Wed.Nov 06, 2024

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Using a fan and wetting the skin reduces risk of deadly cardiac strain in hot and humid weather

Science Daily - Heart Disease

New collaborative research has shown that using a fan in hot and humid weather reduces cardiac strain in older people, contradicting recommendations from the Centers of Disease Control and Prevention in the US. The study looked at the efficacy of different low-cost cooling strategies -- such as electric fans with and without spraying water on the skin -- for older adults, who are known to be at a heightened health risk during hot summer weather.

Research 112
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Empowering hearts: advancing cardiovascular research for women’s health

The British Journal of Cardiology

Cardiovascular disease remains the leading cause of death for women, responsible for over a third of all deaths. 1 In contrast, women remain widely under-represented in cardiovascular trials, 2 as well as in their roles as physicians and trialists. 3 The scarcity of female representation in cardiology carries broad consequences, affecting patient care quality, workplace diversity, and the inclusion of women in clinical trials.

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Five minutes of extra exercise a day could lower blood pressure

Science Daily - Heart Disease

New research suggests that adding a small amount of physical activity -- such as uphill walking or stair-climbing -- into your day may help to lower blood pressure.

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Early-Life Sugar Restriction Reduced Diabetes, Hypertension Risk

Med Page Today

(MedPage Today) -- SAN ANTONIO -- Limiting exposure to sugar starting in utero reduced risk and delayed onset of type 2 diabetes and hypertension in adulthood, a study showed. Adults exposed to early-life sugar rationing in the U.K. for at least.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Epigenomic biomarkers of cardiometabolic disease: How far are we from daily practice?

Cardiovascular Diabetology

Determining whether someone has cardiometabolic disease (CMD), especially in the early stages, can be complicated. Risk stratification ordinarily depends on an extended process relying on medical history that.

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Monica Kraft, MD: Discussing Phase 3b Findings on Albuterol/Budesonide for Asthma

HCPLive

This interview with Kraft features a discussion regarding her team’s new data from the BATURA study on albuterol for patients’ asthma exacerbations.

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Phase 3 Data Shows TEV-‘749 Injection Improves Social Function in Schizophrenia

HCPLive

Teva presents 2 findings at Psych Congress 2024: TEV’749’s effects on social function and quality of life in adults with schizophrenia and risperidone adherence patterns.

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Study shows how high blood sugar increases risk of thrombosis

Medical Xpress - Cardiology

A study conducted at the Center for Research on Redox Processes in Biomedicine (Redoxoma) helps understand how high blood sugar (hyperglycemia), one of the manifestations of diabetes, can cause thrombosis. The findings, reported in an article published in the Journal of Thrombosis and Haemostasis, can contribute to the development of strategies to prevent cardiovascular dysfunction in diabetics.

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Atorvastatin vs. Rosuvastatin: Do Effectiveness and Safety Differ?

NEJM Journal Watch - Cardiology

In this observational study, rosuvastatin was associated with lower 6-year mortality but interpreting and applying the results is not straightforward.

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Study reveals how cancer immunotherapy may cause myocarditis in some patients

Medical Xpress - Cardiology

Some patients being treated with immune checkpoint inhibitors, a type of cancer immunotherapy, develop a dangerous form of heart inflammation called myocarditis.

Cancer 81
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Work-Related Stress Linked to Poor Cardiovascular Health in US Adults

HCPLive

Work-related stress associated with adverse cardiovascular health in diverse US adult population, indicating potential risk factor for CVD prevention.

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Data suggest work-related stress compromises cardiovascular health

Medical Xpress - Cardiology

In a large multi-ethnic group of adults in the United States without cardiovascular disease, those with work-related stress were more likely to have unfavorable measures of cardiovascular health. The findings are published in the Journal of the American Heart Association.

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FDA Accepts BLA for Denosumab Biosimilar

HCPLive

If approved, HLX14 would follow the first 2 denosumab biosimilar approvals in March 2024.

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Secondary MR and Percutaneous Interventions: Key Points

American College of Cardiology

The following are key points to remember from a state-of-the-art review on treatment options for patients with secondary mitral regurgitation (SMR).

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Mazen Noureddin, MD: Differences in Resmetirom Efficacy Based on Body Weight, BMI

HCPLive

Noureddin explains the efficacy of resmetirom doses and how they vary based on patients’ body weight and BMI, supporting current prescribing practices.

BMI 64
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Left atrial strain in patients without cardiovascular disease: uncovering influencing and related factors

Cardiovascular Ultrasound

Despite its proven prognostic value in different contexts, the precise implications of left atrial strain (LAS) assessment throughout different phases of the atrial cycle remain uncertain. A direct correlation.

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Filgotinib Continues to Show Efficacy for RA in LTE Studies

HCPLive

Week 156 efficacy and safety data from the FINCH 4 study are consistent with that seen in FINCH 1, 2, and 3.

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Pre-Hospital Randomized Trial of Medication Route in Out-of-Hospital Cardiac Arrest

American College of Cardiology

The goal of the PARAMEDIC-3 trial was to compare the efficacy and safety of an initial vascular access strategy of intraosseous (IO) versus peripheral intravenous (IV) access for medication administration in out-of-hospital cardiac arrest.

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Allergy Month in Review | October 2024

HCPLive

In this review of the month of October, some of the most notable advancements and news in the field of allergy were highlighted.

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TAVR in Younger Patients; Atorvastatin vs. Rosuvastatin; Sedentary Behavior and Blood Pressure

American College of Cardiology

In this week’s View, Dr. Eagle looks at the outcomes of balloon-expandable transcatheter aortic valve replacement (TAVR) in younger patients.

TAVR 53
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H-NMR metabolomics identifies three distinct metabolic profiles differentially associated with cardiometabolic risk in patients with obesity in the Di@bet.es cohort

Cardiovascular Diabetology

Obesity is a complex, diverse and multifactorial disease that has become a major public health concern in the last decades. The current classification systems relies on anthropometric measurements, such as BMI.

Obesity 52
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American Heart Association to honor 8 cardiology leaders

Becker's Hospital Review - Cardiology

The American Heart Association will recognize eight leaders in cardiology at the organization's annual Scientific Sessions conference, set for Nov. 16-18.

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Changes in the estimated glucose disposal rate and incident cardiovascular disease: two large prospective cohorts in Europe and Asia

Cardiovascular Diabetology

Previous study found that estimated glucose disposal rate (eGDR) was significantly associated with cardiovascular disease (CVD). However, little is known about the change in eGDR over time and its association.

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How breast cancer screening can identify CVD risk

Becker's Hospital Review - Cardiology

Breast arterial calcifications are benign calcium buildups that in mammograms look like white parallel lines. Measuring these calcifications may improve cardiovascular risk in women, according to a study published Sept. 27 in JACC: Advances.

Cancer 52
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ZIP7 contributes to the pathogenesis of diabetic cardiomyopathy by suppressing mitophagy in mouse hearts

Cardiovascular Diabetology

Although the exact role of mitophagy in the pathogenesis of diabetic cardiomyopathy (DCM) caused by type 2 diabetes mellitus (T2DM) remains controversial, recent studies revealed inhibition of mitophagy exacer.

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Nephrology Month in Review: October 2024

HCPLive

This nephrology month in review spotlights HCPLive’s coverage of ASN Kidney Week, the debut of a new podcast, and new research on IgA nephropathy.

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Outcomes of Intravascular Lithotripsy-Assisted Transfemoral TAVR

American College of Cardiology

What are the contemporary characteristics, trends, and outcomes of intravascular lithotripsy (IVL)-assisted transfemoral (TF) transcatheter aortic valve replacement (TAVR) in the United States?

TAVR 45
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Phase 3 Data Shows Lumateperone Delays Schizophrenia Relapse Longer Than Placebo

HCPLive

Phase 3 data shows lumateperone 42 mg significantly delayed relapse in patients with schizophrenia vs placebo, with 63% reduced relapse risk and good tolerance.

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Intravenous vs. Intraosseous Vascular Access During Out-of-Hospital Cardiac Arrest

American College of Cardiology

The goal of the IVIO trial was to compare the efficacy and safety of an initial vascular access strategy of intraosseous (IO) versus peripheral intravenous (IV) access for medication administration in nontraumatic out-of-hospital cardiac arrest.

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Evolutionary Characteristics in Primary Aldosteronism Patients

Hypertension Journal

Hypertension, Volume 82, Issue 1 , Page 96-105, January 1, 2025. BACKGROUND:Primary aldosteronism is predominantly caused by excessive aldosterone production from the adrenal cortex, and the aldosterone-producing structures could take many forms, like adenomas, nodules, micronodules, and so on. Most studies of primary aldosteronism were limited to the hotspot driver genes responsible for autonomous aldosterone production; however, the panoramic genetic architecture and genomic alterations of ald

Cancer 40
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Significance of the local largest bipolar voltage for the optimized ablation strategy using very high‐power short duration mode

Journal of Cardiovascular Electrophysiology

Characteristics of acute insufficient lesions during vHPSD ablation were analyzed in the retrospective phase. Based on these data, an optimized approach combining both vHPSD ablation and AI-guided ablation was prospectively tested, resulting in an approximately 90% first-pass PVI rate. Abstract Purpose Very high-power short-duration (vHPSD) ablation creates shallower lesions, potentially reducing efficacy.

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Rhythmic Contractions of Lymph Vessels and Lymph Flow Are Disrupted in Hypertensive Rats

Hypertension Journal

Hypertension, Volume 82, Issue 1 , Page 72-83, January 1, 2025. BACKGROUND:Hypertension increases the risk of lymphedema in patients with comorbidities, but whether hypertension directly compromises lymph vessel (LV) function and lymph flow is unclear. We compared the contractions of mesenteric LVs ex vivo and lymph flow in vivo between normotensive and Ang II (angiotensin II)-induced hypertensive rats and explored the ionic basis of contractile patterns.

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Prognosis of patients with wild‐type transthyretin cardiac amyloidosis and non‐sustained ventricular tachycardia

Journal of Cardiovascular Electrophysiology

Central Figure. Patients with ATTRwt cardiac amyloidosis have a high prevalence of NSVT during clinically indicated Holter monitoring. Patients with NSVT have a higher risk of incident sustained VT compared to those without NSVT. Abbreviations: ATTRwt = Amyloid transthyretin wild-type, NSVT = nonsustained ventricular tachycardia, VA = ventricular arrhythmia, VE = ventricular ectopy Abstract Introduction Little is known regarding the prevalence and prognostic implications of non-sustained ventric

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Woman with Marfan syndrome had an emergency C-section and heart surgery the same day

Medical Xpress - Cardiology

The moment Kirsten Dorsey realized she would deliver her second child and have open-heart surgery on the same day, her heart raced and her breath quickened.

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Management Strategies to Prevent Stroke in Patients with Atrial Fibrillation and Malignant Left Atrial Appendage

HeartRhythm

Patients with atrial fibrillation (AF) and malignant left atrial appendage (LAA) may benefit from LAA closure (LAAC); however, evidence is limited.

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Tricuspid transcatheter edge-to-edge repair explored in severe tricuspid regurgitation

Medical Xpress - Cardiology

For patients with symptomatic and severe tricuspid regurgitation (TR), tricuspid transcatheter edge-to-edge repair (T-TEER) yields significant improvements in primary end points, according to a study published online Oct. 27 in the Journal of the American College of Cardiology to coincide with the annual Transcatheter Cardiovascular Therapeutics conference, held from Oct. 27 to 30 in Washington, D.C.