Mon.May 06, 2024

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Dementia Mortality Tied to Olive Oil Consumption

Med Page Today

(MedPage Today) -- Higher olive oil intake was associated with a lower risk of dementia-related mortality, a prospective study of 90,000 healthcare professionals showed. Eating at least 7 g of olive oil daily -- about a half tablespoon --.

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Clinical Quiz: Lp(a) Treatments and Therapeutics Considerations

HCPLive

The final in our 3-part quiz series based on the NLA's 2024 update to their 2019 scientific statement on use of lipoprotein(a) in clinical practice focuses on treatment considerations and therapeutic options for elevated Lp(a).

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Kids With Hypertension May Have Twice the Risk of Cardiac Events

Med Page Today

(MedPage Today) -- Children diagnosed with hypertension had a higher associated long-term risk of major adverse cardiac events (MACE) compared with matched controls without the condition, according to a Canadian population-based, retrospective.

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Paul Appelbaum, MD: What to Warn Patients When Prescribing Psychedelics in the Future

HCPLive

In an interview, Paul Appelbaum, MD, discussed issues clinicians will need to bring up to their patients if the FDA approves a psychedelic-assisted therapy.

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Tenax Therapeutics Announces New U.S. Patent Covering the Use of Levosimendan in Pulmonary Hypertension with Heart Failure with Preserved Ejection Fraction (PH-HFpEF)

DAIC

Getty Images milla1cf Mon, 05/06/2024 - 10:48 May 6, 2024 — Tenax Therapeutics, Inc. , a Phase 3, development-stage pharmaceutical company focused on identifying, developing and commercializing products that address cardiovascular and pulmonary diseases with high unmet medical need, announced that the United States Patent and Trademark Office ( USPTO ) has granted the Company a patent covering the use of TNX-103 (oral l evosimendan ), TNX-102 (subcutaneous levosimendan), TNX-101 (IV levosimendan

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FDA Advisory Committee Meeting to Review MDMA-Assisted Therapy for PTSD

HCPLive

Lykos Therapeutics' new drug application for MDMA plus psychiatric intervention for adults with PTSD will be the first reviewed by an FDA committee for such a therapy.

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Teleflex Announces the Limited Market Release of the Wattson Temporary Pacing Guidewire

DAIC

milla1cf Mon, 05/06/2024 - 10:50 May 6, 2024 — Teleflex Incorporate , a leading global provider of medical technologies, today announced that the Wattson Temporary Pacing Guidewire limited market release has commenced at Columbia University Irving Medical Center. The first cases were performed by Dr. Tamim Nazif , Director of Clinical Research, Dr. Susheel Kodali , Professor of Medicine and Director of the Structural Heart and Valve Center , and Dr.

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SMT and HeartX Forge Transformative Partnership in Cardiovascular Space

DAIC

milla1cf Mon, 05/06/2024 - 10:55 May 6, 2024 — SMT (Sahajanand Medical Technologies), a leading medical device company at the forefront of innovative patient care in the cardiovascular segment has announced a strategic partnership with HeartX , a pioneering MedTech company focused on research and development. Through this collaboration, SMT gains an innovative product line in the Congenital Heart Defect space.

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With Help From AI, Randy Travis Got His Voice Back After Debilitating Stroke

Med Page Today

(MedPage Today) -- With some help from artificial intelligence (AI), country music star Randy Travis, celebrated for his timeless hits like "Forever and Ever, Amen" and "I Told You So," has his voice back. In July 2013, Travis was hospitalized.

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Large registry data demonstrate PCI for stable CAD can be safely performed before, during or after TAVR

Medical Xpress - Cardiology

New data reveal that percutaneous coronary intervention (PCI) can be safely performed before, during, or after transcatheter aortic valve replacement (TAVR) for patients with stable coronary artery disease (CAD). The results from the analysis were presented at the Society for Cardiovascular Angiography & Interventions (SCAI) 2024 Scientific Sessions.

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Vitamin D May Modulate Immune Function in Chronic HBV Infection

HCPLive

Vitamin D concentration was significant in chronic hepatitis B virus but not hepatitis C virus infection, suggesting its potential impact on immune response.

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SGLT1 and SGLT2 inhibition, circulating metabolites, and cerebral small vessel disease: a mediation Mendelian Randomization study

Cardiovascular Diabetology

Sodium-glucose cotransporter 2 (SGLT2) and SGLT1 inhibitors may have additional beneficial metabolic effects on circulating metabolites beyond glucose regulation, which could contribute to a reduction in the b.

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Illusion of revascularization: does anyone achieve optimal revascularization during percutaneous coronary intervention?

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 07 May 2024; doi:10.1038/s41569-024-01014-0 In 1993, Lincoff and Topol claimed that the thrombolytic treatment of ST-segment elevation myocardial infarction was suboptimal in many patients and gave an ‘illusion of reperfusion’. In this Perspective article, the authors propose that a similar illusion of revascularization exists for contemporary percutaneous revascularization in patients with coronary artery disease and ischaemia, and identify how outco

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Discussing the Potential Approval of Tapinarof for Atopic Dermatitis with John Browning, MD

HCPLive

In this interview, Browning discusses his team’s trial data and the implications of the FDA’s decision to accept the supplemental new drug application for tapinarof as an eczema treatment.

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Reduced Ejection Fraction in Elite Endurance Athletes

American College of Cardiology

What is the prevalence, what is the genetic predisposition, and what are the clinical consequences of reduced left (LVEF) and/or right ventricular ejection fraction (RVEF) among endurance athletes?

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Diabetes and aortic dissection: unraveling the role of 3-hydroxybutyrate through mendelian randomization

Cardiovascular Diabetology

In observational and experimental studies, diabetes has been reported as a protective factor for aortic dissection. 3-Hydroxybutyrate, a key constituent of ketone bodies, has been found to favor improvements i.

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AI an Effective Geographic Atrophy Screening Tool

HCPLive

Retina specialists and an AI screening tool trained to measure geographic atrophy agreed in a majority of cases, potentially expediting clinical trial enrollment and increasing consistency in measuring the disease.

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HA’s Top 10 Takeaways for Healthcare HR Professionals | ASHHRA ’24

Learning + Leading

If you’re a healthcare human resources professional and missed this year’s fantastic ASHHRA conference in Fort Worth, TX , a few weeks ago we’ve got you covered! We know you’re searching for cutting-edge healthcare HR staffing solutions that will give you the skills insights you need to build smarter training programs. That’s why NHA was there to showcase our variety of healthcare employer staffing solutions.

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HORNBILL: BI 764524 Meets Safety Endpoints in Diabetic Macular Ischemia

HCPLive

BI 764524 was well tolerated following intravitreal administration of single and multiple doses in the phase 1/2a trial, with signs pointing to early efficacy.

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ATTR-ACT Post Hoc Analysis: AFib/AFL Not Predictive of Mortality in Patients With ATTR-CM

American College of Cardiology

Although atrial fibrillation/atrial flutter (AFib/AFL) are common manifestations of transthyretin amyloid cardiomyopathy (ATTR-CM), a post hoc analysis of the ATTR-ACT study, published April 30 in JACC: CardioOncology, found they do not predict all-cause mortality. Furthermore, baseline or historical AFib/AFL did not impact the efficacy of treatment with tafamidis.

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Ashkan M. Abbey, MD: 3-Year Efficacy of Pegcetacoplan for Geographic Atrophy

HCPLive

At ARVO 2024, Ashkan Abbey, MD describes key data from the pivotal OAKS and DERBY, and the GALE extension trial over 3 years of pegcetacoplan treatment.

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Impact of acute glycemic variability on short-term outcomes in patients with ST-segment elevation myocardial infarction: a multicenter population-based study

Cardiovascular Diabetology

Given the increasing attention to glycemic variability (GV) and its potential implications for cardiovascular outcomes. This study aimed to explore the impact of acute GV on short-term outcomes in Chinese pati.

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Whole exome sequencing and proteomics-based investigation of the pathogenesis of coronary artery disease with diffuse long lesion

Journal of Cardiothoracic Surgery

The long-term prognosis of patients with coronary artery disease (CAD) with diffuse long lesion underwent coronary artery bypass graft (CABG) or percutaneous coronary intervention (PCI) remains worse. Here, we.

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Joint association of TyG index and high sensitivity C-reactive protein with cardiovascular disease: a national cohort study

Cardiovascular Diabetology

Both the triglyceride-glucose (TyG) index, as a surrogate marker of insulin resistance, and systemic inflammation are predictors of cardiovascular diseases; however, little is known about the coexposures and r.

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Anomalous circumflex artery encircling the aortic annulus: implications for mitral valve repair

Journal of Cardiothoracic Surgery

Injury to coronary arteries during mitral surgery is a rare but life-threatening procedural complication, an anomalous origin and course of the left circumflex artery (LCx) increase this risk. Recognizing the.

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Cross-sectional and longitudinal associations of Iron biomarkers and cardiovascular risk factors in pre- and postmenopausal women: leveraging repeated measurements to address natural variability

Cardiovascular Diabetology

The association between iron biomarkers and cardiovascular disease risk factors (CVD-RFs) remains unclear. We aimed to (1) evaluate the cross-sectional and longitudinal associations between iron biomarkers (se.

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Case Report: Three cases of clinically suspected viral myocarditis with recovery of left ventricular dysfunction

Frontiers in Cardiovascular Medicine

Viral myocarditis is an important cause of non-ischemic cardiomyopathy. Multiple clinical manifestations have been reported, including acute heart failure, cardiogenic shock, and ventricular arrhythmias. We present three patients with clinically suspected viral myocarditis causing acute heart failure. Serum coxsackievirus B antibodies were positive in all three patients.

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Risk for 'most' cardiovascular diseases no higher with inflammatory bowel disease, study finds

Medical Xpress - Cardiology

Among postmenopausal women with inflammatory bowel disease (IBD), there is no higher risk for cardiovascular disease (CVD) compared with women without IBD, although the risk for ischemic stroke may be higher, according to a study published online April 29 in Digestive Diseases and Sciences.

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Imaging-Only Diagnosis of Giant Cell Arteritis Is Feasible

Med Page Today

(MedPage Today) -- Positive findings with color Doppler ultrasound were enough to diagnose giant cell arteritis (GCA) accurately without need for confirmation with temporal artery biopsy (TAB), a prospective study indicated. Out of 165 older patients.

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Personalized screening early in pregnancy may improve preeclampsia detection

Medical Xpress - Cardiology

A new screening algorithm for preeclampsia combining maternal history, ultrasound data and several tests for blood markers may better predict the majority of preeclampsia cases in the first trimester of pregnancy, when it may still be preventable, according to new research published in Hypertension.

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Patient Subgroups With a Higher Prevalence of Hypercortisolism

HCPLive

The panel emphasizes the importance of early identification of patients based on subgroups, such as those with difficult-to-control diabetes, hypertension, and bone issues, highlighting that the inability to lower a patient's insulin dosage is a significant risk factor for hypercortisolism.

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Reviewing the Ross Procedure with Dr. Kerendi

CTVS

The Ross procedure is a complex operation designed to replace a diseased or damaged aortic valve. This unique surgery relies on a patient’s own existing tissue, the pulmonary valve, to replace the aortic valve rather than using an artificial valve.

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Testing for Hypercortisolism

HCPLive

Christopher Lucci, MD, reviews the current diagnostic tests for hypercortisolism, which include the Dexamethasone Suppression Test, DHEA level tests, and ACTH assessments.

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Smoking Cessation Strategies After Initial Treatment Failure

American College of Cardiology

Does treatment with varenicline or combined nicotine replacement therapy (CNRT) improve smoking cessation rates among smokers who do not quit on their initial attempt?

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Study Highlights Evidence Gaps in IgA Nephropathy Disease Burden, Treatment Patterns

HCPLive

Results showed the prevalence and treatment patterns for IgAN in select Asian Pacific countries and regions were not commonly available.

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ACC CardiaCast: Exploring HF&T Highlights from ACC.24: RELIEVE-HF, REDUCE AMI, and DANGER-Shock Trials

American College of Cardiology

Dive into the Heart of ACC.24's Heart Failure and Transplant Highlights! In this podcast, Drs. Maya Guglin, Shelley Hall, Onyedika Ilonze, and Kazuhiko Kido dissect the most captivating advancements and groundbreaking revelations from the ACC.24 sessions in heart failure and transplant, including trials RELIEVE-HF, REDUCE-AMI, and DanGer Shock.

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Causal Relationship Observed Between Angina Pectoris and Gout Onset

HCPLive

The meta-analysis demonstrated gout with high blood uric acid levels significantly increases the risk of experiencing angina attacks.

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