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Nature Reviews Cardiology, Published online: 07 February 2025; doi:10.1038/s41569-025-01131-4 Hypertension is the leading cause of death globally but has low rates of diagnosis and treatment. In this Review, Dhaun and colleagues discuss the reasons for poor control of hypertension, such as therapeutic inertia and poor patient adherence, as well as novel pharmacological approaches to blood pressure lowering.
Cardiovascular diseases are the most lethal diseases worldwide, of which myocardial infarction is the leading cause of death. After myocardial infarction, in order to ensure normal blood supply to the heart, the remaining cardiomyocytes compensate for the loss of cardiomyocytes mainly by working at high capacity rather than by proliferating to produce new cardiomyocytes.
The future of medical imaging is about connection. Today’s healthcare challenges demand platforms that unify radiology, cardiology, digital pathology, genomics, and beyond into a seamless enterprise ecosystemmoving past the era of standalone systems and isolated workflows. A complete enterprise imaging solution allows us to move closer to an improved multidisciplinary collaboration, and a more comprehensive patient overview.
IntroductionClinical evidence highlighting the efficacy and safety of transcatheter aortic valve replacement (TAVR) and the 2019 Food and Drug Administration (FDA) approval for TAVR in low-risk (younger) patients has created a demand for durable and long-lasting bioprosthetic heart valve (BHV) leaflet materials. Over the life of an implanted BHV mechanical stress, immunogenicity, calcification, and hemodynamic dysfunction lead to failure via structural valve deterioration (SVD).
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
It may not have caught any healthcare industry leaders by surprise when heart disease and stroke continued to top the list of leading causes of death in the U.S. in 2022. The average $417.9 billion annual price tag for the diseases may not have caused some hospital officials to bat an eye, either. But one Cleveland Clinic expert is imploring executives not to look away.
IntroductionUnderstanding the influence of body position on cardiovascular responses during exercise is crucial for precise diagnostic and therapeutic strategies, particularly in patients with exercise intolerance.AimThis study aims to compare the hemodynamic responses to exercise in upright and recumbent cycling positions in patients with exercise intolerance.MethodsA cross-over study design was employed, enrolling 21 patients for right heart catheterization during exercise in both upright and
Patients with end-stage renal disease face a significantly higher risk of cardiovascular diseases. For patients who are candidates for renal transplantation (RT), major surgeries such as coronary artery bypass grafting (CABG) are associated with cardiac complications as well as higher rates of post-operative complications, including the need for large amounts of blood transfusion, worsening kidney function, infection, and graft rejection.
ObjectivePlatelet-to-white blood cell ratio (PWR) as a comprehensive indicator of inflammatory response has been widely used to assess the prognosis of various diseases. However, the relationship between PWR and adverse outcomes in patients with acute decompensated heart failure (ADHF) remains unclear. This study aimed to evaluate the association between PWR and all-cause mortality within 30 days of hospitalization in ADHF patients from Jiangxi, China.MethodsA total of 1,453 ADHF patients from t
The rising prevalence of obesity and its association with heart failure with preserved ejection fraction (HFpEF) highlight an urgent need for a diagnostic approach tailored to this population. Diagnosing HFpEF.
(MedPage Today) -- Some patients with diabetes may be missing critical safety alerts on their phones, the FDA warned on Wednesday. The agency said it has received reports of users of smartphone-compatible diabetes devices -- such as insulin.
Research Highlights: Neither a placebo procedure nor two different doses of transcranial brain stimulation, which send electrical signals through the skull, improved mobility recovery in stroke survivors receiving movement therapy. Motor function was.
(MedPage Today) -- LOS ANGELES -- A strategy of minimally invasive surgery (MIS) for spontaneous intracerebral hemorrhage (ICH) failed to meet expectations in the MIND trial. Patients who underwent MIS with the Artemis NeuroEvacuation device.
This report describes the transplantation of a gene-edited porcine kidney in a hemodialysis-dependent man with long-standing diabetes, advanced vasculopathy, and marked dialysis-access challenges.
Limited evidence supports apixaban's use for atrial fibrillation (Af) in severe chronic kidney disease (CKD) or end-stage kidney disease (ESKD) patients, where warfarin is often contraindicated.
The research found that heavy drinkers with either diabetes, high blood pressure or a high waist circumference are as much as 2.4 times more likely to develop advanced liver disease.
Among patients with takotsubo syndrome (TTS), beta-blocker therapy was associated with lower follow-up mortality but not lower TTS recurrence, according to a study published Feb. 5 in JACC: Heart Failure.
Atrial fibrillation (AF) is a relatively prevalent arrhythmia in patients with kidney failure requiring dialysis, who face a high risk of stroke and bleeding, and anticoagulation is a challenging decision. Although direct oral anticoagulants (DOACs) may offer advantages over warfarin K antagonists (VKAs), their use in this patient profile remains unclear.
A team of physicists has developed a groundbreaking method for detecting congestive heart failure with greater ease and precision than previously thought possible. This multidisciplinary study, involving both cardiologists and computational physicists, builds on the team's earlier breakthroughs, for example, in predicting the risk of sudden cardiac death.
The risk of incident heart failure (HF) after a myocardial infarction (MI) is up to six-fold higher than the risk of recurrent MI and the prognosis is worse among those who develop incident HF, regardless of LVEF category.
New ACP migraine guidelines recommend -blockers, valproate, venlafaxine, or amitriptyline for episodic migraine prevention before using CGRP-targeting drugs.
Researchers continue to advance the science to determine best treatments for stroke. Based on an international study of 530 patients, researchers discovered that while the clot retrieval procedure endovascular thrombectomy (EVT) can dramatically improve patient outcomes after an acute ischemic stroke caused by a blockage in a large blood vessel, it did not improve outcomes in patients with blockages in medium-sized vessels.
A lower treatment threshold of 130/80 mm Hg was associated with reduced postpartum emergency department (ED) visits for a hypertensive disorder of pregnancy (HDOP), according to a study.
This segment of Heberts interview features a discussion regarding the safety profile of tapinarof 1% for patients aged 2 years and older with atopic dermatitis.
Patients with a history of cardiovascular disease, compared with those without, had a higher incidence of sudden cardiac death (SCD), according to a study of 5.5 million Danish citizens in 2010.
History of prior heart failure (HF) was found to influence prognostic implications of atrial fibrillation (AFib) in patients hospitalized for HF, with permutations of prior HF, prior AFib and AFib as presenting rhythm differentiating outcome.
Nature Reviews Cardiology, Published online: 07 February 2025; doi:10.1038/s41569-025-01133-2 A new study shows that activation of vagal sensory neurons expressing the oxytocin receptor in the cardiovascular and gastrointestinal tissues of mice mediates cardiometabolic changes resembling those from a hibernation-like, hypometabolic state.
The association between the stress hyperglycemia ratio (SHR), which represents the degree of acute stress hyperglycemic status, and the risk of mortality in cerebrovascular disease patients in the intensive ca.
Nature Reviews Cardiology, Published online: 07 February 2025; doi:10.1038/s41569-025-01134-1 Elizabeth Figueroa-Jurez describes the study that demonstrated that fibroblasts derived from endothelial cells through endothelial-to-mesenchymal transition contribute to cardiac fibrosis.
Epicardial and pericardial adipose tissues are two distinct types of visceral fat in close adherence to the heart and were found to be increased among diabetics.
SGLT2 inhibitors lower the risk of MACE in older age, despite smaller HbA1c reductions, while GLP-1 RAs were more cardioprotective in younger individuals with T2D.
Cardiovascular autonomic neuropathy (CAN), characterized by disrupted autonomic regulation of the cardiovascular system, is a frequent complication associated with diabetes. The triglyceride-glucose (TyG) inde.
Stanza previously demonstrated efficacy in helping to manage fibromyalgia in adult patients when compared with digital symptom tracking in phase 3 data.
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