October, 2024

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ECG Blog #451 — Premature Closure.

Ken Grauer, MD

I was sent the ECG shown in Figure-1 — told only that the patient was a middle-aged man with septicemia. QUESTIONS: Is this rhythm too fast to be sinus tachycardia? Are flutter waves hidden within the QRS and T waves? Are we seeing the retrograde P waves of AVNRT? Is this ATach ( A trial T achycardia )? Figure-1: The initial ECG in today's case. MY Thoughts on Today’s CASE: In my opinion — none of the above answers are optimal to describe the rhythm in Figure-1.

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New guideline: Preventing a first stroke may be possible with screening, lifestyle changes

American Heart News - Stroke News

Guideline Highlights: Each year in the U.S., over half a million people have a first stroke; however, up to 80% of strokes may be preventable. The new primary prevention of stroke guideline from the American Stroke Association urges health care.

Stroke 143
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Kidney Compass: Semaglutide for Nondiabetic Kidney Disease, with Hiddo Heerspink, PhD, PharmD, at Kidney Week 2024

HCPLive

Hiddo Heerspink, PhD, PharmD, joins the podcast during Kidney Week 2024 to discuss the SMART trial and the potential of semaglutide in people with kidney disease without diabetes.

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COVID-19 infection appeared to increase risk of heart attack & stroke up to 3 years later

American Heart News - Heart News

Research Highlights: An analysis of UK Biobank health data that included adults who had mild to severe COVID-19 before vaccines were available found an increased risk of heart attack, stroke and death among those adults during the nearly three-year.

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Study: Low-level lead poisoning accounts for cognitive deficits in children, risk factors for heart conditions

Medical Xpress - Cardiology

Chronic, low-level lead poisoning is a major risk factor for cardiovascular disease in adults and cognitive deficits in children, even at levels previously thought to be safe, according to a paper by Columbia University Mailman School of Public Health, Simon Fraser University in Canada, and Harvard Medical School, and Boston Children's Hospital.

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Type 2 Diabetes Diagnoses Emerge in Teens Months After COVID

Med Page Today

(MedPage Today) -- Children and teens had an increased risk of being diagnosed with type 2 diabetes after COVID-19 infection, a retrospective cohort study of over 600,000 youth suggested. Adolescents 10 to 19 years old had a 55% higher risk for.

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Spatiotemporal transcriptomic mapping of regenerative inflammation in skeletal muscle reveals a dynamic multilayered tissue architecture

Journal of Clinical Investigation - Cardiology

Tissue regeneration is orchestrated by macrophages that clear damaged cells and promote regenerative inflammation. How macrophages spatially adapt and diversify their functions to support the architectural requirements of actively regenerating tissue remains unknown. In this study, we reconstructed the dynamic trajectories of myeloid cells isolated from acutely injured and early stage dystrophic muscles.

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Kidney Compass: Navigating Clinical Trials

HCPLive

Kidney Compass: Navigating Clinical Trials is a multimedia podcast from HCPLive hosted by Brendon Neuen, MBBS, PhD, and Shikha Wadhwani, MD, MS, aimed at exploring the latest in clinical trials and updates in nephrology.

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Heart failure, atrial fibrillation & coronary heart disease linked to cognitive impairment

American Heart News - Heart News

Statement Highlights: Previous studies have found that 14-81% of patients with heart failure experience some degree of cognitive impairment affecting language, memory or executive function. Evidence also indicates that people with atrial fibrillation.

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History of COVID-19 found to double long-term risk of heart attack, stroke and death

Medical Xpress - Cardiology

A history of COVID-19 can double the risk of heart attack, stroke or death according to new research led by Cleveland Clinic and the University of Southern California.

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ECG Blog #452 — Is this Wide QRS Rhythm VT?

Ken Grauer, MD

The patient whose ECG is shown in Figure-1 — presented with acute dyspnea and hypotension. QUESTION: In Figure-1 — Is the rhythm VT? — How certain are you of your answer? Figure-1: The initial ECG in today's case. ( To improve visualization — I've digitized the original ECG using PMcardio ). == MY Thoughts on the ECG in Figure-1: Although at first glance, the ECG in Figure-1 appears to be wide — this is a false initial impression!

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ASA Advises No Longer Holding GLP-1 Agents Prior to Surgery for Most Patients

Med Page Today

(MedPage Today) -- Most patients should not stop taking GLP-1 receptor agonists prior to elective surgery, according to updated guidance from several medical societies, including the American Society of Anesthesiologists (ASA). This recommendation.

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See what happens when a left main thrombus evolves from subtotal occlusion to total occlusion.

Dr. Smith's ECG Blog

Written by Magnus Nossen The patient in today's case is a male in his 70s with hypertension and type II diabetes mellitus. His wife contacted the ambulance service after the patient experienced an episode of loss of consciousness. The syncope lasted about 2-3 minutes according to his wife. He woke up alert and with chest pain which he also had experienced intermittently over the previous few days.

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Hospitals with highest, lowest 30-day mortality rates for heart attack patients

Becker's Hospital Review - Cardiology

New York City-based NYU Langone hospital had the lowest 30-day mortality rate for heart attack patients in the U.S. between July 1, 2020 and June 30, 2023, according to CMS data released July 31.

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Exploring the Interplay Between Chronic Kidney Disease and Cardiovascular Disease

HCPLive

In this first of this 5-part series, Lerma and Lala-Trindade discuss the interplay between chronic kidney disease and cardiovascular disease.

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Standing more may not reduce cardiovascular disease risk, could increase circulatory issues

Medical Xpress - Cardiology

Standing has gained popularity among people looking to offset the harms of a sedentary lifestyle often caused by spending long days sitting in front of the computer, television or driving wheel. Standing desks have become a popular option among office workers, and in other industries like retail, workers may opt to stand instead of sit.

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Long COVID inflammation damages the heart, study finds

Science Daily - Heart Disease

New research has found inflammatory markers in the blood of long COVID patients which could explain why many experience ongoing cardiovascular issues.

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Physiology Friday #241: How Caffeine Dose and Timing Affect Our Sleep Physiology

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including FSTFUEL electrolytes, Examine.com , and my book “VO2 Max Essentials ” can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.

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Certain Arm Positions Can Lead to Inaccurate Blood Pressure Readings

Med Page Today

(MedPage Today) -- Certain arm positions -- supported on a lap or hanging by the side of the body -- led to significant overestimation of blood pressure readings compared with standardized positioning, a randomized trial in JAMA Internal Medicine.

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Lower your cholesterol early, and stick with it!

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 18 October 2024; doi:10.1038/s41569-024-01095-x Consumption of a high-fat diet leads to the progressive growth of atherosclerotic lesions. Two new studies document that, despite similar overall exposure to high-fat diet over a lifetime, an intermittent consumption of high-fat diet early in life accelerates atherosclerosis compared with continuous consumption of a high-fat diet.

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Stress Triggers IBS Symptoms, Impacts Quality of Life More Than Diet, Study Finds

HCPLive

Mohammad Abuassi, MD, explains how classifying IBS based on triggers can aid the development of effective, personalized approaches to management.

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Standing desks are not the answer to decreasing blood pressure, clinical trial shows

Medical Xpress - Cardiology

Alternating between sitting and standing at work decreases sedentary behavior, but it has no effect on lowering blood pressure, according to a study led by a West Virginia University epidemiologist. Researchers also found that too much standing during work may have negative effects on cardiovascular health.

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50 top hospitals for cardiac surgery: Healthgrades

Becker's Hospital Review - Cardiology

Healthgrades published its 2025 Specialty Excellence Awards recipients Oct. 22. Of those recipients, 50 hospitals were recognized for delivering superior clinical outcomes in cardiac surgery.

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Study offers ‘compelling evidence’ for continuous stroke care improvement

American Heart News - Stroke News

Research Highlights: A retrospective look at Get With The Guidelines® - Stroke registry data from 2003 to 2022 finds substantial and sustained improvements in acute stroke care among those in the quality improvement program. Researchers found.

Stroke 109
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Loneliness Tied to Alzheimer's and Dementia Risk

Med Page Today

(MedPage Today) -- Loneliness increased the risk for all-cause dementia, a meta-analysis that included more than 600,000 people showed. Feeling lonely was tied to a 31% higher risk of overall dementia (HR 1.306, 95% CI 1.197-1.426), according.

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Researchers identify 'sweet spot' for safe surgery after heart attack

Science Daily - Heart Disease

New research suggests older adults wait 3-6 months after a heart attack before elective noncardiac surgery to reduce the risk of serious complications like stroke or another heart attack.

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Exploring the Role, History of Lipoprotein Apheresis, with Laurence Sperling, MD, and Eugenia Gianos, MD

HCPLive

Laurence Sperling, MD, and Eugenia Gianos, MD, discuss the historical context and underutilization of lipoprotein apheresis in part 1 of a 3-part video series.

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New laser light diagnostic tool quickly detects earliest sign of heart attack

Medical Xpress - Cardiology

With heart attacks, every second counts. A new blood test diagnoses them in minutes rather than hours and could be adapted as a tool for first responders and people at home.

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Arm position effect on blood pressure readings: 5 things to know

Becker's Hospital Review - Cardiology

Insufficient arm support can lead to an overestimated blood pressure reading of almost 7mmHG and a potential misdiagnosis of hypertension, according to a study published Oct. 7 in JAMA Internal Medicine.

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The clinical effect of thoracoscopic segmentectomy in the treatment of lung malignancies less than 2CM in diameter

Journal of Cardiothoracic Surgery

To investigate the clinical effect of thoracoscopic segmentectomy in the treatment of lung malignancies less than 2CM in diameter. In this retrospective study, a total of 103 patients with lung cancer who received outpatient or inpatient treatment from December 2020 to May 2022 were selected and divided into the lobectomy group (n = 48) and the segmentectomy group (n = 55) according to different surgical methods.

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A Case of Broca's Aphasia

Med Page Today

(MedPage Today) -- On Sept. 14, 2000, at the age of 72, Lester Schwartz, a psychoanalyst working in New York City, underwent a simple operation for a benign fatty tumor in his stomach. He woke up the next morning in the hospital and realized he.

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AstraZeneca Adds Lp(a) Candidate with CSPC Licensing Move

CardiacWire

AstraZeneca expanded its cardiovascular pipeline this week, signing an exclusive license agreement for CSPC Pharmaceutical Group’s Lp(a) disruptor candidate, YS2302018. The deal comes with a $100M upfront investment that could reach $1.92B depending on further milestones. YS2302018 is a small molecule Lipoprotein (a) disruptor intended to treat dyslipidemia patients by preventing the formation of excess blood lipids.

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Shawn Kwatra, MD: Making the Connection Between Prurigo Nodularis, Atopic Dermatitis, and Itch

HCPLive

In this interview, Kwatra highlighted several key takeaways from his talks on prurigo nodularis, atopic dermatitis, and itch at the Fall Clinical Dermatology Conference.

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Heart signals brain to boost sleep for healing after heart attack, study finds

Medical Xpress - Cardiology

A heart attack can trigger a desire to get more sleep, allowing the heart to heal and reduce inflammation—and this happens because the heart sends special signals to the brain, according to a new Mount Sinai study.

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50 top hospitals for vascular surgery: Healthgrades

Becker's Hospital Review - Cardiology

Healthgrades published its 2025 Specialty Excellence Awards recipients Oct. 22. Of those recipients, 50 hospitals were recognized for delivering superior clinical outcomes in vascular surgery.

Hospital 104
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Microaxial Flow Pump Effects in Infarct-Related Cardiogenic Shock

JAMA Cardiology

This substudy of the Danish-German (DanGer) Shock randomized clinical trial investigates if the use of a microaxial flow pump reduces the need for pharmacological support and what the effects are on hemodynamics and lactate clearance in patients with ST-elevation myocardial infarction–induced cardiogenic shock.

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Ozempic Linked With Lower Risk of Alzheimer's Diagnosis

Med Page Today

(MedPage Today) -- Semaglutide (Ozempic) was tied to a reduced risk of Alzheimer's disease diagnoses in people with type 2 diabetes, observational data showed. In emulation target trials involving more than 1 million eligible diabetes patients.

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