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(MedPage Today) -- Dementia cases in the U.S. are expected to double in the next four decades, a new analysis suggested. In a racially and geographically diverse sample, the lifetime risk of dementia was estimated at 42% (95% CI 41-43) with incidence.
ObjectiveThis network meta-analysis was to compare the efficacy of different drugs on cardiac function, renal function, and clinical outcomes in patients with acute heart failure (AHF) accompanied by renal dysfunction.MethodsPubMed, EMBASE, Cochrane Library, and Web of Science were searched to screen all clinical trials of AHF between January 1st 2001 and March 31th 2024.
New multi-society Appropriate Use Criteria (AUC) published in JACC focus on cardiac implantable electronic devices (CIEDs), specifically implantable cardioverter-defibrillators (ICDs), cardiac resynchronization therapy (CRT), and pacing. The updated criteria address a broad spectrum of clinical scenarios and key areas where new data are available or new procedures and technologies have resulted in changes in practice since the original AUC on CIEDs were published in 2013.
Cardiothoracic and Vascular Surgeons is proud to share that several of our physicians received important accolades closing out 2024 and ushering in 2025. For several years, our team of cardiothoracic and vascular surgeons has been humbled to receive recognition as Texas Monthly Super Doctors and Austin Monthly Top Doctors.
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Stroke, Ahead of Print. Stroke mimics and chameleons remain a major challenge to the clinician and clinical investigator. Misdiagnosis of stroke can result in significant harm to our patients, as well as unnecessary financial costs to the health care systems internationally. The approach to stroke mimics and chameleons has evolved over time with the development of clinical scales and technology.
Researchers have uncovered novel insights into how brain function disruptions related to cerebrovascular disease (CeVD) interact with Alzheimer's disease (AD) pathology to impact neurodegeneration and cognition in older adults.
This ECG was sent to me by a friend, I don't know if he did it himself. The question was whether a heart attack can be recognized here. The patient is a 55-year-old man who has typical angina pectoris lasting more than 1 hour. What can you answer?
Nature Reviews Cardiology, Published online: 14 January 2025; doi:10.1038/s41569-025-01117-2 In this Tools of the Trade article, Francesca Vacante and Andrew Baker describe a CRISPR-based approach to target the regulatory regions of non-coding RNAs.
Hosts are joined by a registered dietitian and practicing endocrinologist to discuss dietitians' role in managing patients receiving incretin therapies.
In this episode, Andrea Price, MS, AACC hosts Alex Tabone, PA-C, AACC, Alix Barnes, MD, and Sharon Dickinson, PA-C, FACC to share insights for serious conversations in the critical care trenches.
Nature Reviews Cardiology, Published online: 14 January 2025; doi:10.1038/s41569-025-01122-5 In this Tools of the Trade article, Birch describes how extracellular vesicles can be engineered to deliver therapeutic microRNAs for the treatment of ischaemic stroke.
However, gout flare states of patient acceptable symptom state, low disease activity, or not achieving either were not associated with EQ-5D-3L or HAQ.
AimsThis retrospective cohort study aimed to investigate the efficacy of dual-chamber left Bundle branch pacing (LBBP) as an alternative therapy for heart failure patients with complete left bundle branch block (CLBBB) and indications for defibrillator with cardiac resynchronization therapy (CRT-D).Methods34 patients met inclusion criteria were enrolled in the study.
BackgroundThe pharmacoinvasive (PhI) strategy is the standard-of-care for ST-elevation myocardial infarction (STEMI) patients when primary percutaneous coronary intervention (pPCI) is unfeasible. Optimal timing for post-fibrinolytic PCI (lysis-PCI) remains elusive. Therefore, this study aimed to assess the clinical and economic impacts of early vs. delayed lysis-PCI in patients with STEMI.MethodsThis retrospective cohort study included 1,043 STEMI patients classified by lysis-PCI timing.
"CMS proposes Medicare and Medicaid coverage for implantable pulmonary artery pressure sensors to manage heart failure. Final decision to be published on Jan.
BackgroundThe nomogram is a powerful and robust tool in disease risk prediction that summarizes complex variables into a visual model that is interpretable with a quantified risk probability. In the current study, a nomogram was developed to predict the occurrence of coronary artery lesions (CALs) among patients with Kawasaki disease (KD). This is especially valuable in the early identification of the risk of CALs, which will lead to proper diagnosis and treatment to reduce their associated comp
Valvular heart disease (VHD) leading to inadequate hemodynamic circulation is a major cause of cardiovascular morbidity and mortality worldwide. Right ventricular-pulmonary artery (RVPA) coupling integrates the ability of RV contractility to adapt to increased pulmonary arterial afterload. If the right ventricle cannot adapt to the elevated afterload by increasing its contractile function, RV-PA uncoupling occurs.
(MedPage Today) -- For stroke patients undergoing mechanical thrombectomy, adjunctive intra-arterial thrombolytics fell short for further improving outcomes in two randomized trials. First, in POST-UK, there was a trend toward better odds of an.
The Women's Choice Award released its annual list of best hospitals Dec. 15, recognizing nearly 1,500 facilities nationwide for exceptional women's healthcare.
A new study highlights notable obesity-associated disruptions of iron metabolism, with higher hemoglobin and serum ferritin levels in pre-obese and obese cohorts.
ABSTRACT Background Atrioventricular block (AVB) is a cardiac conduction disorder that can lead to significant clinical outcomes, particularly in resource-limited and conflict-affected regions. In Syria, healthcare infrastructure has been severely impacted by ongoing conflict, potentially affecting the prevalence and management of AVB. Methods We conducted a cross-sectional study at Tishreen University Hospital in Latakia, Syria, with patients >40 who presented to the emergency department (ED
Panelists discuss how the ALIGN trial data inform the development and potential impact of emerging therapies for IgA nephropathy, particularly focusing on their efficacy in reducing proteinuria and addressing disease pathology.
ABSTRACT Ryanodine receptor 2 (RyR2) protein, a calcium ion release channel in the sarcoplasmic reticulum (SR) of myocardial cells, plays a crucial role in regulating cardiac systolic and diastolic functions. Mutations in RyR2 and its dysfunction are implicated in various congenital heart diseases (CHDs). Studies have shown that mutations in the RYR2 gene, which encodes the RyR2 protein, are linked to several cardiac arrhythmias, including catecholaminergic polymorphic ventricular tachycardia (C
Panelists discuss how the ALIGN trial data inform the development and potential impact of emerging therapies for IgA nephropathy, particularly focusing on their efficacy in reducing proteinuria and addressing disease pathology.
ABSTRACT Background Atrial fibrillation (AF) is the most common arrhythmia worldwide. However, data regarding readmissions following index admission for AF in the developing world are not well described. This study assessed the rate, predictors, and trends of 6-month readmission after index admission for AF in Syria. Methods We included adult patients who had an index admission with AF to Latakia's tertiary center between July 2021 and November 2023.
Hypertension, Ahead of Print. BACKGROUND:Blood pressure (BP) time in target range (TTR) reflects the proportion of time that BP measurement is within a specified target range. We aim to summarize the evidence for relationships between TTR and adverse health outcomes.METHODS:Seven databases were searched. After quality assessment and data extraction, meta-analyses were performed to generate pooled estimates of the association (hazard ratios) between TTR and health outcomes.
ABSTRACT We encountered a single case in which a transition between orthodromic reciprocating tachycardia with a concealed nodoventricular pathway and atrioventricular nodal reentrant tachycardia with a bystander nodoventricular pathway was observed.
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