April, 2024

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ECG Blog #426 — Are STEMI Criteria Met?

Ken Grauer, MD

The ECG in Figure-1 — was obtained from a 70-ish year old man with episodic CP ( C hest P ain ) over the previous 2-3 days , being awakened from sleep now for a more severe CP episode. QUESTIONS: In view of this history — How would YOU interpret this ECG? Should you activate the cath lab? Figure-1: The initial ECG in today's case. MY Initial Thoughts on Today's CASE: Although it is difficult from the brief history we are given, to determine the true onset of whatever might be happening — the pat

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Only One Harm From mRNA COVID Vaccines, Report Determines

Med Page Today

(MedPage Today) -- Independent reviewers confirmed a causal relationship between the first mRNA COVID-19 vaccines and myocarditis, and also determined that, more broadly, intramuscular shots can cause a series of shoulder injuries. At the same.

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Ep 193 The Crashing Asthmatic – Recognition and Management of Life Threatening Asthma

ECG Cases

In this part 2 of our 2-part podcast on asthma with Dr. Sameer Mal and Dr. Leeor Sommer, we dig into the recognition and management of life-threatening asthma. We answer such questions as: what are the key elements in recognition of threatening asthma? What are the most time-sensitive interventions required to break the vicious cycle of asthma? What are the best options for dosing and administering magnesium sulphate, epinephrine, fentanyl and ketamine in the management of the crashing asthmatic

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Physical activity lowers cardiovascular disease risk by reducing stress-related brain activity, study finds

Medical Xpress - Cardiology

New research indicates that physical activity lowers cardiovascular disease risk in part by reducing stress-related signaling in the brain.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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More than half a million global stroke deaths may be tied to climate change

Science Daily - Stroke

A changing climate may be linked to growing death and disability from stroke in regions around the world, according to a new study. Researchers found over three decades that non-optimal temperatures, those above or below temperatures associated with the lowest death rates, were increasingly linked to death and disability due to stroke. The study does not prove that climate change causes stroke.

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Ventricular Fibrillation, ICD, LBBB, QRS of 210 ms, Positive Smith Modified Sgarbossa Criteria, and Pacemaker-Mediated Tachycardia

Dr. Smith's ECG Blog

An elderly man collapsed. There was no bystander CPR. Medics found him in ventricular fibrillation. He was defibrillated, but they also noticed that he was being internally defibrillated and then found that he had an implantable ICD. He was unidentified and there were no records available After 7 shocks, he was successfully defibrillated and brought to the ED.

More Trending

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5 Dead and Over 100 Hospitalized From Recalled Japanese Health Supplements

Med Page Today

(MedPage Today) -- TOKYO (AP) -- Five people who took a Japanese health supplement have died and more than 100 have been hospitalized as of Friday, a week after a pharmaceutical company issued a recall of the products, officials said. Osaka.

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ECG Cases 49 – ECG and POCUS for Dyspnea and Chest Pain

ECG Cases

In this ECG Cases blog, Jesse McLaren and Rajiv Thavanathan explore how ECG and POCUS complement each other for patients presenting to the emergency department with shortness of breath or chest pain. They explain complementary diagnostic insights into pericardial effusion and cardiac tamponade, occlusion MI and RV strain. The post ECG Cases 49 – ECG and POCUS for Dyspnea and Chest Pain appeared first on Emergency Medicine Cases.

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Recognizing Stigma's Impact on Care for Alcohol-Related Liver Disease

HCPLive

In the first segment of this HCPLive special report, experts discuss the stigma surrounding alcohol use disorder and alcohol-associated liver disease.

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Researchers identify over 2,000 genetic signals linked to blood pressure in study of over one million people

Science Daily - Heart Disease

Researchers have discovered over a hundred new regions of the human genome, also known as genomic loci, that appear to influence a person's blood pressure. In total, over 2,000 independent genetic signals for blood pressure are now reported, demonstrating that blood pressure is a highly complex trait influenced by thousands of different genetic variants.

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Take the OMI Quiz and Test yourself against the Queen of Hearts

Dr. Smith's ECG Blog

Quiz The PM Cardio Queen of Hearts AI model for ECG interpretation from Powerful Medical is still in its early days. Do you think you can outperform the toddler version of the AI model? Version 2.0 will soon be available with four times the training data. The QoH groups ECGs into OMI and NOT OMI. Each category is subdivided into three levels of confidence.

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“You must go on. I can’t go on. I’ll go on.”

Heart Sisters

“As crazy as this might seem, our research found that life’s stressful turning points do not have to become major crises.” ~ Dr.

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COVID Vaccine Study Finds Small Signal of Seizure Risk in Young Kids

Med Page Today

(MedPage Today) -- Only myocarditis/pericarditis and seizures occurred at higher rates in adolescents and children vaccinated for COVID-19 when compared with historical rates of those outcomes, according to an analysis of safety data from the FDA.

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HeartBeam Presents Positive Results on its Artificial Intelligence Capabilities for Detecting Arrhythmias

DAIC

milla1cf Fri, 04/12/2024 - 20:53 April 12, 2024 — HeartBeam, Inc. , a medical technology company focused on transforming cardiac care through the power of personalized insights, today announced new data demonstrating that applying the company’s artificial intelligence ( AI ) algorithms to vectorcardiography (VCG) showed considerably improved performance in the detection of atrial flutter over single-lead electrocardiograms (ECGs) and similar performance to 12-lead ECGs, the standard for diagno

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FDA Approves Ustekinumab-aekn for PsO, PsA

HCPLive

The FDA approved ustekinumab-aekn for the treatment of moderate to severe plaque psoriasis and active psoriatic arthritis.

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Cardio-fitness cuts death and disease by nearly 20%

Science Daily - Heart Disease

Groundbreaking new research finds that an increased cardio fitness level will reduce your risk of death from any cause by nearly 20%.

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Why Walking Might Save Your Life.

Dr. Paddy Barrett

Walking more is linked to a longer life at a higher quality. That is something we can all aim for. High levels of aerobic fitness, as measured by V02 max, is one of the most powerful predictors of longevity. But for many people regular exercise at even moderate intensities will not be on the cards. I don’t think that is a good idea, but it will be a reality for many.

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Talking about women’s heart disease to medical students

Heart Sisters

Can we do a better job teaching medical and nursing students about women’s unique cardiac issues? The answer might be in these nine teaching modules!

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Neurotechnology Development Must Be Slow and Steady

Med Page Today

(MedPage Today) -- Through my work as a neuroscientist who designs neural implants to monitor the injured brain after severe traumatic brain injuries, stroke, and brain cancers, it has become very clear to me that my field needs to communicate.

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Black and Hispanic people in the United States growing more confident learning and performing CPR

American Heart News - Heart News

DALLAS, April 22, 2024 — More Black and Hispanic people in the U.S. feel confident performing Cardiopulmonary Resuscitation (CPR). A 2023 American Heart Association survey found that 44% of Black Americans now feel confident in performing.

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Inclisiran First Strategy Safe, Effective for LDL-C Control in ASCVD Patients

HCPLive

New data from a phase 3b trial presented at ACC.24 underlines the potential of inclisiran in reducing LDL-C levels among patients with ASCVD.

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Climb stairs to live longer

Science Daily - Heart Disease

Climbing stairs is associated with a longer life, according to new research

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Stroke incidence increases with diabetic retinopathy severity and macular edema in type 1 diabetes

Cardiovascular Diabetology

As the retina is suggested to mirror the brain, we hypothesized that diabetic retinopathy and macular edema are indicative of stroke risk in type 1 diabetes and sought to assess this association in individuals.

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When female doctors treat female patients

Heart Sisters

Several theories have emerged in medicine to explain surprising differences in patient outcomes based on whether our doctor is male or female.

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CDC: COVID Vax Not Linked to Sudden Deaths in Young Adults

Med Page Today

(MedPage Today) -- The hunt for a signal of excess sudden cardiac deaths among young people after COVID-19 vaccination left Oregon health officials empty-handed, they reported. Investigators searched death certificates for Oregon residents 16.

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Good heart health in middle age may preserve brain function among Black women as they age

American Heart News - Heart News

Research Highlights: Middle-aged Black women with better heart health were less likely to show a decline in mental function compared with middle-aged Black women with worse heart health. In this study, heart health was unrelated to cognitive decline.

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A young woman with chest pain, cath lab activated

Dr. Smith's ECG Blog

This case came from a friend whose sister was the patient. She knew I was interested in ECGs, so she took a photo of this one. A young woman presented with acute chest pain. This was her presenting ECG: What do you think? This is clearly Brugada phenotype. There is downsloping ST Elevation in V1 and V2. To an experienced interpreter, it is clearly not due to OMI.

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Unnecessary use of beta-blockers after a heart attack?

Science Daily - Heart Disease

Half of all patients discharged from hospital after a heart attack are treated with beta-blockers unnecessarily, new study suggests.

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Patients with Fibromyalgia Scored Worse in Memory, Attention, Cognitive Function

HCPLive

Without controlling for the severity of symptoms, patients with either fibromyalgia or RA performed worse when compared with controls in terms of cognitive domains including verbal memory, visual memory, and strategic planning.

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7 Things You Can Do To Reduce Your Risk Even If You Already Have Heart Disease.

Dr. Paddy Barrett

This newsletter focuses on prevention. A common feedback I get is that people with existing coronary artery disease feel like it doesn’t apply to them. They feel like they have ‘ missed the boat ’ They have not. And I will explain why. Arguably, applying the principles of prevention offers more bang for buck in the short term for people WITH coronary artery disease than those without coronary artery disease.

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CDC: Premature Mortality for Top Causes of Death Higher in Rural Areas

Med Page Today

(MedPage Today) -- Americans living in rural areas had higher rates of preventable premature mortality from the five leading causes of death than those living in urban areas during the years 2010-2022, and the divide only appears to be growing.

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Adults with congenital heart disease faced higher risk of abnormal heart rhythms

American Heart News - Heart News

Research Highlights: Almost 1 in 5 adults with congenital heart disease living in Israel had or developed an abnormal heart rhythm over five years. Adults with congenital heart disease who developed an irregular heart rhythm in the heart’s upper.

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Is OMI an ECG Diagnosis?

Dr. Smith's ECG Blog

Written by Jesse McLaren A 70 year old with prior MIs and stents to LAD and RCA presented to the emergency department with 2 weeks of increasing exertional chest pain radiating to the left arm, associated with nausea. The pain recurred at rest 90 minutes prior to presentation, felt like the patient’s prior MIs, and was not relieved by 6 sprays of nitro.

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Using stem cell-derived heart muscle cells to advance heart regenerative therapy

Science Daily - Heart Disease

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. However, the risk of arrhythmias following this procedure is reportedly high. In a recent study, researchers tested a novel approach that involves injecting 'cardiac spheroids,' cultured from human stem cells, directly into damaged ventricles.

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Alkaline Water Reduced Pain, Joint Swelling in Patients with Gout

HCPLive

Alkaline water significantly reduced VAS pain scores among patients with gout.

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Small molecules that disrupt RAD54-BLM interaction hamper tumor proliferation in colon cancer chemoresistance models

Journal of Clinical Investigation - Cardiology

RAD54 and BLM helicase play pivotal roles during homologous recombination repair (HRR) to ensure genome maintenance. BLM amino acids (aa 181–212) interact with RAD54 and enhance its chromatin remodeling activity. Functionally, this interaction heightens HRR, leading to a decrease in residual DNA damage in colon cancer cells. This contributes to chemoresistance in colon cancer cells against cisplatin, camptothecin, and oxaliplatin, eventually promoting tumorigenesis in preclinical colon cancer mo

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