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Research Highlights: Two new, basic research studies in rodents (mice and rats) analyzed the impacts that alcohol may have on the heart. In a mouse study, abnormal heart rhythms that can occur after a pattern of repeated simulation of binge drinking.
(MedPage Today) -- It might take giving people money directly for them to participate in cardiac rehabilitation, a randomized trial showed. Eligible patients in Vermont of lower socioeconomic status had cardiac rehab adherence rates shoot up if.
A new study has identified new genetic and molecular risk factors that may reveal new pathways for treating patients after they experience their first stroke. The study identified CCL27 and TNFRSF14, two proteins that are associated with subsequent MACE, but not initial strokes. These proteins are known to activate inflammation, which plays a key role in the development of strokes and many chronic conditions and diseases.
(MedPage Today) -- The proportion of new users of GLP-1 receptor agonists without type 2 diabetes markedly increased over the past decade, and particularly since 2020, according to a nationwide population-based study of prescribing trends. Overall.
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Nieca Goldberg, MD, board-certified cardiologist, educator, author, and advocate for women’s health, has announced she is returning to practice at NYU Langone Health, where she also serves as Clinical Associate Professor, Department of Medicine at NYU Grossman School of Medicine. Image courtesy: Finn Partners christine.book Mon, 07/22/2024 - 11:36 July 22, 2024 — Nieca Goldberg, MD , a board-certified cardiologist, educator, author, and advocate for women’s health, has announced that she is retu
The analysis of NHANES data found individuals with viral hepatitis and NAFLD as well as lower income and no college education were at a greater risk of mortality.
Heart failure with preserved ejection fraction (HFpEF) is a mortal clinical syndrome without effective therapies. Empagliflozin (EMPA) improves cardiovascular outcomes in HFpEF patients, but the underlying mec.
Heart failure with preserved ejection fraction (HFpEF) is a mortal clinical syndrome without effective therapies. Empagliflozin (EMPA) improves cardiovascular outcomes in HFpEF patients, but the underlying mec.
Research Highlights: Adults in their 50s with peripheral artery disease or PAD — are more likely than adults older than 80 to undergo leg amputation one to five years after an emergency surgery to restore blood flow to the lower limbs. This study.
What is the relationship between intensive uptitration of guideline-directed medical therapy (GDMT) for heart failure (HF) during the early post-discharge period, and what are the outcomes?
An analysis using records from 40 million US patients highlights the surge in new GLP-1 receptor agonist use, with semaglutide dominating new prescriptions since 2020.
Among patients who underwent a PCI, the increased risk of death was similar at one year among those who had a procedural myocardial infarction (pMI) and those who had a spontaneous myocardial infarction (spMI) when their troponin level was >35x the upper reference level (URL).
"George Washington University appoints Steven Boyce, MD as chief of Division of Cardiac Surgery and professor of surgery at GW School of Medicine and Health
These findings represent the first comprehensive research into the greater frequency of APS autoantibodies linked with treating psoriasis with TNF inhibitors.
A significant percentage of patients with acute coronary syndrome (ACS) without standard modifiable cardiovascular risk factors (SMuRFs) are being identified. Nonetheless, the prognostic influence of the TyG i.
BackgroundPercutaneous left atrial appendage closure (LAAC) serves as an alternative prophylactic strategy for patients with non-valvular atrial fibrillation (AF) who cannot undergo anti-coagulation therapy. Proper management of associated complications is crucial to enhancing the procedure's success rate and mitigating perioperative risks and adverse events during follow-up.AimsThis study aims to summarize our center's experience and strategies in managing procedural-related complications encou
IntroductionIn developing countries, there is a notable scarcity of real-world data on adherence to optimal medical therapy (OMT) and its correlation with major cardiovascular adverse events (MACEs) after ST-elevation myocardial infarction (STEMI). Our study focuses on addressing this gap by evaluating adherence to OMT, examining its influence on the risk of MACEs after STEMI, and assessing subsequent cardiovascular risk factor control in Mexico.MethodsWe conducted a prospective observational st
ObjectiveTo characterize the gas production phenomenon in the animal model of left ventricular assist device (LVAD), and study its mechanism.MethodsAn in vitro bubble precipitation experiment was conducted, and the blood samples of Parma spp. animals were divided into ordinary group and oxygen-enriched group according to whether they were oxygenated or not at the time of blood collection, and a static control group was set up respectively.
Johnson & Johnson submits a supplemental New Drug Application to the FDA for the approval of esketamine as a monotherapy for adults with treatment-resistant depression.
Placental function plays a crucial role in fetal development, as it serves as the primary interface for delivery of nutrients and oxygen from the mother to fetus. Magnetic resonance imaging (MRI) has significantly improved our ability to visualize and understand the placenta's complex structure and function. This review provides an up-to-date examination of the most common and novel placental MRI techniques.
A new blood-based lipodomic-enhanced risk score (LRS) augmenting the Framingham Risk Score (FRS) may be superior to the FRS alone in improving stratification of intermediate-risk patients for primary prevention.
These data suggest that the introduction of the concept of circadian syndrome contributes to greater understanding of risk management for those with psoriasis.
The researchers report the ability of protein 'signatures' to predict the onset of 67 diseases including multiple myeloma, non-Hodgkin lymphoma, motor neurone disease, pulmonary fibrosis, and dilated cardiomyopathy.
Cardiac dysfunction, including arrhythmias, may be one of the main clinical manifestations of Becker muscular dystrophy (BMD). Amiodarone is widely used to treat arrhythmia. However, multi-systemic toxicity ca.
Data from INSPIRE and COMMAND were used to support risankizumab’s FDA approval for ulcerative colitis, demonstrating the IL-23 inhibitor’s impact on clinical remission.
A study published in The Lancet reveals that targeting a systolic blood pressure of less than 120 mm Hg significantly reduces cardiovascular events in high-risk patients, compared to the standard target of less than 140 mm Hg. This multicenter open-label, blinded-outcome, randomized trial ( NCT04030234 ), offers new insights into hypertension management.
Christopher Bunick, MD, PhD, examines patient satisfaction upon achieving primary study endpoints in clinical trials and highlights the significance of patient-reported outcomes (PROs) in both clinical trial designs and patient care.
The following are key points to remember from a state-of-the-art article describing how artificial intelligence (AI) applications can improve patient evaluation by combining clinical expertise with technologic advancements.
An atopic dermatitis expert describes the results of the Level Up study, a phase 3b/4 trial comparing upadacitinib and dupilumab, which were recently presented at RAD 2024, focusing on the primary and secondary outcomes of the study.
The goal of the ADVENT trial was to compare the safety and efficacy of pulsed field catheter ablation for symptomatic paroxysmal atrial fibrillation (AF) with that of conventional thermal ablation techniques (radiofrequency or cryoballoon).
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