Tue.Nov 05, 2024

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Defibrillation devices can save lives using 1,000 times less electricity

Science Daily - Heart Disease

Researchers used an electrophysiological computer model of the heart's electrical circuits to examine the effect of the applied voltage field in multiple fibrillation-defibrillation scenarios. They discovered far less energy is needed than is currently used in state-of-the-art defibrillation techniques. The authors applied an adjoint optimization method and discovered adjusting the duration and the smooth variation in time of the voltage supplied by defibrillation devices is a more efficient mec

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Survey Highlights Critical Role of Pharmacists in HCV Management

HCPLive

Survey data show pharmacists are integral to HCV screening and treatment across healthcare settings, highlighting their contributions to HCV elimination efforts.

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Top-ranked hospitals for pacemaker placement, by state

Becker's Hospital Review - Cardiology

California and Florida have the most top-ranked hospitals for pacemaker or defibrillator placement in the U. S. , according to the WebMD Choice Awards.

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What's overweight enough for lower disability after stroke?

Science Daily - Stroke

Slightly overweight stroke survivors have a lower risk of sustaining disabilities. New research adds another aspect to the obesity paradox but also highlights the importance of considering the population's normal when recommending best practices.

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Normothermic Machine Perfusion Shows Promise in High-Acuity Liver Transplants

HCPLive

Normothermic machine perfusion in liver transplants improves preservation, reduces early complications, and shows promise in complex cases.

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Advanced heart model can provide patient-specific simulations

Medical Xpress - Cardiology

A team led by researchers at UNC-Chapel Hill have developed an innovative computer model of blood flow in the human heart that promises to transform how we understand, diagnose, and treat heart conditions. This new model, grounded in realistic mathematical descriptions of the heart's anatomy and physiology, successfully captures normal heart function and can predict how the heart responds to different levels of blood flow.

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Phosphatidylethanol Aids Detection of Alcohol Relapse Post-Liver Transplant

HCPLive

Alcohol relapses were detected more frequently after the introduction of phosphatidylethanol in orthotopic liver transplant recipients.

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Antithrombotic Therapy in High Bleeding Risk for Noncardiac Interventions: Key Points

American College of Cardiology

The following are key points to remember from a state-of-the art review on antithrombotic therapy in patients with high bleeding risk (HBR) noncardiac percutaneous interventions from the Working Group of Thrombosis of the Italian Society of Cardiology.

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Study Highlights Limitations of Clinical Pathways for MASLD-Related Hepatocellular Carcinoma

HCPLive

Despite the number of individuals with MASLD-related HCC without cirrhosis who report a low FIB-4, current care pathways may not identify such patients for additional assessments.

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Optimal Timing of Anticoagulation After Acute Ischemic Stroke

American College of Cardiology

The goal of the OPTIMAS trial was to evaluate early compared with late initiation of direct oral anticoagulants (DOACs) among patients with acute ischemic stroke associated with atrial fibrillation.

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Understanding Elafibranor (Iqirvo) for PBC: Insight From New Clinical Trials

HCPLive

Phase 3, 3b, and 4 clinical trials will provide long-term insight into the use of elafibranor in different PBC patient populations and real-world settings.

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New Blood Pressure Target For Individuals at High Risk

American College of Cardiology

Cardiovascular disease (CVD), specifically ischemic heart disease, stroke, and heart failure, is the leading cause of death worldwide.

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Higher heart rate may help spur atrial fibrillation in Black patients

Medical Xpress - Cardiology

An elevated heart rate could provide an important clue to which Black adults often have a dangerous heart rhythm disorder, a new study finds. Higher resting heart rate is associated with increased risk of atrial fibrillation, researchers found.

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Highlights From the 19th Annual Scientific Meeting of the Society of Cardiovascular Computed Tomography in 2024

American College of Cardiology

The 19th Annual Scientific Meeting of the Society of Cardiovascular Computed Tomography (SCCT) was held in July 2024 in Washington, DC.

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Hepatology Month in Review: October 2024

HCPLive

This hepatology month in review spotlights hepatic pipeline news, research on treating and eliminating viral hepatitis, and HCPLive’s coverage of ACG 2024.

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Fungal endocarditis after transcatheter aortic valve implantation complicated with pseudoaneurysm of the ascending aorta

Journal of Cardiothoracic Surgery

Fungal endocarditis following transcatheter aortic valve implantation (TAVI) is a rare and serious complication of this procedure. We describe a case of a 75-year-old patient who developed fungal endocarditis.

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Our revered and mysterious heart

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 06 November 2024; doi:10.1038/s41569-024-01096-w A review of Robin Choudhury’s book The Beating Heart: The Art & Science of Our Most Vital Organ, which explores depictions and perceptions of the heart across millennia.

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Bullectomy with video-assisted thoracic surgery and minimally invasive repair of pectus excavatum simultaneously

Journal of Cardiothoracic Surgery

Pectus excavatum (PE) is the most common chest wall deformity. Surgical treatment with minimally invasive repair (MIRPE) is the most preferred surgical procedure. In the presence of additional pulmonary pathol.

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Do GLP-1 Agonists Really Need to Be Stopped Before Endoscopy?

Med Page Today

(MedPage Today) -- Continuing GLP-1 receptor agonist medications when undergoing an endoscopic procedure appeared safe in a meta-analysis. In pooled findings from nine studies, patients undergoing endoscopy while taking GLP-1 receptor agonists.

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The neo-aortic valve in patients with hypoplastic left heart syndrome is largely preserved: a serial follow-up CMR study

Frontiers in Cardiovascular Medicine

BackgroundIn hypoplastic left heart syndrome (HLHS) patients, neo-aortic valve regurgitation can negatively impact right ventricular (RV) function. We assessed neo-aortic valve function and RV volumetric parameters by analysing serial cardiovascular magnetic resonance (CMR) studies in HLHS patients after completion of total cavopulmonary connection (TCPC).MethodsConsecutive CMR examinations of 80 patients (female: 22) with two (n = 80) or three (n = 45) examinations each were retrospectively ana

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ACCEL Lite: What Aspects of Cardiovascular Care are Most Primed for Disruption with AI?

American College of Cardiology

Patients can benefit from better healthcare access and outcomes by services that are enabled by artificial intelligence (AI). The current state of technology is evolving to now allow diagnosis of advanced conditions from simple diagnostic testing, broadening the scope of early diagnosis and treatment.

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Emergency Department HCV Screening May Reduce Potential Hepatic Complications, Lower Costs

HCPLive

Investigators highlighted the long-term cost-effectiveness of routine HCV screening as well as linkage-to-care for high-risk patients in emergency departments.

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Outcomes of Balloon-Expandable TAVR in Younger Patients

American College of Cardiology

What are outcomes among patients younger than 65 years who received transcatheter aortic valve replacement (TAVR) using a balloon-expandable valve compared to patients aged 65-80 years?

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Low HBsAg Levels During Nucleotide Analog Therapy Brings Favorable Prognostic Outcomes

HCPLive

Chronic hepatitis B patients with HBsAg <100 IU/mL and HBcrAg <3 log U/mL at nucleot(s)ide analog therapy had lower relapse risk.

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Effectiveness and Safety of Atorvastatin vs. Rosuvastatin

American College of Cardiology

What is the real-world effectiveness and safety comparing rosuvastatin and atorvastatin?

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MASEF Score May Top FIB-4, Clinical Screening for Early MASH Detection

HCPLive

MASEF score seemed to be sensitive and effective in detecting at-risk MASH in 2 abstracts presented at the ACG 2024 Meeting.

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Chest Pain – MI Registry: What is the Risk of Ventricular Arrythmia After Primary PCI For STEMI?

American College of Cardiology

A small proportion of patients with STEMI treated via primary PCI experienced late ventricular tachycardia (VT) or ventricular fibrillation (VF), occurring one or more days following the procedure, but late VT or VF with cardiac arrest occurred rarely, especially among patients with uncomplicated STEMI, according to a study published in JAMA Network Open.

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The chaotic beginnings of the tool that made heart surgery possible

Medical Xpress - Cardiology

Over the past century, heart operations that once were unthinkable have become commonplace. Thousands of times a day, surgeons graft arteries, fix structural defects or transplant entire hearts.

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Effects of Sedentary Behavior Reduction and BP in Desk Workers

American College of Cardiology

What is the efficacy of a multicomponent sedentary behavior reduction intervention in reducing resting blood pressure (BP), 24-hour ambulatory BP, and pulse wave velocity (PWV)?

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Men less likely to seek out cardiac care: 5 study takeaways

Becker's Hospital Review - Cardiology

"Study reveals how sociocultural pressures of masculinity impact men's likelihood of seeking cardiac care.

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Younger Patients Undergoing Balloon-Expandable TAVR More Likely to Have Comorbidities, Worse Outcomes at 1-Year

American College of Cardiology

Patients younger than 65 years who received balloon-expandable valve TAVR for severe aortic stenosis during the low-surgical risk era were more likely to have comorbidities and exhibited higher rates of death and readmission at one year vs. patients aged 65 to 80 years, according to a study presented at TCT 2024 and simultaneously published in JAMA Cardiology.

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HCV+ Organs Offer Better Waitlist, Survival Outcomes for Transplantation

HCPLive

Direct-acting antiviral agents have enabled more availability for organ transplant.

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Focus on Heart Failure | Cardiac Amyloidosis: Seek and Ye May Find

American College of Cardiology

Cardiac amyloidosis is becoming increasingly recognized as an etiology for heart failure (HF). Most cases of amyloid cardiomyopathy will fall into one of two categories: light-chain amyloid (AL) amyloidosis resulting from misfolding of monoclonal immunoglobulin light chains or transthyretin amyloidosis with cardiomyopathy (ATTR-CM), due to misfolding of the transthyretin protein.

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Genetic Risk Profile in Aortic Stenosis Compared With Coronary Artery Disease

JAMA Cardiology

This genomewide association study examined specific genetic variants, pathways, and tissues associated with aortic stenosis independent of coronary artery disease in a meta-analysis of participants from 3 European cohorts.

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Cover Story | New Frontiers in Heart Failure Care: Innovations Reshaping Treatment

American College of Cardiology

The idea that obesity increases the risk of heart failure seems like an obvious conclusion. After all, as the Framingham Heart Study clearly showed, obesity and overweight are significantly associated with a higher risk of hypertension, angina and coronary heart disease.

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Transcatheter tricuspid valve replacement aids tricuspid regurgitation

Medical Xpress - Cardiology

For patients with symptomatic and severe or greater tricuspid regurgitation (TR), transcatheter tricuspid valve replacement (TTVR) plus optimal medical therapy (OMT) yields substantial improvement in symptoms, function, and quality of life, according to a study published online Oct. 30 in the Journal of the American College of Cardiology. The research was published to coincide with the annual Transcatheter Cardiovascular Therapeutics conference, held from Oct. 27 to 30 in Washington, D.C.

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Editors’ Corner | Refining Heart Failure Care and Management

American College of Cardiology

In recent years, patients with heart failure (HF) are benefiting more and more from a rapidly evolving management landscape, driven by advances in understanding its pathophysiology along with diagnosis, treatment and personalized care.