Wed.Jan 15, 2025

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No Plaque, No Problem: Tackling Atherosclerosis Prevention

Cardiometabolic Health Congress

Atherosclerosisa key driver of cardiovascular disease (CVD)continues to be a significant global health issue. While advances in treatment have reduced mortality in some regions, the atherosclerosis prevention remains challenging. Explore the growing burden of CVD, the rise of new risk factors, and barriers to prevention: The Rising Global Burden of Cardiovascular Disease CVD is now the leading cause of death worldwide, with low- and middle-income countries (LMICs) experiencing the highest burd

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How Smoking Affects Your Heart and Increases Surgery Risk

MIBHS

Smoking is a well-known health hazard, contributing to a wide array of diseases and conditions. Its effects on the heart are particularly alarming, as smoking significantly increases the risk of cardiovascular diseases (CVDs) and complicates medical procedures such as minimally invasive or bloodless heart surgeries. Understanding how smoking affects the heart and raises surgery risks can empower individuals to make healthier choices and improve outcomes when surgical intervention is necessary.

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The Finer Points of FINEARTS-HF

CardiacWire

Bayers FINEARTS-HF study revealed that finerenone could be poised to become the next big heart failure treatment at ESC 2024, and a new series of JACC sub-studies just further strengthened its case. FINEARTS-HF explored the effects of finerenone in ~6k HFmrEF/HFpEF patients and found that the drug significantly reduced worsening HF events and CV death versus placebo.

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Virtual Reality Exercise Game Feasible for Patients With Fibromyalgia

HCPLive

A VR exergame may facilitate patients physical activity while promoting relaxation and positive mental states.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Link between gene duplications and deletions within chromosome region and nonsyndromic bicuspid aortic valve disease

Science Daily - Heart Disease

Large and rare duplications and deletions in a chromosome region known as 22q11.2 , which involves genes that regulate cardiac development, are linked to nonsyndromic bicuspid aortic valve disease.

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Emotional Resilience Linked to Better Quality of Life for Those with Acne

HCPLive

This study pointed to the abilities of patients with acne to adapt to stress and adversity as helpful in making skin-related quality of life improvements.

More Trending

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FDA Approves Mirikizumab (Omvoh) for Crohn’s Disease

HCPLive

The approval is based on data from the phase 3 VIVID-1 study and marks mirikizumabs second approval in IBD, the first being ulcerative colitis in 2023.

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How improving education could close maternal heart health gaps

Science Daily - Heart Disease

Research has established a clear link between racial and ethnic disparities in maternal heart health and higher risks of preterm birth, preeclampsia and cardiovascular issues for Black and Hispanic mothers and their babies.

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ADHD Incidence Trends Fluctuated from 2016 to 2023 in Adults, Adolescents

HCPLive

A new study showed ADHD incidence trends fluctuated between 2016-2023, with adult diagnoses rising post-COVID-19 and adolescent rates remaining stable after an initial decline.

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MUSC Health team 1st in US to implant new heart valve

Becker's Hospital Review - Cardiology

A team from Charleston, S.C.-based MUSC Health's Heart and Vascular Center became the first in the country to implant the Topaz device, a new transcatheter tricuspid heart valve replacement system.

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FCS Patient Case study

HCPLive

Panelists walk through a patient case scenario involving Maria, a 29-year-old woman diagnosed with familial chylomicronemia syndrome (FCS), offering recommendations from each of their specialty perspectives, including dietary modifications, triglyceride-lowering medications, and patient education on managing the condition to prevent recurrent pancreatitis and improve overall quality of life.

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Assessing and Addressing Cardiovascular and Obstetric Risks in Patients Undergoing Assisted Reproductive Technology: A Scientific Statement From the American Heart Association

Circulation

Circulation, Ahead of Print. The use of assisted reproductive technology (ART) is growing, both to assist individuals with infertility and for fertility preservation. Individuals with cardiovascular disease (CVD), or risk factors for CVD, are increasingly using ART. Thus, knowing how to care for patients undergoing ART is important for the cardiovascular clinician.

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Skin of Color Savvy: News Update—SOCS Awards, My Best Winter Skin, & TORPEDO Program

HCPLive

The January 15, 2025 SOCS News Update highlights research ongoing/upcoming initiatives and awards, the My Best Winter Skin Campaign, and the TORPEDO program.

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ACCEL Lite: SUMMIT Trial: Tirzepatide for Heart Failure, Preserved Ejection Fraction and Obesity

American College of Cardiology

In this interview, Drs. Alison Bailey and Milton Packer examine the power of tirzepatide expanding beyond weight loss and treating diabetes in addition to reducing heart failure events in patients with obesity-related HFpEF.

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Genetic Determinants of LDL-C Inversely Linked to Type 2 Diabetes Risk

HCPLive

A cohort study with 14 years of follow-up found monogenic and polygenic mechanisms influencing LDL-C and incident T2D risk inversely associated.

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Clinical significance of a new diagnosis of atrial fibrillation in patients with vascular disease

HeartRhythm

The Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) trial enrolled patients with vascular disease, but excluded patients requiring oral anticoagulation.

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Recognizing Cirrhosis as a Public Health Burden: Cost of Care Tops COPD, Heart Failure

HCPLive

The analysis of UnitedHealth Group claims data found the per-patient cost of cirrhosis care exceeded that of HF and COPD by 21.7% and 55.0%, respectively.

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Dynamic Data-Driven Management of Atrial Fibrillation With Implantable Cardiac Monitors: The MONITOR AF Study

HeartRhythm

Implantable cardiac monitors (ICMs) provide valuable insights into managing atrial fibrillation (AF). Data suggest that ICMs increase AF detection, but their impact on management is still uncertain.

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Oral Linsitinib Reduces Proptosis in Thyroid Eye Disease in Phase 2b/3 Trial

HCPLive

With a Phase 3 trial expected in 2025, linsitinib is the first oral small-molecule therapy to demonstrate statistical significance in thyroid eye disease.

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A CT-based evaluation and comparison of ganglionated plexus targeting techniques for cardioneuroablation

HeartRhythm

Cardioneuroablation (CNA) targets ganglionated plexus (GP) to treat neurally-mediated syncope, yet a standardized GP identification method is lacking. Post-processing of cardiac computed tomography (CT) identifies epicardial fat thus allowing for fat pad identification. While CT-guided CNA's feasibility is documented, data about GP anatomy and comprehensive evaluations of GP targeting methods remain scarce.

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Phase 3 Data Shows Iptacopan Eases Fatigue in C5i-Experienced, -Naïve PNH Patients

HCPLive

2 phase 3 trials show iptacopan improves fatigue, quality of life, and hematologic markers in C5i-experienced or -naive patients with paroxysmal nocturnal hemoglobinuria.

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Peak Frequency Analysis and Functional Substrate Mapping to Predict Critical Isthmus of Atypical Atrial Tachycardia; Findings from a Novel Automated Annotation Algorithm to Detect Near Field Signals

HeartRhythm

Atypical atrial tachycardia (AT) is a commonly encountered rhythm disorder especially in patients with underlying atrial scar. Peak frequency (PF) annotation of bipolar electrograms is a novel method, which mainly aims to discriminate near-field and far-field signals.

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Anti-CGRP mAbs Are Not Linked to Increased CVD Risk in Adults with Migraine

HCPLive

Anti-CGRP monoclonal antibodies for migraine prevention were not linked to increased cardiovascular risk, per a Medicare study, addressing earlier safety concerns.

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Causal association of social determinants of health with mortality and dynamic impact in patients with chronic heart failure: a longitudinal study using marginal structure models

European Journal of Cardiovascular Nursing

Abstract Aims It is unclear whether there is a causal relationship between social determinants of health (SDoH) and mortality in patients with chronic heart failure (CHF). In this study, we assessed causality using inverse probability weighting (IPW) of marginal structural models (MSMs) during the course of CHF. Methods and results A total of 1377 patients with CHF were enrolled in this multi-centre, prospective cohort study from September 2017 onwards.

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SPORT Trial

HCPLive

Panelists discuss how the SPORT trial demonstrated the limited efficacy of dietary supplements compared with traditional lipid-lowering therapies in reducing LDL-C levels.

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Asymptomatic Severe Aortic-Valve Stenosis — To Wait or Not to Wait

The New England Journal of Medicine

Aortic-valve stenosis is an increasingly common clinical condition in the aging population. Population studies indicate a prevalence of up to 2.5% even among persons younger than 75 years of age, with a prevalence of up to 8% in those 75 years of age or older, with large geographic differences between.

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Novel Nonstatin LLTs for Lowering LDL-C and CVD Risk

HCPLive

Panelists discuss how newer nonstatin therapies, such as PCSK9 inhibitors (inclisiran, alirocumab, evolocumab) and bempedoic acid, offer additional options for LDL-C reduction and cardiovascular risk management.

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Southeast Asia Launches First Robotic Cardiac Surgery Procedure, A Collaboration with St. Luke's Medical Center

Society of Thoracic Surgeons - Congenital

News Southeast Asia Launches First Robotic Cardiac Surgery Procedure, A Collaboration with St.

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ChatGPT Could Help Enhance Patient Education Around Glomerular Diseases, Study Finds

HCPLive

ChatGPT effectively simplified information about more than 60 glomerular disease terms to enhance readability, but medical accuracy decreased.

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Normal ECG by many measures. Is it normal?

Dr. Smith's ECG Blog

This was submitted by Hans Helseth, who is applying to med school and who is working as an EKG tech right now. Smith : This patient presented years ago, but came in again while Hans was working. He looked back in time in the patient's chart and saw these ECGs and immediately recognized that they manifested subtle OMI. Also : See Ken Grauer's excellent comments at the bottom.

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Infants Born to Mothers with Alopecia Areata at Increased Risk of Adverse Outcomes

HCPLive

These retrospective data highlight maternal alopecia areatas link with the risk of adverse birth outcomes among infants.

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Surgery for chronic pyothorax after failed amplatzer closure of bronchopleural fistula

Journal of Cardiothoracic Surgery

Background Post-pneumonectomy bronchopleural fistula (BPF) is a life-threatening event whose treatment is not standardized. Case presentation We report the management of a 28-year-old patient with a 3-year history of BPF complicating right pneumonectomy for congenital emphysema. Despite closure by an Amplatzer device, the patient had chronic pyothorax and severely deteriorated general health and quality of life.

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Left atrial appendage occlusion and radiofrequency ablation in a patient with atrial fibrillation and dextrocardia: a case report

Frontiers in Cardiovascular Medicine

BackgroundDextrocardia is a rare congenital condition, affecting approximately 1 in 10,00012,000 individuals. When combined with atrial fibrillation (AF), it becomes even rarer. One-stop surgery, including combined radiofrequency ablation (RFA) and left atrial appendage occlusion (LAAO), has become a common clinical treatment for patients with AF who develop cerebral infarction despite regular oral anticoagulants.

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I Got a Lower-body MRI: Here's What it Told Me about My Muscle Mass

Physiologically Speaking

In this episode, I sit down with Brian Heiderscheit , a professor in the Department of Orthopedics and Rehabilitation at the University of Wisconsin-Madison and director of the Badger Athletic Performance program. Brian also collaborates with Springbok Analytics, a company specializing in advanced full-body MRI scans. Together, we discuss my recent experience with a Springbok scan, how MRI data is revolutionizing athlete performance analysis, and actionable insights for reducing injury risks and

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Efficacy and safety of cardiac myosin inhibitors for symptomatic hypertrophic cardiomyopathy: a meta-analysis of randomized controlled trials

Frontiers in Cardiovascular Medicine

IntroductionHypertrophic cardiomyopathy (HCM) is a common genetic heart disorder. It is characterized by left ventricular hypertrophy and impaired cardiac function, with forms categorized into obstructive (oHCM) and nonobstructive (nHCM). Traditional treatments address symptoms but not the underlying disease mechanism, highlighting the need for novel therapies.

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Enhancing heart and circulatory well-being through optimized radial artery techniques: a meta-analysis of hemostasis and patient comfort

Frontiers in Cardiovascular Medicine

ObjectiveThis meta-analysis elucidates the efficacy of the Transradial Band Device (TR Band) in minimizing complications like radial artery occlusion and hematoma, preserving heart health, and enhancing blood flow post-transradial catheterization.MethodsA comprehensive literature search across databases including PubMed, Cochrane, and Embase examined the impact of radial artery compression techniques and decompression times on complications.