HCPLive

JANUARY 13, 2025

The new definition uses both age and GFR without body surface area correction to determine the threshold value for hyperfiltration.

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Med Page Today

JANUARY 13, 2025

(MedPage Today) -- Dementia cases in the U.S. are expected to double in the next four decades, a new analysis suggested. In a racially and geographically diverse sample, the lifetime risk of dementia was estimated at 42% (95% CI 41-43) with incidence.

Dementia 91

Dementia 91

HCPLive

JANUARY 13, 2025

All participants with RP treated with OCU400 gene therapy achieved vision improvement or preservation at 2 years of the Phase 1/2 trial.

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ECG Guru

JANUARY 13, 2025

This ECG was sent to me by a friend, I don't know if he did it himself. The question was whether a heart attack can be recognized here. The patient is a 55-year-old man who has typical angina pectoris lasting more than 1 hour. What can you answer?

Heart Attack 73

Heart Attack Heart attacks Angina 73

HCPLive

JANUARY 13, 2025

Pediatric liver transplant centers with greater within-center variability in induction type had higher rates of 1-year rejection.

Transplant 82

Transplant Pediatrics 82

Science Daily - Stroke

JANUARY 13, 2025

Researchers have uncovered novel insights into how brain function disruptions related to cerebrovascular disease (CeVD) interact with Alzheimer's disease (AD) pathology to impact neurodegeneration and cognition in older adults.

Cerebrovascular Disease 71

Cerebrovascular Disease Research 71

Dr. Smith's ECG Blog

JANUARY 13, 2025

A 50-something male presented to triage with chest pain for one day. An ECG was recorded quickly before any further history or physical exam: What do you think? When I saw this (presented at a conference), I immediately thought it looked like Thype 1 Brugada phenocopy (in other words, Type 1 Brugada ECG pattern ). There is an rSR' in lead V1 without any spike of the R'-wave.

Chest Pain 74

Chest Pain Cardiac Arrest Ischemia Sudden Cardiac Death 74

Nature Reviews - Cardiology

JANUARY 13, 2025

Nature Reviews Cardiology, Published online: 14 January 2025; doi:10.1038/s41569-025-01122-5 In this Tools of the Trade article, Birch describes how extracellular vesicles can be engineered to deliver therapeutic microRNAs for the treatment of ischaemic stroke.

Stroke 62

Stroke Strokes Article 62

Frontiers in Cardiovascular Medicine

JANUARY 13, 2025

ObjectiveThis network meta-analysis was to compare the efficacy of different drugs on cardiac function, renal function, and clinical outcomes in patients with acute heart failure (AHF) accompanied by renal dysfunction.MethodsPubMed, EMBASE, Cochrane Library, and Web of Science were searched to screen all clinical trials of AHF between January 1st 2001 and March 31th 2024.

Heart Failure 52

Heart Failure Cardiac Function Outcomes 52

HCPLive

JANUARY 13, 2025

Hosts are joined by a registered dietitian and practicing endocrinologist to discuss dietitians' role in managing patients receiving incretin therapies.

Obesity 59

Obesity Diabetes 59

Frontiers in Cardiovascular Medicine

JANUARY 13, 2025

Electro-anatomical mapping (EAM) system has been shown as an alternative procedure to fluoroscopy for conduction system pacing (CSP) in patients with severe bradyarrhythmia, however its beneficial and harmful effects has not been assessed in a systematic review (SR). We sought to assess their safety, effectiveness and cost-effectiveness. A SR of the available scientific literature was conducted on the safety, effectiveness, and cost-effectiveness of CSP using EAM system vs. fluoroscopy in patien

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HCPLive

JANUARY 13, 2025

However, gout flare states of patient acceptable symptom state, low disease activity, or not achieving either were not associated with EQ-5D-3L or HAQ.

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Nature Reviews - Cardiology

JANUARY 13, 2025

Nature Reviews Cardiology, Published online: 14 January 2025; doi:10.1038/s41569-025-01117-2 In this Tools of the Trade article, Francesca Vacante and Andrew Baker describe a CRISPR-based approach to target the regulatory regions of non-coding RNAs.

Article 57

Article 57

HCPLive

JANUARY 13, 2025

In a recent study, participants reported worse patient care experience and staff responsiveness following the private equity acquisition of hospitals.

Patient Care 59

Patient Care Hospital 59

Frontiers in Cardiovascular Medicine

JANUARY 13, 2025

Cardiometabolic diseases (CMD) are leading causes of death and disability worldwide, with complex pathophysiological mechanisms in which inflammation plays a crucial role. This review aims to elucidate the molecular and cellular mechanisms within the inflammatory microenvironment of atherosclerosis, hypertension and diabetic cardiomyopathy. In atherosclerosis, oxidized low-density lipoprotein (ox-LDL) and pro-inflammatory cytokines such as Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TN

Atherosclerosis 52

Atherosclerosis Cardiomyopathy Diabetes Hypertension 52

DAIC

JANUARY 13, 2025

tim.hodson Mon, 01/13/2025 - 16:24 A new studyreports persistent disparities in outcomes for people with peripheral artery disease (PAD) and its more severe form, chronic limb-threatening ischemia (CLTI) in the United States. The study, Racial, Socioeconomic, and Geographic Disparities in Preamputation Vascular Care for Patients With Chronic Limb-Threatening Ischemia ," followed patients in the year leading up to their amputation.

Peripheral Arterial Disease 52

Peripheral Arterial Disease Outpatient Ischemia Vascular Care 52

American College of Cardiology

JANUARY 13, 2025

In this episode, Andrea Price, MS, AACC hosts Alex Tabone, PA-C, AACC, Alix Barnes, MD, and Sharon Dickinson, PA-C, FACC to share insights for serious conversations in the critical care trenches.

Critical Care 55

Critical Care Heart Disease Article 55

Heart BMJ

JANUARY 13, 2025

Background and aims N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a well-established biomarker in clinical practice, particularly for heart failure, but its role in predicting atrial fibrillation (AF) risk is not fully understood. This meta-analysis aimed to evaluate the association between NT-proBNP levels and AF incidence, and to explore the potential of NT-proBNP in enhancing AF risk prediction models.

Atrial Fibrillation 52

Atrial Fibrillation Biomarkers Heart Failure 52

Frontiers in Cardiovascular Medicine

JANUARY 13, 2025

AimsThis retrospective cohort study aimed to investigate the efficacy of dual-chamber left Bundle branch pacing (LBBP) as an alternative therapy for heart failure patients with complete left bundle branch block (CLBBB) and indications for defibrillator with cardiac resynchronization therapy (CRT-D).Methods34 patients met inclusion criteria were enrolled in the study.

Defibrillator 52

Defibrillator Heart Failure Echocardiogram Cardiac Function 52

Becker's Hospital Review - Cardiology

JANUARY 13, 2025

"CMS proposes Medicare and Medicaid coverage for implantable pulmonary artery pressure sensors to manage heart failure. Final decision to be published on Jan.

CMS 52

CMS Heart Failure Medicaid Medicare 52

Frontiers in Cardiovascular Medicine

JANUARY 13, 2025

BackgroundThe pharmacoinvasive (PhI) strategy is the standard-of-care for ST-elevation myocardial infarction (STEMI) patients when primary percutaneous coronary intervention (pPCI) is unfeasible. Optimal timing for post-fibrinolytic PCI (lysis-PCI) remains elusive. Therefore, this study aimed to assess the clinical and economic impacts of early vs. delayed lysis-PCI in patients with STEMI.MethodsThis retrospective cohort study included 1,043 STEMI patients classified by lysis-PCI timing.

Myocardial Infarction 52

Myocardial Infarction Outcomes STEMI Hospital 52

Becker's Hospital Review - Cardiology

JANUARY 13, 2025

MercyOne Siouxland Medical Center in Sioux City, Iowa, has indefinitely paused its open-heart surgery program.

Open-Heart Surgery 52

Open-Heart Surgery Hospital 52

Frontiers in Cardiovascular Medicine

JANUARY 13, 2025

BackgroundThe nomogram is a powerful and robust tool in disease risk prediction that summarizes complex variables into a visual model that is interpretable with a quantified risk probability. In the current study, a nomogram was developed to predict the occurrence of coronary artery lesions (CALs) among patients with Kawasaki disease (KD). This is especially valuable in the early identification of the risk of CALs, which will lead to proper diagnosis and treatment to reduce their associated comp

Hospital 52

Hospital Research 52

Becker's Hospital Review - Cardiology

JANUARY 13, 2025

"Vanderbilt Transplant Center sets world record with 174 heart transplants in 2024, including pediatric procedures.

Heart Transplant 52

Heart Transplant Transplant Pediatrics 52

Frontiers in Cardiovascular Medicine

JANUARY 13, 2025

Valvular heart disease (VHD) leading to inadequate hemodynamic circulation is a major cause of cardiovascular morbidity and mortality worldwide. Right ventricular-pulmonary artery (RVPA) coupling integrates the ability of RV contractility to adapt to increased pulmonary arterial afterload. If the right ventricle cannot adapt to the elevated afterload by increasing its contractile function, RV-PA uncoupling occurs.

Pulmonary 52

Pulmonary Heart Disease Circulation Outcomes 52

Becker's Hospital Review - Cardiology

JANUARY 13, 2025

The Women's Choice Award released its annual list of best hospitals Dec. 15, recognizing nearly 1,500 facilities nationwide for exceptional women's healthcare.

Hospital 52

Hospital Stroke Strokes 52

Med Page Today

JANUARY 13, 2025

(MedPage Today) -- For stroke patients undergoing mechanical thrombectomy, adjunctive intra-arterial thrombolytics fell short for further improving outcomes in two randomized trials. First, in POST-UK, there was a trend toward better odds of an.

Stroke 52

Stroke Strokes Outcomes 52

HCPLive

JANUARY 13, 2025

A study found many people with dementia live approximately 1 third of their remaining life expectancy in nursing homes.

Nursing 52

Nursing Dementia 52

DAIC

JANUARY 13, 2025

tim.hodson Mon, 01/13/2025 - 16:47 Jan. 13, 2025 R3 Vascular Inc., a medical device company dedicated totreating peripheral arterial disease (PAD), recently announceit received WCG Institutional Review Board (IRB) approval for the ELITE-BTK Pivotal Trial of its MAGNITUDEDrug Eluting Next Generation Bioresorbable Scaffold for Below-the-Knee Peripheral Arterial Disease (PAD).

Peripheral Arterial Disease 52

Peripheral Arterial Disease CMS Medicare Medicaid 52

HCPLive

JANUARY 13, 2025

A new study highlights notable obesity-associated disruptions of iron metabolism, with higher hemoglobin and serum ferritin levels in pre-obese and obese cohorts.

Obesity 52

Obesity 52

Frontiers in Cardiovascular Medicine

JANUARY 13, 2025

Diabetic cardiomyopathy (DCM) is one of the most prevalent and severe complications associated with diabetes mellitus (DM). The onset of DCM is insidious, with the symptoms being obvious only in the late stage. Consequently, the early diagnosis of DCM is a formidable challenge which significantly influences the treatment and prognosis of DCM. Thus, it becomes imperative to uncover innovative approaches to facilitate the prompt identification and diagnosis of DCM.

Cardiomyopathy 52

Cardiomyopathy Diabetes Research Biomarkers 52

HCPLive

JANUARY 13, 2025

These findings on asthma healthcare utilization resulted from the lack of a winter peak in RSV during the first months of the COVID-19 pandemic.

COVID-19 52

COVID-19 52

Frontiers in Cardiovascular Medicine

JANUARY 13, 2025

BackgroundConstipation frequently affects heart failure patients because of medication side effects and physiological effects of the condition. Although recent speculation suggests that comorbid constipation may affect cardiovascular disease onset and survival rates, this relationship remains unclear. We examined the effect of comorbid constipation on the survival of patients with heart failure.MethodsWe conducted a multicenter prospective cohort study (the Kochi YOSACOI study) of patients hospi

Heart Failure 52

Heart Failure Physiology Risk Factors Cardiovascular Disease 52

HCPLive

JANUARY 13, 2025

Panelists discuss how the ALIGN trial data inform the development and potential impact of emerging therapies for IgA nephropathy, particularly focusing on their efficacy in reducing proteinuria and addressing disease pathology.

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Frontiers in Cardiovascular Medicine

JANUARY 13, 2025

BackgroundAcute myocardial infarction (AMI), a subset of acute coronary syndrome, remains the major cause of mortality worldwide. Mitochondrial dysfunction is critically involved in AMI progression, and mitophagy plays a vital role in eliminating damaged mitochondria. This study aimed to explore mitophagy-related biomarkers and their potential molecular basis in AMI.MethodsAMI datasets (GSE24519 and GSE34198) from the Gene Expression Omnibus database were combined and the batch effects were remo

Myocardial Infarction 52

Myocardial Infarction Biomarkers Research 52

HCPLive

JANUARY 13, 2025

Panelists discuss how the ALIGN trial data inform the development and potential impact of emerging therapies for IgA nephropathy, particularly focusing on their efficacy in reducing proteinuria and addressing disease pathology.

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American College of Cardiology

JANUARY 13, 2025

New multi-society Appropriate Use Criteria (AUC) published in JACC focus on cardiac implantable electronic devices (CIEDs), specifically implantable cardioverter-defibrillators (ICDs), cardiac resynchronization therapy (CRT), and pacing. The updated criteria address a broad spectrum of clinical scenarios and key areas where new data are available or new procedures and technologies have resulted in changes in practice since the original AUC on CIEDs were published in 2013.

Defibrillator 45

Defibrillator Technology Article 45