Mon.Oct 21, 2024

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New guideline: Preventing a first stroke may be possible with screening, lifestyle changes

American Heart News - Stroke News

Guideline Highlights: Each year in the U.S., over half a million people have a first stroke; however, up to 80% of strokes may be preventable. The new primary prevention of stroke guideline from the American Stroke Association urges health care.

Strokes 143
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Kidney Compass: Navigating Clinical Trials

HCPLive

Kidney Compass: Navigating Clinical Trials is a multimedia podcast from HCPLive hosted by Brendon Neuen, MBBS, PhD, and Shikha Wadhwani, MD, MS, aimed at exploring the latest in clinical trials and updates in nephrology.

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A Win

Dr. Malcolm Kendrick

21st October 2024 Finally, the dust settles. Zoë and I won our case against the Mail on Sunday. The judgement came out a few weeks ago, but the legal wrangling continued – and still continues. The Mail on Sunday did print an apology. Legally, they do not have to print an apology, but they did, which says something. There is still a statement in open court to come (SIOC).

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Sodium-glucose cotransporter 2 inhibitors and cardiovascular events among patients with type 2 diabetes and low-to-normal body mass index: a nationwide cohort study

Cardiovascular Diabetology

Patients with low-to-normal body mass index (BMI; < 25.0 kg/m2) were underrepresented in major randomized controlled trials on sodium-glucose cotransporter 2 (SGLT2) inhibitors for type 2 diabetes. The present st.

Diabetes 120
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Stroke Prevention Guideline Adds Recs for GLP-1 Drugs, Gender-Affirming Care

Med Page Today

(MedPage Today) -- The American Heart Association and the American Stroke Association updated guidelines for the primary prevention of stroke, emphasizing primary care screening, lifestyle management, and risk factor control. The guideline, published.

Stroke 105
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New guideline: Preventing a first stroke may be possible with screening, lifestyle changes

Science Daily - Heart Disease

Updated clinical recommendations, including lifestyle changes, prevention strategies and treatment options, to reduce the risk of a first stroke have been outlined in a new guideline.

Stroke 106
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What’s New in Ultrasound Tech – 2025 Edition

Cassling

While you weren’t looking, a lot has been happening in the field of ultrasound! New technologies, new workflows, new best practices. Over just a few short years, the potential uses of ultrasound have grown exponentially, and that means exciting things for you and your imaging team. Join us as we take a look at the latest developments in ultrasound you may have missed, even if you’re working on equipment that’s just a couple years old.

More Trending

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Somatic GNAQ, CTNNB1, and CACNA1C Mutations in Cat Aldosterone-Secreting Tumors

Hypertension Journal

Hypertension, Ahead of Print. BACKGROUND:Primary aldosteronism (PA) is a common cause of human hypertension. Somatic mutations inKCNJ5,CACNA1D,ATP1A1, andATP2B3are found in at least 80% of aldosterone-producing adenomas, which cause unilateral PA in humans. Somatic mutations have been identified infrequently in 7 other genes; few of these were known to play a role in aldosterone secretion before the discovery of their mutations.

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GALE: Pegcetacoplan Achieves Increasing Efficacy in Subfoveal Geographic Atrophy

HCPLive

Pegcetacoplan injection showed increased benefit for subfoveal GA, with as few as 6 injections, over 3 years in the GALE extension trial.

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Intermountain 1st in US to perform aortic aneurysm procedure

Becker's Hospital Review - Cardiology

A vascular surgeon at Salt Lake City-based Intermountain Health has become the first in the U.S. to use the Gore EXCLUDER Thoracoabdominal Branch Endoprosthesis device for the treatment of an aortic aneurysm outside of a clinical trial.

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How Artificial Intelligence is Being Used in Lung Imaging, with Rachel Eddy, PhD

HCPLive

In the most recent Lungcast, Rachel Eddy, PhD, joined host Al Rizzo, MD, to speak to listeners about the current and future uses of AI in lung imaging.

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Effect of ertugliflozin on left ventricular function in type 2 diabetes and pre-heart failure: the Ertu-GLS randomized clinical trial

Cardiovascular Diabetology

The therapeutic effects of ertugliflozin, a sodium-glucose cotransporter 2 inhibitor, on cardiovascular outcome are not fully understood. This study aimed to evaluate the efficacy and safety of ertugliflozin o.

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Alitretinoin Superior to UV Therapy in Rapid Improvements to Chronic Hand Eczema

HCPLive

These data suggest more immediate benefits to alitretinoin, though ultraviolet therapy was shown to be cost-effective after 10 years of use.

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Evaluation of the Steno Type 1 Risk Engine in predicting cardiovascular events in an ethnic mixed population of type 1 diabetes mellitus and its association with chronic microangiopathy complications

Cardiovascular Diabetology

The Steno Type 1 Risk Engine (ST1RE) was developed to aid clinical decisions in primary prevention for individuals with type 1 diabetes (T1D), as existing cardiovascular (CV) risk models for the general popula.

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Adding Depression to Cardiovascular Risk Scores Offers Minimal Predictive Benefit

HCPLive

A study found that adding depression to Life's Essential 8 provides minimal improvements in predicting cardiovascular and all-cause mortality risk.

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Double innominate vein in a case with double aortic arch: a case report

Journal of Cardiothoracic Surgery

Double aortic arch (DAA) is a type of vascular ring, causing stridor and dysphagia owing to compression of the trachea and esophagus. In contrast, double innominate veins, which is a relatively rare venous ano.

Aortic 52
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Materialise Acquires FEops to Help Expand Cardiovascular Capabilities

DAIC

tim.hodson Mon, 10/21/2024 - 15:52 Earlier this year, Materialise, a global supplier of 3D printing software and services, acquired FEops , a Belgian company that develops AI-driven simulation technology to improve procedure efficiency and clinical outcomes for structural heart interventions. The acquisition will allow Materialise to expand its cardiovascular solutions with predictive simulation capabilities, advancing the personalized treatment of patients with heart diseases.

Anatomy 52
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Risk stratification by renal function and NYHA class in patients with hypotension initiated on sacubitril/valsartan: a retrospective cohort study from 17 centres in Japan

Open Heart

Background Patients with heart failure exhibiting low systolic blood pressure (SBP) have a poor prognosis. Sacubitril/valsartan reduces cardiovascular events; however, its use in patients with low SBP has not been fully examined. Therefore, in this study, we aimed to investigate the association between baseline SBP and adverse events (AEs) in patients starting sacubitril/valsartan therapy using data from a real-world registry in Japan.

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BSC Launches Next Gen of Cardiac Mapping for Pulsed Field Ablation System

DAIC

Boston Scientific has received U.S. FDA approval for the navigation-enabled FARAWAVE NAV Ablation Catheter for the treatment of paroxysmal atrial fibrillation and FDA 510(k) clearance for the new FARAVIEW Software, which will combine to provide visualization for cardiac ablation procedures with the FARAPULSE Pulsed Field Ablation System. tim.hodson Mon, 10/21/2024 - 11:41 Oct. 18, 2024 — Boston Scientific Corp. recently announced it has received U.S.

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SBC Scientific Publication Award 2024 Held at the 79th Brazilian Congress of Cardiology

International Journal of Cardiovascular Sciences

On September 21, 2024, during the 79th Brazilian Congress of Cardiology in Brasília, we celebrated excellence in research and publication with the SBC Scientific Publication Award for the Family ABC journals! During this ceremony, we honored the best original articles, the most cited articles, and the most active reviewers of the journals ABC Cardiol, IJCS, ABC Imagem, and ABC HF.

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HRS Creates New Advocacy Organization

DAIC

tim.hodson Mon, 10/21/2024 - 11:24 Oct. 18, 2024 — The Heart Rhythm Society (HRS) Board of Trustees unanimously approved the formation of Heart Rhythm Advocates , a new, shared vision, cause-related nonprofit 501(c)(4) advocacy organization to complement the primary 501(c)(3) nonprofit structure of the HRS.  This announcement comes at a time when atrial fibrillation (AF) is on the rise, affecting more than 10.5 million Americans. 1 A growing patient population, increase in electrophysiology pr

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Gildeuretinol Shows Promise in Slowing Geographic Atrophy Progression

HCPLive

Decreasing Vitamin A dimerization could be a potential mechanism to treat geographic atrophy, according to results from the two-year SAGA study at AAO 2024.

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Greater Baseline TR Associated With Worse Outcomes After TAVR or Mitral TEER

American College of Cardiology

Patients with moderate or severe tricuspid regurgitation (TR) prior to undergoing TAVR or mitral transcatheter edge-to-edge repair (TEER), when compared to patients with no or mild TR, were associated with worse health status and clinical outcomes, according to a study published in JACC: Cardiovascular Interventions.

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Oral Semaglutide Reduces MACE Risk in People With Type 2 Diabetes and CVD

HCPLive

Novo Nordisk will present more detailed data in 2025 and plans to file for an expanded label for Rybelsus for this population.

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ACC CardiaCast: Pulse Check: What’s New in Hypertension Management for the Pharmacist CV Team Professional?

American College of Cardiology

In this episode, Andrea Price, MS, AACC hosts Lydia Tran, PharmD, BCPS and Sushma Dey, PharmD, BCACP to discuss the role of the pharmacists on the care team for hypertension management.

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Joel A. Pearlman, MD, PhD: Phase 2a Data on Oral RZ402 for DME

HCPLive

At AAO 2024, Pearlman discusses how an innovative oral approach may provide an alternative pathway to existing treatments for DME.

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Efficacy and Safety of Olezarsen in Managing Hypertriglyceridemia: Insights From the BRIDGE–TIMI 73a Trial

American College of Cardiology

Hypertriglyceridemia (HTG) remains a significant clinical challenge because of its association with increased cardiovascular (CV) risk and acute pancreatitis.

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Treatment Flexibility While on Abrocitinib in Atopic Dermatitis (JADE REGIMEN)

HCPLive

Medical experts review the data on the use of oral JAK inhibitors for maintenance and rescue treatments in atopic dermatitis.

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Intra- and Post-Operative Management of Conduits for CABG: Key Points

American College of Cardiology

The following are key points to remember from a European clinical consensus statement on intra-operative and post-operative management of conduits for coronary artery bypass grafting (CABG).

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Clinical Quiz: ACG Guidelines for Treating Helicobacter Pylori Infection

HCPLive

Test your knowledge of the 2024 American College of Gastroenterology H. pylori management guidelines with this clinical quiz!

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Intensive Early and Sustained Lowering of Non–HDL-C

American College of Cardiology

What is the relationship between non–high-density lipoprotein cholesterol (non–HDL-C) levels after myocardial infarction (MI) and risk of adverse outcomes?

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Face Masking Did Not Affect Endophthalmitis Rates After Anti-VEGF Injections

HCPLive

Endophthalmitis incidence remained similar between face masking and non-face masking groups during anti-VEGF treatment.

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Arm Position and BP Readings

American College of Cardiology

How important is proper arm position in obtaining accurate blood pressure (BP) measurements?

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Future Outlook for Atopic Dermatitis Treatments

HCPLive

Medical experts share their final thoughts on the future of atopic dermatitis treatment with oral systemic agents.

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Deubiquitinase USP47 ameliorates cardiac hypertrophy through reducing protein O-GlcNAcylation

Journal of Cardiovascular Pharmacology

Cardiac hypertrophy is a crucial risk factor for heart failure when the heart is confronted with physiological or pathological stimuli. The ubiquitin-proteasome system (UPS) plays a critical role in the pathogenesis of cardiac hypertrophy. However, as a key component of the UPS, the role of deubiquitinating enzymes (DUBs) in cardiac hypertrophy is not well understood.

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Percutaneous biopsy and removal of a pacemaker lead-attached mass of unclear nature

HeartRhythm

The most common masses on pacemaker leads are thrombi and infective endocarditis(1). Neoplasms attached to pacemaker leads are less frequently encountered. The mainstay treatment of infective endocarditis and large masses (particularly those that do not respond to medical therapy) is lead extraction. With large masses a surgical approach is typically pursued(1).

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Efficacy and limitation of nonparoxysmal atrial fibrillation ablation in patients with heart failure with preserved ejection fraction

Journal of Cardiovascular Electrophysiology

Abstract Introduction Catheter ablation for atrial fibrillation (AF) reduces heart failure (HF) hospitalization in patients with HF with preserved ejection fraction (HFpEF). However, the long-term outcomes and subclinical HF after nonparoxysmal AF ablation in HFpEF patients have not been fully evaluated. Methods and Results One-hundred-ninety nonparoxysmal AF patients with left ventricular ejection fraction ≥50% who underwent first-time AF ablation were studied.