Thu.Jul 04, 2024

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ECG Blog #437 — A 2-Part Answer.

Ken Grauer, MD

I was sent the ECG in Figure-1 — but without the benefit of any history. QUESTIONS: How would YOU interpret this tracing? WHY do I say there is, "A 2-Part Answer?" Figure-1: The initial ECG in today's case. ( To improve visualization — I've digitized the original ECG using PMcardio ). MY Thoughts on Today's CASE: As important as providing a brief, relevant history is for optimal clinical ECG interpretation — Cases like the one today often prove even more educational, because we are not given any

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The LDL cumulative exposure hypothesis: evidence and practical applications

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 05 July 2024; doi:10.1038/s41569-024-01039-5 In this Review, Catapano and colleagues discuss the evidence supporting the LDL cumulative exposure hypothesis and how measuring cumulative LDL exposure can be used to estimate risk and contribute to the prevention of atherosclerotic cardiovascular disease.

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Adiposity, fat-free mass and incident heart failure in 500 000 individuals

Open Heart

Background and aims The independent role of body fat distribution and fat-free mass in heart failure (HF) risk is unclear. We investigated the role of different body composition compartments in risk of HF. Methods Present analyses include 428 087 participants (mean age 55.9 years, 44% male) from the UK Biobank. Associations of long-term average levels of body composition measures with incident HF were determined using adjusted Cox proportional hazards regression models.

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Dermatology in 2024: FDA First Half Recap, with James Del Rosso, DO

HCPLive

Our dermatology FDA recap for the first half of 2024 includes our top 5 approvals, 3 decisions to watch in the second half of 2024, and a podcast episode with James Del Rosso, DO

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Association between atherogenic index of plasma and gestational diabetes mellitus: a prospective cohort study based on the Korean population

Cardiovascular Diabetology

Atherogenic index of plasma (AIP) is a non-traditional lipid parameter that can reflect the burden of atherosclerosis. A lipid profile resembling atherosclerosis emerged during pregnancy. Although lipid metabo.

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Gastroenterology Month in Review: June 2024

HCPLive

The June 2024 gastroenterology month in review highlights FDA news and other pipeline developments in GI as well as the publication of the latest installment of Qazi Corner.

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Excessive accumulation of epicardial adipose tissue promotes microvascular obstruction formation after myocardial ischemia/reperfusion through modulating macrophages polarization

Cardiovascular Diabetology

Owing to its unique location and multifaceted metabolic functions, epicardial adipose tissue (EAT) is gradually emerging as a new metabolic target for coronary artery disease risk stratification. Microvascular.

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Happy 4th from the DAIC team

DAIC

The DAIC team wishes you a safe and happy 4th of July!

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Higher Transferrin Saturation Levels Linked to Fewer CV Events in CKD

HCPLive

Patients with chronic kidney disease and TSAT levels of 30–40% experienced significantly fewer cardiovascular events than those with TSAT of 20–30%.

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Therapeutic effect of induction therapy including nab-paclitaxel followed by surgical resection for the patients with locally advanced non-small-cell lung cancer

Journal of Cardiothoracic Surgery

Lung cancer is associated with a high mortality rate worldwide. Non-small-cell lung cancer (NSCLC) is a major subtype of lung cancer. Carboplatin (CBDCA) plus nab-paclitaxel (PTX) has become a standard treatme.

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How Elite Athletes Can Optimize Sleep for Peak Performance, with Jesse D. Cook, PhD

HCPLive

Cook explains to HCPLive how elite athletes can optimize sleep for peak performance.

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Which one is the best in treating deep venous thrombosis —— percutaneous mechanical thrombectomy, catheter-directed thrombolysis or combination of them?

Journal of Cardiothoracic Surgery

To compare the treatment outcomes among percutaneous mechanical thrombectomy (PMT) with AngioJet, Catheter-directed thrombolysis (CDT), and a combination of both.