Tue.Nov 05, 2024

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Phosphatidylethanol Aids Detection of Alcohol Relapse Post-Liver Transplant

HCPLive

Alcohol relapses were detected more frequently after the introduction of phosphatidylethanol in orthotopic liver transplant recipients.

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Defibrillation devices can save lives using 1,000 times less electricity

Science Daily - Heart Disease

Researchers used an electrophysiological computer model of the heart's electrical circuits to examine the effect of the applied voltage field in multiple fibrillation-defibrillation scenarios. They discovered far less energy is needed than is currently used in state-of-the-art defibrillation techniques. The authors applied an adjoint optimization method and discovered adjusting the duration and the smooth variation in time of the voltage supplied by defibrillation devices is a more efficient mec

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Normothermic Machine Perfusion Shows Promise in High-Acuity Liver Transplants

HCPLive

Normothermic machine perfusion in liver transplants improves preservation, reduces early complications, and shows promise in complex cases.

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What's overweight enough for lower disability after stroke?

Science Daily - Stroke

Slightly overweight stroke survivors have a lower risk of sustaining disabilities. New research adds another aspect to the obesity paradox but also highlights the importance of considering the population's normal when recommending best practices.

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Study Highlights Limitations of Clinical Pathways for MASLD-Related Hepatocellular Carcinoma

HCPLive

Despite the number of individuals with MASLD-related HCC without cirrhosis who report a low FIB-4, current care pathways may not identify such patients for additional assessments.

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Our revered and mysterious heart

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 06 November 2024; doi:10.1038/s41569-024-01096-w A review of Robin Choudhury’s book The Beating Heart: The Art & Science of Our Most Vital Organ, which explores depictions and perceptions of the heart across millennia.

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Understanding Elafibranor (Iqirvo) for PBC: Insight From New Clinical Trials

HCPLive

Phase 3, 3b, and 4 clinical trials will provide long-term insight into the use of elafibranor in different PBC patient populations and real-world settings.

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Hepatology Month in Review: October 2024

HCPLive

This hepatology month in review spotlights hepatic pipeline news, research on treating and eliminating viral hepatitis, and HCPLive’s coverage of ACG 2024.

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The neo-aortic valve in patients with hypoplastic left heart syndrome is largely preserved: a serial follow-up CMR study

Frontiers in Cardiovascular Medicine

BackgroundIn hypoplastic left heart syndrome (HLHS) patients, neo-aortic valve regurgitation can negatively impact right ventricular (RV) function. We assessed neo-aortic valve function and RV volumetric parameters by analysing serial cardiovascular magnetic resonance (CMR) studies in HLHS patients after completion of total cavopulmonary connection (TCPC).MethodsConsecutive CMR examinations of 80 patients (female: 22) with two (n = 80) or three (n = 45) examinations each were retrospectively ana

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Survey Highlights Critical Role of Pharmacists in HCV Management

HCPLive

Survey data show pharmacists are integral to HCV screening and treatment across healthcare settings, highlighting their contributions to HCV elimination efforts.

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Outcomes of Balloon-Expandable TAVR in Younger Patients

American College of Cardiology

What are outcomes among patients younger than 65 years who received transcatheter aortic valve replacement (TAVR) using a balloon-expandable valve compared to patients aged 65-80 years?

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Emergency Department HCV Screening May Reduce Potential Hepatic Complications, Lower Costs

HCPLive

Investigators highlighted the long-term cost-effectiveness of routine HCV screening as well as linkage-to-care for high-risk patients in emergency departments.

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Top-ranked hospitals for pacemaker placement, by state

Becker's Hospital Review - Cardiology

California and Florida have the most top-ranked hospitals for pacemaker or defibrillator placement in the U. S. , according to the WebMD Choice Awards.

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Effectiveness and Safety of Atorvastatin vs. Rosuvastatin

American College of Cardiology

What is the real-world effectiveness and safety comparing rosuvastatin and atorvastatin?

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Low HBsAg Levels During Nucleotide Analog Therapy Brings Favorable Prognostic Outcomes

HCPLive

Chronic hepatitis B patients with HBsAg <100 IU/mL and HBcrAg <3 log U/mL at nucleot(s)ide analog therapy had lower relapse risk.

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Effects of Sedentary Behavior Reduction and BP in Desk Workers

American College of Cardiology

What is the efficacy of a multicomponent sedentary behavior reduction intervention in reducing resting blood pressure (BP), 24-hour ambulatory BP, and pulse wave velocity (PWV)?

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MASEF Score May Top FIB-4, Clinical Screening for Early MASH Detection

HCPLive

MASEF score seemed to be sensitive and effective in detecting at-risk MASH in 2 abstracts presented at the ACG 2024 Meeting.

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Men less likely to seek out cardiac care: 5 study takeaways

Becker's Hospital Review - Cardiology

"Study reveals how sociocultural pressures of masculinity impact men's likelihood of seeking cardiac care.

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HCV+ Organs Offer Better Waitlist, Survival Outcomes for Transplantation

HCPLive

Direct-acting antiviral agents have enabled more availability for organ transplant.

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Vector Field Heterogeneity as a Novel Omnipolar Mapping Metric for Functional Substrate Characterisation in Scar-related Ventricular Tachycardias

HeartRhythm

Vector Field Heterogeneity (VFH) is a novel omnipolar metric to quantify local propagation heterogeneities that may identify functionally critical sites for ablation in scar-related VT.

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Antithrombotic Therapy in High Bleeding Risk for Noncardiac Interventions: Key Points

American College of Cardiology

The following are key points to remember from a state-of-the art review on antithrombotic therapy in patients with high bleeding risk (HBR) noncardiac percutaneous interventions from the Working Group of Thrombosis of the Italian Society of Cardiology.

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Comparative Evaluation of Two Pulsed Field Ablation Systems for Atrial Fibrillation: Insights from Real-World Clinical Implementation and Short-Term Outcomes

HeartRhythm

Pulsed field ablation (PFA) is a safe and effective technology for catheter ablation of atrial fibrillation (AF). Multiple PFA-platforms for AF-ablation have been developed. However, evidence comparing the real-word implementation and performance of different PFA-systems is still limited.

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Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation

American College of Cardiology

The goal of the COAPT trial was to assess the safety and efficacy of transcatheter mitral leaflet approximation using MitraClip among symptomatic heart failure (HF) patients with secondary mitral regurgitation (MR).

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FIRST-IN-HUMAN EXPERIENCE OF HIGH ENERGY ELECTROPULSE PULSED FIELD ABLATION: ACUTE RESULTS FOR PULMONARY VEINS AND POSTERIOR WALL ISOLATION

HeartRhythm

Different iterations of catheter and energy delivery system configurations are evolving for pulsed field ablation (PFA); however, some have used large and complex catheters, required large sheaths and had a recognised risk of haemolysis.

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Younger Patients Undergoing Balloon-Expandable TAVR More Likely to Have Comorbidities, Worse Outcomes at 1-Year

American College of Cardiology

Patients younger than 65 years who received balloon-expandable valve TAVR for severe aortic stenosis during the low-surgical risk era were more likely to have comorbidities and exhibited higher rates of death and readmission at one year vs. patients aged 65 to 80 years, according to a study presented at TCT 2024 and simultaneously published in JAMA Cardiology.

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Does atrial fibrillation ablation prevent cardiovascular death, stroke, and heart failure events?

HeartRhythm

Recent trial results led to a renewed consideration of rhythm control therapy to improve outcomes in patients with atrial fibrillation (AF)1,2. The resulting shift towards rhythm control therapy for most patients with atrial fibrillation is reflected by new recommendations in the recent ESC3 and ACC/AHA/HRS4 AF guidelines. It is likely that the outcome-reducing effects of early rhythm control are mediated by maintenance of sinus rhythm5 and by reducing AF burden6.

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ACCEL Lite: What Aspects of Cardiovascular Care are Most Primed for Disruption with AI?

American College of Cardiology

Patients can benefit from better healthcare access and outcomes by services that are enabled by artificial intelligence (AI). The current state of technology is evolving to now allow diagnosis of advanced conditions from simple diagnostic testing, broadening the scope of early diagnosis and treatment.

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Impact of Race and Ethnicity on the Rhythm Control of Newly Diagnosed Atrial Fibrillation: Insights from the Get With the Guidelines Atrial Fibrillation Registry.

HeartRhythm

An early rhythm control strategy is the preferred management for patients newly diagnosed with atrial fibrillation (AF). A rhythm control strategy, however, has been historically underutilized for patients from underrepresented racial and ethnic groups (UREGs).

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Focus on Heart Failure | Cardiac Amyloidosis: Seek and Ye May Find

American College of Cardiology

Cardiac amyloidosis is becoming increasingly recognized as an etiology for heart failure (HF). Most cases of amyloid cardiomyopathy will fall into one of two categories: light-chain amyloid (AL) amyloidosis resulting from misfolding of monoclonal immunoglobulin light chains or transthyretin amyloidosis with cardiomyopathy (ATTR-CM), due to misfolding of the transthyretin protein.

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Right Ventricular-Pulmonary Arterial Uncoupling as a Predictor of Invasive Hemodynamics and Normotensive Shock in Acute Pulmonary Embolism

The American Journal of Cardiology

Publication date: Available online 4 November 2024 Source: The American Journal of Cardiology Author(s): Eugene Yuriditsky, Robert S. Zhang, Peter Zhang, Radu Postelnicu, Allison A. Greco, James. M Horowitz, Samuel Bernard, Orly Leiva, Vikramjit Mukherjee, Kerry Hena, Lindsay Elbaum, Carlos L. Alviar, Norma M.

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Feature | NCDR Innovates: New Dashboards, CV ASC Registry Suite, More

American College of Cardiology

As the health care field continues to evolve, NCDR is committed to helping facilities measure and improve the quality of care they provide with the most relevant data elements and metrics, actionable insights and more.

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Novel technique and assessment of available three-dimensional delivery sheath for endomyocardial biopsy during cardiac device implantation

HeartRhythm

Early cardiomyopathy diagnosis allows timely treatment and may help resolve problems that occur after cardiac implantable electronic device (CIED) implantation.

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Feature | Spotlight on Chest Pain: ACC’s Tools to Support Clinicians and Patients

American College of Cardiology

ACC's Chest Pain Center Accreditation is designed to help facilities to establish consistent, high-quality processes for the most efficient and effective acute coronary syndrome (ACS) care. For example, Hackensack Meridian JFK University Medical Center made ACS observation process enhancements resulting in an annual cost savings of more than $700K along with reduced length-of-stay.

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Echocardiographic Assessment of Cardiac Remodeling According to Obesity Class

The American Journal of Cardiology

Publication date: Available online 4 November 2024 Source: The American Journal of Cardiology Author(s): Rahil Prajapati, Tingting Qin, Kim A.

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Feature | Designing, Leading and Achieving With ACC’s Quality Summit

American College of Cardiology

Supplying clinicians spanning the entire cardiovascular care team with the tools, resources and insights needed to design, lead and achieve the highest quality care at their institutions was the focus of ACC Quality Summit 2024, held Sept. 17-19 in San Antonio, TX.

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Association of Chronic Kidney Disease and Kidney Failure with Replacement Therapy with Procedural and Long-Term Outcomes after First Generation Watchman Device: Insights from the NCDR LAAO Registry

HeartRhythm

Chronic kidney disease (CKD) and kidney failure with replacement therapy (KFRT) are prevalent in patients with atrial fibrillation (AF).

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Feature | Designing, Leading and Achieving With ACC’s Quality Summit

American College of Cardiology

Several poster presentations on rural health delivery and access to care, offering innovative solutions to increase health equity for cardiovascular patients, were featured at ACC Quality Summit 2024.