Mon.Feb 12, 2024

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Dementia Predicted 10 Years Before Diagnosis

Med Page Today

(MedPage Today) -- Blood protein profiles predicted future dementia in healthy adults, a large longitudinal study showed. Blood samples from over 50,000 people in the U.K. Biobank showed that four proteins -- glial fibrillary acidic protein.

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Century of progress sets stage for future scientific advances in cardiovascular health

American Heart News - Heart News

Embargoed until 4 a.m. CT/5 a.m. ET Monday, Feb. 12, 2024 DALLAS, Feb. 12, 2024 — Dramatic advances in the understanding and treatment of cardiovascular diseases have saved millions of lives in the 100 years since the founding in 1924 of the American.

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Rapid Weight Loss a Diabetic Retinopathy Risk?

Med Page Today

(MedPage Today) -- While rapid weight-loss with bariatric surgery or drugs might temporarily worsen diabetic retinopathy as blood sugar levels are rapidly corrected, the low overall risk likely doesn't outweigh the benefits of weight loss, according.

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DNA methylation risk score for type 2 diabetes is associated with gestational diabetes

Cardiovascular Diabetology

Gestational diabetes mellitus (GDM) and type 2 diabetes mellitus (T2DM) share many pathophysiological factors including genetics, but whether epigenetic marks are shared is unknown. We aimed to test whether a.

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Can hydrogels help mend a broken heart?

Science Daily - Heart Disease

You can mend a broken heart this valentine s day now that researchers invented a new hydrogel that can be used to heal damaged heart tissue and improve cancer treatments.

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Heart disease risk factors in women highlight need for increased awareness, prevention

American Heart News - Heart News

Statement Highlights: The new scientific statement highlights heart disease as the leading cause of death for women and emerging evidence that has identified several gender-specific risk factors for heart disease in women, including complications.

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Electroacupuncture Effectively Treats Gouty Arthritis

HCPLive

Electroacupuncture demonstrates superior analgesic effects and the ability to lower serum uric acid in patients with acute gouty arthritis when compared to conventional medication options.

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FDA Approves Budesonide Oral Suspension (Eohilia) for Eosinophilic Esophagitis

HCPLive

The decision makes budesonide oral suspension (Eohilia) the first and only FDA-approved oral therapy for patients ≥ 11 years of age with eosinophilic esophagitis.

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Free-breathing DL vs. Breath-hold Cardiac MRI Sequences in Ischemic Heart Disease

DAIC

85-year-old patient with ischemic heart disease, who underwent cardiac MRI at 3 T. A. Short-axis image from standard cine balanced SSFP breath-hold sequence. B. Short-axis image from free-breathing accelerated cine sequence with deep-learning reconstruction. Images show normal appearance of left ventricular myocardium. milla1cf Mon, 02/12/2024 - 15:06 February 12, 2024 — According to the American Journal of Roentgenology (AJR) , free-breathing cine-deep learning (DL) may yield reliable left ven

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Iron Deficiency More Common in Preterm Infants Not Fed with Breast Milk

HCPLive

HCPLive is a comprehensive clinical news and information portal that provides physicians with up-to-date specialty and disease-specific resources designed to help them provide better care to patients. At HCPLive, you will find breaking news, video interviews with physician experts, in-depth conference coverage, finance and practice management updates, insight and analysis from physician contributors, and more.

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A Conversation on Healthy Running Habits, Biomechanics, and Choosing the Right Footwear with Dr. Heather Vincent

Physiologically Speaking

Author’s note: the first 45 minutes of this episode is a discussion between myself and Dr. Vincent about results of my gait analysis. Skip to 45 minutes if you don’t want to listen to this and prefer to hear about healthy running habits and footwear. Dr.

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FDA Reviewers Skeptical on TriClip for Tricuspid Regurgitation

Med Page Today

(MedPage Today) -- FDA staff questioned the evidence for clinical benefit with the TriClip G4 transcatheter edge-to-edge repair (TEER) system for severe tricuspid regurgitation (TR) in documents released ahead of the agency's Circulatory System.

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A standard blood test can predict a heart attack

Science Daily - Heart Disease

Using the results of a standard blood test and an online tool, you can find out if you are at increased risk of having a heart attack within six months.

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Hemoglobin Levels Associated with Bone Density in Patients with T2D

HCPLive

A new analysis cites relatively high hemoglobin levels as a protective factor for bone quality in patients with type 2 diabetes.

Diabetes 105
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How a standard blood test can predict a heart attack

Medical Xpress - Cardiology

Using the results of a standard blood test and an online tool, you can find out if you are at increased risk of having a heart attack within six months. The tool has been developed by a research group at Uppsala University in the hope of increasing patients' motivation to change their lifestyles.

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Vomiting, Diarrhea, and "Bubbles in my Chest"

Dr. Smith's ECG Blog

A 60-something complained of vomiting, diarrhea overnight, and "bubbles in my chest" that started just prior to calling 911. He had this ECG recorded prehospital: Smith interpretation: There are hyperacute T-waves in III and aVF, and reciprocal STD in aVL with a reciprocally inverted T-wave in aVL. There are also hyperacute T-waves in V3 and V4. There is STD in V1 and V2.

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Clinical relevance of transcranial Doppler in a cardiac surgery setting: embolic load predicts difficult separation from cardiopulmonary bypass

Journal of Cardiothoracic Surgery

During cardiac surgery, transcranial Doppler (TCD) represents a non-invasive modality that allows measurement of red blood cell flow velocities in the cerebral arteries. TCD can also be used to detect and moni.

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Cardiovascular Outcomes in GRADE (Glycemia Reduction Approaches in Type 2 Diabetes: A Comparative Effectiveness Study)

Circulation

Circulation, Ahead of Print. BACKGROUND:Cardiovascular disease is a major cause of morbidity and mortality in patients with type 2 diabetes. The effects of glucose-lowering medications on cardiovascular outcomes in individuals with type 2 diabetes and low cardiovascular risk are unclear. We investigated cardiovascular outcomes by treatment group in participants randomly assigned to insulin glargine, glimepiride, liraglutide, or sitagliptin, added to baseline metformin, in GRADE (Glycemia Reducti

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Young adult with left ventricular dysfunction

Heart BMJ

Clinical introduction A patient in their 30s had been diagnosed with peripartum cardiomyopathy, pulmonary oedema, with severe left ventricular dysfunction at the seventh month of gestation in the third pregnancy in their late 20s. The patient had pregnancy-induced hypertension and hypothyroidism and was treated accordingly. The patient was managed medically and was referred to us in view of worsening symptoms with severe left ventricular dysfunction and moderate aortic regurgitation.

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The American Heart Association at 100: A Century of Scientific Progress and the Future of Cardiovascular Science: A Presidential Advisory From the American Heart Association

Circulation

Circulation, Ahead of Print. In 1924, the founders of the American Heart Association (AHA) envisioned an international society focused on the heart and aimed at facilitating research, disseminating information, increasing public awareness, and developing public health policy related to heart disease. This presidential advisory provides a comprehensive review of the past century of cardiovascular and stroke science, with a focus on the AHA’s contributions, as well as informed speculation about th

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Study shows salt substitutes help to maintain healthy blood pressure in older adults

Medical Xpress - Cardiology

The replacement of regular salt with a salt substitute can reduce incidences of hypertension, or high blood pressure, in older adults without increasing their risk of low blood pressure episodes, according to a recent study in the Journal of the American College of Cardiology. People who used a salt substitute had a 40% lower incidence and likelihood of experiencing hypertension compared to those who used regular salt.

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Non-alcoholic fatty liver disease biomarkers estimate cardiovascular risk based on coronary artery calcium score in type 2 diabetes: a cross-sectional study with two independent cohorts

Cardiovascular Diabetology

Studies have demonstrated that coronary artery calcification on one hand and non-alcoholic fatty liver disease (NAFLD) on the other hand are strongly associated with cardiovascular events. However, it remains.

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The slowly evolving truth about heart disease and women

Medical Xpress - Cardiology

A century ago, so little was known about heart disease that people who had it resigned themselves to years of bed rest or, worse, an early death. Even less was known about how heart disease affected women—because nobody thought it did.

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Effect of on-pump vs. off-pump coronary artery bypass grafting in patients with non-dialysis-dependent severe renal impairment: propensity-matched analysis from the UK registry dataset

Frontiers in Cardiovascular Medicine

Introduction On-pump coronary artery bypass (ONCABG) grafting in patients with a pre-existing poor renal reserve is known to carry significant morbidity and mortality. There is limited controversial evidence on the benefit of off-pump coronary artery bypass (OPCABG) grafting in these high-risk groups of patients. We compared early clinical outcomes in propensity-matched cohorts of patients with non-dialysis-dependent pre-operative severe renal impairment undergoing OPCABG vs.

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Genomic study sheds light on immune microenvironment in transplanted pediatric hearts

Medical Xpress - Cardiology

Pediatric heart transplantation has long been hailed as a life-saving intervention for children suffering from end-stage heart failure. While the procedure offers hope, the long-term outcomes for these young patients remain suboptimal due to allograft rejection and graft failure.

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Case report: Primary pericardial angiosarcoma, a rare cause of cardiac tamponade

Frontiers in Cardiovascular Medicine

Primary pericardial angiosarcoma is a rare malignancy of the pericardium with variable clinical features and imaging characteristics. Herein, we report a case of histopathologically confirmed pericardial angiosarcoma in a 66-year-old man. The patient developed cardiac tamponade in a short time period. The transthoracic echocardiography showed the presence of multiple irregular echodensities, heterogeneous in echogenicity, encasing the apex of both ventricles in the pericardial space, initially m

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Coronary Angiography, Intravascular Ultrasound, and Optical Coherence Tomography in the Guidance of Percutaneous Coronary Intervention: A Systematic Review and Network Meta-Analysis.

Circulation

Circulation, Ahead of Print. BACKGROUND:Results from multiple randomized clinical trials comparing outcomes after intravascular ultrasound (IVUS)– and optical coherence tomography (OCT)–guided percutaneous coronary intervention (PCI) with invasive coronary angiography (ICA)–guided PCI as well as a pivotal trial comparing the 2 intravascular imaging (IVI) techniques have provided mixed results.METHODS:Major electronic databases were searched to identify eligible trials evaluating at least 2 PCI g

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Efficacy and safety of tongxinluo capsule for angina pectoris of coronary heart disease: an overview of systematic reviews and meta-analysis

Frontiers in Cardiovascular Medicine

Background Tongxinluo capsule (TXLC) is a common drug for treating angina pectoris of coronary heart disease (CHD). In recent years, many systematic reviews (SRs) and meta-analyses (MAs) have reported the efficacy and safety of TXLC for improving angina symptoms in patients with CHD. We aimed to comprehensively evaluate the existing SRs and MAs of TXLC in treating angina pectoris of CHD, summarize the evidence quality, and provide scientific evidence and recommendations.

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Leesha Ellis-Cox: Steps to Closing the Bipolar Disorder Diagnosis Gap for Blacks

HCPLive

In an interview with HCPLive, Leesha Ellis-Cox broke down factors contributing to the bipolar disorder diagnosis gap for African Americans.

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Polygenic risk score predicts all-cause death in East Asian patients with prior coronary artery disease

Frontiers in Cardiovascular Medicine

Introduction Coronary artery disease (CAD) is a highly heritable and multifactorial disease. Numerous genome-wide association studies (GWAS) facilitated the construction of polygenic risk scores (PRS) for predicting future incidence of CAD, however, exclusively in European populations. Furthermore, identifying CAD patients with elevated risks of all-cause death presents a critical challenge in secondary prevention, which will contribute largely to reducing the burden for public healthcare.

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Pursuing Lung Cancer Precision Medicine, with Jonathan Spicer, MD, PhD

HCPLive

The prominent clinical investigator joins to discuss adjuvant and neoadjuvant care research, as well as the application of biomarkers in personalized care.

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Treatment of coronary lesions with a novel crystalline sirolimus-coated balloon

Frontiers in Cardiovascular Medicine

Background There is mounting data supporting the use of drug-coated balloons (DCB) not only for treatment of in-stent restenosis (ISR), but also in native coronary artery disease. So far, paclitaxel-coated balloons represented the mainstay DCBs. The SeQuent® crystalline sirolimus-coated balloon (SCB) (B.Braun Medical Inc, Germany) represents a novel DCB, which allows a sustained release of the limus-drug.

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Association of Black Cardiologists enlists clinicians for new hypertension certification

Becker's Hospital Review - Cardiology

The Association of Black Cardiologists is recruiting clinicians for a new certification program it launched in December related to hypertension management. The aim is to increase culturally conscious care for patient populations that are more likely to be diagnosed with the condition and experience adverse outcomes from it.

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Takotsubo syndrome and atrial myxoma—identifying a new trigger: a case report

Frontiers in Cardiovascular Medicine

Takotsubo syndrome (TTS) is a rare cardiomyopathy, but its prevalence is increasing due to the greater availability of diagnostic tools, whose pathophysiology is unknown; however, the evidence points to an excess of catecholamines that ends up generating cardiac stunning. The cause of excessive sympathetic discharge is multifactorial, and some tumors may be related to their origin.

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Multivessel Immediate vs. Staged Revascularization in Acute Myocardial Infarction: The MULTISTARS AMI Trial

American College of Cardiology

The MULTISTARS AMI (MULTivessel Immediate versus STAged RevaScularization in Acute Myocardial Infarction) trial compared immediate versus delayed percutaneous coronary intervention (PCI) of nonculprit lesions in patients with ST-segment elevation myocardial infarction (STEMI) who underwent successful primary PCI of the culprit lesion.

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Greater Risk of Major Congenital Malformations Among Children Born to Mothers with Asthma

HCPLive

This review and meta-analysis yielded results which confirmed prior data on maternal asthma and neonatal outcomes, in addition to establishing several new findings.

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The top states, hospitals for coronary intervention, per Healthgrades

Becker's Hospital Review - Cardiology

Healthgrades released its rankings of the top hospitals for coronary intervention; only 10 states met the requirements to have hospitals ranked in the speciality.