April, 2024

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ECG Blog #426 — Are STEMI Criteria Met?

Ken Grauer, MD

The ECG in Figure-1 — was obtained from a 70-ish year old man with episodic CP ( C hest P ain ) over the previous 2-3 days , being awakened from sleep now for a more severe CP episode. QUESTIONS: In view of this history — How would YOU interpret this ECG? Should you activate the cath lab? Figure-1: The initial ECG in today's case. MY Initial Thoughts on Today's CASE: Although it is difficult from the brief history we are given, to determine the true onset of whatever might be happening — the pat

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Only One Harm From mRNA COVID Vaccines, Report Determines

Med Page Today

(MedPage Today) -- Independent reviewers confirmed a causal relationship between the first mRNA COVID-19 vaccines and myocarditis, and also determined that, more broadly, intramuscular shots can cause a series of shoulder injuries. At the same.

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Ep 193 The Crashing Asthmatic – Recognition and Management of Life Threatening Asthma

ECG Cases

In this part 2 of our 2-part podcast on asthma with Dr. Sameer Mal and Dr. Leeor Sommer, we dig into the recognition and management of life-threatening asthma. We answer such questions as: what are the key elements in recognition of threatening asthma? What are the most time-sensitive interventions required to break the vicious cycle of asthma? What are the best options for dosing and administering magnesium sulphate, epinephrine, fentanyl and ketamine in the management of the crashing asthmatic

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Physical activity lowers cardiovascular disease risk by reducing stress-related brain activity, study finds

Medical Xpress - Cardiology

New research indicates that physical activity lowers cardiovascular disease risk in part by reducing stress-related signaling in the brain.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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“You must go on. I can’t go on. I’ll go on.”

Heart Sisters

“As crazy as this might seem, our research found that life’s stressful turning points do not have to become major crises.” ~ Dr.

Research 132
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Researchers identify over 2,000 genetic signals linked to blood pressure in study of over one million people

Science Daily - Heart Disease

Researchers have discovered over a hundred new regions of the human genome, also known as genomic loci, that appear to influence a person's blood pressure. In total, over 2,000 independent genetic signals for blood pressure are now reported, demonstrating that blood pressure is a highly complex trait influenced by thousands of different genetic variants.

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COVID Vaccine Study Finds Small Signal of Seizure Risk in Young Kids

Med Page Today

(MedPage Today) -- Only myocarditis/pericarditis and seizures occurred at higher rates in adolescents and children vaccinated for COVID-19 when compared with historical rates of those outcomes, according to an analysis of safety data from the FDA.

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ECG Cases 49 – ECG and POCUS for Dyspnea and Chest Pain

ECG Cases

In this ECG Cases blog, Jesse McLaren and Rajiv Thavanathan explore how ECG and POCUS complement each other for patients presenting to the emergency department with shortness of breath or chest pain. They explain complementary diagnostic insights into pericardial effusion and cardiac tamponade, occlusion MI and RV strain. The post ECG Cases 49 – ECG and POCUS for Dyspnea and Chest Pain appeared first on Emergency Medicine Cases.

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Ventricular Fibrillation, ICD, LBBB, QRS of 210 ms, Positive Smith Modified Sgarbossa Criteria, and Pacemaker-Mediated Tachycardia

Dr. Smith's ECG Blog

An elderly man collapsed. There was no bystander CPR. Medics found him in ventricular fibrillation. He was defibrillated, but they also noticed that he was being internally defibrillated and then found that he had an implantable ICD. He was unidentified and there were no records available After 7 shocks, he was successfully defibrillated and brought to the ED.

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Recognizing Stigma's Impact on Care for Alcohol-Related Liver Disease

HCPLive

In the first segment of this HCPLive special report, experts discuss the stigma surrounding alcohol use disorder and alcohol-associated liver disease.

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Climb stairs to live longer

Science Daily - Heart Disease

Climbing stairs is associated with a longer life, according to new research

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Talking about women’s heart disease to medical students

Heart Sisters

Can we do a better job teaching medical and nursing students about women’s unique cardiac issues? The answer might be in these nine teaching modules!

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Neurotechnology Development Must Be Slow and Steady

Med Page Today

(MedPage Today) -- Through my work as a neuroscientist who designs neural implants to monitor the injured brain after severe traumatic brain injuries, stroke, and brain cancers, it has become very clear to me that my field needs to communicate.

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Good heart health in middle age may preserve brain function among Black women as they age

American Heart News - Heart News

Research Highlights: Middle-aged Black women with better heart health were less likely to show a decline in mental function compared with middle-aged Black women with worse heart health. In this study, heart health was unrelated to cognitive decline.

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Take the OMI Quiz and Test yourself against the Queen of Hearts

Dr. Smith's ECG Blog

Quiz The PM Cardio Queen of Hearts AI model for ECG interpretation from Powerful Medical is still in its early days. Do you think you can outperform the toddler version of the AI model? Version 2.0 will soon be available with four times the training data. The QoH groups ECGs into OMI and NOT OMI. Each category is subdivided into three levels of confidence.

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Small molecules that disrupt RAD54-BLM interaction hamper tumor proliferation in colon cancer chemoresistance models

Journal of Clinical Investigation - Cardiology

RAD54 and BLM helicase play pivotal roles during homologous recombination repair (HRR) to ensure genome maintenance. BLM amino acids (aa 181–212) interact with RAD54 and enhance its chromatin remodeling activity. Functionally, this interaction heightens HRR, leading to a decrease in residual DNA damage in colon cancer cells. This contributes to chemoresistance in colon cancer cells against cisplatin, camptothecin, and oxaliplatin, eventually promoting tumorigenesis in preclinical colon cancer mo

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Unnecessary use of beta-blockers after a heart attack?

Science Daily - Heart Disease

Half of all patients discharged from hospital after a heart attack are treated with beta-blockers unnecessarily, new study suggests.

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When female doctors treat female patients

Heart Sisters

Several theories have emerged in medicine to explain surprising differences in patient outcomes based on whether our doctor is male or female.

Outcomes 126
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More Cases of Asthma, COPD, Hypertension After Military Burn Pit Exposure

Med Page Today

(MedPage Today) -- Prolonged deployment to military bases with open burn pits was associated with increased risks for certain respiratory and cardiovascular diseases, according to a retrospective cohort study using Veterans Health Administration.

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FDA Approves Ustekinumab-aekn for PsO, PsA

HCPLive

The FDA approved ustekinumab-aekn for the treatment of moderate to severe plaque psoriasis and active psoriatic arthritis.

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HeartBeam Presents Positive Results on its Artificial Intelligence Capabilities for Detecting Arrhythmias

DAIC

milla1cf Fri, 04/12/2024 - 20:53 April 12, 2024 — HeartBeam, Inc. , a medical technology company focused on transforming cardiac care through the power of personalized insights, today announced new data demonstrating that applying the company’s artificial intelligence ( AI ) algorithms to vectorcardiography (VCG) showed considerably improved performance in the detection of atrial flutter over single-lead electrocardiograms (ECGs) and similar performance to 12-lead ECGs, the standard for diagno

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Black and Hispanic people in the United States growing more confident learning and performing CPR

American Heart News - Heart News

DALLAS, April 22, 2024 — More Black and Hispanic people in the U.S. feel confident performing Cardiopulmonary Resuscitation (CPR). A 2023 American Heart Association survey found that 44% of Black Americans now feel confident in performing.

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Using stem cell-derived heart muscle cells to advance heart regenerative therapy

Science Daily - Heart Disease

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. However, the risk of arrhythmias following this procedure is reportedly high. In a recent study, researchers tested a novel approach that involves injecting 'cardiac spheroids,' cultured from human stem cells, directly into damaged ventricles.

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Stroke incidence increases with diabetic retinopathy severity and macular edema in type 1 diabetes

Cardiovascular Diabetology

As the retina is suggested to mirror the brain, we hypothesized that diabetic retinopathy and macular edema are indicative of stroke risk in type 1 diabetes and sought to assess this association in individuals.

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Too Ill for Typical Transplants, Woman Gets a Pig Kidney and Heart Pump Instead

Med Page Today

(MedPage Today) -- A 54-year-old New Jersey woman has become the first-ever patient to undergo combined mechanical heart pump and gene-edited pig kidney transplant surgery, doctors announced. The patient, Lisa Pisano, had heart failure and end.

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Inclisiran First Strategy Safe, Effective for LDL-C Control in ASCVD Patients

HCPLive

New data from a phase 3b trial presented at ACC.24 underlines the potential of inclisiran in reducing LDL-C levels among patients with ASCVD.

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A young woman with chest pain, cath lab activated

Dr. Smith's ECG Blog

This case came from a friend whose sister was the patient. She knew I was interested in ECGs, so she took a photo of this one. A young woman presented with acute chest pain. This was her presenting ECG: What do you think? This is clearly Brugada phenotype. There is downsloping ST Elevation in V1 and V2. To an experienced interpreter, it is clearly not due to OMI.

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Adults with congenital heart disease faced higher risk of abnormal heart rhythms

American Heart News - Heart News

Research Highlights: Almost 1 in 5 adults with congenital heart disease living in Israel had or developed an abnormal heart rhythm over five years. Adults with congenital heart disease who developed an irregular heart rhythm in the heart’s upper.

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Cardiology team performs novel heart artery repair with newly approved device

Science Daily - Heart Disease

Medical researchers have performed a successful transcatheter tricuspid valve repair procedure with a groundbreaking catheter.

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EM Quick Hits 56 – Nitroglycerin in SCAPE, REBOA, Diverticulitis Imaging, CRAO, Penicillin Allergy, Physician Personality

ECG Cases

In this month's EM Quick Hits podcast: Justin Morgenstern on the first RCT of high dose nitroglycerin in SCAPE, Andrew Neill on Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) indications and evidence, Brit Long on indications for CT in suspected diverticulitis, Tahara Bhate on Central Retinal Artery Occlusion (CRAO) and diagnostic error, Matthew McArthur on penicillin allergy labels, myths and penicillin challenges, and Susan Lu on how ED physician personality influences patie

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Cardiac Events Common in Older, Hospitalized RSV Patients

Med Page Today

(MedPage Today) -- More than one in five older adults hospitalized for respiratory syncytial virus (RSV) infection experienced an acute cardiac event, an observational study found. Among 6,248 hospitalized patients 50 or older with laboratory.

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Patients with Fibromyalgia Scored Worse in Memory, Attention, Cognitive Function

HCPLive

Without controlling for the severity of symptoms, patients with either fibromyalgia or RA performed worse when compared with controls in terms of cognitive domains including verbal memory, visual memory, and strategic planning.

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Is OMI an ECG Diagnosis?

Dr. Smith's ECG Blog

Written by Jesse McLaren A 70 year old with prior MIs and stents to LAD and RCA presented to the emergency department with 2 weeks of increasing exertional chest pain radiating to the left arm, associated with nausea. The pain recurred at rest 90 minutes prior to presentation, felt like the patient’s prior MIs, and was not relieved by 6 sprays of nitro.

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ECG Blog #425 — Are there P Waves?

Ken Grauer, MD

I was sent the ECG in Figure-1 — told only that the patient was 70 years old, and had a history of an ASD ( A trial S eptal D efect ). Serum K+ was normal. The patient was hemodynamically stable with ECG #1. QUESTIONS: How would YOU interpret the rhythm in Figure-1 ? Are there P waves? Figure-1: The initial ECG in today's case. MY Initial Thoughts on Today's CASE: Knowing that today's patient has a history of an ASD ( A trial S eptal D efect ) — is relevant to the interpretation of today's inter

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Solving the riddle of the sphingolipids in coronary artery disease

Science Daily - Heart Disease

Investigators have uncovered a way to unleash in blood vessels the protective effects of a type of fat-related molecule known as a sphingolipid, suggesting a promising new strategy for the treatment of coronary artery disease.

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CV Societies Propel Plans Forward for a New Board of Cardiovascular Medicine

DAIC

Getty Images milla1cf Mon, 04/29/2024 - 13:11 April 29, 2024 — Efforts by the American College of Cardiology , the American Heart Association , the Heart Failure Society of America , the Heart Rhythm Society and The Society for Cardiovascular Angiography & Interventions to create a new, independent Board of Cardiovascular Medicine under the American Board of Medical Specialties ( ABMS ) are closer to becoming a reality with the creation of a formal Board of Directors and the announcement by th