating features here.

Dr. Smith's ECG Blog

An elderly dialysis patient presented with chest pain. She has poor LV function. Previous echo 4 months ago (confirmed with ED bedside echo): The estimated left ventricular ejection fraction is 30%. Severely decreased LV function. Regional wall motion abnormality-inferior, inferolateral, septum, anterolateral, anterior and apex, lateral. Here is her ECG: Regular Wide Complex Tachycardia.

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Night-time heat significantly increases the risk of stroke

Science Daily - Stroke

Researchers show that nocturnal heat significantly increases the risk of stroke. The findings can contribute to the development of preventive measures: With them, the population can better protect themselves against the risks of climate change with increasingly frequent hot nights. In addition, knowledge of the consequences of hot nights can improve patient care.

Stroke 118
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Young-Onset Dementia Tied to Preeclampsia

Med Page Today

(MedPage Today) -- Preeclampsia raised the risk of young-onset dementia, a prospective study of nearly 2 million women in France showed. Compared with pregnancies without hypertensive disorders, preeclampsia more than doubled the risk of dementia.

Dementia 140
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New postpartum care recommendations target CVD risk

American Heart News - Heart News

DALLAS, May 16, 2024 — Pregnancy-related deaths in the U.S. have risen 140% over the past three decades and cardiovascular disease is the leading cause.[1] Despite existing medical guidance on pregnancy and cardiovascular health, current trends in health.

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Documentary Led by HonorHealth Research Institute Focuses on Injuries to Doctors and Nurses Working in Cardiology

DAIC

milla1cf Tue, 05/07/2024 - 12:54 May 7, 2024 — HonorHealth Research Institute ’s David G. Rizik , M.D., narrates and is a co-producer of a documentary focused on radiation and orthopedic injuries suffered by doctors and nurses who work in cardiac catheterization laboratories where they apply the very latest non-surgical technologies to treat the world’s leading cause of death, heart disease.

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RNF4 sustains Myc-driven tumorigenesis by facilitating DNA replication

Journal of Clinical Investigation - Cardiology

The mammalian SUMO-targeted E3 ubiquitin ligase Rnf4 has been reported to act as a regulator of DNA repair, but the importance of RNF4 as a tumor suppressor has not been tested. Using a conditional-knockout mouse model, we deleted Rnf4 in the B cell lineage to test the importance of RNF4 for growth of somatic cells. Although Rnf4–conditional-knockout B cells exhibited substantial genomic instability, Rnf4 deletion caused no increase in tumor susceptibility.

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Chest pain: Are these really "Nonspecific ST-T wave abnormalities", as the cardiologist interpretation states?

Dr. Smith's ECG Blog

Written by Jesse McLaren, with a very few edits by Smith A 60-year-old presented with chest pain. The ECG did not meet STEMI criteria, and the final cardiology interpretation was “ST and T wave abnormality, consider anterior ischemia”. But are there any other signs of Occlusion MI? There’s only minimal ST elevation in III, which does not meet STEMI criteria of 1mm in two contiguous leads.

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Abnormal vascular thickness and stiffness in young adults with type 1 diabetes: new insights from cutting-edge ultrasound modalities

Cardiovascular Diabetology

Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality in patients with Type 1 Diabetes (T1D). Early markers of CVD include increased carotid intima-media thickness (CIMT) and pulse.

Diabetes 115
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Alzheimer's Biomarkers Linked With Plasma Leptin Levels

Med Page Today

(MedPage Today) -- Plasma leptin levels were linked with Alzheimer's disease PET pathology in cognitively unimpaired older adults, a longitudinal cohort study in Korea showed. Over 2 years, lower baseline plasma leptin was associated with a greater.

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America’s CKM Syndrome Problem

CardiacWire

A new JAMA study revealed that a shocking 90% of US adults are at risk of developing cardiovascular-kidney-metabolic (CKM) syndrome, underscoring the need for preventative action before we face a wave of CKM-related heart disease. Officially published by the AHA six months ago, CKM syndrome defines the connections and risks associated with obesity, type 2 diabetes, chronic kidney disease, and cardiovascular disease.

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Early diagnosis & treatment of peripheral artery disease essential to improve outcomes, reduce amputation risk

American Heart News - Heart News

Guideline Highlights: The new joint guideline from the American Heart Association and the American College of Cardiology provides recommendations to guide clinicians in the treatment of patients with lower extremity peripheral artery disease (PAD) and.

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Ultrasound Neuromodulation Shows Promise to Treat Pulmonary Hypertension, Feinstein Institutes Research

DAIC

Feinstein Institutes’ Dr. Stavros Zanos is the senior author on the new bioelectronic medicine ultrasound paper. (Credit: Feinstein Institutes) milla1cf Wed, 05/08/2024 - 10:57 May 8, 2024 — Ultrasound could one day complement or even replace drugs to treat diseases. Bioelectronic medicine scientists at The Feinstein Institutes for Medical Research used noninvasive, splenic focused ultrasound stimulation (sFUS) and found they can reduce inflammation and improve symptoms of pulmonary arter

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A young man with palpitations.

Dr. Smith's ECG Blog

A 30-something presented with chest pain, palpitations, and SOB. He has had similar symptoms for 4 years, but has never been evaluated. Here is his presenting ECG, which was sent to me real time, along with the 2nd ECG below: Regular Narrow Fast without P-waves. PSVT. It is very difficult to tell if this is: 1) AVNRT or 2) orthodromic AVRT (Orthodromic AVRT = WPW with orthograde conduction down the AV node and retrograde up an accessory pathway) See Ken Grauer's discussion below in differentiati

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Clinical Quiz: Lp(a) Treatments and Therapeutics Considerations

HCPLive

The final in our 3-part quiz series based on the NLA's 2024 update to their 2019 scientific statement on use of lipoprotein(a) in clinical practice focuses on treatment considerations and therapeutic options for elevated Lp(a).

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Brain Risks Drop When Diet Includes More Minimally Processed Foods

Med Page Today

(MedPage Today) -- A diet high in ultra-processed foods upped the risk of cognitive impairment or stroke, data from the prospective REGARDS study showed. However, risk of either cognitive decline or stroke fell for people who had higher intake.

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Illinois hospital launches 1st-of-its-kind stroke study

Becker's Hospital Review - Cardiology

A team of physicians at Rockford, Ill.-based Mercyhealth Javon Bea Hospital-Riverside participated in a unique stroke study that used patients' stem cells to promote tissue regeneration, it announced May 22.

Hospital 114
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Two decades of studies suggest health benefits associated with plant-based diets

Science Daily - Heart Disease

Vegetarian and vegan diets are generally associated with better status on various medical factors linked to cardiovascular health and cancer risk, as well as lower risk of cardiovascular diseases, cancer, and death, according to a new review of 49 previously published papers.

Diet 117
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American College of Cardiology Announces Care of the Athletic Heart

DAIC

milla1cf Fri, 05/31/2024 - 07:00 May 31, 2024 — In the United States there are over 8 million active athletes. Given the rapid expansion of sports cardiology, cardiovascular care teams must understand contemporary care and practice management strategies for all athletes—from the elite to the exercise enthusiast. The ACC Care of the Athletic Heart conference , taking place in Washington, on June 6-8, aims to provide clinicians with guideline-driven, practical, cardiovascular care strategies to im

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Do you need to be a trained health care professional to diagnose subtle OMI on the ECG?

Dr. Smith's ECG Blog

An undergraduate (not yet in medical school) who works as an ED technician (records all EKGs, helps with procedures, takes vital signs) and who reads this blog regularly arrived at work and happened to glance down and see this previously recorded ECG on a table in the ED. It was recorded at 0530: What do you think? The young ED tech immediately suspected LAD OMI.

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FLOW Trial Fortifies Semaglutide's Role in Chronic Kidney Disease and Type 2 Diabetes

HCPLive

Semaglutide 1.0 mg reduced major kidney disease events and slowed eGFR decline in patients with type 2 diabetes and chronic kidney disease, according to the FLOW trial.

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FDA Warns on Insulin Pump Problem

Med Page Today

(MedPage Today) -- A mobile app used with an insulin pump that led to 224 injuries was recalled by Tandem Diabetes Care, the FDA announced today. The recall is for the 2.7 version of the Apple iOS t:connect mobile app, used in conjunction with.

Diabetes 119