Thu.Oct 12, 2023

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What clinical scenario fits best?

Dr. Smith's ECG Blog

B elow are 4 ECGs from the same patient. Accompanying the ECGs is some clinical information. Look at the ECGs and consider the timeline and other information. At the bottom will be five alternative clinical scenarios to explain the findings. Which one do you think fits better with the ECGs and their timeline? The patient is a 60 something female. She was admitted to the hospital with clinical signs of infection.

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Antagonism of contractile forces in left ventricular hypertrophy: a diagnostic challenge for better pathophysiological and clinical understanding

Open Heart

Cardiac function is characterised by haemodynamic parameters in the clinical scenario. Due to recent development in imaging techniques, the clinicians focus on the quantitative assessment of left ventricular size, shape and motion patterns mostly analysed by echocardiography and cardiac magnetic resonance. Because of the physiologically known antagonistic structure and function of the heart muscle, the effective performance of the heart remains hidden behind haemodynamic parameters.

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Preclinical Study on a Novel Fluoroderivative of Dabigatran Etexilate in Animal Models

Journal of Cardiovascular Pharmacology

Here, the fluorinated derivative, R1, was synthesized from the fluorinated dabigatran derivative (R0). The in vivo pharmacokinetic characteristics of orally administered R1, R0 injection, and dabigatran etexilate in rats were compared. Safety evaluation results showed no significant changes in the QRS wave or PR and QT intervals in rat lead II electrocardiograms.

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Maternal mental health: a key area for future research among women with congenital heart disease

Open Heart

In this viewpoint, we respond to the recently published national priorities for research in congenital heart disease (CHD) among adults, established through the James Lind Alliance Priority Setting Partnership, with specific attention to priority 3 (mental health) and priority 5 (maternal health). Our recent policy impact project explored how maternal mental health is currently addressed in adult congenital heart disease (ACHD) services in the National Health Service, identified gaps and discuss

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Modifying Dietary Sodium and Potassium Intake: An End to the Salt Wars?: Salt Series

Hypertension Journal

Hypertension, Ahead of Print. Excessive salt intake raises blood pressure, but the implications of this observation for human health have remained contentious. It has also been recognized for many years that potassium intake may mitigate the effects of salt intake on blood pressure and possibly on outcomes such as stroke. Recent large randomized intervention trials have provided strong support for the benefits of replacing salt (NaCl) with salt substitute (75% NaCl, 25% KCl) on hard outcomes, in

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Deep learning for automated left ventricular outflow tract diameter measurements in 2D echocardiography

Cardiovascular Ultrasound

Measurement of the left ventricular outflow tract diameter (LVOTd) in echocardiography is a common source of error when used to calculate the stroke volume. The aim of this study is to assess whether a deep le.

Stroke 40
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Unveiling Bacterial Autophagosomes in Human Intracranial Aneurysm Wall Tissue: A Rare Insight

Stroke Journal

Stroke, Volume 54, Issue 12 , Page e498-e499, December 1, 2023.

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Iatrogenic Left Atrial Dissection After a Percutaneous Coronary Revascularization: Challenges and Management Strategies

Circulation: Cardiovascular Imaging

Circulation: Cardiovascular Imaging, Ahead of Print.