Dr. Malcolm Kendrick

DECEMBER 10, 2023

10th December 2023 A very important study – please watch Very high low density lipoprotein levels with no impact on plaque progression I interrupt my series on what is wrong with the health service to bring you breaking news. I was sent the e-mail below, directing me to a short YouTube presentation by Dr Shawn Baker. It highlights a study which provides very strong evidence that a very high LDL (as seen in some people who go on a keto diet), has no impact on coronary artery plaque progression.

Plaque 145

Plaque Cholesterol Diet Hypertension 145

HCPLive

DECEMBER 10, 2023

Study results presented at the 2023 American Society of Hematology Annual Meeting and Exposition found equal immune tolerance induction success rates regardless of race/ethnicity.

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ECG Weekly Workout

DECEMBER 10, 2023

This content is for members only

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96

HCPLive

DECEMBER 10, 2023

The revised algorithm demonstrates 97% sensitivity in identifying pregnant patients with inherited bleeding disorders.

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Heart Sisters

DECEMBER 10, 2023

With apologies to Dr. Seuss, I offer my own poetic interpretation of what getting misdiagnosed in mid-heart attack can feel like for far too many women.

Heart Attack 91

Heart Attack Heart attacks 91

Medical Xpress - Cardiology

DECEMBER 10, 2023

Mechanical thrombectomy (MT) is safe and effective in real-world, high-risk patients with pulmonary embolism (PE), according to a study published online Oct. 31 in the Journal of the Society for Cardiovascular Angiography & Interventions.

Embolism 87

Embolism Pulmonary 87

HCPLive

DECEMBER 10, 2023

Although more than half of female patients with sickle cell disease reported sickle cell pain associated with their menstrual cycles, only 12.5% had used ≥1 hormonal therapies within the past 3 months.

Sickle Cell Disease 80

Sickle Cell Disease 80

HCPLive

DECEMBER 10, 2023

New case-control data from ASH 2023 show a particularly increased link between sickle cell trait and monocytic and myeloid leukemia progression.

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ECG Guru

DECEMBER 10, 2023

Atrial flutter and atrial fibrillation are 2 different cardiac arrhythmias, but occur frequently side by side in the same patient. Here is an example of how atrial flutter degenerataes into atrial fibrillation. The initially ordered atrial activity (left in the picture) with 2 flutter waves/1 QRS complex changes into irregular atrial activity (right in the picture) and the RR intervals become completely irregular.

Atrial Flutter 52

Atrial Flutter Atrial Fibrillation Arrhythmia 52

HCPLive

DECEMBER 10, 2023

These findings presented at ASH show promise for future studies on GBT02601 as a potential alternative to voxelotor for sickle cell disease.

Sickle Cell Disease 52

Sickle Cell Disease 52

ECG Guru

DECEMBER 10, 2023

Why is this a high-grade AV block? If at least 3 P-waves are not conduced and there is nominal AV conduction before and after, this can be considered a higher-grade AV block. in this Holter strip, P1, P2 and all P-waves from P6 onwards are conduced, albeit with a prolonged PR interval (first-grade AV block). P3, P4, P5 are not conducted. A junctional escape beat is seen before P5.

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HCPLive

DECEMBER 10, 2023

Extension analysis from a phase 1 trial show the investigative oral mitapivat was not associated with any discontinuations nor deaths over 2 years.

Sickle Cell Disease 52

Sickle Cell Disease 52

Circulation

DECEMBER 10, 2023

Circulation, Volume 148, Issue 24 , Page e281-e281, December 12, 2023.

Chest Pain 49

Chest Pain Circulation 49

Coronary Artery Disease Journal

DECEMBER 10, 2023

Background Cardiac 15O-water PET is a noninvasive method to evaluate epicardial and microvascular dysfunction and further quantitate absolute myocardial blood flow (MBF). Aim: The aim of this study was to assess the impact of revascularization on MBF and myocardial flow reserve (MFR) assessed with 15O-water PET and invasive flow and pressure measurements.

Angina 40

Angina Research 40

Circulation

DECEMBER 10, 2023

Circulation, Volume 148, Issue 24 , Page 1980-1981, December 12, 2023.

Article 49

Article Cardiomyopathy Circulation 49

Journal of Cardiovascular Electrophysiology

DECEMBER 10, 2023

The activation signal, or signature, defined as the cumulative number of recording sites that have activated per millisecond, was utilized to segment each re-entrant ventricular tachycardia (VT) circuit into inner and outer circuit pathways, and as an estimate of best ablation lesion location to prevent VT. Abstract Introduction Development of a rapid means to verify the ventricular tachycardia (VT) isthmus location from heart surface electrogram recordings would be a helpful tool for the electr

Tachycardia 40

Tachycardia Myocardial Infarction Ablation Article 40

Circulation

DECEMBER 10, 2023

Circulation, Volume 148, Issue 24 , Page 1979-1979, December 12, 2023.

Article 49

Article Cardiomyopathy Circulation 49

Journal of Cardiovascular Electrophysiology

DECEMBER 10, 2023

Abstract Introduction Transvenous lead extraction (TLE), while mostly a safe procedure, has risk of serious periprocedural complications. As such, overnight hospitalization remains a routine practice. In our center, we routinely discharge patients on the same day following an uncomplicated TLE. Methods This is a retrospective study of 265 consecutive patients who underwent uncomplicated TLE in our center between 2019 and 2021.

Hospital 40

Hospital Article 40

Circulation

DECEMBER 10, 2023

Circulation, Volume 148, Issue 24 , Page 1929-1931, December 12, 2023.

Peripheral Arterial Disease 45

Peripheral Arterial Disease Circulation 45

CardiacWire

DECEMBER 10, 2023

A new study in European Heart Journal – Digital Health showed that Us2.ai’s AI echo algorithm can interpret echocardiographic strain images with similar accuracy as conventional measurements, highlighting how AI can democratize cardiac strain exams and improve heart failure assessments. Echo strain imaging reflects myocardial deformation, and supports early heart failure diagnosis.

Heart Failure 59

Heart Failure Reimbursement CMS Outpatient 59

Circulation

DECEMBER 10, 2023

Circulation, Volume 148, Issue 24 , Page 1974-1975, December 12, 2023.

Circulation 45

Circulation 45

Circulation

DECEMBER 10, 2023

Circulation, Volume 148, Issue 24 , Page 1917-1918, December 12, 2023.

Circulation 45

Circulation 45

Circulation

DECEMBER 10, 2023

Circulation, Volume 148, Issue 24 , Page 1976-1978, December 12, 2023.

Heart Failure 45

Heart Failure Circulation 45