HCPLive

JANUARY 12, 2024

A survey of more than 3000 US physicians is shedding light on the impact of taking vacation time and avoiding physician-related work on vacation can have on burnout and achieving professional fulfillment.

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Physiologically Speaking

JANUARY 12, 2024

Greetings! Welcome to the Physiology Friday newsletter. This newsletter is brought to you by Examine.com — the best place on the internet for health and nutrition information — and my eBook, “VO2 Max Essentials.” Details can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.

Physiology 120

Physiology BMI Exercise Diet 120

HCPLive

JANUARY 12, 2024

A new study found the risk of Long COVID for short sleepers with pre-existing medical conditions was 3-fold higher than average-length sleepers without pre-existing conditions.

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Med Page Today

JANUARY 12, 2024

(MedPage Today) -- Note that some links may require registration or subscription. In observance of Martin Luther King Day, Morning Break will not be published January 15 and will resume Tuesday January 16. Last year's COVID-19 booster reduced.

Blood Clot 119

Blood Clot COVID-19 Cancer 119

HCPLive

JANUARY 12, 2024

The factors highlighted in this analysis may help dermatologists to better understand the concerns, misconceptions, and perceived risks reported by patients with HS.

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DAIC

JANUARY 12, 2024

milla1cf Fri, 01/12/2024 - 13:03 January 12, 2024 — The Heart Surgeon’s Cookbook is the brainchild of New York-based Cardiovascular and Thoracic Surgeon Dr. Nirav Patel and Fredrik Berselius , holder of two Michelin stars and Founder & Owner of Aska restaurant in New York. They have collaborated with global MedTech provider Getinge to create a cookbook that not only celebrates the physical and mental dexterity of both doctor and chef, but also shares their experiences in precision and mastery o

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HCPLive

JANUARY 12, 2024

Liver transplantation after prolonged preservation with dual hypothermic oxygenated machine perfusion yielded similar outcomes to standard perfusion, showing no compromised donor liver quality and equal safety for recipients.

Transplant 99

Transplant Outcomes 99

Cardiovascular Diabetology

JANUARY 12, 2024

Foot ulcers and/or infections are common long-term complications of diabetes and are associated with increased mortality, especially from cardiovascular disease, though only a few studies have investigated the.

Diabetes 98

Diabetes Cardiovascular Disease Research 98

HCPLive

JANUARY 12, 2024

During a 10-year period, estimated access to drugs increased among Polish patients with rheumatic and musculoskeletal diseases.

Innovation 115

Innovation 115

Cardiovascular Diabetology

JANUARY 12, 2024

The stress hyperglycemia ratio (SHR) has been demonstrated as an independent risk factor for acute kidney injury (AKI) in certain populations. However, this relationship in patients with congestive heart failu.

Heart Failure 98

Heart Failure Risk Factors Research 98

HCPLive

JANUARY 12, 2024

Results suggested bottled alkaline water had no added benefit over tap water for providing alkali content and alkalinizing urine pH.

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Medical Xpress - Cardiology

JANUARY 12, 2024

Researchers from Massachusetts General Hospital (MGH) and Kaiser Permanente have found that communities with high prevalence of adults who fail to exercise in their free-time, experience significantly higher rates of death from cardiovascular disease (CVD), with middle-aged women and elderly Black individuals shouldering the heaviest burden.

Exercise 86

Exercise Cardiovascular Disease Hospital Research 86

HCPLive

JANUARY 12, 2024

Moderate-to-severe anemia decreased the likelihood of a favorable outcome after mechanical thrombectomy compared with no anemia.

Outcomes 98

Outcomes 98

The New England Journal of Medicine

JANUARY 12, 2024

Stella would die without heart surgery, but no one would operate on an active drug user. Perhaps stories like hers can make us question what we mean when we say “get clean.

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European Journal of Heart Failure

JANUARY 12, 2024

Abstract Background Existing data on the association between blood pressure levels and adverse cardiovascular outcomes in patients with heart failure (HF) are inconsistent. The optimal blood pressure targets for patients with HF remain uncertain. This study sought to assess the associations between blood pressure (systolic and diastolic blood pressure, SBP and DBP) levels and adverse cardiovascular disease (CVD) outcomes in patients with HF.

Blood Pressure 81

Blood Pressure Heart Failure Outcomes Cardiovascular Disease 81

Journal of the American Heart Association

JANUARY 12, 2024

Journal of the American Heart Association, Ahead of Print. ABSTRACT: Albuminuria, an established biomarker of the progression of chronic kidney disease, is also recognized as a biomarker for the risk of cardiovascular disease. Elevated urinary albumin excretion indicates kidney damage and systemic vascular disease, including myocardial capillary disease and arterial stiffness.

Cardiovascular Disease 71

Cardiovascular Disease Risk Factors Coronary Artery Disease Kidney Disease 71

HCPLive

JANUARY 12, 2024

A study found when older adults follow a light-moderate or a vigorous physical activity model it is associated with a lower incidence rate ratio of depression.

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Cardiovascular Diabetology

JANUARY 12, 2024

Individuals who are overweight or obese often develop insulin resistance, mediation of the association between body mass index (BMI) and stroke risk through the triglyceride-glucose index (TyG) seems plausible.

BMI 52

BMI Obesity Strokes Stroke 52

HCPLive

JANUARY 12, 2024

Announced on January 9, 2024 by Alcon, the novel dry eye candidate achieved a statistically significant ≥10-mm increase in unanesthetized Schirmer’s score at Day 14.

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Cardiovascular Diabetology

JANUARY 12, 2024

Chen et al. recently related the skin autofluorescence (SAF) of Advanced Glycation End-products to subclinical cardiovascular disease in the 3001 participants from the general population (Rotterdam study), wit.

Cardiovascular Disease 52

Cardiovascular Disease Diabetes 52

Medical Xpress - Cardiology

JANUARY 12, 2024

Despite having a higher risk of experiencing a stroke and being more likely to die from a stroke, Black patients are less likely to receive lifesaving stroke treatments than white patients, a University of Georgia study found.

Stroke 51

Stroke Strokes 51

HCPLive

JANUARY 12, 2024

These data, given sustainability targets in healthcare, may be considered by clinicians and by patients discussing DPIs.

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Journal of the American Heart Association

JANUARY 12, 2024

Journal of the American Heart Association, Ahead of Print. BackgroundDespite the initial evidence supporting the utility of intravascular imaging to guide percutaneous coronary intervention (PCI), adoption remains low. Recent new trial data have become available. An updated study‐level meta‐analysis comparing intravascular imaging to angiography to guide PCI was performed.

Thrombosis 45

Thrombosis Stent Stents Outcomes 45

Circulation

JANUARY 12, 2024

Circulation, Ahead of Print. BACKGROUND:Pulmonary hypertension, characterized by vascular remodeling, currently lacks curative therapeutic options. The dysfunction of pulmonary artery endothelial cells plays a pivotal role in the initiation and progression of pulmonary hypertension (PH). ErbB3 (human epidermal growth factor receptor 3), also recognized as HER3, is a member of the ErbB family of receptor tyrosine kinases.METHODS:Microarray, immunofluorescence, and Western blotting analyses were c

Pulmonary 45

Pulmonary Hypertension Biomarkers Circulation 45

Journal of the American Heart Association

JANUARY 12, 2024

Journal of the American Heart Association, Ahead of Print. BackgroundWe assessed the impact of pre‐ and postprocedural plasma corin levels on the recurrence of atrial fibrillation (AF) after catheter ablation (CA).Methods and ResultsThis prospective, single‐center, observational study included patients undergoing their first CA of AF. Corin was measured before and 1 day after CA.

Atrial Fibrillation 45

Atrial Fibrillation Ablation Risk Factors 45

Circulation

JANUARY 12, 2024

Circulation, Ahead of Print. BACKGROUND:Cardiac transverse tubules (T-tubules) are anchored to sarcomeric Z-discs by costameres to establish a regular spaced pattern. One of the major components of costameres is the dystrophin-glycoprotein complex (DGC). Nevertheless, how the assembly of the DGC coordinates with the formation and maintenance of T-tubules under physiological and pathological conditions remains unclear.METHODS:Given the known role of Ptpn23 (protein tyrosine phosphatase, nonrecept

Cardiomyopathy 45

Cardiomyopathy Physiology Circulation 45

Journal of the American Heart Association

JANUARY 12, 2024

Journal of the American Heart Association, Ahead of Print. BackgroundPulse wave velocity (PWV) is a noninvasive measure of arterial stiffness and predictor of cardiovascular disease. However, the association between PWV and vascular calcification across different vascular beds has not been fully investigated. This study aimed to quantify the association between PWV and multiterritory calcification and to explore whether PWV can identify individuals with vascular calcification beyond traditional

Atherosclerosis 45

Atherosclerosis Aortic valve Aortic Bicuspid/Mitral 45

Medical Xpress - Cardiology

JANUARY 12, 2024

A bivalent mRNA COVID-19 vaccine after receipt of an original monovalent COVID-19 vaccine is effective for preventing COVID-19-related thromboembolic events, according to research published in the Jan. 11 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

COVID-19 40

COVID-19 Research 40

Journal of the American Heart Association

JANUARY 12, 2024

Journal of the American Heart Association, Ahead of Print. BackgroundUltraviolet B (UV‐B) irradiation is an effective treatment for human cutaneous disorders and was shown to reduce experimental atherosclerosis by attenuating immunoinflammatory responses. The aim of this study was to clarify the effect of specific wavelengths of UV‐B on atherosclerosis and the underlying mechanisms focusing on immunoinflammatory responses.Methods and ResultsBased on light‐emitting diode technology, we developed

Atherosclerosis 45

Atherosclerosis Plaque Aortic Technology 45

Stroke Journal

JANUARY 12, 2024

Stroke, Ahead of Print. BACKGROUND:Small dense low-density lipoprotein cholesterol (sdLDL-C) particles are more atherogenic than large and intermediate low-density lipoprotein cholesterol (LDL-C) subfractions. We sought to investigate the association of sdLDL-C and the sdLDL-C/LDL-C ratio with incident carotid plaques with stable and vulnerable morphology in rural China.METHODS:This community-based cohort study used data from the RICAS study (Rose Asymptomatic Intracranial Artery Stenosis), whic

Plaque 40

Plaque Cholesterol Ultrasound Risk Factors 40

Journal of the American Heart Association

JANUARY 12, 2024

Journal of the American Heart Association, Ahead of Print. BackgroundTo explore how differences in local socioeconomic deprivation impact access to aortic valve procedures and the treatment of aortic valve disease, in comparison to other open and minimally invasive surgical procedures.Methods and ResultsProcedure volume data were obtained from the Healthcare Cost and Utilization Project from 18 states from 2016 to 2019 and merged with area deprivation index data, an index of zip code‐level socio

Aortic valve 45

Aortic valve Coronary Artery Bypass Graft Aortic TAVR 45

Stroke Journal

JANUARY 12, 2024

Stroke, Ahead of Print. Background:Patients with severe stroke often rely on surrogate decision-makers for life-sustaining treatment decisions. We investigated ethnic differences between Mexican Americans (MAs) and non-Hispanic White (NHW) individuals in surrogate reports of physician quality of communication and shared decision-making from the OASIS study (Outcomes Among Surrogate Decision Makers in Stroke) project.Methods:Patients had ischemic stroke or intracerebral hemorrhage in Nueces Count

Strokes 40

Strokes Stroke Hemorrhage Outcomes 40

Journal of the American Heart Association

JANUARY 12, 2024

Journal of the American Heart Association, Ahead of Print. BackgroundMitral regurgitation (MR) is the most common valvular disease in the United States and increases the risk of death and hospitalization. The economic burden of MR in the United States is not known.Methods and ResultsWe analyzed inpatient hospitalization data from the 1 221 173 Maryland residents who had any in‐state admissions from October 1, 2015, to September 30, 2019.

Inpatient 40

Inpatient Bicuspid/Mitral Hospital 40

The American Journal of Cardiology

JANUARY 12, 2024

Publication date: Available online 11 January 2024 Source: The American Journal of Cardiology Author(s): Marco Zuin, Gregory Piazza, Gianluca Rigatelli, Claudio Bilato, Amedeo Bongarzoni, Stanislav Henkin, Pietro Zonzin, Franco Casazza, Loris Roncon

Embolism 40

Embolism Pulmonary 40

Journal of the American Heart Association

JANUARY 12, 2024

Journal of the American Heart Association, Ahead of Print. BackgroundObservational studies have suggested the potential role of inflammatory factors in the risk of coronary artery disease (CAD). We aimed to perform 2‐sample Mendelian randomization (MR) analyses to assess the causal association between circulating cytokines/growth factors and CAD.Methods and ResultsThe instrumental variables for 28 circulating cytokines and growth factors were identified from a genome‐wide association study of 82

Coronary Artery Disease 40

Coronary Artery Disease Circulation 40

The American Journal of Cardiology

JANUARY 12, 2024

Publication date: Available online 11 January 2024 Source: The American Journal of Cardiology Author(s): Todd C. Villines, Patricia Rodriguez-Lozano, Indika Mallawaarachchi, Michelle C. Williams, Cole Hirschfeld, Nathan Better, Leslee J. Shaw, Joao V. Vitola, Rodrigo J. Cerci, Sharmila Dorbala, Chiara Bucciarelli-Ducci, Ganesan Karthikeyan, Yosef A.

Coronary Artery Disease 40

Coronary Artery Disease 40

Journal of the American Heart Association

JANUARY 12, 2024

Journal of the American Heart Association, Ahead of Print. BackgroundTelecommunicator CPR (T‐CPR), whereby emergency dispatch facilitates cardiac arrest recognition and coaches CPR over the telephone, is an important strategy to increase early recognition and bystander CPR in adult out‐of‐hospital cardiac arrest (OHCA). Little is known about this treatment strategy in the pediatric population.

Cardiac Arrest 40

Cardiac Arrest Pediatrics Hospital 40