Ken Grauer, MD

AUGUST 29, 2024

The ECG in Figure-1 was obtained from an 80-year old woman — who presented to the ED ( E mergency D epartment ) — with a several hour history of "palpitations" and CP ( C hest P ain ). She was hemodynamically stable at the time ECG #1 was recorded. QUESTIONS: The ECG in Figure-1 was seen by a number of physicians — the majority of whom thought the rhythm was some form of SVT ( S upra V entricular T achycardia ) with LBBB ( L eft B undle B ranch B lock ) aberration.

Blog 157

Blog Chest Pain Tachycardia Heart Disease 157

Med Page Today

AUGUST 16, 2024

(MedPage Today) -- Herpes zoster (shingles) was tied to an elevated risk of subjective cognitive decline, an analysis of 150,000 U.S. healthcare professionals showed. "In three large independent cohorts, herpes zoster was associated with an approximately.

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Journal of Clinical Investigation - Cardiology

AUGUST 1, 2024

Recently developed antimigraine therapeutics targeting calcitonin gene–related peptide (CGRP) signaling are effective, though their sites of activity remain elusive. Notably, the lymphatic vasculature is responsive to CGRP signaling, but whether meningeal lymphatic vessels (MLVs) contribute to migraine pathophysiology is unknown. Mice with lymphatic vasculature deficient in the CGRP receptor (CalcrliLEC mice) treated with nitroglycerin-mediated (NTG-mediated) chronic migraine exhibit reduced pai

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Science Daily - Heart Disease

AUGUST 7, 2024

Lab-grown organs are a long-time 'holy grail' of organ engineering that has yet to be achieved, but new research has brought that goal a big step closer to reality using a new 3D-printing method called co-SWIFT. co-SWIFT prints branching networks of double-layered vessels that are infused with smooth muscle cells and endothelial cells into living human cardiac tissue, and can even replicate patient-specific vascular structures,indicating that it could one day be used for personalized medicine.

Research 134

Research 134

HCPLive

AUGUST 21, 2024

Care for dialysis patients often focuses on kidney health, but experts and a patient stress the need for interdisciplinary care that also addresses sleep health.

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Medical Xpress - Cardiology

AUGUST 20, 2024

Cleveland Clinic researchers have made a significant discovery about how the gut microbiome interacts with cells to cause cardiovascular disease. The study published in Nature Communications found that phenylacetylglutamine (PAG), produced by gut bacteria as a waste product, then absorbed and formed in the liver, interacts with previously undiscovered locations on beta-2 adrenergic receptors on heart cells once it enters the circulation.

Heart Disease 132

Heart Disease Cardiovascular Disease Circulation Research 132

Ken Grauer, MD

AUGUST 16, 2024

The ECG in Figure-1 was obtained from a man in his 40s — who presented to the ED ( E mergency D epartment ) because of CP ( C hest P ain ) and shortness of breath. QUESTIONS: In view of the above history — How would YOU interpret the ECG in Figure-1 ? Based on the history and the patient's initial ECG — the cath lab was activated. Do you agree? Figure-1: The initial ECG in today's case. ( To improve visualization — I've digitized the original ECG using PMcardio ).

Blog 157

Blog Tachycardia Cardiogenic Shock Pulmonary 157

Science Daily - Stroke

AUGUST 13, 2024

A computer algorithm has achieved a 98% accuracy in predicting different diseases by analyzing the color of the human tongue. The proposed imaging system can diagnose diabetes, stroke, anemia, asthma, liver and gallbladder conditions, COVID-19, and a range of vascular and gastrointestinal issues, according to new research.

COVID-19 131

COVID-19 Diabetes Research Stroke 131

Cardiovascular Diabetology

AUGUST 23, 2024

Diabetic kidney disease (DKD) is associated with a higher risk of cardiovascular disease (CVD). Pentoxifylline (PTF), a nonselective phosphodiesterase inhibitor with anti-inflammatory, antiproliferative, and a.

Kidney Disease 129

Kidney Disease Diabetes Atherosclerosis Cardiovascular Disease 129

HCPLive

AUGUST 12, 2024

Mora and Sadreameli join Lungcast to provide a back-to-school health blueprint, including topics like rescue inhalers, vaccination, vaping and air quality.

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Nature Reviews - Cardiology

AUGUST 6, 2024

Nature Reviews Cardiology, Published online: 07 August 2024; doi:10.1038/s41569-024-01064-4 In this Review, Ghofrani and colleagues discuss the mechanisms underlying the development of pulmonary arterial hypertension, provide an overview of approved therapies and describe the predominantly non-vasodilatory drugs that are currently being tested in clinical trials.

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Pulmonary Hypertension 124

Ken Grauer, MD

AUGUST 8, 2024

I was sent the ECG shown in Figure-1 — told only that that this middle-aged woman noted chest tightness and nausea an hour earlier. QUESTIONS: How would YOU interpret the ECG in Figure-1 ? — IF told that this patient arrested shortly after ECG #1 — Does this change your interpretation? Figure-1: The initial ECG in today's case. ( To improve visualization — I've digitized the original EC G using PMcardio ).

Blog 126

Blog STEMI Ischemia 126

Med Page Today

AUGUST 26, 2024

(MedPage Today) -- People with postvaccine myocarditis did not share the typical mid-term complications associated with conventional myocarditis, based on a population-based study from France. With 18-month follow-up of people who had been hospitalized.

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Hospital 143

Physiologically Speaking

AUGUST 23, 2024

Greetings! Welcome to the Physiology Friday newsletter. A quick plug (and discount code!) for an electrolyte supplement I’ve been loving. FSTFUEL combines electrolytes with amino acids to help your body maintain hydration and optimal functioning during exercise or intermittent fasting, so you don't have to choose between fasting and fitness. It’s a zero-sugar electrolyte drink that tastes awesome.

Physiology 121

Physiology Exercise Laboratory Dementia 121

Becker's Hospital Review - Cardiology

AUGUST 26, 2024

High-poverty rural regions in the Southern U.S. have the highest cardiovascular disease-associated death rate, according to a report published Aug. 16 in the Journal of Rural Health.

Cardiovascular Disease 119

Cardiovascular Disease 119

HCPLive

AUGUST 5, 2024

Ocugen will initiate expanded access to OCU400 gene therapy in adults with retinitis pigmentosa prior to BLA approval.

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Science Daily - Heart Disease

AUGUST 27, 2024

A new project has found that people living in neighborhoods where the number of trees and shrubs was more than doubled showed lower levels of a blood marker of inflammation than those living outside the planted areas. General inflammation is an important risk indicator for heart disease and other chronic diseases.

Chronic Disease 119

Chronic Disease Heart Disease 119

Cardiology Update

AUGUST 4, 2024

Despite proven benefits in reducing morbidity and mortality, many heart failure (HF) patients do not receive optimal guideline-directed medical therapy (GDMT). The 2021 European Society of Cardiology guidelines recommend guideline-directed medical therapy (GDMT) for patients with HF with reduced ejection fraction (HFrEF). This includes beta-blockers, ACE inhibitors, ARBs, ARNIs, MRAs, and SGLT2 inhibitors.

Heart Failure 119

Heart Failure ACE Inhibitor COVID-19 Quality of Life 119

Med Page Today

AUGUST 5, 2024

(MedPage Today) -- PHILADELPHIA -- Coffee and tea intake were associated with long-term cognitive changes in older adults, two prospective studies presented at the Alzheimer's Association International Conference (AAIC) suggested. Among 6,001.

Dementia 145

Dementia 145

Physiologically Speaking

AUGUST 30, 2024

Greetings! Welcome to the Physiology Friday newsletter. Thanks to the premium sponsor of this newsletter: FSTFUEL electrolyte supplement. FSTFUEL combines electrolytes with amino acids to help your body maintain hydration and optimal functioning during exercise or intermittent fasting, so you don't have to choose between fasting and fitness. It’s a zero-sugar electrolyte drink that tastes awesome.

Exercise 118

Exercise Physiology Research Innovation 118

ECG Cases

AUGUST 19, 2024

We over-admit low risk acute heart failure patients and under-admit high risk heart failure patients. In this podcast we discuss the diagnostic accuracy of various clinical features, lab tests and imaging modalities for acute heart failure, the 3 validated risk stratification tools and a simple approach to PoCUS for the diagnosis and prognostication of acute heart failure in the ED to improve our diagnostic accuracy and disposition decisions for patients with acute heart failure.

Heart Failure 118

Heart Failure 118

HCPLive

AUGUST 10, 2024

In this episode, hosts are joined by Muthiah Vaduganathan, MD, MPH, for a discussion around topline data updates from the SUMMIT and FINEARTS-HF trials.

Diabetes 124

Diabetes 124

Science Daily - Heart Disease

AUGUST 22, 2024

The researchers looked at data from 4,286 people -- out of a total of 17,605 from the landmark Semaglutide and Cardiovascular Outcomes (SELECT) trial who were randomly assigned either semaglutide or a placebo -- who were followed up over an average of more than three years.

Heart Failure 118

Heart Failure Research Outcomes 118

American Heart News - Heart News

AUGUST 26, 2024

Research Highlights: People diagnosed with unruptured cerebral aneurysms (weakened areas in brain blood vessels) who are being monitored without treatment have a higher risk of developing mental illness compared to those who have not been diagnosed.

Aneurysm 117

Aneurysm Research 117

Med Page Today

AUGUST 29, 2024

(MedPage Today) -- Some terms commonly used to describe observations seen on ultrasound during first-trimester pregnancies are outdated and should be replaced with more descriptive language, a multisociety panel of ob/gyns, radiologists, and emergency.

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Ultrasound 141

Becker's Hospital Review - Cardiology

AUGUST 2, 2024

Discover the groundbreaking work of Boston Children's cardiac surgeons as they perform the first elective partial heart transplant on a 4-year-old boy

Heart Transplant 118

Heart Transplant Transplant 118

Dr. Smith's ECG Blog

AUGUST 2, 2024

Written by Willy Frick A 50 year old man with no medical history presented with acute onset substernal chest pain. His ECG is shown below. Pretty obvious anterior current of injury. This was a machine read STEMI positive OMI. Readers of this blog can easily appreciate the hyperacute T waves in the precordium, clearest in V1-V4. What would you guess is the culprit artery?

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STEMI Ischemia Blog Chest Pain 117

HCPLive

AUGUST 24, 2024

In this systematic review and meta-analysis, the investigators highlighted topical roflumilast’s success in clinical milestones such as IGA and PASI score success.

Plaque 122

Plaque 122

Science Daily - Heart Disease

AUGUST 30, 2024

The appropriate duration of beta-blocker treatment after a heart attack (a myocardial infarction [MI]) is unknown in patients who do not need to take beta-blockers for another reason. In the ABYSS trial, the cardiovascular safety of interrupting beta-blocker could not be shown in comparison with beta-blocker continuation and beta-blocker interruption did not improve quality of life.

Heart Attack 113

Heart Attack Heart attacks Quality of Life Myocardial Infarction 113

American Heart News - Stroke News

AUGUST 19, 2024

Statement Highlights: The latest research indicates that 16% to 85% of people recovering from a stroke experience at least one psychosocial symptom, including depression, anxiety, stress, fatigue and/or decreased quality of life. Critical nursing.

Nursing 113

Nursing Quality of Life Stroke Strokes 113

Med Page Today

AUGUST 15, 2024

(MedPage Today) -- Sitagliptin (Januvia) saw the greatest drop in price among the list of 10 drugs whose new prices were announced Thursday under Medicare's drug price negotiation program. The price negotiation program was passed in 2022 as part.

Medicare 142

Medicare 142

Becker's Hospital Review - Cardiology

AUGUST 14, 2024

Boise, Idaho-based St. Luke's Regional Medical Center has the lowest readmission rate for heart failure patients, CMS found.

Heart Failure 116

Heart Failure CMS Hospital 116

Dr. Smith's ECG Blog

AUGUST 26, 2024

A 60-something woman with no cardiac history presented with epigastric and right upper quadrant pain after eating spicy food. She had an ECG recorded at triage: What do you think? This was sent to me without any info while I was out and about, and I looked at it on my phone. I responded: "That is a tough one. V2 is very worrisome. But no other leads are.

Myocardial Infarction 114

Myocardial Infarction Critical Care Echocardiogram Ischemia 114

HCPLive

AUGUST 1, 2024

An analysis of more than 11,000 people with T1D found people were more likely to report an affected father than an affected mother.

Diabetes 124

Diabetes 124

Science Daily - Heart Disease

AUGUST 12, 2024

Patients with a common heart arrhythmia called Atrial Fibrillation could benefit from future treatments that target inefficiencies in heart cell metabolism, according to a new article.

Arrhythmia 114

Arrhythmia Atrial Fibrillation Article 114

Dr. Paddy Barrett

AUGUST 23, 2024

High levels of fitness are arguably the best predictors of longevity. If you want to extend your lifespan, prioritising fitness is essential. If you are not prioritising fitness, then you are leaving huge potential gains on the table. Here’s why. The evidence that high levels of exercise and subsequent fitness are linked with increased lifespan and health span is clear.

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Exercise Dementia Cancer Chronic Disease 112

Med Page Today

AUGUST 12, 2024

(MedPage Today) -- An anti-inflammatory diet was tied to a lower risk for dementia in people ages 60 and older with cardiometabolic diseases, U.K. Biobank data showed. Among people with cardiometabolic diseases including type 2 diabetes, heart.

Dementia 137

Dementia Diet Diabetes 137