Don't Miss a Beat: Semaglutide and the Future of Kidney Disease, with Brendon Neuen, MBBS, PhD
HCPLive
MAY 29, 2024
Brendon Neuen, MBBS, PhD, joins the podcast to discuss the latest updates in nephrology, including the landmark FLOW trial.
Wed.May 29, 2024
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Heart healthy behaviors may help reverse rapid cell aging
American Heart News - Heart News
MAY 29, 2024
Research Highlights: The benefits gained from better heart health may be related to a process involved in the aging of the body and its cells, researchers found in a study of more than 5,000 adults with a mean age of 56 years. People with rapid cell.
Quiz post: two patients with chest pain. Do either, both, or neither have OMI?
Dr. Smith's ECG Blog
MAY 29, 2024
Written by Pendell Meyers Two patients with acute chest pain. Do either, neither, or both have OMI and need reperfusion? Patient 1: Patient 2: Patient 1: A man in his 40s with minimal medical history presented with acute chest pain radiating to his R shoulder. Triage ECG: Click here to sign up for Queen of Hearts Access Three serial troponins were all undetectable.
Heart healthy behaviors may help reverse rapid cell aging
Science Daily - Heart Disease
MAY 29, 2024
The benefits gained with higher lifestyle scores may be associated with the positive influence of heart disease risk factors on the aging of the body and its cells, finds a new study in the Journal of the American Heart Association
Bridging Innovation & Patient Care: The Growing Role of AI
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Redefining IBD Care: Intestinal Ultrasound’s Emerging Role in Treat-to-Target Strategies
HCPLive
MAY 29, 2024
In honor of World Digestive Health Day, this feature examines the growth of intestinal ultrasound in IBD care in the US and how it aligns with STRIDE-II guidance.
Triglycerides Down With ANGPTL3 RNA Interference Agent
Med Page Today
MAY 29, 2024
(MedPage Today) -- An RNA interference therapy, targeting ANGPTL3 in the liver, drastically reduced fasting triglycerides in people with mixed hyperlipidemia, the ARCHES-2 trial showed. Used atop usual statins and other medications, zodasiran.
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Left Ventricular Thrombus after Anterior Myocardial Infarction
The New England Journal of Medicine
MAY 29, 2024
A 70-year-old woman with diabetes presented with epigastric pain and vomiting. ECG showed normal sinus rhythm with pathologic Q waves and T-wave inversions in the anterior leads. Ventriculography and echocardiography are shown in videos.
Metabolic remodelling in atrial fibrillation: manifestations, mechanisms and clinical implications
Nature Reviews - Cardiology
MAY 29, 2024
Nature Reviews Cardiology, Published online: 30 May 2024; doi:10.1038/s41569-024-01038-6 In this Review, the authors describe the changes in metabolism that predispose individuals to developing atrial fibrillation (AF) and highlight the potential of available and emerging therapeutic strategies that target metabolic remodelling to treat AF.
Mayo Clinic AI can predict 4 cardiovascular biomarkers
Becker's Hospital Review - Cardiology
MAY 29, 2024
Using artificial intelligence in angiogram analysis can broaden diagnostic abilities and improve clinical decision-making, according to new research presented May 2 in Long Beach, Calif., at the Society for Cardiovascular Angiography and Interventions' Scientific Sessions 2024.
Traditional Assessment Tools May Underestimate Cardiovascular Risk in AATD
HCPLive
MAY 29, 2024
Patients with AATD had increased cardiovascular risk compared to non-AATD COPD and healthy controls, with results suggesting physiological tests may assess risk more accurately.
Smartwatches and Atrial Fibrillation: What Works and What Needs Improvement?
American College of Cardiology
MAY 29, 2024
As the availability of smartphone-paired devices and smartwatches increases, clinicians will increasingly encounter data generated from consumer-grade devices.
The Disappearance of Private Practice Cardiology
CardiacWire
MAY 29, 2024
In the not too distant past, the vast majority of cardiologists worked their entire careers in private practice, but a range of economic and administrative changes have driven around 70% of US cardiologists into hospital and corporate employment. In today’s issue, we’re diving into cardiology’s employment shift, and what the future holds for private practice cardiologists.
Aortic Valve Calcification and Aortic Stenosis, Microvascular Resistance Reserve After PCI, Microvascular Injury Patterns
American College of Cardiology
MAY 29, 2024
In this week’s View, Dr. Eagle looks at the diagnostic value of aortic valve calcification levels in the assessment of low-gradient aortic stenosis.
Poor Sleep Quality Is Independently Linked to Pain
HCPLive
MAY 29, 2024
In a new study, 16% of patients with RA and 22% with PsA had sleeping issues during the last week.
Evaluate Renal Function With Semaglutide Once Weekly
American College of Cardiology
MAY 29, 2024
The goal of the FLOW trial was to compare the safety and efficacy of semaglutide among patients with chronic kidney disease (CKD) and type 2 diabetes mellitus (DM2).
Diabetes, GLP-1, and Lipid Reduction
HCPLive
MAY 29, 2024
Michael Blaha, MD, highlights the potential of GLP-1 agonists in lowering LDL cholesterol, triglycerides, and body weight in patients with diabetes, presenting them as an additional option for reducing cardiovascular risk in this patient population.
Pericardial Effusion After LA Appendage Closure
American College of Cardiology
MAY 29, 2024
What are the frequency, timing, clinical impact, and predictors of pericardial effusion (PE) after left atrial appendage closure (LAAC)?
PACMAN-AMI: Addition of Alirocumab Lacks Benefit for Endothelial Function
HCPLive
MAY 29, 2024
Alirocumab added to high-intensity statin therapy did not further improve endothelial function in patients with acute myocardial infarction.
Implementation of Obesity Science Into Clinical Practice: Key Points
American College of Cardiology
MAY 29, 2024
The following are key points to remember from an American Heart Association scientific statement on the implementation of obesity science into clinical practice.
Robert Rosenson, MD: RNAi Therapies Show Promise in Mixed Hyperlipidemia
HCPLive
MAY 29, 2024
Robert Rosenson, MD, discusses the unmet need in mixed hyperlipidemia and the potential for RNA interference therapies in this patient population.
Tenecteplase Versus Standard of Care for Minor Ischemic Stroke With Proven Occlusion
American College of Cardiology
MAY 29, 2024
The goal of the TEMPO-2 trial was to evaluate intravenous thrombolytic therapy (tenecteplase) compared with standard therapy among patients with minor acute ischemic stroke.
International experts reach consensus on the labeling of spatial neglect
Science Daily - Stroke
MAY 29, 2024
Using a modified Delphi method, an international team of rehabilitation researchers and clinicians adopted 'spatial neglect' as the standard term for spatial deficits that complicate recovery from brain injury and stroke.
Research hotspots and emerging trends of mesenchymal stem cells in cardiovascular diseases: a bibliometric-based visual analysis
Frontiers in Cardiovascular Medicine
MAY 29, 2024
BackgroundMesenchymal stem cells (MSCs) have important research value and broad application prospects in cardiovascular diseases (CVDs). However, few bibliometric analyses on MSCs in cardiovascular diseases are available. This study aims to provide a thorough review of the cooperation and influence of countries, institutions, authors, and journals in the field of MSCs in cardiovascular diseases, with the provision of discoveries in the latest progress, evolution paths, frontier research hotspots
Similar PK Observed Between High-Concentration, Reference Adalimumab-adbm
HCPLive
MAY 29, 2024
Both the high-concentration and reference formulations of biosimilar adalimumab-adbm exhibited comparable pharmacokinetics and immunogenicity, with a similar safety profile.
Clinical outcomes and aortic remodeling after Castor single-branched stent-graft implantation for type B aortic dissections involving left subclavian artery
Frontiers in Cardiovascular Medicine
MAY 29, 2024
BackgroundThe left subclavian artery (LSA) can be intentionally covered by a stent graft to acquire adequate landing zones for a proximal entry tear near the LSA during thoracic endovascular aortic repair (TEVAR). The Castor single-branched stent graft is designed to treat type B aortic dissection (TBAD) to retain the LSA during TEVAR. This study investigates clinical outcomes, aortic remodeling, and abdominal aortic perfusion patterns after TEVAR with the novel Castor device.MethodsFrom Novembe
Why Are Adult ADHD Cases Climbing?
HCPLive
MAY 29, 2024
Julie Thomas, MS, DMSc, PA-C, discusses why ADHD cases may go undetected into adulthood, and the methods to treat such patients.
How much do you know about PAD (Peripheral Artery Disease)?
CTVS
MAY 29, 2024
Nearly 10 million Americans suffer from the circulatory condition Peripheral Artery Disease, or PAD. PAD occurs when plaque builds up in the arteries and limits blood flow to the lower extremities. This limited blood flow causes poor circulation, which if left un-treated, can severely damage foot and leg tissue, sometimes resulting in non-healing ulcers.
Mortality Risk Unchanged by Iron Dose in Hemodialysis Patients with Cancer
HCPLive
MAY 29, 2024
Iron administration did not increase the mortality risk of hemodialysis patients with cancer, but the safety of increasing ESA doses was not confirmed.
Oral PCSK9 Inhibitor Demonstrated Significant LDL-C Reduction on Top of Statin in Phase I Trial Presented at EAS Congress
DAIC
MAY 29, 2024
Data presented today by AstraZeneca , at the European Atherosclerosis Society (EAS) Congress in France, on AZD0780, an oral PCSK9 inhibitor demonstrated significant LDL-C reduction on top of statin in Phase I trial. Positive results from a Phase I trial of AZD0780, an oral small molecule PCSK9 inhibitor administered on top of statin treatment, were presented at the European Atherosclerosis Society 92nd Congress, ESC 2024, held May 26-29 in Lyon, France.
Oral Corticosteroid Overuse and Uncontrolled Asthma
HCPLive
MAY 29, 2024
Sande Okelo, MD, outlines the factors that contribute to the overuse of oral corticosteroids (OCS), such as nonadherence, poor inhaler technique, inappropriate prescription, and comorbidities, while also discussing strategies to limit OCS overuse and acknowledging that undertreatment can also be a significant issue.
An Auxiliary CHD Diagnostic System Based on Multi-view and Multi-modal Transthoracic Echocardiograms
DAIC
MAY 29, 2024
milla1cf Wed, 05/29/2024 - 07:00 May 29, 2024 — Congenital heart disease (CHD) is one of the most common congenital anomalies worldwide, which brings a heavy health and financial burden to patients. Early CHD screening and treatment can significantly improve children’s prognosis and quality of life. However, inexperienced sonographers often face difficulties in recognizing CHD through transthoracic echocardiogram (TTE) images.
REDUCE-IT Trial and Triglyceride-Lowering Agents
HCPLive
MAY 29, 2024
The panel of medical experts addresses the challenges in raising awareness among healthcare providers about various medications and the need for increased awareness of the REDUCE-IT trial outcomes.
TAVR or SAVR for Failed Bioprosthetic Aortic Valves
American College of Cardiology
MAY 29, 2024
How do mortality and morbidity compare after valve-in-valve (ViV) transcatheter aortic valve replacement (TAVR) versus redo surgical aortic valve replacement (SAVR) for intervention for a failed bioprosthetic SAVR?
High Oral Corticosteroid Dose and Exposure in Asthma
HCPLive
MAY 29, 2024
The panel addresses the issue of patients being exposed to high levels of oral corticosteroids (OCS) without realizing it, as various prescribers can administer steroids. They also discuss the essential questions healthcare professionals should ask to comprehend a patient's total OCS exposure and provide a definition of high OCS use.
Poll: A Puzzling Jigsaw Tale of a Patient With a History of Congenital Heart Disease Presenting With Syncope
American College of Cardiology
MAY 29, 2024
A 26-year-old woman with a history of cardiac surgeries (unknown details) presents with syncope and palpitations. Records obtained from outside institutions show that she has history of dextrocardia with situs solitus.
NRX-101: First Antidepressant to Lower Suicidality in Bipolar Depression
HCPLive
MAY 29, 2024
Unlike approved antidepressant drugs which have warnings on their labels stating they may increase the suicide risk, NRX-101 demonstrates meaningful reductions in suicidality.
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