DAIC

APRIL 7, 2024

milla1cf Sun, 04/07/2024 - 18:20 April 7, 2024 — An estimated 1 in 5 U.S. adults—and more than 2 in 5 adults aged 60 years and older—have elevated triglycerides, also known as hypertriglyceridemia , putting them at an increased risk for heart attacks and stroke. However, few treatments are currently available for this patient population, until now. A new investigational drug called olezarsen holds promise for substantially reducing triglyceride levels without significant adverse effects, accordi

Cholesterol 116

Cholesterol Heart Attack Heart attacks Myocardial Infarction 116

Med Page Today

APRIL 7, 2024

(MedPage Today) -- ATLANTA -- The SGLT2 inhibitor empagliflozin (Jardiance) did not exactly prevent deaths and heart failure (HF) events when initiated atop other standard therapies for acute myocardial infarction (MI), the EMPACT-HF trial found.

Myocardial Infarction 98

Myocardial Infarction Heart Failure 98

DAIC

APRIL 7, 2024

milla1cf Sun, 04/07/2024 - 18:45 April 7, 2024 — Strategies such as earning points or small amounts of money encouraged people at high risk for heart disease or stroke to increase their daily walking by about 10% and sustain the increase for a year, according to research being presented at the American College of Cardiolog y’s Annual Scientific Session.

Heart Disease 115

Heart Disease Heart Attack Heart attacks Public Health 115

Med Page Today

APRIL 7, 2024

(MedPage Today) -- ATLANTA -- An interatrial shunt failed to provide a clinical benefit to people with heart failure (HF) overall in the RELIEVE-HF trial, though actual harm or benefit seemed to hinge on the patient's left ventricular ejection.

Heart Failure 98

Heart Failure 98

DAIC

APRIL 7, 2024

milla1cf Sun, 04/07/2024 - 18:09 April 7, 2024 — Among patients at high or very high risk for a heart attack or stroke, the addition of the investigational drug lerodalcibep to standard cholesterol-lowering medication for one year reduced LDL, or “bad” cholesterol, levels by more than half on average, compared with a placebo. In addition, 90% of patients treated with lerodalcibep, versus 16% of those on placebo, attained the newer, more stringent guideline-recommended LDL targets set by the Amer

Cholesterol 111

Cholesterol Heart Attack Heart attacks Stroke 111

Med Page Today

APRIL 7, 2024

(MedPage Today) -- ATLANTA -- Weight loss and heart failure benefits with semaglutide (Wegovy) extended to patients with obesity-related heart failure with preserved ejection fraction (HFpEF) who have type 2 diabetes, the STEP-HFpEF DM trial showed.

Preserved Ejection Fraction 96

Preserved Ejection Fraction Diabetes Heart Failure Obesity 96

DAIC

APRIL 7, 2024

milla1cf Sun, 04/07/2024 - 17:57 April 7, 2024 — In patients with severely elevated triglyceride levels at risk for developing acute pancreatitis, the investigational drug plozasiran reduced triglyceride levels by an average of 74% after 24 weeks of use without causing any significant safety concerns, according to research presented at the American College of Cardiology ’s Annual Scientific Session.

Heart Attack 110

Heart Attack Heart attacks Plaque Cholesterol 110

American College of Cardiology

APRIL 7, 2024

Ticagrelor monotherapy following one month of dual antiplatelet therapy (DAPT) outperforms 12-month DAPT (aspirin and ticagrelor) post PCI for reducing clinically meaningful bleeding with no increased thrombotic risk, according to the results of the ULTIMATE-DAPT study, presented during a Late Breaking Clinical Trial session at ACC.24 and published simultaneously in The Lancet.

Article 75

Article 75

The New England Journal of Medicine

APRIL 7, 2024

Transcatheter aortic-valve implantation (TAVI) has become the dominant, if not default, therapy for patients with severe, symptomatic aortic stenosis who are at intermediate, high, or prohibitive risk for surgical aortic-valve replacement (SAVR). Several randomized trials have shown that TAVI in patients at low surgical risk is either noninferior or.

Aortic valve 71

Aortic valve Aortic Stenosis 71

American College of Cardiology

APRIL 7, 2024

The goal of the DanGer Shock trial was to compare the safety and efficacy of Impella CP on top of standard care compared with standard care alone among patients with ST-segment elevation myocardial infarction (STEMI) and cardiogenic shock.

Cardiogenic Shock 74

Cardiogenic Shock Myocardial Infarction STEMI Article 74

NEJM Journal Watch - Cardiology

APRIL 7, 2024

In a randomized, controlled trial, semaglutide resulted in greater weight loss, improved symptoms, and fewer serious adverse events compared with placebo.

Obesity 74

Obesity Diabetes Outcomes 74

American College of Cardiology

APRIL 7, 2024

The goal of the ULTIMATE-DAPT trial was to compare the safety and efficacy of ticagrelor monotherapy compared with dual antiplatelet therapy (DAPT) with aspirin and ticagrelor for 12 months following completion of 1-month DAPT for patients undergoing percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS).

Article 69

Article 69

HCPLive

APRIL 7, 2024

Plozasiran demonstrates a 74% reduction in triglyceride levels at 24 weeks in patients with severe hypertriglyceridemia in the phase 2b SHASTA-2 trial.

64

64

American College of Cardiology

APRIL 7, 2024

The goal of the REDUCE-AMI trial was to evaluate the potential benefit of beta-blockade following acute myocardial infarction (AMI) in patients with preserved left ventricular ejection fraction (LVEF) in the modern era of coronary revascularization and medical therapy.

Myocardial Infarction 66

Myocardial Infarction Article 66

HCPLive

APRIL 7, 2024

Alberto Foà, MD, PhD, discusses a PARAGON-HF analysis from ACC.24 examining treatment-related hypotension in people with HFmrEF/HFpEF.

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69

American College of Cardiology

APRIL 7, 2024

Twelve weeks of daily smartphone messages, designed to cultivate spirituality and promote reflection, was associated with a reduction in systolic blood pressure (BP) and improvement in flow-mediated dilation (FMD).

Blood Pressure 65

Blood Pressure Article 65

Journal of Cardiothoracic Surgery

APRIL 7, 2024

Pulmonary embolism is the most common cardiovascular disease after myocardial infarction and stroke. Konstantinides (Eur Heart J 41(4):543–603, 2020) Current guidelines categorize patients with PE as being at.

Embolism 52

Embolism Pulmonary Myocardial Infarction Cardiovascular Disease 52

American College of Cardiology

APRIL 7, 2024

Long-term treatment with beta-blockers may not lower the risk of death or myocardial infarction (MI) in patients with MI, a preserved left ventricular ejection fraction (LVEF) of ≥50% and coronary artery disease, according to the results of the REDUCE-AMI study, presented during a Late-Breaking Clinical Trial session at ACC.24 and published simultaneously in the New England Journal of Medicine.

Coronary Artery Disease 65

Coronary Artery Disease Myocardial Infarction Article 65

Journal of Cardiothoracic Surgery

APRIL 7, 2024

This study aimed to elucidate the methodology and assess the efficacy of the aortic arch inclusion technique using an artificial blood vessel in managing acute type A aortic dissection (ATAAD).

Aortic 52

Aortic Research 52

American College of Cardiology

APRIL 7, 2024

A substantial gap was found between the self-reports of cardiovascular disease (CVD) by former players in the National Football League (NFL) and a "surprisingly high" prevalence of hypertension, with a "significant discrepancy between participants' awareness and observed disease prevalence," according to the findings.

Risk Factors 63

Risk Factors Cardiovascular Disease Hypertension Article 63

Journal of Cardiothoracic Surgery

APRIL 7, 2024

Although risk factors for unsuccessful Maze procedure have been demonstrated, an appropriate patient selection is still controversial. In our institute, Maze procedure is indicated for those whom normal sinus.

Bicuspid/Mitral 52

Bicuspid/Mitral Risk Factors Research 52

American College of Cardiology

APRIL 7, 2024

Implantation of the Impella CP micro-axial flow pump may increase survival at six months among patients with STEMI complicated by cardiogenic shock (CS), according to the results of the DanGer Shock study.

Cardiogenic Shock 60

Cardiogenic Shock STEMI Article 60

All About Cardiovascular System and Disorders

APRIL 7, 2024

Transcript of the video: Now we will discuss a chest X-ray showing antler sign in pulmonary venous hypertension. For a change, first we will see the picture of a stag, with antlers. You can see the antlers here. So, the shape of the upper lobe vessels in venous hypertension, pulmonary venous hypertension, will be resembling the antlers of the stag. That is why, the name antler sign has been given.

Pulmonary 52

Pulmonary Hypertension General Cardiology 52

American College of Cardiology

APRIL 7, 2024

The increasing need for cardiovascular clinicians to be equipped with the business know-how to navigate the rapidly evolving practice landscape is the focus of the Business of Cardiology Intensive Sessions at ACC.24.

Article 60

Article 60

Frontiers in Cardiovascular Medicine

APRIL 7, 2024

Congenital heart disease is a prevalent birth defect, accounting for approximately one-third of major birth defects. The challenge lies in early detection, especially in underdeveloped medical regions where a shortage of specialized physicians often leads to oversight. While standardized chest x-rays can assist in diagnosis and treatment, their effectiveness is limited by subtle cardiac manifestations.

Congenital Heart Disease 52

Congenital Heart Disease Congenital Heart Disease Ultrasound 52

American College of Cardiology

APRIL 7, 2024

Drs. Kim Eagle, Dharam Kumbhani, Payal Kohli, and Ajay Kirtane debate and discuss the outcomes of the trials presented on day 2 at ACC.24 including REDUCE-AMI (0:35), DanGer-Shock (3:28), ULTIMATE-DAPT (6:17), and TACT2 (10:04).

Outcomes 58

Outcomes Article 58

Frontiers in Cardiovascular Medicine

APRIL 7, 2024

Transcatheter aortic valve replacement (TAVR) has increasingly become a safe, feasible, and widely accepted alternative surgical treatment for patients with severe symptomatic aortic stenosis. However, the incidence of conduction abnormalities associated with TAVR, including left bundle branch block (LBBB) and high-degree atrioventricular block (HAVB), remains high and is often correlated with risk factors such as the severity of valvular calcification, preexisting conditions in patients, and pr

Aortic valve 52

Aortic valve Aortic TAVR Risk Factors 52

All About Cardiovascular System and Disorders

APRIL 7, 2024

Transcript of the video: Now I am going to describe Ashman Phenomenon in atrial fibrillation, which is responsible for a long and short sequence followed by a wide QRS, in atrial fibrillation noted on ECG, which may resemble a ventricular ectopic beat. This is the diagrammatic representation of Ashman phenomenon. You have sequences of AF beats, and a long cycle occurs, followed by a short cycle.

Atrial Fibrillation 52

Atrial Fibrillation Tachycardia General Cardiology 52

Med Page Today

APRIL 7, 2024

(MedPage Today) -- ATLANTA -- Cardiology's bid to escape what many see as burdensome requirements for board certification maintenance under the American Board of Internal Medicine (ABIM) is well underway, a panel reported at the American College.

Certification 52

Certification 52

HCPLive

APRIL 7, 2024

Muthiah Vaduganathan, MD, MPH, discusses a presentation from ACC.24 assessing the effects of dapagliflozin across a range of left ventricular hypertrophy from DELIVER.

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52

American College of Cardiology

APRIL 7, 2024

Edetate disodium-based chelation does not lead to improved outcomes in patients with diabetes who had previously suffered a myocardial infarction (MI), according to the results of the TACT2 study, presented during a Late-Breaking Clinical Trial session.

Myocardial Infarction 56

Myocardial Infarction Outcomes Diabetes Article 56

HCPLive

APRIL 7, 2024

REDUCE-AMI concluded beta-blockers show no significant benefit following myocardial infarction among patients with normal left ventricular ejection fraction

Myocardial Infarction 52

Myocardial Infarction 52

American College of Cardiology

APRIL 7, 2024

Generous contributions from ACC members around the world are helping to develop solutions for some of the biggest challenges of today, including inspiring and encouraging the next generation of leaders, educators, clinicians and scientists and tangibly addressing the global burden of cardiovascular disease.

Education 56

Education Cardiovascular Disease Article 56

HeartRhythm

APRIL 7, 2024

Atrial fibrillation (AF), already the most prevalent clinical arrhythmia, is increasing in prevalence1. It is associated with adverse outcomes that significantly impact the quality of life (QoL) experienced by patients. Thus, the accurate evaluation of QoL is an emerging part of the assessment of AF patients2. Several tools have arisen to evaluate clinically relevant endpoints.

Atrial Fibrillation 40

Atrial Fibrillation Quality of Life Outcomes Arrhythmia 40

American College of Cardiology

APRIL 7, 2024

The goal of the TACT2 trial was to determine the potential clinical benefit of the chelating agent edetate disodium (EDTA) in older adults with a history of myocardial infarction (MI) and diabetes mellitus (DM).

Myocardial Infarction 53

Myocardial Infarction Diabetes Article 53

The New England Journal of Medicine

APRIL 7, 2024

Current international clinical practice guidelines recommend complete revascularization for patients with ST-segment elevation myocardial infarction (STEMI) with multivessel coronary artery disease1 on the basis of evidence from randomized, controlled trials.2 The COMPLETE trial (Complete versus Culprit-Only Revascularization Strategies to Treat Multivessel Disease after Early PCI for.

Myocardial Infarction 40

Myocardial Infarction Physiology STEMI 40

American College of Cardiology

APRIL 7, 2024

The goal of the SMART trial was to evaluate a self-expanding valve compared with a balloon-expandable valve among patients with aortic stenosis and a small aortic annulus undergoing treatment with transcatheter aortic valve replacement (TAVR).

Aortic valve 53

Aortic valve TAVR Aortic Stenosis 53