Wed.Jan 29, 2025

article thumbnail

Fluctuating Cholesterol Tied to Higher Dementia Risk

Med Page Today

(MedPage Today) -- Year-to-year fluctuations in total cholesterol and low-density lipoprotein cholesterol (LDL-C) levels were tied to higher risks of cognitive decline and dementia, a study of nearly 10,000 older adults showed. Participants with.

article thumbnail

More Americans than ever are confident about providing lifesaving CPR, new survey suggests

American Heart News - Heart News

DALLAS, January 29, 2025 When someone's heart stops pumping, early CPR can save their life.[1] New survey research from the American Heart Association reveals more Americans are prepared to provide that lifesaving rhythm for their friends, family.

Research 113
article thumbnail

FDA Clears IND for Frevecitinib Asthma Inhaler

HCPLive

Frevecitinib is a novel inhaled dry powder therapeutic in development for asthma that remains inadequately controlled by SOC inhaled maintenance therapies.

112
112
article thumbnail

Stem-cell 'heart patch' shows promise for heart failure treatment

Medical Xpress - Cardiology

Results from rhesus macaques provide solid ground for a first-in-human investigation of heart repair with stem cell-derived engineered heart muscle. The study is a milestone for the clinical application of the "heart patch" as an innovative treatment option for patients with advanced heart failure at the University Medical Center Gttingen (UMG) and University Medical Center Schleswig-Hostein, Canpus Lbeck (UKSH).

article thumbnail

What went on during Covid?

Dr. Malcolm Kendrick

Brevity? [Not my strong point] Today, it is almost as if it never happened. The time of COVID-19 (which I shall simply call Covid from here on). It came, it went, it is now ancient history. Hardly anyone wants to talk about it anymore. Why not? I suppose you could say, whats the point? You cant do anything about it. What is done, is done. True, but maybe you can help to prevent most damaging things from happening again.

COVID-19 113
article thumbnail

Heatstroke may lead to chronic heart disease and obesity, mouse model suggests

Medical Xpress - Cardiology

Every year, more than 100,000 people are treated for heat injury in the U.S., a number that's been rising as the world rapidly warms. Heatstroke, the most damaging form, can make people lose consciousness, suffer organ injury, and on occasion, even die.

article thumbnail

Sodium Consumption Associated with Greater Odds of Developing Psoriasis

HCPLive

In this analysis, investigators explored whether dietary sodium intake was linked with psoriasis and whether any subgroups of patients were more likely to report salt-sensitive psoriasis.

95

More Trending

article thumbnail

Why Mechanical AVR Valves Still Matter

CardiacWire

A presentation at this years Society of Thoracic Surgeons (STS) conference suggests mechanical valves might lead to better survival compared to bioprosthetic valves in patients aged 60 or younger undergoing SAVR even though it seems like theyre going out of style. Mechanical SAVR valves have been around in one form or another since the 1960s, but have fallen out of favor in recent years.

BMI 80
article thumbnail

EXIT-HF: Clinical Impact of Center- vs. Home-Based Cardiac Rehab

American College of Cardiology

Home-based cardiac rehabilitation was found to be noninferior to traditional center-based programs, supporting the home-based approach as an effective and feasible alternative for patients with well-treated heart failure (HF).

article thumbnail

New tool predicts stroke outcome with 93% accuracy, guiding better carotid surgery decisions

Medical Xpress - Cardiology

Stroke remains a global health challenge, ranking second in worldwide mortality and fifth in U.S. deaths. In response, researchers at Ochsner Health, led by Hernan Bazan, MD, DFSVS, FACS, have developed a predictive model with a 93% accuracy rate in determining whether urgent carotid-intervention patients will regain functional independence. This study, "Precision in Stroke Care: A Novel Model for Predicting Functional Independence in Urgent Carotid Intervention Patients," is now available in th

Stroke 74
article thumbnail

ICM Implantation and Remote Follow‐Up Management by Trained Nurses in Italian Hospitals: Current Practice and Nurse Feedback

Journal of Cardiovascular Electrophysiology

Key results of the survey about nurse-led implantable cardiac monitor management practices in Italy. ABSTRACT Aims This project aimed to evaluate current practices of trained nurses performing implantable cardiac monitor (ICM) implantations and remote follow-ups in Italy, assessing hospital protocols and nurses' perceptions. Methods An anonymous survey was conducted among 163 trained nurses across 75 Italian hospitals, focusing on their ICM implantation and remote monitoring practices.

Nursing 72
article thumbnail

Comprehensive review of myocardial injury after noncardiac surgery: prevention, intervention, and long-term management strategies

Journal of Cardiothoracic Surgery

Myocardial Injury after Noncardiac Surgery (MINS) is an increasingly recognized complication that significantly impacts postoperative morbidity and mortality. Characterized by elevated cardiac troponin levels.

69
article thumbnail

ACC Study Evaluates LGBTQ+ CV Workforce

American College of Cardiology

Further work is necessary in the cardiology field to create a safe and inclusive space for cardiovascular lesbian, gay, bisexual, transgender and queer (LGBTQ+) trainees and physicians, as well as LGBTQ+ patients at risk for cardiovascular disease.

article thumbnail

Acupuncture combined with multiple therapies for angina pectoris: a systematic review and network meta-analysis

Frontiers in Cardiovascular Medicine

ObjectiveAcupuncture combined with multiple treatment modalities has been widely employed for treating angina pectoris. This paper compared the efficacy of acupuncture combined with multiple treatment modalities for angina pectoris by network meta-analysis (NMA).MethodsAs of November 2023, this study searched eight electronic databases for randomized controlled trials (RCTs) of acupuncture combined with multiple modalities for the treatment of angina pectoris based on antianginal therapies.

Angina 64
article thumbnail

Novel cardiovascular risk score uses stress test to predict heart disease more accurately

Medical Xpress - Cardiology

A study by Emory cardiovascular researchers has paved the way for the development of a new cardiovascular reactivity risk score that could better identify and improve how quickly high-risk patients under high stress are diagnosed and begin to receive treatment for heart disease.

article thumbnail

JACC: CardioOncology Expert Panel Addresses CV Care After Cancer Therapy

American College of Cardiology

An expert panel report, the last of three in a special series published in JACC: CardioOncology, focuses on evaluating the current evidence and highlighting gaps in both evidence and guideline recommendations for managing cardiovascular disease in cancer survivors who have completed cancer therapy.

Cancer 63
article thumbnail

Industry marketing payments to physicians and prescription patterns for sacubitril/valsartan in the USA

Heart BMJ

Objectives Although financial interactions between physicians and pharmaceutical and medical device companies could be potential conflicts of interest, in certain instances, industry promotion targeted at physicians may facilitate the early adoption of effective, novel care for patients such as sacubitril/valsartan in the USA. This study aims to evaluate associations between industry-sponsored meal payments to physicians and their prescribing patterns for sacubitril/valsartan in the USA.

article thumbnail

Sports and Exercise Cardiology: Highlights From the 2024 American Heart Association Scientific Sessions

American College of Cardiology

The 2024 American Heart Association (AHA) Scientific Sessions in Chicago featured programming related to sports cardiology and exercise. Highlights included a dedicated sports cardiology educational session, Cardiac Evaluation in the Athlete: When Should I Worry?

article thumbnail

Circulating bone morphogenetic protein 10 as a novel marker of atrial stress and remodelling in heart failure

Heart BMJ

Background We evaluated the potential of circulating bone morphogenetic protein 10 (BMP10) as a biomarker for atrial stress and remodelling in patients with heart failure (HF), in comparison to N-terminal pro-B-type natriuretic peptide (NT-proBNP). We also assessed the predictive value of BMP10 for adverse clinical outcomes. Methods BMP10 levels were quantified in 2085 chronic HF patients from the European BIOlogy Study to TAilored Treatment in Chronic Heart Failure (BIOSTAT-CHF) cohort and in 1

article thumbnail

FDA Grants 510(k) Clearance to First Lp(a) Blood Test in Molar Units

HCPLive

Awarded to Roche, the Tina-quant Lipoprotein (a) Gen.2 Molarity assay will be the first 510(k) cleared test measuring Lp(a) in nanomoles per liter (nmol/L).

59
article thumbnail

Age-stratified comparison of heart age and predicted cardiovascular risk in 370 000 primary care patients

Heart BMJ

Background Cardiovascular disease (CVD) preventive medications are recommended for patients at high short-term CVD risk. As most younger people with multiple raised CVD risk factors levels have low short-term risk, they could be falsely reassured to take no action. Heart age—the chronological age of a hypothetical person with the same short-term absolute CVD risk as the patient being assessed, but with an ‘ideal’ risk profile—is a complementary relative CVD risk metric de

article thumbnail

The Paralyzed Stomach During Migraine Attacks: How to Treat Migraine with Gastroparesis

HCPLive

Gastroparesis during migraine attacks can hinder oral medication absorption. Migraine experts discuss the connection between gastroparesis and migraine.

59
article thumbnail

Prevalence and relevance of H558R in the efficacy and toxicity of flecainide in patients with atrial fibrillation: a cohort study

Heart BMJ

Background The SCN5A gene polymorphism histidine-558-to-arginine (H558R) has been associated with atrial fibrillation (AF) and may affect the therapeutic effects of flecainide. This study aimed to assess the prevalence of the H558R polymorphism in a European cohort of patients with AF and examine its association with flecainide’s effects on AF recurrence and toxicity.

article thumbnail

Study Shows Medtronic ICM Accurately Predicts Risk Thresholds for AFib Patients Using AI

DAIC

tim.hodson Wed, 01/29/2025 - 13:02 Jan. 16, 2025 Primary results from the DEFINE AFib clinical study show the Medtronic LINQ family of insertable cardiac monitors (ICM), paired with a novel algorithm, were able to detect atrial fibrillation episodes and properly risk stratify patients as high risk prior to an AF-related healthcare utilization 80% of the time.

AFIB 52
article thumbnail

Improving antiarrhythmic therapy for patients with atrial fibrillation using common genetic variants

Heart BMJ

Many medical specialties have already integrated genetic variants into their clinical decision-making and therapeutic management. While genetic diagnoses take centre stage in clinics for inherited cardiac conditions, common cardiovascular variants still linger in the shadows. The observational cohort study by Trancado et al examines the efficacy and toxicity of flecainide for rhythm control therapy of atrial fibrillation (AF) depending on a common gene polymorphism in the SCN5A gene, histidine-5

article thumbnail

How To Show Your Heart Some Love This February

AMS Cardiology

We often associate the month of February with hearts because of Valentines Day. However, there is another reason we should think of hearts in February its American Heart Month, a designated time to advocate for cardiovascular health and raise awareness about heart disease. According to the Centers for Disease Control and Prevention (CDC), one person dies every 34 seconds from heart disease, making this disease the leading cause of death for both men and women of most racial and ethnic groups in

article thumbnail

New wearable cardiac acoustic monitoring technology for evaluation of subclinical leaflet thrombosis after transcatheter aortic valve replacement

Heart BMJ

Background Subclinical leaflet thrombosis (SLT) is a common complication after transcatheter aortic valve replacement (TAVR). Multidimensional CT (MDCT) is the main imaging mortality for the diagnosis of SLT but it enhances the risk of contrast-induced nephropathy. Our study aimed to use an innovative wearable acoustic cardiography (ACG) device to diagnose SLT as an alternative option.

article thumbnail

Toward a New SUMMIT in Heart Failure with Preserved Ejection Fraction

The New England Journal of Medicine

Treatment options for heart failure with preserved ejection fraction have historically been limited. In a 2016 review of this condition in the Journal, treatment recommendations focused on diuretics, exercise training, and management of coexisting conditions.1 The years since that publication have seen the notable emergence of.

article thumbnail

Clot-in-transit and pulmonary embolism: an urgent call for awareness and action

Heart BMJ

Patients with acute pulmonary embolism (PE) have a wide spectrum of clinical presentations, from incidental findings to sudden cardiac death. Management and treatment recommendations in currently available guidelines vary according to patient risk and haemodynamic profile. A clot-in-transit (CiT) in the right heart chambers may be occasionally identified and is, therefore, an under-recognised but challenging condition, often preceding an abrupt clinical deterioration, and associated with increas

article thumbnail

Continuation versus Interruption of Oral Anticoagulation during TAVI

The New England Journal of Medicine

In a randomized trial involving patients undergoing TAVI, periprocedural continuation of oral anticoagulation was not noninferior to interruption of this therapy with respect to adverse events at 30 days.

57
article thumbnail

Heart age tools are good for raising awareness, but bad for shared decision-making about medication

Heart BMJ

There is something compelling about being told that your heart age is older than your actual age. For this reason, heart age calculators are both numerous and popular, reaching millions of users worldwide. 1 They can be an effective way to engage the general public with an interesting ‘call to action’ in health promotion campaigns, including younger people who may be less aware of heart disease prevention. 2 3 However, a careful review of the evidence shows they are not the magic bul

article thumbnail

Cost-effectiveness of Polypills, Obesity and FH, Adverse Pregnancy Outcomes and Long-term HF Risk

American College of Cardiology

In this weeks View, Dr. Eagle examines the cost-effectiveness of polypills. He then discusses overweight and obesity in patients with familial hyperlipidemia.

Obesity 56
article thumbnail

Decoding dyspnoea: fluoroscopy of prosthetic valve dynamics in a young patient

Heart BMJ

Clinical introduction A patient in his 40s presented with progressive dyspnoea, worsening from New York Heart Association (NYHA) Class II for the past 6 months to NYHA Class III over the past month. The medical history includes hypertension and a Bentall’s procedure (St. Jude’s bileaflet mechanical prosthetic valve) with hemiarch repair 5 years ago for severe aortic regurgitation secondary to an acute type A aortic dissection.

article thumbnail

Association between the atherogenic index of plasma and long-term risk of type 2 diabetes: a 12-year cohort study based on the Japanese population

Cardiovascular Diabetology

Atherosclerotic dyslipidemia is associated with an increased risk of type 2 diabetes (T2D). Although previous studies have demonstrated an association between the atherogenic index of plasma (AIP) and insulin.

article thumbnail

Endovascular management of a spontaneous aorto-caval fistula resulting from abdominal aortic aneurysm: case report and literature review

Frontiers in Cardiovascular Medicine

BackgroundAorto-caval fistula is a rare complication of abdominal aortic aneurysms that can occur spontaneously, iatrogenically, or traumatically, associated with high morbidity and mortality. Endovascular stent graft repair represents a practical approach to managing this fatal condition.Case presentationA 75-year-old male patient was admitted to the nephrology department of our hospital, complaining of acute back pain, hematuria, and repeated vomiting for one week.

article thumbnail

Cardiac imaging and AI: 5 things to know

Becker's Hospital Review - Cardiology

"Discover the latest scientific statement from seven radiological organizations on the use of AI in cardiac imaging, including technology readiness levels and s

article thumbnail

Radiofrequency ablation vs. cryoablation for pediatric atrioventricular nodal reentrant tachycardia in the era of three-dimensional electroanatomical mapping

Frontiers in Cardiovascular Medicine

BackgroundCryoablation for pediatric atrioventricular nodal reentry tachycardia (AVNRT) is favored for reducing conduction system injury compared to radiofrequency (RF) ablation. The safety advantage of cryoablation over RF ablation primarily results from studies conducted without a three-dimensional electroanatomical mapping (3D EAM) system. Currently, 3D EAM systems offer precise and efficient guidance, improving safety and outcomes.