Wed.Nov 06, 2024

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Early-Life Sugar Restriction Reduced Diabetes, Hypertension Risk

Med Page Today

(MedPage Today) -- SAN ANTONIO -- Limiting exposure to sugar starting in utero reduced risk and delayed onset of type 2 diabetes and hypertension in adulthood, a study showed. Adults exposed to early-life sugar rationing in the U.K. for at least.

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Five minutes of extra exercise a day could lower blood pressure

Science Daily - Heart Disease

New research suggests that adding a small amount of physical activity -- such as uphill walking or stair-climbing -- into your day may help to lower blood pressure.

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Phase 3 Data Shows TEV-‘749 Injection Improves Social Function in Schizophrenia

HCPLive

Teva presents 2 findings at Psych Congress 2024: TEV’749’s effects on social function and quality of life in adults with schizophrenia and risperidone adherence patterns.

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Boston Scientific Bolsters AFib Mapping with Cortex Acquisition

CardiacWire

Boston Scientific made what could become a major addition to its electrophysiology portfolio, acquiring AFib mapping startup Cortex, Inc. for an undisclosed sum. Cortex gives Boston Scientific a new mapping technology that detects AFib signs and triggers outside of the pulmonary veins, and can help EP teams develop ablation strategies for more complex AFib cases.

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Epigenomic biomarkers of cardiometabolic disease: How far are we from daily practice?

Cardiovascular Diabetology

Determining whether someone has cardiometabolic disease (CMD), especially in the early stages, can be complicated. Risk stratification ordinarily depends on an extended process relying on medical history that.

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Monica Kraft, MD: Discussing Phase 3b Findings on Albuterol/Budesonide for Asthma

HCPLive

This interview with Kraft features a discussion regarding her team’s new data from the BATURA study on albuterol for patients’ asthma exacerbations.

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Mixed Bag for Clinicians Vying for House Seats

Med Page Today

(MedPage Today) -- The presidential election was not the only race on Tuesday -- the seats for all 435 members of the House were also up for grabs. See below how some of the healthcare-affiliated non-incumbent candidates fared, according to results.

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Study shows how high blood sugar increases risk of thrombosis

Medical Xpress - Cardiology

A study conducted at the Center for Research on Redox Processes in Biomedicine (Redoxoma) helps understand how high blood sugar (hyperglycemia), one of the manifestations of diabetes, can cause thrombosis. The findings, reported in an article published in the Journal of Thrombosis and Haemostasis, can contribute to the development of strategies to prevent cardiovascular dysfunction in diabetics.

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Atorvastatin vs. Rosuvastatin: Do Effectiveness and Safety Differ?

NEJM Journal Watch - Cardiology

In this observational study, rosuvastatin was associated with lower 6-year mortality but interpreting and applying the results is not straightforward.

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Study reveals how cancer immunotherapy may cause myocarditis in some patients

Medical Xpress - Cardiology

Some patients being treated with immune checkpoint inhibitors, a type of cancer immunotherapy, develop a dangerous form of heart inflammation called myocarditis.

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Work-Related Stress Linked to Poor Cardiovascular Health in US Adults

HCPLive

Work-related stress associated with adverse cardiovascular health in diverse US adult population, indicating potential risk factor for CVD prevention.

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Left atrial strain in patients without cardiovascular disease: uncovering influencing and related factors

Cardiovascular Ultrasound

Despite its proven prognostic value in different contexts, the precise implications of left atrial strain (LAS) assessment throughout different phases of the atrial cycle remain uncertain. A direct correlation.

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Case Report: Increase in wall shear stress in a narrowed true lumen after type A aortic dissection repair analyzed by computed fluid dynamics

Frontiers in Cardiovascular Medicine

A 46-year-old man suffered from acute type A aortic dissection (TAAD) and underwent total arch replacement using the frozen elephant trunk (FET) procedure. During follow-up, we noted back pain and found distal stent graft-induced new entry (dSINE) at the FET distal part by computed tomography. We performed additional extended thoracic endovascular aortic repair (TEVAR) for this pathology.

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Mazen Noureddin, MD: Differences in Resmetirom Efficacy Based on Body Weight, BMI

HCPLive

Noureddin explains the efficacy of resmetirom doses and how they vary based on patients’ body weight and BMI, supporting current prescribing practices.

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Modified fenestrated/branched endovascular aortic repair with short bridging stent to treat complex aortic dissection

Frontiers in Cardiovascular Medicine

ObjectivesThis study aims to improve fenestrated/branched endovascular aortic repair (F/B EVAR) through fabricating physician-modified stent grafts (PMSG) with short bridging stent to treat complex aortic dissection.MethodsFrom November 2018 to January 2024, a total of 82 aortic dissection patients were treated by F/B EVAR combined with short bridging stents, including 19 aortic arch dissection patients and 63 thoracoabdominal aortic dissection patients.

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Data suggest work-related stress compromises cardiovascular health

Medical Xpress - Cardiology

In a large multi-ethnic group of adults in the United States without cardiovascular disease, those with work-related stress were more likely to have unfavorable measures of cardiovascular health. The findings are published in the Journal of the American Heart Association.

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H-NMR metabolomics identifies three distinct metabolic profiles differentially associated with cardiometabolic risk in patients with obesity in the Di@bet.es cohort

Cardiovascular Diabetology

Obesity is a complex, diverse and multifactorial disease that has become a major public health concern in the last decades. The current classification systems relies on anthropometric measurements, such as BMI.

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Group clashes in pulmonary hypertension

Dr. S. Venkatesan MD

PH is an important clinical cardio-pulmonary entity , which we confront day to day. Though the prevalence of PH in a community is just 1 % (25 times less than systemic hypertension) it deserves a special place as the diagnosis is more complex and outcome is often adverse. The defining criteria , the classification, and grading of PH has always been a difficult and dynamic academic task.Right from WHO’s 1974 definition, we have 7 global symposiums , last one happened few months ago, in July

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Changes in the estimated glucose disposal rate and incident cardiovascular disease: two large prospective cohorts in Europe and Asia

Cardiovascular Diabetology

Previous study found that estimated glucose disposal rate (eGDR) was significantly associated with cardiovascular disease (CVD). However, little is known about the change in eGDR over time and its association.

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How breast cancer screening can identify CVD risk

Becker's Hospital Review - Cardiology

Breast arterial calcifications are benign calcium buildups that in mammograms look like white parallel lines. Measuring these calcifications may improve cardiovascular risk in women, according to a study published Sept. 27 in JACC: Advances.

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ZIP7 contributes to the pathogenesis of diabetic cardiomyopathy by suppressing mitophagy in mouse hearts

Cardiovascular Diabetology

Although the exact role of mitophagy in the pathogenesis of diabetic cardiomyopathy (DCM) caused by type 2 diabetes mellitus (T2DM) remains controversial, recent studies revealed inhibition of mitophagy exacer.

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Secondary MR and Percutaneous Interventions: Key Points

American College of Cardiology

The following are key points to remember from a state-of-the-art review on treatment options for patients with secondary mitral regurgitation (SMR).

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Empowering hearts: advancing cardiovascular research for women’s health

The British Journal of Cardiology

Cardiovascular disease remains the leading cause of death for women, responsible for over a third of all deaths. 1 In contrast, women remain widely under-represented in cardiovascular trials, 2 as well as in their roles as physicians and trialists. 3 The scarcity of female representation in cardiology carries broad consequences, affecting patient care quality, workplace diversity, and the inclusion of women in clinical trials.

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Phase 3 Data Shows Lumateperone Delays Schizophrenia Relapse Longer Than Placebo

HCPLive

Phase 3 data shows lumateperone 42 mg significantly delayed relapse in patients with schizophrenia vs placebo, with 63% reduced relapse risk and good tolerance.

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Pre-Hospital Randomized Trial of Medication Route in Out-of-Hospital Cardiac Arrest

American College of Cardiology

The goal of the PARAMEDIC-3 trial was to compare the efficacy and safety of an initial vascular access strategy of intraosseous (IO) versus peripheral intravenous (IV) access for medication administration in out-of-hospital cardiac arrest.

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Allergy Month in Review | October 2024

HCPLive

In this review of the month of October, some of the most notable advancements and news in the field of allergy were highlighted.

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American Heart Association to honor 8 cardiology leaders

Becker's Hospital Review - Cardiology

The American Heart Association will recognize eight leaders in cardiology at the organization's annual Scientific Sessions conference, set for Nov. 16-18.

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Nephrology Month in Review: October 2024

HCPLive

This nephrology month in review spotlights HCPLive’s coverage of ASN Kidney Week, the debut of a new podcast, and new research on IgA nephropathy.

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SGLT2 inhibitors: between the zeal of the clinical studies and the challenges of the day-to-day practice

The British Journal of Cardiology

Sodium-glucose cotransporter type 2 inhibitors (SGLT2i) have demonstrated efficacy in reducing cardiovascular deaths and hospitalisations associated with heart failure patients. Despite well-established benefits observed in clinical trials, their real-world application remains underexplored. The purpose of this quality improvement project was to investigate and address the gap between evidence-based guidelines and the practical application of SGLT2i therapy in patients with heart failure with re

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Filgotinib Continues to Show Efficacy for RA in LTE Studies

HCPLive

Week 156 efficacy and safety data from the FINCH 4 study are consistent with that seen in FINCH 1, 2, and 3.

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Devising and delivering the UK’s first nurse-led cardiac catheter laboratory radial access programme

The British Journal of Cardiology

Traditionally, radial artery access (RAA) has been an exclusively ‘physician-delivered’ service, but with adequate training, nurse-led arterial cannulation can become widely adopted. In this clinical audit, senior nursing practitioners with at least two years of catheter lab experience, were offered RAA training. In phase 1 of training, two nurses were initially familiarised with a well-structured training protocol.

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FDA Accepts BLA for Denosumab Biosimilar

HCPLive

If approved, HLX14 would follow the first 2 denosumab biosimilar approvals in March 2024.

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TAVR in Younger Patients; Atorvastatin vs. Rosuvastatin; Sedentary Behavior and Blood Pressure

American College of Cardiology

In this week’s View, Dr. Eagle looks at the outcomes of balloon-expandable transcatheter aortic valve replacement (TAVR) in younger patients.

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Tricuspid transcatheter edge-to-edge repair explored in severe tricuspid regurgitation

Medical Xpress - Cardiology

For patients with symptomatic and severe tricuspid regurgitation (TR), tricuspid transcatheter edge-to-edge repair (T-TEER) yields significant improvements in primary end points, according to a study published online Oct. 27 in the Journal of the American College of Cardiology to coincide with the annual Transcatheter Cardiovascular Therapeutics conference, held from Oct. 27 to 30 in Washington, D.C.

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Outcomes of Intravascular Lithotripsy-Assisted Transfemoral TAVR

American College of Cardiology

What are the contemporary characteristics, trends, and outcomes of intravascular lithotripsy (IVL)-assisted transfemoral (TF) transcatheter aortic valve replacement (TAVR) in the United States?

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Additional value of venous flow pattern for ultrasound-guided venous closure with suture-mediated vascular closure device

HeartRhythm

We read with great interest the article titled, “Feasibility and efficacy of real-time ultrasound-guided venous closure with suture-mediated vascular closure device,” by Tachi et al.1 who evaluated suture-mediated vascular closure device (VCD) foot movement in real-time using ultrasound to confirm the contact with the anterior wall and avoid injury or ligation of the posterior wall or branch.

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Intravenous vs. Intraosseous Vascular Access During Out-of-Hospital Cardiac Arrest

American College of Cardiology

The goal of the IVIO trial was to compare the efficacy and safety of an initial vascular access strategy of intraosseous (IO) versus peripheral intravenous (IV) access for medication administration in nontraumatic out-of-hospital cardiac arrest.