Mon.Mar 18, 2024

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8-hour time-restricted eating linked to a 91% higher risk of cardiovascular death

American Heart News - Heart News

Research Highlights: A study of over 20,000 adults found that those who followed an 8-hour time-restricted eating schedule, a type of intermittent fasting, had a 91% higher risk of death from cardiovascular disease. People with heart disease or cancer.

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Is SGLT2 Inhibitor-Associated Ketoacidosis Treated With Enough Insulin?

Med Page Today

(MedPage Today) -- Patients with SGLT2 inhibitor-associated diabetic ketoacidosis (DKA) received significantly lower doses of insulin in the first 24 hours of treatment compared with patients with type 1 diabetes DKA, according to a retrospective.

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Conformal Medical's CLAAS System Demonstrates Low Thrombogenicity Compared to Commercially Available LAAO Devices

DAIC

milla1cf Mon, 03/18/2024 - 07:00 March 18, 2024 — Conformal Medical, Inc. announced that the CLAAS System was featured in a podium presentation at the Cardiovascular Research Technologies (CRT) 2024 conference. Dr. William Gray , Professor of Medicine, Thomas Jefferson University, System Chief, Cardiovascular Diseases at Main Line Health , and Co-Director Lankenau Heart Institute presented "Comparative Acute Thrombogenicity of The CLAAS Foam Implant and Watchman FLX In An In Vitro Blood Loop M

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Aquatic Therapy is Better Than Land-Based Therapy for Women with Fibromyalgia

HCPLive

Aquatic therapy for women with fibromyalgia in Spain is better than land-based therapy for reducing pain levels and improving sleep quality, as seen at the 6-week follow-up.

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SS Innovations’ SSi Mantra Surgical Robotic System used to perform Mitral Valve Replacement

DAIC

milla1cf Mon, 03/18/2024 - 07:30 March 18, 2024 — SS Innovations International, Inc. , a developer of innovative surgical robotic technologies dedicated to making world class robotic surgery affordable and accessible to a global population, today announced that surgeons have successfully performed the world’s first mitral valve replacement using the Made in India, SSi Mantra Surgical Robotic System.

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Omecamtiv Mecarbil in the treatment of heart failure: the past, the present, and the future

Frontiers in Cardiovascular Medicine

Heart failure, a prevailing global health issue, imposes a substantial burden on both healthcare systems and patients worldwide. With an escalating prevalence of heart failure, prolonged survival rates, and an aging demographic, an increasing number of individuals are progressing to more advanced phases of this incapacitating ailment. Against this backdrop, the quest for pharmacological agents capable of addressing the diverse subtypes of heart failure becomes a paramount pursuit.

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Cedars-Sinai Experts Studying Device for Controlling Treatment-Resistant Hypertension

DAIC

milla1cf Mon, 03/18/2024 - 08:00 March 18, 2024 — The Smidt Heart Institute at Cedars-Sinai recently became one of four institutions in the U.S. and the first on the West Coast to use a new device aimed at lowering blood pressure in patients with difficult-to-treat hypertension. Cedars-Sinai is part of a clinical trial testing the safety and efficacy of the device, which is now commercially available after the U.S.

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The Role of Screening, Addressing Cognitive Impairment in Heart Failure Management

HCPLive

Eiran Gorodeski, MD, MPH, Parag Goyal, MD, MSc, and James Fang, MD, discuss the HFSA's recent scientific statement on the prevalence and impact of cognitive impairment on the management of heart failure.

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Black individuals with a genetic mutation found to have increased risk of developing atrial fibrillation, heart failure

Medical Xpress - Cardiology

Physician–scientists from the University of Alabama at Birmingham Marnix E. Heersink School of Medicine led a nationwide genetic study examining the role of genetic mutations in the Titin, TTN, gene in Black individuals. In their study, published in Nature Cardiovascular Research they found that Black individuals carrying these genetic variants were at a high risk of developing atrial fibrillation and heart failure.

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Potential novel biomarkers of coronary heart disease discovered

Science Daily - Heart Disease

Coronary heart disease is a major global health problem, especially among people with type 2 diabetes. Researchers have identified novel protein biomarkers that are associated with the development of CHD in people with and without diabetes.

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Inorganic nitrate can help protect patients against kidney damage caused during coronary angiographic procedures

Medical Xpress - Cardiology

A five-day course of once-daily inorganic nitrate reduces the risk of a serious complication following a coronary angiogram, in which the dye used causes damage to the kidneys. The clinical trial, led by Queen Mary University of London, also showed that the five-day course improves renal outcomes at three months and major adverse cardiac events (MACE) at one year compared to placebo.

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Balancing provider and patient needs: What keeps 1 cardiology leader up at night

Becker's Hospital Review - Cardiology

Vaccines for coronary artery disease and a program that keeps a bed open for critical heart patients are just two elements of his field that light a fire under Vincent Sorrell, MD.

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Scientists' discovery could reduce dependence on animals for vital anticoagulant drug

Medical Xpress - Cardiology

Heparin, the world's most widely used blood thinner, is used during procedures ranging from kidney dialysis to open heart surgery. Currently, heparin is derived from pig intestines, but scientists at Rensselaer Polytechnic Institute (RPI) have discovered how to make it in the lab. They have also developed a path to a biomanufacturing process that could potentially revolutionize how the world gets its supply of this crucial medicine.

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Outcomes of Patients With Discordant High-Gradient AS

American College of Cardiology

What is the prevalence and what are the survival outcomes of patients with discordant high-gradient aortic stenosis (DHG-AS; defined as mean gradient [MG] ≥40 mm Hg and effective orifice area [EOA] >1.0 cm2)?

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Class of Alzheimer's drug presents unique challenge for patients with cardiovascular disease

Medical Xpress - Cardiology

A new Viewpoint article published in the Journal of the American Medical Association (JAMA), titled " Use of Lecanemab for Patients with Cardiovascular Disease—The Challenge of Uncertainty," advocates for additional research to improve decision making prior to initiating lecanemab, commercially known as Leqembi, an FDA-approved Alzheimer's Disease drug.

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Understanding NASH/NAFLD vs MASH/MASLD

HCPLive

In part 1 of this 5-part video series, our experts in hepatology discuss the recent change in nomenclature for NASH/NAFLD as compared to MASH/MASLD and how it effects management.

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Five-minute test during routine GP appointments could prevent stroke

Medical Xpress - Cardiology

People at risk should be tested for atrial fibrillation every time they attend a health appointment, according to results of the AFFECT-EU project, which is holding its final event today in Brussels, Belgium. Patients at high risk of the disorder, such as those with heart failure or prior stroke, should be invited for a screening test.

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Structural Heart Metrics Debut; Amenorrhea-CVD Link; Once-a-Day Antianginal?

Med Page Today

(MedPage Today) -- American societies endorsed five performance measures in valvular and structural heart disease that may be used for public reporting and pay-for-performance programs. (Circulation: Cardiovascular Quality and Outcomes) People.

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Potential novel biomarkers of coronary heart disease discovered

Medical Xpress - Cardiology

Coronary heart disease (CHD) is one of the most common causes of death worldwide—especially in Europe: Here, it is responsible for nearly half of all deaths. Among middle-aged adults, individuals with type 2 diabetes (T2D) have a two to four times higher risk of developing CHD than people without T2D. The research team investigated the predictive performance of protein biomarkers on incident CHD in individuals with and without T2D.

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Stephen Harrison, MD: FDA Approval of Resmetirom Ends Lengthy Road to First NASH Treatment

HCPLive

Harrison discusses important lessons from obeticholic acid’s FDA failure and what set resmetirom apart from its predecessor, poising it to become the first FDA-approved NASH treatment.

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New test shows promise for diagnosing and managing portal hypertension

Medical Xpress - Cardiology

Portal hypertension (PHT) is a severe complication of chronic liver disease, like cirrhosis, where increased pressure builds up in the portal vein. This major blood vessel drains blood from the intestines, spleen, and stomach to the liver. This can lead to life-threatening complications such as internal bleeding and liver failure.

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Post-heart transplant ED visits remain high

Becker's Hospital Review - Cardiology

Philadelphia-based University of Pennsylvania researchers found the number of heart transplant emergency department visits increased with high admission rates but low in-hospital mortality rates.

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How New Therapies Change Discussions Around Screening, Management of MASH

HCPLive

In the final installment in our 5-part video series, our pair of experts in hepatology touch upon how an approval for MASH would impact conversations around screening for asymptomatic patient populations.

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Antiarrhythmic Drugs and Syncope or Pacemaker Implant in AF

American College of Cardiology

What is the association between antiarrhythmic drug (AAD) use and the risk of pacemaker implantation or syncope in patients with new-onset atrial fibrillation (AF) receiving early rhythm control therapy with AADs?

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US Middle-Aged Adults Report Loneliness More Than European Adults: Why Is This?

HCPLive

A new study found late baby boomers and Generation X reported greater levels of loneliness than early baby boomers and the Silent Generation.

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ACC CardiaCast’s PulseCheck: Tricuspid Valve Disease

American College of Cardiology

am-based solutions to the challenges that nurses and allied health professionals face every day. In this panel discussion, host Andrea Price MS, AACC brings together Marcus Burns, DNP, Kristen deAlmeida, PharmD, and Bailey Estes MSN, AGNP-C, to explore best practices related to structural heart disease. In this episode, the focus is on tricuspid valve disease.

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Stephen Harrison, MD: The Role of Weight Loss, Resmetirom in NASH Management

HCPLive

Harrison discusses the role of GLP-1-based therapies in NASH management and situations where resmetirom may be a better option following its recent FDA approval.

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Recognition and management of left atrial dissection during mitral repair

Journal of Cardiothoracic Surgery

Left atrial dissection (LAtD) is a rare but potentially life-threatening complication of mitral valve surgery. Its management is not well stablished in the literature. However, early recognition through intrao.

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Association Observed Linking Anxiety, Depression to Burnout Among Dermatologists

HCPLive

These data highlight the risk of anxiety and depression among dermatologists, with notable findings based on gender differences observed among clinicians.

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High risk of coronary artery obstruction during TAVR, how to avoid it?

Journal of Cardiothoracic Surgery

Coronary artery obstruction after percutaneous aortic replacement is a complication with high short-term mortality secondary to the lack of timely treatment. There are various predictors of coronary obstructio.

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Want A 98% Discount?

Dr. Paddy Barrett

My iPhone is the most inexpensive item I have bought in the last year. By a mile. It's not that I have an old one or that I got it second-hand. It's the latest version, and I paid full price for it. Why is it so cheap? Because of how much value I get from it. On a per-use basis and for what I use it for, it provides insane value. Price is what you pay.

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Later aorta operation after aortic valve replacement for bicuspid aortic valve

Journal of Cardiothoracic Surgery

We investigated long-term outcomes, particularly later aorta operations and overall death in patients who underwent aortic valve replacement for bicuspid aortic valve without aortic surgery.

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Single Frame Echo Quiz

All About Cardiovascular System and Disorders

Transcript of the video: Interpreting an echo quiz just from a single frame has a lot of limitations. But, still for an academic exercise, we will try. Unlike the ECG, where a single image may be more informative, echo usually requires moving images. And moreover, even ECG requires a knowledge of the clinical background before interpretation, to avoid errors.

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A Conversation on Science Integrity, Image Forensics, and Publishing Fraud with Dr. Elisabeth Bik

Physiologically Speaking

Listen to the podcast (audio-only) version here. Dr. Elisabeth Bik is a microbiome scientist. She received her PhD from Utrecht University in the Netherlands. Her scientific work has included time at the Dutch National Institute for Health and the Stanford University School of Medicine.

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What is the meaning of 10% gradient on treadmill?

All About Cardiovascular System and Disorders

Transcript of the video: A question that is often asked is, what is the meaning of 10% gradient in a treadmill test? Usually, in the first stage of Bruce protocol, of treadmill test, there is a 10% gradient in stage 1. That means, if the treadmill length is 150 centimeters, the front end is elevated, about 15 cm from the ground, so that this produces a slope.

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Want $500,000 Worth Of Value?

Dr. Paddy Barrett

When medical interventions are being evaluated for cost-effectiveness, the benchmark for one additional quality year of life is $50,000. This is known as a QALY or Quality Adjusted Life Year. If the intervention costs less than $50,000 per year to provide an additional quality year, it is considered cost-effective. Of course, this is a somewhat arbitrary figure, but we have to start somewhere.

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X-Ray Chest PA View in Severe PAH

All About Cardiovascular System and Disorders

Transcript of the video: Here is an X-ray chest PA view. The striking finding is the huge enlargement of the right pulmonary artery, almost aneurysmal dilatation of right pulmonary artery. Main pulmonary artery is also grossly dilated. And you can see left pulmonary artery shadow and rest of it is not seen here. It will be behind the main pulmonary artery shadow, because left pulmonary artery descends behind the main pulmonary artery and it will be a retrocardiac shadow.

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