Wed.Feb 14, 2024

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Menopause and migraines: New findings point to power of prevention

Science Daily - Heart Disease

Women who have both migraines and a long-term history of hot flashes and/or night sweats have a slightly higher risk of heart disease and stroke, and young women who have migraines have a higher risk of later persistent menopause symptoms, according to two new papers based on a data from a long-term study of the same group of women from their young adult to middle-age years.

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AI Measures Fat Around the Heart, a Key to Predicting Heart Attacks

DAIC

milla1cf Wed, 02/14/2024 - 18:21 February 14, 2024 — Efemoral Medical , developer of advanced interventional bioresorbable therapies, today announced that the United States Food & Drug Administration ( FDA ) has granted its novel Efemoral Vascular Scaffold System (EVSS) Breakthrough Device status for the treatment of de novo or restenotic lesions of the infrapopliteal arteries in patients with Chronic Limb Threatening Ischemia (CLTI).

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Targeting the microenvironment rather than a specific cell type could be the key to healing injured hearts

Science Daily - Heart Disease

A groundbreaking scientific study has unveiled a remarkable discovery that may have far-reaching implications for the treatment of heart disease. The implications are immense offering glimpses of a future where heart disease may no longer be an irreversible condition but a challenge that can be overcome through medical intervention. The potential for developing novel therapies that leverage the body's innate regenerative capacity holds great promise for millions of individuals affected by heart

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First-of-its-kind ACC Registry Tracks Cardiac Procedures Performed in Ambulatory Surgical Settings

DAIC

milla1cf Wed, 02/14/2024 - 18:53 February 14, 2024 — The American College of Cardiology ’s newest registry offers data-driven insights on cardiac procedures performed in the ambulatory surgery setting through its first-of-its-kind dashboard. The number of cardiac procedures being performed in ambulatory surgery centers has grown significantly in the last decade, leading ACC’s NCDR to create the CV ASC Registry Suite to fit into the established workflow and allow these facilities to measure and

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Association of plasma angiogenin with risk of major cardiovascular events in type 2 diabetes

Cardiovascular Diabetology

Angiogenin, an enzyme belonging to the ribonucleases A superfamily, plays an important role in vascular biology. Here, we sought to study the association of plasma angiogenin and major adverse cardiovascular e.

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DECIDE-Salt Study Finds Salt Substitutes Help to Maintain Healthy Blood Pressure in Older Adults

DAIC

The replacement of regular salt with a salt substitute can reduce incidences of hypertension, or high blood pressure, in older adults without increasing their risk of low blood pressure episodes, according to a study published in the Feb. 2024 issue of the Journal of the American College of Cardiology (JACC). Image courtesy: Getty Images christine.book Wed, 02/14/2024 - 09:54 February 14, 2024 — The replacement of regular salt with a salt substitute can reduce incidences of hypertension, or hig

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Obesity Linked to Increased Disease Activity in ACPA-Positive Rheumatoid Arthritis

HCPLive

Patients with ACPA-positive RA and obesity had greater DAS44 scores compared to normal-weight patients, although this difference was not present in ACPA-negative RA.

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Rheumatoid Arthritis with Depression Puts Patients at Greater Risk of Mortality

HCPLive

Patients with both rheumatoid arthritis and depression have an increased risk of mortality by more than 2 times than patients with RA but no depression, according to a new study.

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Genetic study clarifies the link between birth weight and adult morbidity

Medical Xpress - Cardiology

A unique Finnish study has investigated the link between growth conditions in the womb and cardiovascular disease in adulthood. The results highlight the importance of shared genetic factors between mother and child.

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Various Inflammatory Cytokines Related to Etiology of Inflammatory Arthritis

HCPLive

A Mendelian randomization analysis provided new insights into the relationship between inflammatory cytokines and ankylosing spondylitis, rheumatoid arthritis, and psoriatic arthritis.

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Faster brain hemorrhage treatment increases survival odds, new study finds

Medical Xpress - Cardiology

Taking an anticoagulant, or blood-thinning medication, can increase one's risk of—or exacerbate—a brain bleed, also known as a brain hemorrhage, which is the deadliest type of stroke. Now, new research finds that faster treatment for these patients is associated with a greater likelihood of survival.

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FDA Approves Iloprost Injection for Treatment of Severe Frostbite

HCPLive

The approval provides patients with the first-ever treatment option for severe frostbite to prevent the amputation of fingers or toes.

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Little by little: How small changes can lead to heart health

Medical Xpress - Cardiology

Switching from an unhealthy diet and sedentary lifestyle to healthy eating and exercise can be daunting. In this expert alert, Juan Cardenas Rosales, M.D., an internal medicine physician and medical director of the international medicine practice at Mayo Clinic in Jacksonville, Florida, shares small steps and one big one that can lead to a heart-healthy life.

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Upadacitinib Improves Enthesitis Among Patients with Psoriatic Arthritis

HCPLive

The findings of this post-hoc analysis suggest a need for follow-up studies assessing and comparing JAK inhibition impact on the development of enthesitis.

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A new test could predict how heart attack patients will respond to mechanical pumps

Science Daily - Heart Disease

Researchers discovered why ventricular assist devices (VADs) used to support the left ventricle of cardiogenic shock patients can induce right ventricle dysfunction. They also developed a test that doctors could use to determine whether this dysfunction will occur.

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Genetic keys to cardiovascular health: A study from Mexico City

Medical Xpress - Cardiology

In Mexico City, researchers at the Instituto Nacional de Cardiología Ignacio Chávez have studied genetic underpinnings of one of the most pressing public health challenges of our times: cardiovascular disease (CVD).

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Combination of early rhythm control and healthy lifestyle on the risk of stroke in elderly patients with new-onset atrial fibrillation: a nationwide population-based cohort study

Frontiers in Cardiovascular Medicine

Background The impact of early rhythm control (ERC) combined with healthy lifestyle (HLS) on the risk of ischemic stroke in elderly patients with atrial fibrillation (AF) remains unaddressed. Objective To evaluate the impact of combined ERC and HLS on the risk of stroke in elderly patients with new-onset AF. Methods Using the Korean National Health Insurance Service database, we included patients aged ≥75 years with new-onset AF from January 2009 to December 2016 ( n  = 41,315).

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Efficacy of Left Bundle Branch Area Pacing Versus Biventricular Pacing in Cardiac Resynchronization Therapy Patients: Select Site - Cohort Study

HeartRhythm

Cardiac resynchronization therapy (CRT) is typically attempted with biventricular pacing. One-third of patients are non-responders. Left bundle branch area pacing (LBBAP) has been evaluated as an alternative means.

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Primary Spontaneous Pneumothorax

The New England Journal of Medicine

This feature about a man who has had a spontaneous pneumothorax offers a case vignette accompanied by two essays, one supporting insertion of a chest tube and the other recommending following the patient closely as an outpatient.

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A new test could predict how heart attack patients will respond to mechanical pumps

Medical Xpress - Cardiology

Every year, around 50,000 people in the United States experience cardiogenic shock—a life-threatening condition, usually caused by a severe heart attack, in which the heart can't pump enough blood for the body's needs.

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Role of Cognitive Frailty in Older Adults With Cardiovascular Disease

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. As the older adult population expands, an increasing number of patients affected by geriatric syndromes are seen by cardiovascular clinicians. One such syndrome that has been associated with poor outcomes is cognitive frailty: the simultaneous presence of cognitive impairment, without evidence of dementia, and physical frailty, which results in decreased cognitive reserve.

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In Rheumatic Disease, Cardiovascular Risk Peaks Within Year of Diagnosis

HCPLive

A Finnish study finds elevated cardiovascular risk in rheumatic diseases peaks within a year of diagnosis, emphasizing the need for early management strategies.

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Atrial Cardiopathy and Antithrombotic Drugs in Prevention After Cryptogenic Stroke

American College of Cardiology

The goal of the ARCADIA trial was to determine whether apixaban reduces the risk of recurrent stroke compared with placebo in patients with cryptogenic ischemic stroke and evidence of atrial cardiopathy but without atrial fibrillation (AF).

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Patient-centered evaluation of an expectation-focused intervention for patients undergoing heart valve surgery: a qualitative study

Frontiers in Cardiovascular Medicine

Objective Randomized controlled trials demonstrate the effectiveness of expectation-focused interventions in improving recovery outcomes following cardiac surgery. For dissemination in routine health care, it is important to capture the perspective of affected individuals. This qualitative study explores the perceived benefits and intervention-specific needs of patients who received expectation-focused intervention in the context of heart valve surgery.

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FDA Advisors Nearly All Aboard the TriClip Train for Tricuspid Regurgitation

Med Page Today

(MedPage Today) -- FDA advisors were nearly unanimous in backing the TriClip G4 transcatheter edge-to-edge repair (TEER) device as a treatment for severe tricuspid regurgitation (TR). During an advisory committee meeting on Tuesday, the FDA's.

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Case Report: Resuscitation of patient with tumor-induced acute pulmonary embolism by venoarterial extracorporeal membrane oxygenation

Frontiers in Cardiovascular Medicine

Background Pulmonary embolism is a condition of right cardiac dysfunction due to pulmonary circulation obstruction. Malignant tumor-induced pulmonary embolism, which has a poor therapeutic outcome and a significant impact on hemodynamics, is the cause of sudden death in patients with malignant tumors. Case description A 38-year-old female patient, who had a medical history of right renal hamartoma, and right renal space-occupying lesion, was admitted to the hospital.

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The Association of Type 2 Diabetes Mellitus and Hyperglycemia With Subclinical Atherosclerosis in South Asian Adults

American College of Cardiology

The risk of atherosclerotic cardiovascular disease (ASCVD) is approximately twofold higher for South Asian (SA) adults than for adults from other racial and ethnic groups. Type 2 diabetes mellitus (T2DM) is a highly prevalent risk factor that likely contributes to this disparity.

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Higher Vitamin D Levels Pre-Methotrexate Linked to Lower Mortality in RA

HCPLive

After adjusting for risk factors, patients in the > 50 nmol/L pre-methotrexate initiation group exhibited a 28% reduced risk of mortality when compared with those in the ≤ 50 nmol/L group

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FDA Panel Strongly Supports Abbott TriClip TEER

CardiacWire

The FDA expert advisory panel votes are in , and they’re pointing in an overwhelmingly positive direction for Abbott’s TriClip tricuspid edge-to-edge repair (TEER) treatment. The TriClip G4 is intended to treat tricuspid regurgitation by clipping together a portion of a patient’s tricuspid valve leaflets to keep blood from leaking from the right ventricle into the atrium.

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Accelerated Aging Linked to Greater Risk of Rheumatoid Arthritis

HCPLive

In a new study, cross-sectional analyses showed each 1-year increase in age-adjusted biological age was linked to a 1% - 10% increase in the risk of rheumatoid arthritis.

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Device-Measured Physical Activity and Cardiometabolic Health

American College of Cardiology

What is the impact of reallocating time from one movement behavior (sleep, sedentary behavior [SB], standing, low-intensity physical activity [LIPA], moderate–vigorous physical activity [MVPA]) to another on cardiometabolic risk factors?

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FDA Panel Votes in Favor of Abbott TriClip for Tricuspid Regurgitation

HCPLive

FDA advisory committee votes 13-1 that the benefits outweigh the risk of use for Abbott's TriClip for tricuspid regurgitation, pending FDA decision expected in 2024.

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The effect of ulinastatin on acute kidney injury in patients undergoing off-pump cardiac bypass surgery

Journal of Cardiothoracic Surgery

Ulinastatin, an anti-inflammatory and antioxidant trypsin inhibitor, has shown potential in mitigating acute kidney injury (AKI) and reducing serum creatinine levels after various surgeries. This retrospective.

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Biologics License Application for Nemolizumab Accepted by FDA for Prurigo Nodularis, Atopic Dermatitis

HCPLive

In addition to the newly-accepted BLA in the US, the European Medicines Agency also accepted the drug’s Marketing Authorization Application for both conditions.

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Efficacy and safety of enavogliflozin vs. dapagliflozin as add-on therapy in patients with type 2 diabetes mellitus based on renal function: a pooled analysis of two randomized controlled trials

Cardiovascular Diabetology

We assessed the efficacy and safety of enavogliflozin (0.3 mg), a newly developed SGLT-2 inhibitor, in patients with type 2 diabetes mellitus based on kidney function via pooled analysis of two 24-week, random.

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Role of Left Ventricular Ejection Fraction in Modern High-Risk PCI with pLVAD Support

Cardiology Update

In the early years of percutaneous coronary intervention (PCI), studies indicated a heightened risk of major adverse cardiac events (MACE) in patients with reduced left ventricular ejection fraction (LVEF), involving outcomes such as death, Q-wave myocardial infarction (MI), stent thrombosis, and repeat revascularization. Patients with LV systolic dysfunction often present with multiple comorbidities and complex coronary artery disease (CAD), leading to a greater myocardial jeopardy and increase

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The effectiveness of sodium-glucose co-transporter 2 inhibitors on cardiorenal outcomes: an updated systematic review and meta-analysis

Cardiovascular Diabetology

The 2022 Canadian Cardiovascular Society (CCS) cardiorenal guideline provided clinical recommendations on sodium-glucose co-transport 2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP-1R.