Tue.May 21, 2024

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Night-time heat significantly increases the risk of stroke

Science Daily - Stroke

Researchers show that nocturnal heat significantly increases the risk of stroke. The findings can contribute to the development of preventive measures: With them, the population can better protect themselves against the risks of climate change with increasingly frequent hot nights. In addition, knowledge of the consequences of hot nights can improve patient care.

Stroke 112
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New PAD Guidelines; AHA on Postpartum Care; Exercise Didn't Stop CAC Progression

Med Page Today

(MedPage Today) -- Low-dose rivaroxaban (Xarelto), SGLT2 inhibitors, and GLP-1 receptor agonists have entered multisocietal guidelines on peripheral artery disease (PAD) for the first time. (Circulation) Recommendations for postpartum care were.

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Cardiac Care AI Company, Anumana, Announces Receipt of ISO 13485 Certification

DAIC

Cambridge, MA-based artificial intelligence (AI)-driven health technology company, Anumana, has announced its receipt of the International Organization for Standardization (ISO) 13485 certification for its Quality Management System. ECG-AI LEF, the company’s breakthrough AI algorithm, received U.S. Food and Drug Administration (FDA) clearance in September 2023.

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Analysis: Pulsed Field Afib Ablation Superior to Thermal Methods

Med Page Today

(MedPage Today) -- BOSTON -- Pulsed field ablation (PFA) trials continued to accrue positive data, as reported at the Heart Rhythm Society (HRS) annual meeting. Superiority, Finally Secondary analysis of the pivotal ADVENT trial showed that.

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Primary Care Roles in Alzheimer Diagnosis, with Theresa Sivers-Teixeira, MSPA, PA-C

HCPLive

Sivers-Teixeira explains that while the care team should quickly expand once dementia has presented in screening, the primary care role stays consistent.

Dementia 105
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Current State of MRI With Cardiac Devices

American College of Cardiology

Magnetic resonance imaging (MRI) is increasingly performed each year due to expanding indications, both cardiac and noncardiac, and to enhanced access. The same drivers have increased the use of cardiac implantable electronic devices (CIEDs).

Article 75
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Bidirectional Link Identified Between Depression, Inflammatory Joint Disease

HCPLive

This analysis may require further research to determine whether other treatment-resistant depression or severe depression definitions are specifically associated with inflammatory joint disease.

More Trending

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Increasing Evidence Supporting Preventive Benefits of Exercise in Women

NEJM Journal Watch - Cardiology

In observational studies, more physical activity was associated with less HFpEF among women and showed a stronger association with reduced mortality than in men.

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Naim Alkhouri, MD: Interim Analysis of Phase 2 Survodutide Data Show Promise for MASH, Fibrosis

HCPLive

Alkhouri explains survodutide’s mechanism of action as a glucagon/GLP-1 receptor dual agonist and reviews key findings about its use in MASH from the interim analysis.

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Cardiology employment, pay and well-being in 35 numbers

Becker's Hospital Review - Cardiology

Several reports have gone live in the first half of 2024 that give an insight into cardiologist employment, pay, burnout and coping mechanisms.

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Patient Involvement in Advanced HF Treatment, with Ashley Malliett, DMSc, MPAS, PA-C

HCPLive

Malliett discusses the signs that a caregiver should refer to an HF specialist for advanced care options, including LVAD and heart transplant.

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A systematic review and meta-analysis of randomized controlled trials comparing low-dose versus standard-dose computed tomography-guided lung biopsy

Journal of Cardiothoracic Surgery

Despite the existence of several Randomized Controlled Trials (RCTs) investigating Low-Dose Computed Tomography (LDCT) as a guide in lung biopsies, conclusive findings remain elusive. To address this contentio.

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High-Dose Etanercept Can Improve JIA, Increase Risk of Non-Severe Events

HCPLive

New analysis suggests use of high-dose etanercept may help children with juvenile idiopathic arthritis achieve remission and reduce disease activity.

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Study in JAHA Links Hello Heart Usage to Significant Reductions in Blood Pressure, Cholesterol, and Weight

DAIC

A new peer-reviewed study published in the Journal of the American Heart Association , JAHA, found that Hello Heart’s digital heart health program was associated with reductions in blood pressure (BP), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and weight. Image courtesy: Hello Heart christine.book Tue, 05/21/2024 - 23:22 May 23, 2024 — A newly-published peer-reviewed study in the Journal of the American Heart Association , JAHA , found that Hello Heart’s digital heart

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REGENERATE: Final Results for Obeticholic Acid for Pre-Cirrhotic Fibrosis Due to NASH

HCPLive

End-of-study results from the phase 3 REGENERATE study were presented at DDW and highlight obeticholic acid’s trend in benefit for clinical outcomes.

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Case Report: A rare transthyretin mutation p.D58Y in a Chinese case of transthyretin amyloid cardiomyopathy

Frontiers in Cardiovascular Medicine

Hereditary transthyretin amyloid (ATTRv) cardiomyopathy (CM) is caused by mutations in the TTR gene. TTR mutations contribute to TTR tetramer destabilization and dissociation, leading to excessive deposition of insoluble amyloid fibrils in the myocardium and finally resulting in cardiac dysfunction. In this article, we report a case of a Chinese patient with transthyretin mutation p.D58Y and provide detailed information on cardiac amyloidosis, including transthoracic echocardiography, cardiac ma

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Paul Feuerstadt, MD: Safety, Efficacy of Live-jslm in Patients Taking Concomitant Medications

HCPLive

Feuerstadt breaks down findings from an ad hoc analysis of PUNCH CD3 and what the results suggest about the use of live-jslm (Rebyota) in patients taking concomitant medications.

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Endovascular intervention with intravascular ultrasound guidance of very early dissection complication in transplant renal artery: a case report and literature review

Frontiers in Cardiovascular Medicine

BackgroundTransplant renal artery dissection (TRAD) is a rare and serious event that can cause allograft dysfunction and eventually graft loss. Most cases are managed by operative repair. We report a case of TRAD in the early postoperative period, which was successfully managed with intravascular ultrasound-assisted endovascular intervention.Case presentationA 38-year-old man underwent HLA-compatible living kidney transplantation.

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Addressing Non-Adherence in Resistant Hypertension, with Swapnil Hiremath, MD, MPH

HCPLive

Swapnil Hiremath, MD, MPH, discusses resistant hypertension, including using an evidence-based approach to management and addressing non-adherence.

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Outcomes of Patients Presenting with Non-ST Elevation Myocardial Infarction Undergoing Surgical Revascularization.

The American Journal of Cardiology

Publication date: Available online 20 May 2024 Source: The American Journal of Cardiology Author(s): Marsioleda Kemberi, Eduardo Urgesi, Ji ngYong Ng, Kush Patel, Mohammed Y Khanji, Wael I Awad

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ESA Hyporesponders More Likely to Receive Higher Doses of Daprodustat, ESA

HCPLive

At the end of the study period, the median dose of daprodustat and ESA were higher among the ESA-HR cohort when compared with the non-ESA-HR group.

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The longitudinal incidence of pericarditis in 1.6 million patients: a 20-year study

The American Journal of Cardiology

Publication date: Available online 20 May 2024 Source: The American Journal of Cardiology Author(s): Shaye Kivity, Tomer Ziv Baran, Miri Mizrahi Reuveni, Angela Irony, Limor Adler, Yehuda Alder, Roma Parikh, Sara Kivity

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Inflammation and coronary microvascular disease: relationship, mechanism and treatment

Frontiers in Cardiovascular Medicine

Coronary microvascular disease (CMVD) is common in patients with cardiovascular risk factors and is linked to an elevated risk of adverse cardiovascular events. Although modern medicine has made significant strides in researching CMVD, we still lack a comprehensive understanding of its pathophysiological mechanisms due to its complex and somewhat cryptic etiology.

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STARS: Apraglutide Reduces Parenteral Support in Patients with Stoma, Colon-In-Continuity

HCPLive

New STARS data were presented in a late-breaking abstract at DDW and build upon positive topline results for clinical responder rates and reductions in parenteral support.

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Fourth Intensive Ambulance-Delivered Blood Pressure Reduction in Hyper-Acute Stroke Trial

American College of Cardiology

The goal of the INTERACT4 trial was to determine the effect of prehospital treatment of elevated systolic blood pressure (SBP) in patients with recent onset of symptoms concerning for acute stroke.

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Clinical Quiz: AGA Recommendations on Endoscopic Eradication Therapy of Barrett’s Esophagus

HCPLive

A detailed overview and accompanying quiz on the recommendations made by the AGA in their 2024 guideline on endoscopic eradication

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Ultimate DAPT Trial Principal Results – Ticagrelor monotherapy post PCI for reducing clinically meaningful bleeding

American College of Cardiology

In this interview, Gregg W Stone MD, FACC and Anthony N. DeMaria MD, MACC discuss principal results from the Ultimate DAPT Trial.

Article 63
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Novel Endoscopy System Feasible for Evaluation of Upper GI Diseases

HCPLive

A cable-transmission magnetically controlled capsule endoscopy showed comparability to conventional methods in upper GI tract examinations and lesion detection.

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Rheumatoid Arthritis and CV Complications During Delivery

American College of Cardiology

What is the association of rheumatoid arthritis (RA) with acute cardiovascular (CV) complications during delivery?

Article 60
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Restoring dislocated shoulders an innovative minimal way

HCPLive

Arthroscopic approach with augmentation of the labrum repair has resulted in complete restoration of shoulder function and a permanent stop to dislocations.

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Transcatheter or Surgical Replacement for Failed Bioprosthetic Aortic Valves

JAMA Cardiology

This cohort study evaluates mortality and morbidity outcomes among patients undergoing transcatheter or surgical replacement for failed bioprosthetic aortic valves.

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Heart Failure Treatment Outcomes and Contraindications

HCPLive

Ashley Malliett, DMSc, MPAS, PA-C, discusses the importance of timely diagnosis and initiated care, as well as contraindications for transplants and LVAD.

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Circumferent dissection of the ascending aorta resulting in the occlusion of supra-aortic vessels repaired using the frozen elephant trunk technique - a case report

Journal of Cardiothoracic Surgery

Our patient presented with acute back pain and dyspnea, without neurological symptoms. The computed tomography (CT) scan showed a circumferent rupture of the ascending aortic intima which was invaginated in th.

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Blood-Based Test Offers Effective Screening Option for Colorectal Cancer

HCPLive

Data from PREEMPT CRC reveal the blood-based screening test demonstrated a 79.2% sensitivity for detecting colorectal cancer.

Cancer 59
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Clinical analysis of temporary pacemaker implantation in 6 children with fulminant myocarditis

Journal of Cardiothoracic Surgery

There is little literature on the use of temporary pacemakers in children with fulminant myocarditis. Therefore, we summarized the use of temporary cardiac pacemakers in children with fulminant myocarditis in.

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GALAXI 2 & 3: Guselkumab Superior to Ustekinumab for Crohn's Disease

HCPLive

Both doses of guselkumab exhibited statistical superiority on all prespecified pooled endoscopic endpoints versus ustekinumab in Crohn's disease.

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Optimal antiPlatelet Therapy for high Bleeding and Ischemic RISK patients

American College of Cardiology

The goal of the OPT-BIRISK trial was to compare the safety and efficacy of clopidogrel monotherapy compared with dual antiplatelet therapy (DAPT) with aspirin and clopidogrel as maintenance therapy after completion of 9-12 months of DAPT following drug-eluting stent (DES) percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS).

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