Dr. Smith's ECG Blog

JUNE 17, 2024

Written by Bobby Nicholson, MD 67 year old male with history of hypertension and hyperlipidemia presented to the Emergency Department via ambulance with midsternal nonradiating chest pain and dyspnea on exertion. Pain improved to 1/10 after EMS administers 324 mg aspirin and the following EKG is obtained at triage. What do you think? If this EKG were handed to you to screen from triage without any clinical information, what would you think?

Chest Pain 140

Chest Pain Embolism Pulmonary Tachycardia 140

American Heart News - Heart News

JUNE 17, 2024

Research Highlights: The number of individuals in the United States who had chronic hypertension or chronic high blood pressure during pregnancy doubled between 2008 and 2021, according to a nationwide review of private health insurance.

Blood Pressure 122

Blood Pressure Hypertension Research 122

Med Page Today

JUNE 17, 2024

(MedPage Today) -- There was a steady increase in the prevalence of chronic hypertension in pregnancy over the last two decades, with some accompanying changes in treatment, a nationwide cohort study found. From 2008 to 2021, the prevalence of.

Hypertension 114

Hypertension 114

JAMA Cardiology

JUNE 17, 2024

This randomized clinical trial investigates the effectiveness and safety of a nonphysician-led, multifaceted, intensive blood pressure intervention in younger and older individuals with hypertension.

Blood Pressure 107

Blood Pressure Hypertension 107

HCPLive

JUNE 17, 2024

At EULAR, Tonix Pharmaceuticals presented the phase 3 RESILIENT trial which met the primary endpoint of TNX-102 SL reducing daily pain intensity.

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105

DAIC

JUNE 17, 2024

milla1cf Mon, 06/17/2024 - 20:38 June 17, 2024 — Elutia Inc. , a pioneer in drug-eluting biomatrix products, today announced that its Antibiotic-Eluting BioEnvelope, EluPro (referred to as CanGaroo during development), has received clearance from the U.S. Food and Drug Administration ( FDA ). Specifically designed to prevent post-operative complications for devices such as pacemakers and defibrillators, EluPro incorporates powerful antibiotic therapy combined with advanced tissue engineering to

Pacemaker 105

Pacemaker Defibrillator Electrophysiology Hospital 105

HCPLive

JUNE 17, 2024

Patients with psoriasis on biological agents might have a lower PsA risk than those on methotrexate, but patients on topical therapy have an even lower risk, a study found.

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105

JAMA Cardiology

JUNE 17, 2024

This genetic association study evaluated genetic variants associated with increased risk of vasospastic angina.

Angina 104

Angina Myocardial Infarction 104

Science Daily - Heart Disease

JUNE 17, 2024

The number of individuals in the U.S. who had chronic hypertension or chronic high blood pressure during pregnancy doubled between 2008 and 2021.

Blood Pressure 99

Blood Pressure Hypertension 99

Journal of Clinical Investigation - Cardiology

JUNE 17, 2024

Cancer cells exhibit heightened secretory states that drive tumor progression. Here, we identified a chromosome 3q amplicon that serves as a platform for secretory regulation in cancer. The 3q amplicon encodes multiple Golgi-resident proteins, including the scaffold Golgi integral membrane protein 4 (GOLIM4) and the ion channel ATPase secretory pathway Ca2+ transporting 1 (ATP2C1).

Cancer 98

Cancer 98

Medical Xpress - Cardiology

JUNE 17, 2024

Generative Artificial Intelligence (Gen AI) can rapidly and accurately screen patients for clinical trial eligibility, according to a new study from Mass General Brigham researchers. Such technology could make it faster and cheaper to evaluate new treatments and, ultimately, help bring successful ones to patients.

Research 86

Research Heart Failure Technology 86

Journal of Clinical Investigation - Cardiology

JUNE 17, 2024

Background Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S) is a rare, autosomal dominant, universally fatal disease without effective treatment options. This study explores the safety and preliminary efficacy of crizanlizumab, a humanized monoclonal antibody against P-selectin approved for the prevention of sickle cell crises, in slowing retinal nonperfusion and preserving vision in patients with RVCL-S.METHODS Eleven patients with RVCL-S with confirme

Biomarkers 91

Biomarkers Research Innovation Education 91

Medical Xpress - Cardiology

JUNE 17, 2024

A new smartphone face-screening tool could help paramedics to identify stroke in seconds—much sooner and more accurately than is possible with current technologies.

Strokes 83

Strokes Stroke Technology 83

Science Daily - Heart Disease

JUNE 17, 2024

Researchers have discovered new insights into the human heart's structure, revealing its evolutionary history. This study enhances understanding of heart development and its implications for treating heart disease.

Research 81

Research Heart Disease 81

Medical Xpress - Cardiology

JUNE 17, 2024

A team of researchers led by Monash University and the Baker Heart and Diabetes Institute have published the first compelling evidence of the therapeutic potential of a new therapy to treat hypertension-induced organ damage. The paper appears in the journal Cardiovascular Research.

Hypertension 82

Hypertension Research Diabetes 82

Science Daily - Stroke

JUNE 17, 2024

A new smartphone face-screening tool could help paramedics to identify stroke in seconds -- much sooner and more accurately than is possible with current technologies. Strokes, which affect millions of people globally, occur when the blood supply to part of the brain is interrupted or reduced, which prevent brain tissue from getting oxygen and nutrients.

Strokes 79

Strokes Stroke Technology 79

HCPLive

JUNE 17, 2024

This episode covers the clearance of 2 new OTC CGMs from Abbott, JDRF becoming Breakthrough T1D, and the FDA clearance of the CamAPS FX for people with T1D

Diabetes 78

Diabetes 78

JAMA Cardiology

JUNE 17, 2024

“You can always depend on Americans to do the right thing—after they’ve tried everything else.” Winston Churchill was not thinking of US health care in this famous quote often attributed to him.

Blood Pressure 77

Blood Pressure 77

HeartRhythm

JUNE 17, 2024

The association between serum potassium and atrial fibrillation (AF) recurrence after catheter ablation remains unclear.

Atrial Fibrillation 75

Atrial Fibrillation Ablation 75

Becker's Hospital Review - Cardiology

JUNE 17, 2024

Patients with heart failure, or suspected of having it, are not being diagnosed quickly enough, according to a study involving 8,000 patients, which was presented June 15 at the Heart Failure Association of the European Society of Cardiology.

Heart Failure 72

Heart Failure 72

Journal of Clinical Investigation - Cardiology

JUNE 17, 2024

Although cancer has long been considered a genetic disease, increasing evidence shows that epigenetic aberrations play a crucial role in affecting tumor biology and therapeutic response. The dysregulated epigenome in cancer cells reprograms the immune landscape within the tumor microenvironment, thereby hindering antitumor immunity, promoting tumor progression, and inducing immunotherapy resistance.

Cancer 71

Cancer 71

HCPLive

JUNE 17, 2024

Interim analyses of a pair of phase 2b studies highlight the IBAT inhibitor’s potential in adults with primary biliary cholangitis and primary sclerosing cholangitis.

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69

American College of Cardiology

JUNE 17, 2024

Women continue to be underrepresented as authors of cardiovascular publications, according to the results of a study of a decade's worth of papers from four cardiovascular journals, published in JACC.

Article 67

Article 67

Circulation

JUNE 17, 2024

Circulation, Ahead of Print. Valvular heart disease is a common cause of morbidity and mortality worldwide and has no effective medical therapy. Severe disease is managed with valve replacement procedures, which entail high health care–related costs and postprocedural morbidity and mortality. Robust ongoing research programs have elucidated many important molecular pathways contributing to primary valvular heart disease.

Bicuspid/Mitral 65

Bicuspid/Mitral Heart Disease Aortic valve Heart Valves 65

Journal of Clinical Investigation - Cardiology

JUNE 17, 2024

Psilocybin, MDMA, and ketamine have emerged as potentially effective treatments for rapid amelioration of the symptoms of mood and related psychiatric disorders. All clinical data collected so far with regard to psilocybin or MDMA, which have reported positive outcomes for treating depression, anxiety, posttraumatic stress disorder, and drug or alcohol use disorders, have involved clinician-assisted intervention.

Outcomes 63

Outcomes 63

Science Daily - Stroke

JUNE 17, 2024

A new study has found that a novel discourse treatment improved the communication abilities of people with aphasia, a language disorder commonly resulting from stroke.

Strokes 61

Strokes Stroke 61

Cardiovascular Diabetology

JUNE 17, 2024

Elevated plasma glucose levels are common in patients suffering acute ischemic stroke (AIS), and acute hyperglycemia has been defined as an independent determinant of adverse outcomes. The impact of acute-to-c.

Strokes 59

Strokes Stroke Outcomes Diabetes 59

Medical Xpress - Cardiology

JUNE 17, 2024

The number of individuals in the U.S. who had chronic hypertension or chronic high blood pressure during pregnancy doubled between 2008 and 2021, while the prescribing and filling of antihypertensive medication during pregnancy remained low but stable at 60%, according to research published in Hypertension.

Blood Pressure 59

Blood Pressure Hypertension Research 59

Cardiovascular Diabetology

JUNE 17, 2024

Despite the high burden of obesity and Type 2 diabetes (T2DM) in the Middle East/West Asia region, the effect of weight change on the development of T2DM is poorly addressed. Therefore, we aimed to assess the.

Diabetes 59

Diabetes Obesity Research 59

HCPLive

JUNE 17, 2024

Analysis of NHANES data from 1999 to 2020 provides some evidence of diet quality improvement but highlights low rates of adults achieving ideal diet quality.

Diet 59

Diet 59

American Heart News - Heart News

JUNE 17, 2024

DALLAS, June 17, 2024 — About 40,000 people in the United States experience recurrent pericarditis, or inflammation of the sac-like structure that protects the heart, which can cause chest pain and may lead to fluid buildup around the heart muscle.

Pericarditis 53

Pericarditis Chest Pain 53

HCPLive

JUNE 17, 2024

Results revealed cDAPSA can help providers accurately measure the level of disease activity in patients and predict whether the patient will have radiographic progression.

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59

Journal of Cardiothoracic Surgery

JUNE 17, 2024

The surgical treatment strategy for aortic arch pathology with a shaggy aorta must be determined on a case-by-case basis because of the risk of catastrophic complications, such as brain infarction and spinal c.

Aortic 52

Aortic 52

HCPLive

JUNE 17, 2024

A study examines why patients with inflammatory arthritis might seek emergency department care over ambulatory care.

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59

Frontiers in Cardiovascular Medicine

JUNE 17, 2024

The incidence of atrial fibrillation (AF) is significantly higher in patients with pacemakers than in the general population, which could be due to patient characteristics and the diagnostic tool of the pacemaker in detecting atrial high-rate episodes and subclinical AF, but also to the pacemaker itself providing AF-promoting conditions. It is well known that high ventricular pacemaker burden increases the likelihood of AF occurrence.

Pacemaker 52

Pacemaker Atrial Fibrillation Electrophysiology 52

HCPLive

JUNE 17, 2024

These data may require large-scale studies to duplicate the findings, evaluating individuals with psoriasis who had PPM for IE antibiotic prophylaxis.

Pacemaker 59

Pacemaker 59

Frontiers in Cardiovascular Medicine

JUNE 17, 2024

BackgroundWhile Traditional Chinese Medicine (TCM) boasts an extensive historical lineage and abundant clinical expertise in addressing atherosclerosis, this field is yet to be penetrated adequately by bibliometric studies. This study is envisaged to evaluate the contemporary scenario of TCM in conjunction with atherosclerosis over the preceding decade while also identifying forthcoming research trends and emerging topics via the lens of bibliometric analysis.MethodsLiterature pertaining to TCM

Atherosclerosis 52

Atherosclerosis Research Article Circulation 52