Mon.Sep 23, 2024

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NONSUSTAINED VT

ECG Guru

Extract from a Holter ECG, 2 continuous strips, recorded at 25 mm/s. At the top you can see a broad complex tachycardia without recognizable P waves, which ends spontaneously after 2 beats in the lower section. This is a VT. The very first beat in the 1st strip is most probably a fusion beat. After the end of the VT in the 2nd strip, a narrow QRS complex appears, here you can also recognize that atrial fibrillation is present.

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FDA Accepts NDA for Delgocitinib Cream Treatment of Chronic Hand Eczema

HCPLive

The FDA decision to accept the new drug application for delgocitinib cream is also occurring alongside the drug’s acceptance by the European Commission.

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ATRIAL FIBRILLATION

ECG Guru

Unfortunately, I can't remember who the author of this ECG is. Perhaps he/she will get in touch with me. However, the ECG is very nice (despite the less than optimal recording quality) and that's why I want to post it. I don't know the history. In the first section of the ECG we see coarse fibrillation waves and QRS complexes with very different RR intervals, which is why this is atrial fibrillation.

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New approach to defibrillation may improve cardiac arrest outcomes

Science Daily - Heart Disease

A new observational study suggests the position in which responders initially place the two defibrillator pads on the body may make a significant difference in returning spontaneous blood circulation after shock from a defibrillator.

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Precocious Puberty More Common in Children with Hidradenitis Suppurativa

HCPLive

A new case-control study reported a higher prevalence of precocious puberty in children and adolescents with HS compared with controls.

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TESLA Trial: Does Timing Make or Break Thrombectomy for Large-Core Strokes?

Med Page Today

(MedPage Today) -- The TESLA trial was unable to support a benefit to thrombectomy for stroke patients with large-core infarcts identified on noncontrast CT within 24 hours. Unlike other studies, endovascular therapy in TESLA conferred no significantly.

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Fecal Microbiota Transplant Delivery Method May Impact Benefit for Treatment of IBS

HCPLive

Subgroup analyses revealed FMT delivered through endoscopy, nasojejunal tube, and rectal enema had a greater impact on clinical response, symptom improvement, and quality of life.

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Quality of Life and Diagnostic Considerations for FCS

HCPLive

Panelists discuss how familial chylomicronemia syndrome (FCS) imposes a significant economic burden on patients, affecting their ability to stay employed and manage the costs associated with long-term care and treatment.

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Lipoprotein(a) and Cardiovascular Disease: Key Points

American College of Cardiology

The following are key points to remember from a review of lipoprotein(a) [Lp(a)] and cardiovascular disease (CVD):

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Familial Chylomicronemia Syndrome: Diagnosis, Genetic Factors, and Long-Term Health Implications

HCPLive

Panelists discuss how familial chylomicronemia syndrome (FCS) is characterized by severe hypertriglyceridemia and genetic mutations in the LPL gene, highlighting the key diagnostic criteria and complications, such as acute pancreatitis, while emphasizing the impact of untreated FCS on patient quality of life and long-term health risks.

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Minority stress, discrimination and cardiovascular health

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 24 September 2024; doi:10.1038/s41569-024-01083-1 John C. Lin and colleagues explore the history of racial disparities in cardiovascular outcomes and discuss the landmark findings of the CARDIA study and its contribution to the minority stress model.

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Utilizing Long-Term Atopic Dermatitis Data in Clinical Practice

HCPLive

Medical experts discuss long-term data for other systemic agents in atopic dermatitis and how this information informs their treatment decisions.

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Calcium channel blockers and beta blockers in pediatric supraventricular tachycardia

Journal of Cardiovascular Electrophysiology

Abstract Introduction Supraventricular tachycardia (SVT) is a common pediatric arrhythmia. Beta blockers (BBs) and calcium channel blockers (CCBs) are used for treatment despite little data examining their use. We describe the prescriptive tendencies, efficacy, and tolerability of BBs and CCBs used in the treatment of pediatric SVT. Methods and Results This is a multicenter retrospective cohort study from three academic children's hospitals.

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Data on Early Itch Relief with JAK Inhibitors in Atopic Dermatitis

HCPLive

Medical experts review and comment on the effectiveness of oral JAK inhibitors in providing itch relief for patients with atopic dermatitis.

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Feature | Knowledge is Power: Survey Shows Increased Awareness of HoFH

American College of Cardiology

Familial hypercholesterolemia (FH), characterized by lifelong elevations in low-density lipoprotein cholesterol (LDL-C), is the most common autosomal-dominant genetic disorder in the world. Without treatment, individuals with FH, compared with those without FH, are at 10- to 20-times higher risk of early coronary artery disease and subsequent premature death.

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MASLD Associated with Greater Risk of Serious Bacterial Infection Requiring Hospitalization

HCPLive

Meta-analysis findings suggest a significant association between MASLD and serious bacterial infection risk.

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Acute artery occlusion -- which one?

Dr. Smith's ECG Blog

Written by Willy Frick with edits by Ken Grauer A woman in her 70s with a history of hypertension presented with acute onset shortness of breath. She was out walking her dog when she developed sudden dizziness and light-headedness. When EMS found her, she was dyspneic and diaphoretic. Her ECG is shown below: What do you think? The conventional machine algorithm interpreted this ECG as STEMI.

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Acne and Rosacea Updates 2024, with James Del Rosso, DO

HCPLive

Del Rosso reviews several key highlights from his Maui Derm presentation on acne and rosacea updates from 2024.

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PCI for stable angina : Sham trials are welcome, but not OMT shaming trials !

Dr. S. Venkatesan MD

* Caution : Language -Harsh. Likelihood of truth : High The flamboyant genius of Andreas Roland Gruntzig, from Zurich gifted us the path-breaking treatment modality for coronary stenosis five decades ago. After a series of experiments in animals and peripheral vessels, he proved with a single patient N-1 study that effectively treated refractory LAD angina in a 38-year-old man in 1977.

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Vitamin D May Play Key Role in Anemia Prevention, Study Finds

HCPLive

New research establishes a strong causal link between elevated 25(OH)D levels and a reduced risk of anemia.

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Erectile Disfunction as an ASCVD Risk-Enhancing Factor: Highlights From the Princeton IV Consensus Guidelines

American College of Cardiology

Commentary based on Kloner RA, Burnett AL, Miner M, et al. Princeton IV consensus guidelines: PDE5 inhibitors and cardiac health. J Sex Med 2024;21:90-116.

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Bimekizumab Approved for Psoriatic Arthritis, Ankylosing Spondylitis, AxSpA

HCPLive

BIMZELX was previously approved for treating moderate-to-severe plaque psoriasis.

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The Role of Virology in Rheumatic Disease With Leonard Calabrese, DO

HCPLive

Calabrese discussed the multi-faceted role of viral infections in the field of rheumatology ahead of the 2024 CCR West meeting.

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