Mon.Sep 30, 2024

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Falling May Be a Harbinger of Dementia in Older Adults

Med Page Today

(MedPage Today) -- A new diagnosis of Alzheimer's disease or related dementia was more common after falls than after other traumatic injuries, an analysis of Medicare claims data showed. The study assessed nearly 2.5 million older adults who had.

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Frequent fizzy or fruit drinks and high coffee consumption linked to higher stroke risk

Science Daily - Stroke

Frequent drinking of fizzy drinks or fruit juice is associated with an increased risk of stroke, according to new findings. The research also found that drinking more than four cups of coffee per day also increases the risk of stroke.

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Study Finds More Heart Defects in Kids Conceived With ART

Med Page Today

(MedPage Today) -- Kids born via assisted reproductive technology (ART) had higher risk of congenital heart defects (CHDs), though the absolute risk difference was small, an observational Nordic study of 7.7 million children found. Major CHDs.

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Pregnant IgAN Patients with Adverse Outcomes Less Likely to Reach Proteinuria Remission

HCPLive

A study found pregnant patients with IgA nephropathy and adverse pregnancy outcomes were less likely to achieve proteinuria remission, though renal function remained unaffected.

Outcomes 105
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Study proposes new heart failure treatment targeting abnormal hormone activity

Science Daily - Heart Disease

Scientists discovered that blocking the activity of the hormone glucagon could treat a common and challenging type of heart failure that affects millions worldwide.

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New laser-based headset can measure blood flow, assess risk of stroke

Science Daily - Stroke

Researchers have developed a laser-based device that can measure blood flow noninvasively and differentiate stroke risk based on current physiological conditions.

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Mavacamten Shows Promise in Heart Failure With Normal to Supranormal EF

Med Page Today

(MedPage Today) -- There may be a future for cardiac myosin inhibitors in heart failure with preserved ejection fraction (HFpEF), according to the proof-of-concept EMBARK-HFpEF trial. An established cardiac myosin inhibitor for hypertrophic cardiomyopathy.

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The Medical Sisterhood: Confronting Imposter Syndrome, with Tina Bhutani, MD, MAS

HCPLive

In this episode, Tina Bhutani, MD, MAS, joins The Medical Sisterhood for a discussion about confronting imposter syndrome as a woman in medicine.

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Why People Struggle To Get A Proper Heart Disease Risk Assessment.

Dr. Paddy Barrett

"Frustrated, lost and confused." That was the main feedback I got from thousands of readers when I asked them about their experience working with existing healthcare systems to implement a plan to prevent heart disease. This is not good. Heart disease is the leading cause of death worldwide, and with the right approaches, 80% or more can be prevented at an early age.

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Heart transplant patients from socioeconomically deprived areas face higher risk for postoperative complications, earlier death than others

Science Daily - Heart Disease

Heart transplant patients who live in socioeconomically disadvantaged areas are more likely to experience post-surgical complications and die within five years than patients who live in more advantaged areas, even when those patients were transplanted at topnotch high-volume hospitals.

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Family Heart Foundation Launches Cholesterol Connect: Free At-Home Lipid Screening

HCPLive

Family Heart Foundation announces the launch of Cholesterol Connect, a program that provides free at-home lipid screening and personalized support.

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Does Screening for Atrial Fibrillation Reduce Stroke Risk?

NEJM Journal Watch - Cardiology

A 14-day monitor detected more atrial fibrillation but did not affect hospitalization rates for stroke or hemorrhage.

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Case Strengthens for Cardiac Myosin Inhibitor in SEQUOIA-HCM

Med Page Today

(MedPage Today) -- Secondary efficacy analyses of the pivotal SEQUOIA-HCM trial continued to favor aficamten, supporting a potential role for another cardiac myosin inhibitor in obstructive hypertrophic cardiomyopathy (HCM). In these randomized.

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ACC CardiaCast: 2024 Update to the AHA/ACC HCM Guideline: Expert Interpretation for Application to Practice in Latin America

American College of Cardiology

In this episode of CardiaCast, world-renowned hypertrophic cardiomyopathy (HCM) expert Dr. Matthew Martinez will discuss with Dr. Cesar Herrera challenges that exist in Latin America related to the application of the recently issued guideline, “2024 AHA/ACC/AMSSM/HRS/PACES/SCMR Guideline for the Management of Hypertrophic Cardiomyopathy: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines.

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Pulmonary artery mass with PIK3CA mutation after orthotopic heart transplantation

Journal of Cardiothoracic Surgery

Patients can develop de novo malignancies following orthotopic heart transplantation. However, vascular tumors are not commonly described in this population.

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Lung Imaging 2.0: How AI is Shaping the Future with Rachel Eddy, PhD

HCPLive

The latest episode of Lungcast explores the evolving field of pulmonary imaging technology and the transformative impact of artificial intelligence.

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Efficacy and Safety of Lerodalcibep in Patients at Very High and High Risk for Cardiovascular Disease

American College of Cardiology

The goal of the LIBerate-HR trial was to evaluate lerodalcibep compared with placebo among patients with increased risk of cardiovascular disease (CVD). Lerodalcibep blocks PCSK9 binding to low-density lipoprotein (LDL)-receptors, thus preventing receptor degradation, which enhances LDL-C clearance and lowering of LDL-C levels.

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Type a aortic dissection after aortic wrapping performed 26 years ago: a case report

Journal of Cardiothoracic Surgery

Aortic wrapping (AW) has been performed as a less invasive alternative to aortoplasty. However, AW can also cause long-term aortic complications. In this report, we present a rare case of a dissecting aortic a.

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The Importance of Regular Heart Check-Ups: What You Need to Know

AMS Cardiology

Heart disease is a leading cause of death worldwide. However, many cases can be prevented or detected early through regular check-ups. At AMS Cardiology, we believe proactive care is essential for maintaining optimal heart health. Below we’ll discuss the importance of heart screenings , check-ups and cardiac disease prevention and why choosing AMS Cardiology for your care is the right decision.

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Overdiagnosing giant bullous emphysema as metastatic adenocarcinoma: a case report

Journal of Cardiothoracic Surgery

Giant bullous emphysema is characterized by large bullae occupying at least one-third of the hemithorax and leading to compression of the surrounding lung parenchyma. Overdiagnosis can occur because of the aty.

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Dobutamine stress echocardiography after positive CCTA: diagnostic performance using fractional flow reserve and instantaneous wave-free ratio as reference standards

Open Heart

Aims To assess the diagnostic accuracy of dobutamine stress echocardiography (DSE) in symptomatic patients with a low to intermediate pretest probability of obstructive coronary artery disease (CAD) and a positive coronary CT angiography (CCTA). Methods We prospectively enrolled 104 consecutive patients undergoing coronary angiography for symptoms of stable CAD and a CCTA indicative of obstructive CAD.

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Successful occluder removal and reocclusion of an atrial septal defect after occluder immigration to aortic arch: a case report

Journal of Cardiothoracic Surgery

Atrial septal defect (ASD) is a common congenital heart disease, and currently, transcatheter intervention is the most common clinical treatment method. However, certain complications still occur during the pe.

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Prehospital factors predicting mortality in patients with shock: state-wide linkage study

Open Heart

Background Patients with shock treated by emergency medical services (EMS) have high morbidity and mortality. Knowledge of prehospital factors predicting outcomes in patients with shock remains limited. We aimed to describe the prehospital predictors of mortality in patients with non-traumatic shock transported to hospital by EMS. Method This is a retrospective cohort study of consecutive ambulance attendances for non-traumatic shock in Victoria, Australia (January 2015–June 2019) linked w

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Emerging Research of RNAi-Based Therapies for FCS

HCPLive

Panelists discuss how early diagnosis and intervention in familial chylomicronemia syndrome (FCS) are crucial for preventing cardiovascular and metabolic complications, emphasizing the key role clinicians play in initiating timely and effective treatment strategies.

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Congenital Heart Defects: Helping Families Navigate the Challenges

MIBHS

Congenital heart defects (CHDs) are the most common type of birth defect, affecting nearly 1 in 100 newborns. These structural abnormalities of the heart are present at birth. They can range from simple issues that require minimal or no treatment to complex conditions that necessitate multiple surgeries and lifelong care. For families, the journey from diagnosis to treatment and beyond is often filled with uncertainty, emotional strain, and complex decisions.

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PALISADE Study: Plozasiran’s Efficacy and Potential in Reducing Triglycerides and Pancreatitis

HCPLive

Panelists discuss how a multidisciplinary approach enhances the management of familial chylomicronemia syndrome by fostering collaboration among clinicians to address unmet treatment needs and optimize patient outcomes, while also exploring existing treatment gaps that contribute to ongoing risks of acute pancreatitis and hospitalization.

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Presence of subclinical atherosclerosis is marker of mortality and its progression increases risk of death

Science Daily - Heart Disease

A new study also shows imaging for early detection and monitoring can improve prediction and prevention of premature death.

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Positive Phase 2a Data Suggest Disease-Modifying Potential of CNP-104 in PBC

HCPLive

Positive 120-day data from the phase 2a study of CNP-104 in PBC highlight its efficacy across multiple immunological and clinical measurements

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Meta-Analysis of MRA Use in HF

American College of Cardiology

What is the association of mineralocorticoid receptor antagonist (MRA) use in clinical trials of patients with heart failure (HF) across the left ventricular ejection fraction (EF) spectrum?

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TransCon hGH Aims for FDA Label Expansion for Adult Growth Hormone Deficiency

HCPLive

Ascendis Pharma has submitted a sBLA to the FDA for TransCon hGH for the treatment of adults with growth hormone deficiency.

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Delayed Remote Ischemic Preconditioning for Cardiac Surgery

American College of Cardiology

What is the impact of delayed remote ischemic preconditioning (RIPC) on the occurrence of acute kidney injury (AKI) and postoperative complications in patients undergoing cardiac surgery?

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Systemic Treatments and Switching Therapy in Atopic Dermatitis

HCPLive

Medical experts evaluate the role of biologics in atopic dermatitis, including their efficacy and safety, and discuss reasons for switching between systemic treatments.

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Multienergy Computed Tomography Imaging: Cardiovascular Applications

American College of Cardiology

Computed tomography (CT) relies on the passage and attenuation of X-ray photons to create an image.

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Deuruxolitinib Twice-Daily Improves Hair Satisfaction Among Patients with Alopecia Areata

HCPLive

New data presented by Sun Pharma at EADV 2024 highlight the impact of deuruxolitinib 8 mg treatment of adults with severe alopecia areata.

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Stakeholder perceptions of factors contributing to effective implementation of exercise cardiac telerehabilitation in clinical practice

European Journal of Cardiovascular Nursing

Abstract Aims Cardiac exercise telerehabilitation is effective and can be cost-effective for managing ischaemic heart disease, but implementation of evidence-based interventions in clinical practice remains a challenge. We aimed to identify factors that cardiac rehabilitation stakeholders perceived could influence the effectiveness of implementing an evidence-based, real-time remotely monitored cardiac exercise telerehabilitation intervention (REMOTE-CR).

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Sherona Bau, NP: Navigating MELD Criteria Challenges for Liver Transplant Referral

HCPLive

Bau explains the challenges of using MELD to determine liver transplant referrals and other complexities of the evaluation process.

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Left atrioventricular valve regurgitation repair with concomitant outflow obstruction release on repaired atrioventricular septal defect case

Journal of Cardiothoracic Surgery

Left ventricular outflow tract stenosis and atrioventricular valve regurgitation are often problems encountered in adulthood after complete atrioventricular septal defect repair. The surgical approach and indi.