Thu.Jan 11, 2024

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Snow shoveling, cold temperatures combine for perfect storm of heart health hazards

American Heart News - Heart News

DALLAS, Jan. 11, 2024 — Weather forecasters may call it ‘white fluffy stuff,’ however, snow can be a bigger danger than many people may realize. According to the American Heart Association, celebrating its Centennial birthday as the world’s leading.

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Gaps in Practice Appear in Primary Healthcare Physicians Treating Gout

HCPLive

Significant differences in the practice of primary healthcare physicians were observed based on medical specialty when treating and managing asymptomatic hyperuricemia and gout.

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Two common biomarkers can predict heart risk in asymptomatic childhood cancer survivors

Medical Xpress - Cardiology

Data from the St. Jude lifetime cohort study (St. Jude LIFE) have revealed that two common biomarkers of cardiac function and damage could better predict cardiomyopathy within five years than routine clinical evaluations in high-risk, asymptomatic childhood cancer survivors. Early detection through screening using these two biomarkers may lead to earlier treatment to prevent and protect against further heart damage.

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FDA Clears Wegovy, Other GLP-1 Drugs of Suicidality Risk for Now

Med Page Today

(MedPage Today) -- GLP-1 receptor agonists likely don't cause suicidal thoughts or actions, according to a preliminary evaluation by the FDA. The investigation was prompted after the FDA Adverse Event Reporting System received several reports.

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Paragonix SherpaPak Recognized for Maximizing Access to the Donor Pool in New Clinical Study

DAIC

milla1cf Thu, 01/11/2024 - 08:41 January 11, 2024 — Paragonix Technologies , a pioneer in organ transplant solutions, is proud to announce the publication of new groundbreaking data reflecting the clinical impact of its flagship advanced preservation device, the Paragonix SherpaPak Cardiac Transport System (CTS), to protect and monitor donor hearts from extended criteria donors.

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Deroofing, Laser Treatments Introduced for Patients in the UK with Hidradenitis Suppurativa

HCPLive

The THESEUS study was conducted to look at current HS management and the influences on treatment decisions, with the goal of informing future randomized controlled trials.

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Dr. Mike Confronts Dr. Gundry's Controversial Health Views

Med Page Today

(MedPage Today) -- In this video, Mikhail Varshavski, DO -- who goes by "Dr. Mike" on social media -- sits down with cardiothoracic surgeon Steven Gundry, MD, to discuss his controversial health claims. Following is a partial transcript.

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Study looks at cardiovascular risks in COVID-19 survivors

Medical Xpress - Cardiology

The emergence of COVID-19 pandemic caused as a result of severe acute respiratory syndrome-coronavirus marked a global health crisis with over 770 million cases of infection and 6 million deaths by September 6, 2023. Around 6.2% of the recovered individuals, however, face lingering symptoms such as fatigue or respiratory problems.

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In Memoriam: Bruce Wilkoff, MD, FHRS

DAIC

In memoriam: Bruce Wilkoff, MD mtaschetta-millane Thu, 01/11/2024 - 09:56 January 11, 2024 — It is with great sadness that the Diagnostic and Interventional Cardiology ( DAIC ) team has learned of the passing of Bruce Wilkoff, MD, FHRS , Director of the Cardiac Pacing and Tachyarrhythmia Devices in the Cleveland Clinic Department of Cardiovascular Medicine and Professor of Medicine at the Cleveland Clinic Lerner College of Medicine of CWRU , on January 7.

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Intriguing insights uncovered for two rare heart muscle diseases

Medical Xpress - Cardiology

Advancements in the study of two rare heart conditions—peripartum cardiomyopathy (PPCM), and dilated cardiomyopathy (DCM)—contributed by researchers at the Perelman School of Medicine at the University of Pennsylvania may serve as critical guides in future work toward developing therapies for the conditions.

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Chung-Ang University Study Looks at Cardiovascular Risks in COVID-19 Survivors

DAIC

The cumulative incidence of MACE and all- cause of mortality in COVID-19 and non-COVID-19 pneumonia groups. Researchers analyze primary and secondary cardiovascular outcomes in 132,784 inpatients with COVID-19 (October 8, 2020 to September 30, 2021) and 31,173 inpatients with non-COVID-19 pneumonia (January 1, 2019 to December 31, 2019) in Korea. The results indicate a lower risk of cardiovascular disease in COVID-19 patients.

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Clinical Trial Results on Novel Nonstatins Agents.

HCPLive

Expert cardiologists discuss the recent clinical trials results of the CLEAR-OUTCOMES trial and thee sub analysis on the inflammatory marker hcCRP.

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Snow shoveling, cold temperatures combine for perfect storm of heart health hazards

Medical Xpress - Cardiology

Weather forecasters may call it "white fluffy stuff." However, snow can be a bigger danger than many people may realize. According to the American Heart Association, research shows that the exertion of shoveling snow may lead to an increased risk of a heart attack or sudden cardiac arrest.

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Specialized pro-resolving mediators in vascular inflammation and atherosclerotic cardiovascular disease

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 12 January 2024; doi:10.1038/s41569-023-00984-x In this Review, Fredman and Serhan discuss the role of specialized pro-resolving mediators, a superfamily of endogenous signalling lipids that mediate resolution of inflammation processes in atherosclerosis, and appraise the therapeutic potential of specialized pro-resolving mediators for the prevention and treatment of atherosclerosis, and the resolution of uncontrolled vascular inflammation.

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Nitroglycerin use and adverse clinical outcomes in elderly patients with acute coronary syndrome

Open Heart

Objective The primary care for acute coronary syndrome (ACS) includes the administration of nitroglycerin (GTN). This study aimed to investigate the association between the use of GTN before percutaneous coronary intervention (PCI) for ACS and clinical outcomes. Methods Nine-hundred and forty-seven patients who underwent PCI for ACS were examined and classified into two groups: those who were treated with GTN before PCI (GTN group) and those who were not (non-GTN group).

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Epidermal Growth Factor Receptor Inhibitors May Elevate New-Onset Keratitis Risk

HCPLive

Patients with lung cancer treated with EGFR inhibitors may experience a greater risk for keratitis, particularly with afatinib treatment.

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Study reveals new connection between impaired autophagy and heart failure

Medical Xpress - Cardiology

A new study sheds light on how autophagy, the body's process for removing damaged cell parts, when impaired, can play a role in causing heart failure.

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Reduced blood lead levels linked to lower blood pressure

Science Daily - Heart Disease

Researchers found that small declines in blood lead levels were associated with long-term cardiovascular health improvements in American Indian adults. Participants who had the greatest reductions in blood lead levels saw their systolic blood pressure fall by about 7 mm Hg, an amount comparable to the effects of blood pressure-lowering medication.

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Traditional Chinese Medicine Decoction May be Effective Alterative Therapy for Gout

HCPLive

Compared to routine care, TCMD could better reduce the incidence of adverse events and the level of laboratory indicators.

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The Contribution of Declines in Blood Lead Levels to Reductions in Blood Pressure Levels: Longitudinal Evidence in the Strong Heart Family Study

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. BackgroundChronic lead exposure is associated with both subclinical and clinical cardiovascular disease. We evaluated whether declines in blood lead were associated with changes in systolic and diastolic blood pressure in adult American Indian participants from the SHFS (Strong Heart Family Study).Methods and ResultsLead in whole blood was measured in 285 SHFS participants in 1997 to 1999 and 2006 to 2009.

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Looking Into the Future of Lipid Management

HCPLive

Dr Taub, Dr Patel, and Dr Kohli look ahead to the future of the management of cardiovascular risk and hyperlipidemia

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Orthostatic Hypotension in Adults With Hypertension: A Scientific Statement From the American Heart Association

Hypertension Journal

Hypertension, Ahead of Print. Although orthostatic hypotension (OH) has long been recognized as a manifestation of autonomic dysfunction, a growing body of literature has identified OH as a common comorbidity of hypertension. This connection is complex, related to pathophysiology in blood pressure regulation and the manner by which OH is derived as the difference between 2 blood pressure measurements.

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Comparison of Clinical Characteristics, Outcomes in IgA Vasculitis and IgA Nephropathy

HCPLive

Adult patients with IgAV required dialysis sooner and had shorter survival time compared to patients with IgAN.

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Patients with rare heart condition given lifeline through new drug

Medical Xpress - Cardiology

People diagnosed with a life-threatening cardiac condition have been given new hope, thanks to a ground-breaking new drug that protects the heart developed by researchers from UCL and the Royal Free Hospital.

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How to Select Between Available LDL-C Lowering Therapies

HCPLive

Cardiologists discuss how to select the right treatment for your patient with hyperlipidemia

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Higher Noncalcified Plaque Volume Is Associated With Increased Plaque Vulnerability and Vascular Inflammation

Circulation: Cardiovascular Imaging

Circulation: Cardiovascular Imaging, Ahead of Print. BACKGROUND:Recently, it was reported that noncalcified plaque (NCP) volume was an independent predictor for cardiac events. Pericoronary adipose tissue (PCAT) attenuation is a marker of vascular inflammation and has been associated with increased cardiac mortality. The aim of this study was to evaluate the relationships between NCP volume, plaque vulnerability, and PCAT attenuation.METHODS:Patients who underwent preintervention coronary comput

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Reduced blood lead levels linked to lower blood pressure

Medical Xpress - Cardiology

Through the Strong Heart Family Study, researchers have found that small declines in blood lead levels were associated with long-term cardiovascular health improvements in Native American adults. Participants who had the greatest reductions in blood lead levels saw their systolic blood pressure fall by about 7 mm Hg, an amount comparable to the effects of blood pressure-lowering medication.

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Intra-cardiac motion detection catheter for the early identification of acute pericardial tamponade during invasive cardiac procedures

Frontiers in Cardiovascular Medicine

Objectives To develop and test an intra-cardiac catheter fitted with accelerometers to detect acute pericardial effusion prior to the onset of hemodynamic compromise. Background Early detection of an evolving pericardial effusion is critical in ensuring timely treatment. We hypothesized that the reduction in movement of the lateral heart border present in developing pericardial effusions could be quantified by positioning an accelerometer in a lateral cardiac structure.

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'Broken-heart syndrome' patients failed by current treatment, says study

Medical Xpress - Cardiology

In the first-ever study to compare takotsubo patients with heart attack patients and the general population over more than five years, results showed that heart treatments given after takotsubo do not protect patients.

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New Phase 3 Data Announced on Efficacy of Tapinarof for Adults, Children with Atopic Dermatitis

HCPLive

These new, positive data from the ADORING Phase 3 development program showed no new safety signals with long-term use as well as a significant reduction in disease burden.

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Explanatory deep learning to predict elevated pulmonary artery pressure in children with ventricular septal defects using standard chest x-rays: a novel approach

Frontiers in Cardiovascular Medicine

Objective Early risk assessment of pulmonary arterial hypertension (PAH) in patients with congenital heart disease (CHD) is crucial to ensure timely treatment. We hypothesize that applying artificial intelligence (AI) to chest x-rays (CXRs) could identify the future risk of PAH in patients with ventricular septal defect (VSD). Methods A total of 831 VSD patients (161 PAH-VSD, 670 nonPAH-VSD) was retrospectively included.

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Diverting Acute HF Patients From Hospitalization: Case Builds for Short Stay Units

Med Page Today

(MedPage Today) -- For patients presenting to the emergency department (ED) with acute heart failure (AHF), sending select low-risk individuals to the short stay unit (SSU) did not prove to be better than routine hospitalization -- but at least.

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Case Report: Hypereosinophilic syndrome vs. patent foramen ovale as etiopathogenetic contributors to stroke

Frontiers in Cardiovascular Medicine

Hypereosinophilic syndrome (HES), characterized by an increased number of eosinophils in tissues and/or blood, presents with heterogeneous clinical manifestations. Studies have shown that HES can affect the nervous system and may be associated with cerebral infarction. Patent foramen ovale (PFO) is the most common congenital intracardiac defect that can cause right-to-left shunting and contribute to the paradoxical embolization of venous emboli, and even lead to stroke.

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Cardiology Case Report: Armpit Pain

HCPLive

This cardiology case report from Brady Pregerson, MD, features a man in his early 60s with no known medical history presenting with chest pain radiating to both armpits and anterior neck, but not to the back. How would you react?

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Case Report: Acute cerebral infarction caused by left atrial and right ventricular myxoma received emergency operation

Frontiers in Cardiovascular Medicine

Cardiac myxoma is a rare etiology of ischemic stroke, especially in young people. We report a case of multiple myxomas in left atrium and right ventricle inducing acute cerebral infarction. No significant abnormalities were detected in the patient's preoperative laboratory examination. Following emergency surgery, the patient's prognosis was satisfactory, providing valuable empirical insight for the surgical management of acute cerebral infarction in individuals diagnosed with cardiac myxoma.

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Hepatitis C Genotype, Cirrhosis, Gender May Impact Effectiveness of DAA Therapy

HCPLive

Although the overall response rate among the cohort was 96.4%, this figure dropped as low as 66.7% when accounting for male gender, GT3 infection, cirrhosis, obesity, and non-response to previous therapy.

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Palear la nieve y las bajas temperaturas forman una tormenta perfecta de riesgos para la salud del corazón

American Heart News - Heart News

DALLAS, 11 de enero de 2024 — Puede que los meteorólogos hablen de "materia blanca y esponjosa", sin embargo, la nieve puede ser un peligro mayor de lo que mucha gente se imagina. Según la American Heart Association (la Asociación Americana del.

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