Dr. Smith's ECG Blog

JUNE 17, 2024

Written by Bobby Nicholson, MD 67 year old male with history of hypertension and hyperlipidemia presented to the Emergency Department via ambulance with midsternal nonradiating chest pain and dyspnea on exertion. Pain improved to 1/10 after EMS administers 324 mg aspirin and the following EKG is obtained at triage. What do you think? If this EKG were handed to you to screen from triage without any clinical information, what would you think?

Chest Pain 137

Chest Pain Embolism Pulmonary Tachycardia 137

Med Page Today

JUNE 17, 2024

(MedPage Today) -- There was a steady increase in the prevalence of chronic hypertension in pregnancy over the last two decades, with some accompanying changes in treatment, a nationwide cohort study found. From 2008 to 2021, the prevalence of.

Hypertension 116

Hypertension 116

Medical Xpress - Cardiology

JUNE 17, 2024

Generative Artificial Intelligence (Gen AI) can rapidly and accurately screen patients for clinical trial eligibility, according to a new study from Mass General Brigham researchers. Such technology could make it faster and cheaper to evaluate new treatments and, ultimately, help bring successful ones to patients.

Research 110

Research Heart Failure Technology 110

DAIC

JUNE 17, 2024

milla1cf Mon, 06/17/2024 - 20:34 June 17, 2024 — aycan , a recognized leader in medical imaging, announced today a reseller and technology partnership with AI4MedImaging, a company that specializes in applying artificial intelligence ( AI ) to medical imaging. aycan launched its official partnership with AI4MedImaging this week by offering their groundbreaking AI4CMR solution, a Software as a Medical Device (SaMD) that aims to automate the interpretation of cardiac magnetic resonance imaging (CM

Technology 105

Technology Innovation Patient Care 105

Medical Xpress - Cardiology

JUNE 17, 2024

A new smartphone face-screening tool could help paramedics to identify stroke in seconds—much sooner and more accurately than is possible with current technologies.

Stroke 112

Stroke Strokes Technology 112

HCPLive

JUNE 17, 2024

Patients with psoriasis on biological agents might have a lower PsA risk than those on methotrexate, but patients on topical therapy have an even lower risk, a study found.

105

105

Medical Xpress - Cardiology

JUNE 17, 2024

A team of researchers led by Monash University and the Baker Heart and Diabetes Institute have published the first compelling evidence of the therapeutic potential of a new therapy to treat hypertension-induced organ damage. The paper appears in the journal Cardiovascular Research.

Hypertension 104

Hypertension Research Diabetes 104

JAMA Cardiology

JUNE 17, 2024

This randomized clinical trial investigates the effectiveness and safety of a nonphysician-led, multifaceted, intensive blood pressure intervention in younger and older individuals with hypertension.

Blood Pressure 104

Blood Pressure Hypertension 104

Journal of Clinical Investigation - Cardiology

JUNE 17, 2024

Cancer cells exhibit heightened secretory states that drive tumor progression. Here, we identified a chromosome 3q amplicon that serves as a platform for secretory regulation in cancer. The 3q amplicon encodes multiple Golgi-resident proteins, including the scaffold Golgi integral membrane protein 4 (GOLIM4) and the ion channel ATPase secretory pathway Ca2+ transporting 1 (ATP2C1).

Cancer 98

Cancer 98

HCPLive

JUNE 17, 2024

At EULAR, Tonix Pharmaceuticals presented the phase 3 RESILIENT trial which met the primary endpoint of TNX-102 SL reducing daily pain intensity.

105

105

Science Daily - Heart Disease

JUNE 17, 2024

The number of individuals in the U.S. who had chronic hypertension or chronic high blood pressure during pregnancy doubled between 2008 and 2021.

Blood Pressure 103

Blood Pressure Hypertension 103

Journal of Clinical Investigation - Cardiology

JUNE 17, 2024

Background Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S) is a rare, autosomal dominant, universally fatal disease without effective treatment options. This study explores the safety and preliminary efficacy of crizanlizumab, a humanized monoclonal antibody against P-selectin approved for the prevention of sickle cell crises, in slowing retinal nonperfusion and preserving vision in patients with RVCL-S.METHODS Eleven patients with RVCL-S with confirme

Biomarkers 116

Biomarkers Research Innovation Education 116

Science Daily - Heart Disease

JUNE 17, 2024

Researchers have discovered new insights into the human heart's structure, revealing its evolutionary history. This study enhances understanding of heart development and its implications for treating heart disease.

Research 87

Research Heart Disease 87

Science Daily - Stroke

JUNE 17, 2024

A new smartphone face-screening tool could help paramedics to identify stroke in seconds -- much sooner and more accurately than is possible with current technologies. Strokes, which affect millions of people globally, occur when the blood supply to part of the brain is interrupted or reduced, which prevent brain tissue from getting oxygen and nutrients.

Stroke 78

Stroke Strokes Technology 78

Becker's Hospital Review - Cardiology

JUNE 17, 2024

Patients with heart failure, or suspected of having it, are not being diagnosed quickly enough, according to a study involving 8,000 patients, which was presented June 15 at the Heart Failure Association of the European Society of Cardiology.

Heart Failure 72

Heart Failure 72

HCPLive

JUNE 17, 2024

This episode covers the clearance of 2 new OTC CGMs from Abbott, JDRF becoming Breakthrough T1D, and the FDA clearance of the CamAPS FX for people with T1D

Diabetes 78

Diabetes 78

JAMA Cardiology

JUNE 17, 2024

This genetic association study evaluated genetic variants associated with increased risk of vasospastic angina.

Angina 99

Angina Myocardial Infarction 99

HCPLive

JUNE 17, 2024

Interim analyses of a pair of phase 2b studies highlight the IBAT inhibitor’s potential in adults with primary biliary cholangitis and primary sclerosing cholangitis.

69

69

JAMA Cardiology

JUNE 17, 2024

“You can always depend on Americans to do the right thing—after they’ve tried everything else.” Winston Churchill was not thinking of US health care in this famous quote often attributed to him.

Blood Pressure 76

Blood Pressure 76

Journal of Clinical Investigation - Cardiology

JUNE 17, 2024

Although cancer has long been considered a genetic disease, increasing evidence shows that epigenetic aberrations play a crucial role in affecting tumor biology and therapeutic response. The dysregulated epigenome in cancer cells reprograms the immune landscape within the tumor microenvironment, thereby hindering antitumor immunity, promoting tumor progression, and inducing immunotherapy resistance.

Cancer 93

Cancer 93

American College of Cardiology

JUNE 17, 2024

Women continue to be underrepresented as authors of cardiovascular publications, according to the results of a study of a decade's worth of papers from four cardiovascular journals, published in JACC.

Article 68

Article 68

Circulation

JUNE 17, 2024

Circulation, Ahead of Print. Valvular heart disease is a common cause of morbidity and mortality worldwide and has no effective medical therapy. Severe disease is managed with valve replacement procedures, which entail high health care–related costs and postprocedural morbidity and mortality. Robust ongoing research programs have elucidated many important molecular pathways contributing to primary valvular heart disease.

Bicuspid/Mitral 65

Bicuspid/Mitral Heart Disease Aortic valve Heart Valves 65

Cardiovascular Diabetology

JUNE 17, 2024

Elevated plasma glucose levels are common in patients suffering acute ischemic stroke (AIS), and acute hyperglycemia has been defined as an independent determinant of adverse outcomes. The impact of acute-to-c.

Outcomes 59

Outcomes Stroke Strokes Diabetes 59

Medical Xpress - Cardiology

JUNE 17, 2024

The number of individuals in the U.S. who had chronic hypertension or chronic high blood pressure during pregnancy doubled between 2008 and 2021, while the prescribing and filling of antihypertensive medication during pregnancy remained low but stable at 60%, according to research published in Hypertension.

Blood Pressure 59

Blood Pressure Hypertension Research 59

Cardiovascular Diabetology

JUNE 17, 2024

Despite the high burden of obesity and Type 2 diabetes (T2DM) in the Middle East/West Asia region, the effect of weight change on the development of T2DM is poorly addressed. Therefore, we aimed to assess the.

Diabetes 59

Diabetes Obesity Research 59

HCPLive

JUNE 17, 2024

The network meta-analysis found tenofovir disoproxil fumarate was more likely to achieve virologic response at week 48, while entecavir was superior for 48-week biochemical response.

59

59

Science Daily - Stroke

JUNE 17, 2024

A new study has found that a novel discourse treatment improved the communication abilities of people with aphasia, a language disorder commonly resulting from stroke.

Stroke 58

Stroke Strokes 58

HCPLive

JUNE 17, 2024

Results revealed cDAPSA can help providers accurately measure the level of disease activity in patients and predict whether the patient will have radiographic progression.

59

59

Journal of Clinical Investigation - Cardiology

JUNE 17, 2024

Psilocybin, MDMA, and ketamine have emerged as potentially effective treatments for rapid amelioration of the symptoms of mood and related psychiatric disorders. All clinical data collected so far with regard to psilocybin or MDMA, which have reported positive outcomes for treating depression, anxiety, posttraumatic stress disorder, and drug or alcohol use disorders, have involved clinician-assisted intervention.

Outcomes 80

Outcomes 80

HCPLive

JUNE 17, 2024

Daniel Blockmans, MD, PhD, discussed the results of a phase 3 trial that revealed upadacitinib significantly improved outcomes in patients with giant cell arteritis.

Outcomes 59

Outcomes 59

HeartRhythm

JUNE 17, 2024

The association between serum potassium and atrial fibrillation (AF) recurrence after catheter ablation remains unclear.

Atrial Fibrillation 75

Atrial Fibrillation Ablation 75

HCPLive

JUNE 17, 2024

Analysis of NHANES data from 1999 to 2020 provides some evidence of diet quality improvement but highlights low rates of adults achieving ideal diet quality.

Diet 59

Diet 59

Journal of Cardiothoracic Surgery

JUNE 17, 2024

The surgical treatment strategy for aortic arch pathology with a shaggy aorta must be determined on a case-by-case basis because of the risk of catastrophic complications, such as brain infarction and spinal c.

Aortic 52

Aortic 52

HCPLive

JUNE 17, 2024

These data may require large-scale studies to duplicate the findings, evaluating individuals with psoriasis who had PPM for IE antibiotic prophylaxis.

Pacemaker 59

Pacemaker 59

Frontiers in Cardiovascular Medicine

JUNE 17, 2024

The incidence of atrial fibrillation (AF) is significantly higher in patients with pacemakers than in the general population, which could be due to patient characteristics and the diagnostic tool of the pacemaker in detecting atrial high-rate episodes and subclinical AF, but also to the pacemaker itself providing AF-promoting conditions. It is well known that high ventricular pacemaker burden increases the likelihood of AF occurrence.

Pacemaker 52

Pacemaker Atrial Fibrillation Electrophysiology 52

HCPLive

JUNE 17, 2024

Expert gastroenterologists delve into the concept of transmural healing as a treatment target for both ulcerative colitis and Crohn's disease, sharing insights on their preferred timeframes for reassessing treatment progress, monitoring methods, and the effectiveness of intestinal ultrasounds in the management of these conditions.

Ultrasound 52

Ultrasound 52

Frontiers in Cardiovascular Medicine

JUNE 17, 2024

BackgroundWhile Traditional Chinese Medicine (TCM) boasts an extensive historical lineage and abundant clinical expertise in addressing atherosclerosis, this field is yet to be penetrated adequately by bibliometric studies. This study is envisaged to evaluate the contemporary scenario of TCM in conjunction with atherosclerosis over the preceding decade while also identifying forthcoming research trends and emerging topics via the lens of bibliometric analysis.MethodsLiterature pertaining to TCM

Atherosclerosis 52

Atherosclerosis Research Article Circulation 52