Wed.Jul 24, 2024

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Persistent Anxiety Tied to Future Dementia

Med Page Today

(MedPage Today) -- Persistent anxiety raised the risk of all-cause dementia in older adults, a longitudinal study showed. Both chronic anxiety (HR 2.80, 95% CI 1.35-5.72, P=0.01) and new-onset anxiety (HR 3.20, 95% CI 1.40-7.45, P=0.01) were tied.

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Physical activity improves early with customized text messages in patients with heart problems

Science Daily - Heart Disease

Personalized text messages effectively promoted increased physical activity for patients after significant heart events -- such as a heart attack or surgery -- but those effects later diminished. Researcher say the results show incredible promise for simple, low cost interventions delivered through mobile technology and their potential to help prevent secondary cardiovascular events in patients.

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Stroke recovery: It's in the genes

Science Daily - Stroke

New research has found that specific genes may be related to the trajectory of recovery for stroke survivors, providing doctors insights useful for developing targeted therapies.

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Increasing cardiac ketones may help heart failure in mouse study

American Heart News - Heart News

Research Highlights: In mice with heart failure with preserved ejection fraction (HFpEF), increasing ketone supply to the heart allowed their hearts to utilize more ketones and produce more energy. Researchers hope this study may help to improve our.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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The Case for Keto for Type 1 Diabetes with Andrew Koutnik, Ph.D.

Physiologically Speaking

Greetings! Today’s interview is with Andrew Koutnik, Ph.D. Andrew is a research scientist at Sansum Diabetes Research Institute, where he’s investigating metabolic therapies for health and disease. His mission is to optimize metabolic health and patient outcomes for people living with type 1 diabetes. Andrew is unique because he himself has type 1 diabetes.

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Increasing Prediabetes remission for type 2 diabetes

Science Daily - Heart Disease

In mice with heart failure with preserved ejection fraction (HFpEF), increasing ketone supply to the heart allowed their hearts to utilize more ketones and produce more energy.

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FibriCheck Enters US Market with FDA Clearance

DAIC

mtaschetta-millane Wed, 07/24/2024 - 11:34 July 24, 2024 — After a rigorous investigation procedure by the Food and Drug Administration, FibriCheck is now FDA-cleared (K232804). This is an important milestone which supports FibriCheck’s further development in the U.S. market. The FDA-clearance also allows FibriCheck to improve current U.S. care pathways and to provide millions of Americans with the ability to just use their smartphone to obtain easy and accurate heart rhythm measurements.

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Serum Complement Levels Demonstrate Prognostic Value in IgA Nephropathy

HCPLive

Integrating serum C3 and C4 levels into existing prognostic scores led to better prediction accuracy and may help optimize risk stratification in patients with IgAN.

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Volta Medical Enters into Joint Development Agreement with GE HealthCare to Support Electrophysiologists Treating Atrial Fibrillation

DAIC

Volta Medical has announced it has entered into a Joint Development Agreement with GE Healthcare to enhance arrhythmia procedures with artificial intelligence (AI)-driven electrophysiology technologies. The collaboration, according to a written statement issued by the company, aims to address challenges in capturing and analyzing cardiac signals to help physicians enhance patient outcomes for atrial fibrillation procedures.

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Hemophilia A Gene Therapy Displays Superiority in Phase 3 AFFINE Trial

HCPLive

Giroctocogene fitelparvovec achieved primary and key secondary objectives of superiority compared to routine prophylaxis in hemophilia A treatment.

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Chronic Thromboembolic Pulmonary Hypertension: the therapeutic assessment

Frontiers in Cardiovascular Medicine

Chronic Thromboembolic Pulmonary Hypertension (CTEPH) is a severe and complex condition that evolves from unresolved pulmonary embolism, leading to fibrotic obstruction of pulmonary arteries, pulmonary hypertension, and potential right heart failure. The cornerstone of CTEPH management lies in a multifaceted therapeutic approach tailored to individual patient profiles, reflecting the disease's heterogeneity.

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Improving Schizophrenia Management: A Patient's Call to Care Providers

HCPLive

Schizophrenia experts discuss the stigma and misconceptions surrounding schizophrenia as well as current treatment options.

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Study shows everyday activities aren't enough to protect against stroke

Medical Xpress - Cardiology

Research conducted at the University of Gothenburg shows that the physical activities we do as we go about our lives, at work or in the home, aren't enough to protect us from having a stroke. However, exercising in our free time and using active modes of transport are associated with a decreased risk of stroke. The study is published in JAMA Network Open.

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Early Intervention, Lifelong Prevention: Targeting Subclinical ASCVD in Young Adults

American College of Cardiology

Cardiovascular disease (CVD) remains the leading cause of death and disability worldwide. Early intervention and strict control of modifiable CV risk factors in adolescents and young adults will likely reduce the significant morbidity, mortality, and socioeconomic burden associated with the condition.

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Mouse study finds increasing cardiac ketones may help treat heart failure

Medical Xpress - Cardiology

Increasing ketone supply to the heart in mice with heart failure with preserved ejection fraction (HFpEF) allowed their hearts to utilize more ketones and produce more energy, according to preliminary research presented today at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions 2024. The meeting is in Chicago, July 22–25, 2024, and offers the latest research on innovations and discovery in cardiovascular science.

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Study Links Air Pollution Exposure During Pregnancy to Reduced Lung Function in Childhood

HCPLive

These data highlighted the association of moderate air pollution exposure during pregnancy, infancy, and early childhood on pulmonary function at school age.

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Wearable devices may increase health anxiety, atrial fibrillation study finds

Medical Xpress - Cardiology

Using a wearable device, such as a smart watch, to track health data and symptoms, is supposed to help people monitor their health and address symptoms as quickly as possible to spur positive health outcomes. But for people with atrial fibrillation, also known as Afib, using a wearable device to monitor the heart rate and to alert wearers of an irregular heartbeat might not be as helpful as wearers think.

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Pooled Cohort Equation Bests Life's Essential 8, Simple 7 for Predicting Long-Term CVD Risk

HCPLive

UAB research shows AHA’s Life’s Essential 8 and Simple 7 scores aid public health but are less effective than pooled cohort equations for predicting individual cardiovascular risk.

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New study identifies a key role for pharmacists in stroke risk reduction

Medical Xpress - Cardiology

According to Dr. Roopinder Sandhu, MD, MPH, atrial fibrillation (Afib) is the most common heart rhythm disorder encountered in clinical practice, and the leading cause of stroke in older individuals. Sandhu, a cardiac electrophysiologist and the Director of the Women's Cardiovascular Health Initiative at the Cumming School of Medicine, University of Calgary, says despite the availability of blood thinners that are highly effective and safe to reduce the risk of stroke, major gaps in the delivery

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Elevating Your Medical Expertise, The Essential Training for Doctors to Excel

ADN Center of Excellence

As a dedicated medical professional, you're well aware that the journey to excellence in healthcare is a continuous one. The rapid pace of medical advancements and evolving patient expectations demand that doctors constantly refine their skills and expand their knowledge. At ADN Center of Excellence , we understand the challenges you face and are committed to providing the training you need to excel in your field.

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Magenta Medical Adds $105M, Targets MCS Disruption

CardiacWire

Israeli heart pump startup Magenta Medical wrapped up a $105M financing round to advance clinical programs supporting its Elevate left ventricular assist device, a percutaneous heart pump that Magenta believes could disrupt the mechanical circulatory support (MCS) segment. The miniature Elevate device is folded and delivered percutaneously through the femoral artery (8 Fr inner diameter, 10 Fr sheath), passing through the aorta and aortic valve, before self-expanding in patients’ hearts where it

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Tampa General researchers develop new heart transplant device

Becker's Hospital Review - Cardiology

Discover the innovative device developed by Tampa General Hospital researchers that extends the viability of transplant hearts by three hours

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Semaglutide May Reduce Rates of Diabetic Retinopathy Outcomes

HCPLive

A database analysis linked semaglutide use to notable reductions in the rates of diabetic macular edema and vitreous hemorrhage in diabetic retinopathy.

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Lp(a) and Coronary Plaque Progression

American College of Cardiology

What is the association of lipoprotein(a) (Lp[a]) levels with long-term coronary artery plaque progression, development of high-risk plaque, and pericoronary adipose tissue inflammation?

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Positive Outcomes Observed Among Those With COPD in Nurse, Allied Health–Led Clinic

HCPLive

This model and its service components may be implemented in the future to allow for improvements to primary care programs, with the goal being benefits to patients with COPD.

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Diuretics and HF, ICDs and the Tricuspid Valve and Right Ventricle, Neurohormonal Blockade and HF

American College of Cardiology

In this week’s View, Dr. Eagle looks at a study comparing three diuretic regimens in ambulatory congested heart failure (HF) patients (DEA-HF).

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Adverse event risk up for >90 days versus >30 days of corticosteroids for eczema

Medical Xpress - Cardiology

Use of oral corticosteroids for >90 days during one year is associated with a slightly increased risk of adverse events (AEs), according to a study published online July 19 in JAMA Network Open.

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Medications for Obesity: Key Points

American College of Cardiology

The following are key points to remember from a review of medications used to treat obesity.

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Physical activity found to improve early with customized text messages in patients with heart problems

Medical Xpress - Cardiology

Exercise is one of the best ways to reduce your risk of heart disease or having a second cardiovascular event, such as a heart attack or stroke.

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Temperature and Neurologic Outcomes in Neonatal Cardiac Surgery

American College of Cardiology

What is the association between nadir intraoperative temperature (NIT) and early neurologic outcomes in neonates undergoing congenital heart surgery?

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Elevating Your Medical Expertise, The Essential Training for Doctors to Excel

ADN Center of Excellence

As a dedicated medical professional, you're well aware that the journey to excellence in healthcare is a continuous one. The rapid pace of medical advancements and evolving patient expectations demand that doctors constantly refine their skills and expand their knowledge. At ADN Center of Excellence , we understand the challenges you face and are committed to providing the training you need to excel in your field.

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KM04416 suppressed lung adenocarcinoma progression by promoting immune infiltration

Journal of Cardiothoracic Surgery

Lung adenocarcinoma (LUAD) is a malignant tumor originating from the bronchial mucosa or glands of the lung, with the fastest increasing morbidity and mortality. Therefore, the prognosis of lung cancer remains.

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Screening for carotid atherosclerosis: development and validation of a high-precision risk scoring tool

Frontiers in Cardiovascular Medicine

ObjectiveThis study aimed to investigate the prevalence of carotid atherosclerosis (CAS), especially among seniors, and develop a precise risk assessment tool to facilitate screening and early intervention for high-risk individuals.MethodsA comprehensive approach was employed, integrating traditional epidemiological methods with advanced machine learning techniques, including support vector machines, XGBoost, decision trees, random forests, and logistic regression.ResultsAmong 1,515 participants

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The impact of bleeding on outcomes following lung transplantation: a retrospective analysis using the universal definition of perioperative bleeding

Journal of Cardiothoracic Surgery

Lung transplantation (LT) represents a high-risk procedure for end-stage lung diseases. This study describes the outcomes of patients undergoing LT that require massive transfusions as defined by the universal.

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Case Report: Patent ductus arteriosus with tuberous sclerosis complex

Frontiers in Cardiovascular Medicine

A 33-year-old patient presented with a chief complaint of patent ductus arteriosus (PDA) persisting for over 30 years. Physical examination revealed bilateral facial angiofibromas, multiple nail fibromas, intraoral fibromas, and a ’shagreen patch’ on the left lumbar region. Genetic testing was performed using a peripheral venous blood sample, which confirmed the diagnosis of Tuberous Sclerosis Type 2 (TSC2).

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Healthy Prenatal Dietary Pattern Linked to Lower Odds of Child Having Autism

HCPLive

A new study found a high adherence to a healthy prenatal dietary pattern was associated with a 22% reduced likelihood of an offspring autism diagnosis.

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