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Objective To use echocardiographic and clinical features to develop an explainable clinical risk prediction model in patients with aortic stenosis (AS), including those with low-gradient AS (LGAS), using machine learning (ML). Methods In 1130 patients with moderate or severe AS, we used bootstrap lasso regression (BLR), an ML method, to identify echocardiographic and clinical features important for predicting the combined outcome of all-cause mortality or aortic valve replacement (AVR) within 5
Due to the continuous development of medicine and the huge amount of clinical data collected while practicing it, there is an urgent need to optimize the working time of clinicians. One way to do this is to analyze clinical data using machine learning and artificial intelligence (AI) based on predictive models. These models predict the presence or future occurrence of specific outcomes (e.g., a specific condition or disease) with specific inputs (e.g., certain patient characteristics or medical
Is 15 lead ECG better than 12 lead for diagnosing posterior MI or right ventricular infarction? When do you need a 15 lead ECG? Jesse McLaren guides us through 8 cases to highlight the steps and pitfalls in diagnosing posterior MI and RVMI in light of recent ECG literature. The post ECG Cases 31 Is a 15 lead ECG better than 12? Diagnosing Posterior MI and RVMI appeared first on Emergency Medicine Cases.
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
A 30-something male presented in the middle of the night with several hours of sharp, non-radiating, left sided chest pain. It was there earlier, went away, and then returned approximately 1 hour prior to arrival. He is a smoker and has some family history of early MI. Exam and vital signs were normal. Here was the triage ECG: There appears to be diffuse ST Elevation (II, III, aVF with reciprocal STD in aVL, V3-V6, and lead I, with T-waves that appear to be hyperacute (broad and fat, but on the
David Didlake Firefighter / Paramedic Acute Care Nurse Practitioner @DidlakeDW Peer review and commentary by Dr. Steve Smith [link] @SmithECGblog It is early-summer, approximately 1330 hours, no cloud cover overhead, and 86 degrees with high humidity. A 59 y/o Female calls 911 for crushing chest discomfort and difficulty breathing. Fire/EMS personnel find her laying supine on the kitchen floor, awake and verbal, although acutely ill.
Background Hepatocyte growth factor (HGF) is a biomarker with potential for use in the diagnosis, treatment and prognostication of cardiovascular disease (CVD). Elevated HGF is associated with calcification in the coronary arteries. However, knowledge is limited on the role HGF may play in extracoronary calcification (ECC). This study examined whether HGF is associated with ECC in the aortic valve (AVC), mitral annulus (MAC), ascending thoracic aorta and descending thoracic aortic (DTAC).
Background Hepatocyte growth factor (HGF) is a biomarker with potential for use in the diagnosis, treatment and prognostication of cardiovascular disease (CVD). Elevated HGF is associated with calcification in the coronary arteries. However, knowledge is limited on the role HGF may play in extracoronary calcification (ECC). This study examined whether HGF is associated with ECC in the aortic valve (AVC), mitral annulus (MAC), ascending thoracic aorta and descending thoracic aortic (DTAC).
Cardiologists are required to complete recertification as part of their requirements to remain a practicing physician. The Cardiovascular Disease Maintenance of Certification Exam can be difficult, with a pass rate in 2021 of 88%. What are some things you need to know before you sit for the exam? Here are some common questions surrounding the Cardiology MOC Exam: When is the Cardiology MOC exam offered?
A 55 years old diabetic male patient who had 12 stents in his heart underwent a successful beating heart bypass surgery under Dr. Prateek Bhatnagar, Director Cardiac Surgery. The patient was suffering with angina (chest pain) since 2002. He received these 12 stents on 5 different occasions at 5 different hospitals of the twin cities. The last 3 stents were placed just 6 months back but were not working.
In this first part of our 2-part series on Cardiac Arrest Controversies Rob Simard, Bourke Tillman, Sara Gray and Scott Weingart discuss with Anton how best to ensure high quality chest compressions, the pros and cons of mechanical CPR, the literature on dual sequential defibrillation and optimizing pad placement, epinephrine vs vasopressin, amiodarone vs lidocaine, when to consider IV calcium and sodium bicarbonate, esmolol, airway considerations, sedation in cardiac arrest, the pros and cons o
Written by Pendell Meyers, edits by Smith and Grauer A man in his late 20s with history of asthma presented to the ED with a transient episode of chest pain and shortness of breath after finishing a 4-mile run. He typically runs 4 to 8 miles per day. This episode was unusual to him because he was still "huffing and puffing" about 30 minutes after finishing his strenuous run in the outdoor heat.
KING'S College London has performed an essential function in current years in assisting the sector to apprehend the converting nature of COVID-19. It is way to their efforts that scientists have been capable of the song the converting signs of Covid, and the way its miles affect the human body. Now studies from the University are asking at converting the manner coronary heart assaults are treated.
Aims This study aims to (1) define the characteristics of patients with a first admission for heart failure (HF), stratified by type (reduced (HFrEF) vs preserved (HFpEF) ejection fraction) in a regional Australian setting; (2) compare the outcomes in terms of mortality and rehospitalisation and (3) assess adherence to the treatment guidelines. Methods We identified all index hospitalisations with HF to John Hunter Hospital and Tamworth Rural Referral Hospital in the Hunter New England Local Hea
David Didlake Firefighter / Paramedic Acute Care Nurse Practitioner @DidlakeDW Peer review provided by Dr. Steve Smith [link] @SmithECGBlog An adult female called 911 for chest discomfort and difficulty breathing. EMS found her acutely ill, mottled, dry mucous membranes, modestly hypotensive, and lethargic. She reported a history of IDDM, but denied any known ischemic heart disease.
This cohort study conducted using nationwide registers assesses the risks of myocarditis and pericarditis after SARS-CoV-2 messenger RNA vaccinations in a combined population of 23.1 million individuals across Denmark, Finland, Norway, and Sweden.
On this month's EM Quick Hits: Christina Shenvi on ACS in older people, Nour Khatib on rural NRP, Jess McLaren on how not to get fooled by ECG computer interpretation, Brit Long on hemophilia recognition and workup, Maria Ivankovic on persistent and intractable hiccups from EM Cases Summit 2021. The post EM Quick Hits 38 ACS in Older Patients, Rural Neonatal Resuscitation, Hemophilia, Hiccups, ECG Computer Interpretation appeared first on Emergency Medicine Cases.
A 30-something male without any significant past medical history presented with palpitations and presyncope. Here is his ED ECG: Regular Wide Complex Tachycardia at a rate of 229 First : What do you want to do? Next : What do you think is the ECG diagnosis? First. Before getting into analysis, a regular wide complex tachycardia could be 1. ventricular tachycardia ( VT ) or 2.
Avocados incorporate a massive quantity of fat. Despite this, including them to a person’s food regimen can assist raise “suitable” ldl cholesterol degrees. However, they'll now no longer assist decrease “awful” ldl cholesterol with out extra food regimen changes. Adding avocados to a person’s food regimen could have high quality fitness benefits, such as elevating degrees of high-density lipoprotein (HDL) ldl cholesterol, frequently known as suitable ldl cholesterol.
Objectives Although cardiovascular magnetic resonance (CMR) is increasingly used to diagnose pericardial inflammation, imaging can still be challenging using conventional CMR techniques. Parametric mapping (T1/T2 mapping) techniques have emerged as novel methods to quantify focal and global changes of the myocardium without contrast agent. The aim of the present study was to implement parametric mapping to facilitate diagnostic decision-making in pericardial inflammation.
This meta-analysis of patients with out-of-hospital cardiac arrest assesses the long-term survival rate in those who survive the initial hospital stay.
You can download this script as a Hindi translation here. Today’s vlog is on the subject of heart failure and in particular on a special type of pacemaker which can make a significant improvement to the quality of life and length of life in patients with heart failure. What is heart failure? The heart is a pump and if the heart is in some way damaged – be that by a heart attack or a virus or harmful drugs then the heart is unable to pump out enough blood to meet the body’s requirements esp
Submitted and written by Destiny Folk MD , peer reviewed by Meyers, Smith, Grauer, McLaren A man in his early 30s with no significant past medical history was brought to the ED by EMS after being found unresponsive by a friend. EMS arrived and found him awake and alert. He complained of generalized weakness and left lower extremity numbness. He reported that 12 hours prior to arrival he used fentanyl and cocaine.
Often whilst a person is stimulated to lose weight, they are determined to begin doing extra at-domestic aerobic workouts. When a person’s stimulated to do extra at-domestic aerobic workouts, they typically purchase a bit of steeply-priced exercise equipment. And after they get uninterested in the steeply-priced exercise equipment, it finally ends up serving often as an apparel rack.
Objective To determine the impact of sodium-dependent glucose type 2 cotransporter inhibitors on the renal function in acute heart failure. Methods In a single-centre, controlled, randomised study, patients were prescribed dapagliflozin in addition to standard therapy, or were in receipt of standard therapy. The prespecified outcome was renal function deterioration; the secondary outcomes were the development of resistance to diuretics, weight loss, death during hospitalisation and the rehospita
A cardiac arrhythmia is an abnormal heartbeat caused by a problem in the "wiring" of your heart muscle. You may or may not feel it but it should not be ignored.
Atrial fibrillation, the most common cardiac rhythm abnormality, has been linked to one-third of ischemic strokes, the most common type of stroke. But atrial fibrillation is underdiagnosed, partly because many patients are asymptomatic.
Written by Jesse McLaren, with comments by Smith and Grauer Four patients presented with cardiorespiratory symptoms, with inferior ST elevation and reciprocal change on their ECG. Which patient had occlusion MI? Note: according to the STEMI paradigm these ECGs are easy, but in reality they are difficult. First lets start with each ECG without clinical context.
A vascular closure tool (VCD) is a clinical tool used to prevent bleeding after puncturing the femoral artery for the duration of diagnostic angiography or interventional procedures. VCDs are an opportunity to guide compression due to the fact they are able to right away seal the access web website online of the femoral artery. Since St. Jude Medical, Inc. obtained popularity of VasoSeal device in 1995, VCD has been advertised withinside the U.S.
Background The clinical significance of peak troponin levels following ST-elevation myocardial infarction (STEMI) has not been definitively established. The purpose of this study was to examine the relationship between peak high-sensitivity cardiac troponin T (hs-cTnT) and all-cause mortality at 30 days and 1 year, and left ventricular ejection fraction (LVEF) in STEMI.
Objective Heart failure following allogeneic haematopoietic stem cell transplantation (allo-HSCT) is a serious complication that requires early detection; however, the clinical implications of early-onset cancer therapy-related cardiac dysfunction (CTRCD) following allo-HSCT remain unclear. We investigated the determinants and prognostic impact of early-onset CTRCD in allo-HSCT recipients.
Objective The study evaluated the feasibility of mindfulness-based cognitive therapy (MBCT) in patients with non-cardiac chest pain by assessing their willingness to participate and adhere to the programme, and for these data to help further refine the content of MBCT for chest pain. Patients and methods This prospective 2:1 randomised controlled trial compared the intervention of adapted MBCT as an addition to usual care with just usual care in controls.
Background The diagnosis of infective endocarditis (IE) is based on the modified Duke/European Society of Cardiology (ESC) 2015 clinical criteria. The sensitivity of the criteria is unknown in South Africa, but high rates of blood culture negative endocarditis (BCNIE), coupled with a change in the clinical features of IE, may limit the sensitivity. Methods The Tygerberg Endocarditis Cohort study prospectively enrolled patients with IE between November 2019 and June 2021.
Objective To identify the most common transthoracic echocardiogram (TTE) parameters in patients hospitalised with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2/COVID-19) and their association with myocardial injury and outcomes. Methods A retrospective, single-centre, observational, exploratory cohort study was performed at the height of the COVID-19 pandemic.
Background Despite rapid technological advances and growth, quality in imaging has not received the focus seen elsewhere in cardiovascular medicine, resulting in significant gaps between guidelines and practice. Contemporary echocardiography practice requires comprehensive real-time data collection to allow dynamic auditing and benchmarking of key performance indices.
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