Mon.May 06, 2024

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Dementia Mortality Tied to Olive Oil Consumption

Med Page Today

(MedPage Today) -- Higher olive oil intake was associated with a lower risk of dementia-related mortality, a prospective study of 90,000 healthcare professionals showed. Eating at least 7 g of olive oil daily -- about a half tablespoon --.

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New study reveals age-related brain changes influence recovery after stroke

Science Daily - Stroke

A new study has revealed that areas of age-related damage in the brain relate to motor outcomes after a stroke -- a phenomenon that may be under-recognized in stroke research. The new observational study looked at the relationship between stroke recovery and white matter hyper-intensities (WMHs) -- areas of age-related damage in the brain's white matter, which represent vascular dysfunction and are known to impact cognitive functions.

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Kids With Hypertension May Have Twice the Risk of Cardiac Events

Med Page Today

(MedPage Today) -- Children diagnosed with hypertension had a higher associated long-term risk of major adverse cardiac events (MACE) compared with matched controls without the condition, according to a Canadian population-based, retrospective.

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Paul Appelbaum, MD: What to Warn Patients When Prescribing Psychedelics in the Future

HCPLive

In an interview, Paul Appelbaum, MD, discussed issues clinicians will need to bring up to their patients if the FDA approves a psychedelic-assisted therapy.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Tenax Therapeutics Announces New U.S. Patent Covering the Use of Levosimendan in Pulmonary Hypertension with Heart Failure with Preserved Ejection Fraction (PH-HFpEF)

DAIC

Getty Images milla1cf Mon, 05/06/2024 - 10:48 May 6, 2024 — Tenax Therapeutics, Inc. , a Phase 3, development-stage pharmaceutical company focused on identifying, developing and commercializing products that address cardiovascular and pulmonary diseases with high unmet medical need, announced that the United States Patent and Trademark Office ( USPTO ) has granted the Company a patent covering the use of TNX-103 (oral l evosimendan ), TNX-102 (subcutaneous levosimendan), TNX-101 (IV levosimendan

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Clinical Quiz: Lp(a) Treatments and Therapeutics Considerations

HCPLive

The final in our 3-part quiz series based on the NLA's 2024 update to their 2019 scientific statement on use of lipoprotein(a) in clinical practice focuses on treatment considerations and therapeutic options for elevated Lp(a).

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More Trending

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FDA Advisory Committee Meeting to Review MDMA-Assisted Therapy for PTSD

HCPLive

Lykos Therapeutics' new drug application for MDMA plus psychiatric intervention for adults with PTSD will be the first reviewed by an FDA committee for such a therapy.

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SMT and HeartX Forge Transformative Partnership in Cardiovascular Space

DAIC

milla1cf Mon, 05/06/2024 - 10:55 May 6, 2024 — SMT (Sahajanand Medical Technologies), a leading medical device company at the forefront of innovative patient care in the cardiovascular segment has announced a strategic partnership with HeartX , a pioneering MedTech company focused on research and development. Through this collaboration, SMT gains an innovative product line in the Congenital Heart Defect space.

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With Help From AI, Randy Travis Got His Voice Back After Debilitating Stroke

Med Page Today

(MedPage Today) -- With some help from artificial intelligence (AI), country music star Randy Travis, celebrated for his timeless hits like "Forever and Ever, Amen" and "I Told You So," has his voice back. In July 2013, Travis was hospitalized.

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Large registry data demonstrate PCI for stable CAD can be safely performed before, during or after TAVR

Medical Xpress - Cardiology

New data reveal that percutaneous coronary intervention (PCI) can be safely performed before, during, or after transcatheter aortic valve replacement (TAVR) for patients with stable coronary artery disease (CAD). The results from the analysis were presented at the Society for Cardiovascular Angiography & Interventions (SCAI) 2024 Scientific Sessions.

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Vitamin D May Modulate Immune Function in Chronic HBV Infection

HCPLive

Vitamin D concentration was significant in chronic hepatitis B virus but not hepatitis C virus infection, suggesting its potential impact on immune response.

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SGLT1 and SGLT2 inhibition, circulating metabolites, and cerebral small vessel disease: a mediation Mendelian Randomization study

Cardiovascular Diabetology

Sodium-glucose cotransporter 2 (SGLT2) and SGLT1 inhibitors may have additional beneficial metabolic effects on circulating metabolites beyond glucose regulation, which could contribute to a reduction in the b.

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Embolic Strokes of Undetermined Source: Key Points

American College of Cardiology

The following are key points to remember from a European consensus statement on embolic strokes of undetermined source.

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Discussing the Potential Approval of Tapinarof for Atopic Dermatitis with John Browning, MD

HCPLive

In this interview, Browning discusses his team’s trial data and the implications of the FDA’s decision to accept the supplemental new drug application for tapinarof as an eczema treatment.

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Reduced Ejection Fraction in Elite Endurance Athletes

American College of Cardiology

What is the prevalence, what is the genetic predisposition, and what are the clinical consequences of reduced left (LVEF) and/or right ventricular ejection fraction (RVEF) among endurance athletes?

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Illusion of revascularization: does anyone achieve optimal revascularization during percutaneous coronary intervention?

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 07 May 2024; doi:10.1038/s41569-024-01014-0 In 1993, Lincoff and Topol claimed that the thrombolytic treatment of ST-segment elevation myocardial infarction was suboptimal in many patients and gave an ‘illusion of reperfusion’. In this Perspective article, the authors propose that a similar illusion of revascularization exists for contemporary percutaneous revascularization in patients with coronary artery disease and ischaemia, and identify how outco

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ATTR-ACT Post Hoc Analysis: AFib/AFL Not Predictive of Mortality in Patients With ATTR-CM

American College of Cardiology

Although atrial fibrillation/atrial flutter (AFib/AFL) are common manifestations of transthyretin amyloid cardiomyopathy (ATTR-CM), a post hoc analysis of the ATTR-ACT study, published April 30 in JACC: CardioOncology, found they do not predict all-cause mortality. Furthermore, baseline or historical AFib/AFL did not impact the efficacy of treatment with tafamidis.

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Diabetes and aortic dissection: unraveling the role of 3-hydroxybutyrate through mendelian randomization

Cardiovascular Diabetology

In observational and experimental studies, diabetes has been reported as a protective factor for aortic dissection. 3-Hydroxybutyrate, a key constituent of ketone bodies, has been found to favor improvements i.

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Smoking Cessation Strategies After Initial Treatment Failure

American College of Cardiology

Does treatment with varenicline or combined nicotine replacement therapy (CNRT) improve smoking cessation rates among smokers who do not quit on their initial attempt?

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AI an Effective Geographic Atrophy Screening Tool

HCPLive

Retina specialists and an AI screening tool trained to measure geographic atrophy agreed in a majority of cases, potentially expediting clinical trial enrollment and increasing consistency in measuring the disease.

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HA’s Top 10 Takeaways for Healthcare HR Professionals | ASHHRA ’24

Learning + Leading

If you’re a healthcare human resources professional and missed this year’s fantastic ASHHRA conference in Fort Worth, TX , a few weeks ago we’ve got you covered! We know you’re searching for cutting-edge healthcare HR staffing solutions that will give you the skills insights you need to build smarter training programs. That’s why NHA was there to showcase our variety of healthcare employer staffing solutions.

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Causal Relationship Observed Between Angina Pectoris and Gout Onset

HCPLive

The meta-analysis demonstrated gout with high blood uric acid levels significantly increases the risk of experiencing angina attacks.

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ACC CardiaCast: Exploring HF&T Highlights from ACC.24: RELIEVE-HF, REDUCE AMI, and DANGER-Shock Trials

American College of Cardiology

Dive into the Heart of ACC.24's Heart Failure and Transplant Highlights! In this podcast, Drs. Maya Guglin, Shelley Hall, Onyedika Ilonze, and Kazuhiko Kido dissect the most captivating advancements and groundbreaking revelations from the ACC.24 sessions in heart failure and transplant, including trials RELIEVE-HF, REDUCE-AMI, and DanGer Shock.

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Cytisinicline, a Plant-Based Medication, Could Help Curb E-Cigarette Use Among Adults Patients

HCPLive

Data from the ORCA-V trial suggests cytisinicline, a plant-based medication, aids adults in quitting e-cigarettes.

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Impact of acute glycemic variability on short-term outcomes in patients with ST-segment elevation myocardial infarction: a multicenter population-based study

Cardiovascular Diabetology

Given the increasing attention to glycemic variability (GV) and its potential implications for cardiovascular outcomes. This study aimed to explore the impact of acute GV on short-term outcomes in Chinese pati.

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Ashkan M. Abbey, MD: 3-Year Efficacy of Pegcetacoplan for Geographic Atrophy

HCPLive

At ARVO 2024, Ashkan Abbey, MD describes key data from the pivotal OAKS and DERBY, and the GALE extension trial over 3 years of pegcetacoplan treatment.

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Joint association of TyG index and high sensitivity C-reactive protein with cardiovascular disease: a national cohort study

Cardiovascular Diabetology

Both the triglyceride-glucose (TyG) index, as a surrogate marker of insulin resistance, and systemic inflammation are predictors of cardiovascular diseases; however, little is known about the coexposures and r.

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Clozapine and Second-Generation Antipsychotics for Schizophrenia, with John Kane, MD

HCPLive

The utility of second-generation antipsychotics and clozapine has been less advantageous than it could be, Kane explained.

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Cross-sectional and longitudinal associations of Iron biomarkers and cardiovascular risk factors in pre- and postmenopausal women: leveraging repeated measurements to address natural variability

Cardiovascular Diabetology

The association between iron biomarkers and cardiovascular disease risk factors (CVD-RFs) remains unclear. We aimed to (1) evaluate the cross-sectional and longitudinal associations between iron biomarkers (se.

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Tarcocimab Tedromer Shows Promise for Diabetic Retinopathy in GLOW1

HCPLive

The anti-VEGF agent tarcocimab significantly improved diabetic retinopathy severity score compared with SHAM in a phase 3 study.

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Whole exome sequencing and proteomics-based investigation of the pathogenesis of coronary artery disease with diffuse long lesion

Journal of Cardiothoracic Surgery

The long-term prognosis of patients with coronary artery disease (CAD) with diffuse long lesion underwent coronary artery bypass graft (CABG) or percutaneous coronary intervention (PCI) remains worse. Here, we.

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Ryan McLaughlin, PhD: Challenges Studying Cannabis to Treat Psychiatric Illness

HCPLive

In an interview, Ryan McLaughlin discussed the ethical concerns regarding treating psychiatric illness with cannabis.

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Anomalous circumflex artery encircling the aortic annulus: implications for mitral valve repair

Journal of Cardiothoracic Surgery

Injury to coronary arteries during mitral surgery is a rare but life-threatening procedural complication, an anomalous origin and course of the left circumflex artery (LCx) increase this risk. Recognizing the.

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Upadacitinib Demonstrates Higher Rates of Adverse Events Compared with Adalimumab in PsA

HCPLive

Both overall TEAEs and serious TEAEs were numerically higher in those receiving upadacitinib compared with adalimumab.

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Case Report: Three cases of clinically suspected viral myocarditis with recovery of left ventricular dysfunction

Frontiers in Cardiovascular Medicine

Viral myocarditis is an important cause of non-ischemic cardiomyopathy. Multiple clinical manifestations have been reported, including acute heart failure, cardiogenic shock, and ventricular arrhythmias. We present three patients with clinically suspected viral myocarditis causing acute heart failure. Serum coxsackievirus B antibodies were positive in all three patients.

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HORNBILL: BI 764524 Meets Safety Endpoints in Diabetic Macular Ischemia

HCPLive

BI 764524 was well tolerated following intravitreal administration of single and multiple doses in the phase 1/2a trial, with signs pointing to early efficacy.