Fri.Aug 30, 2024

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Wegovy Protects Against Deadly COVID Cases

Med Page Today

(MedPage Today) -- LONDON -- The clinical benefits of semaglutide (Wegovy) went beyond expectations in the SELECT trial, given the reductions in non-cardiovascular and infectious disease deaths observed. Among people with overweight or obesity.

Obesity 143
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Physiology Friday #233: Exercise Makes Us More Stress-Resilient: Now We Know Why

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. Thanks to the premium sponsor of this newsletter: FSTFUEL electrolyte supplement. FSTFUEL combines electrolytes with amino acids to help your body maintain hydration and optimal functioning during exercise or intermittent fasting, so you don't have to choose between fasting and fitness. It’s a zero-sugar electrolyte drink that tastes awesome.

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Is long-term beta-blocker therapy needed after a heart attack?

Science Daily - Heart Disease

The appropriate duration of beta-blocker treatment after a heart attack (a myocardial infarction [MI]) is unknown in patients who do not need to take beta-blockers for another reason. In the ABYSS trial, the cardiovascular safety of interrupting beta-blocker could not be shown in comparison with beta-blocker continuation and beta-blocker interruption did not improve quality of life.

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Five Things Every Middle Aged Adult Should Know About Sleep & Heart Disease.

Dr. Paddy Barrett

Most people do not know that sleep is a key factor when it comes to good cardiovascular health. Because of this, sleep is pushed to the bottom of the list of priorities for addressing cardiovascular health. In my view, this is a terrible idea. Here is why. Get Sleep Right. Get Everything Else Right. There is a multitude of factors that will determine your cardiovascular risk.

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Amyloidosis Drug Improves Outcomes, Survival

Med Page Today

(MedPage Today) -- LONDON -- Vutrisiran (Amvuttra) improved functional and disease outcomes as well as survival in transthyretin amyloidosis cardiomyopathy (ATTR-CM), according to findings from the HELIOS-B phase III trial. And the benefits.

Outcomes 105
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Clinical Measures Insufficient for Capturing Full Patient Experience for Psoriasis

HCPLive

These data suggest that there are a subset of individuals with complete skin clearance of their psoriasis who report residual effects of their condition.

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Stopping Beta-Blockers Did Not Go as Planned for Long-Time Users

Med Page Today

(MedPage Today) -- LONDON -- Heart attack survivors who were expected to be fine after going off their beta-blockers fared worse clinically compared with those who continued them, a randomized trial showed. After years of taking these relatively.

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Inflammation, Cholesterol, Lipoprotein(a), and 30-Year Cardiovascular Outcomes in Women

The New England Journal of Medicine

Measurement of low-density lipoprotein cholesterol, high-sensitivity C-reactive protein, and lipoprotein(a) predicted the 30-year cardiovascular disease risk among women enrolled in the Women’s Health Study.

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Catching Up on Sleep on Weekends Links to 20% Lower Risk of Developing Heart Disease

HCPLive

People with the most weekend catch-up sleep had a 20% lower risk of heart disease, especially those who were sleep-deprived during the week.

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Prevention of Cardiovascular Disease — Don’t Stop Thinking about Tomorrow

The New England Journal of Medicine

Taking a long-term view of cardiovascular disease prevention is an attractive strategy since atherosclerosis begins early in life and progresses over decades. Lowering low-density lipoprotein (LDL) cholesterol levels and improving lifestyle habits are mainstay strategies for reducing the risk of cardiovascular disease.1 Moreover, emerging therapeutic targets include vascular.

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New Research Identifies Genes Associated With Gout RIsk

HCPLive

Researchers identified 2 genes associated with increased risk and 3 associated with decreased risk.

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New procedure puts Lee Health on cutting edge of cardiac care

Becker's Hospital Review - Cardiology

Fort Myers, Fla.-based Lee Health completed its first fully endoscopic heart-valve surgery through the smallest incision possible — putting it on the forefront of cardiac care, it said in an Aug. 29 news release.

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Comparative effects of glucagon-like peptide-1 receptor agonists and sodium-glucose co-transporter-2 inhibitors on heart failure with preserved ejection fraction in diabetic patients: a meta-analysis

Cardiovascular Diabetology

Heart failure with preserved ejection fraction (HFpEF) is common in type 2 diabetes mellitus (T2D), leading to high morbidity and mortality. Managing HFpEF in diabetic patients is challenging with limited trea.

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In Women, History of Cancer Linked to Subclinical Atherosclerosis

HCPLive

Sara Diaz Savaria, MD, discusses a study from ESC Congress 2024 examining the utility of cancer history in women as a predictor of subclinical atherosclerosis.

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STS Boot Camp: Refine Skills Through Hands-on Practice

Society of Thoracic Surgeons - Early Career

During the 2024 STS Boot Camp in Chicago, 60 first-year cardiothoracic CT surgery residents learned from leading CT surgeons from across the country, who provided expert instruction as they gained practical experience by simulating real-world cases and emergency scenarios.

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The association between index-year, average, and variability of the triglyceride-glucose index with health outcomes: more than a decade of follow-up in Tehran lipid and glucose study

Cardiovascular Diabetology

The association between baseline triglyceride glucose index (TyG index) and incident non-communicable diseases, mainly in Asian populations, has been reported. In the current study, we aimed to evaluate the as.

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Overcoming Status Quo Bias: Embracing Evidence-Based Guidelines in Cardiometabolic Care 

Cardiometabolic Health Congress

Cardiometabolic diseases, encompassing cardiovascular conditions and metabolic disorders like diabetes, are among the most widespread global health challenges. These conditions often intersect, sharing common risk factors and underlying mechanisms. Effectively addressing them requires comprehensive, evidenced based cardiometabolic care that integrates the latest research into clinical practice.

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Two-week continuous glucose monitoring-derived metrics and degree of hepatic steatosis: a cross-sectional study among Chinese middle-aged and elderly participants

Cardiovascular Diabetology

Continuous glucose monitoring (CGM) devices provide detailed information on daily glucose control and glycemic variability. Yet limited population-based studies have explored the association between CGM metric.

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Creating the Perfect Cardio Workout for Your Heart

AMS Cardiology

Regular cardio exercise is one of the best ways to keep your heart strong and healthy; it helps improve blood flow and boosts your energy levels. But with so much information out there, it can be overwhelming to know where to start. Below our experts will walk you through creating a cardio workout that’s right for you, especially if you’re concerned about your heart health.

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Rehospitalisation risk by hypnotics class in older patients with heart failure: a cohort study utilizing administrative claims data in Japan

Open Heart

Background Studies comparing the safety of orexin receptor antagonists and other hypnotic types for older patients with heart failure (HF) remain lacking. This study aimed to compare orexin receptor antagonists (suvorexant) with benzodiazepines or Z-drugs for sleep treatment and investigate the risk of acute HF-related rehospitalisation in older patients with HF.

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Stopping Beta-Blockers Did Not Go as Planned for Long-Time Users

Med Page Today

(MedPage Today) -- LONDON -- Heart attack survivors who were expected to be fine after going off their beta-blockers fared worse clinically compared with those who continued them, a randomized trial showed. After years of taking these relatively.

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Nurturing Your Heart: Yoga, Meditation, and Stress-Busting Techniques for Cardiovascular Wellness

MIBHS

In our fast-paced world, stress has become an unwelcome companion, silently taking a toll on our heart health. Fortunately, ancient practices like yoga and meditation, along with other stress-reduction techniques, offer powerful tools to combat stress and nurture our cardiovascular system. This blog explores how these practices can significantly contribute to heart health and overall well-being.

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STOP-or-NOT: No Benefit to Discontinuing RASi Prior to Major Surgery

HCPLive

The STOP-or-NOT trial found similar outcomes for continuation or discontinuation of RAS inhibitors before noncardiac surgery, supporting individualized decision-making.

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Stop-or-Not: Continuation vs. Discontinuation of RASIs Prior to Major Noncardiac Surgery

American College of Cardiology

A continuation strategy of renin-angiotensin system inhibitors (RASIs) before major noncardiac surgery was associated with better post-operative outcomes than discontinuation, based on results from the Stop-or-Not trial.

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Vutrisiran Reduces Cardiovascular Risk, Improves Quality of Life in ATTR-CM

HCPLive

HELIOS-B trial shows vutrisiran reduces all-cause mortality and CV events in ATTR-CM, with benefits consistent regardless of tafamidis use.

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Impaired glucose metabolism and the risk of vascular events and mortality after ischemic stroke: A systematic review and meta-analysis

Cardiovascular Diabetology

Diabetes mellitus (DM), prediabetes, and insulin resistance are highly prevalent in patients with ischemic stroke (IS).

Strokes 59
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ABYSS Trial: No Difference in Outcomes Continuing or Stopping Beta-Blockers Following MI

HCPLive

The ABYSS trial suggests no clear benefit of continuing beta-blockers post-MI in patients with preserved LVEF, echoing REDUCE-AMI findings.

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Assessment of Beta-Blocker Interruption 1 Year After an Uncomplicated Myocardial Infarction on Safety and Symptomatic Cardiac Events Requiring Hospitalization

American College of Cardiology

The goal of the ABYSS trial was to evaluate beta-blocker interruption compared with beta-blocker continuation after an uncomplicated myocardial infarction (MI).

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Gout Impacts Employment, Mitigated by Effective Management

HCPLive

Investigators identified 6 themes during semistructed interviews that contributed to and described the experience of people with gout.

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Impact of Renin-Angiotensin System Inhibitors Continuation on Outcome After Major Surgery

American College of Cardiology

The goal of the Stop-or-Not trial was to evaluate discontinuation of renin-angiotensin system inhibitors compared with continuation before major noncardiac surgery.

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Study Highlights Role of IL-33 in Link Between Asthma, Alopecia Areata

HCPLive

These Mendelian analysis results highlight an association between alopecia areata and asthma, indicating a mediating role of IL-33.

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A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

American College of Cardiology

The goal of the HELIOS-B trial was to evaluate vutrisiran compared with placebo among patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM).

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Common Pitfalls to Avoid When Interpreting Clinical Trials, with Deepak Bhatt, MD, MPH, MBA

HCPLive

Deepak Bhatt, MD, MPH, MBA, discusses common pitfalls for clinicians when interpreting trial data based on a presentation he led at ESC Congress 2024.

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c-Src Is Responsible for Mitochondria-Mediated Arrhythmic Risk in Ischemic Cardiomyopathy

Circulation: Arrhythmia and Electrophysiology

Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:Increased mitochondrial Ca2+uptake has been implicated in the QT prolongation and lethal arrhythmias associated with nonischemic cardiomyopathy. We attempted to define the role of mitochondria in ischemic arrhythmic risk and to identify upstream regulators.METHODS:Myocardial infarction (MI) was induced in wild-type FVB/NJ mice by ligation of the left anterior descending coronary artery.

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Practical Tools for the Administration of Intravenous Iron

HCPLive

Experts on iron deficiency anemia discuss practical tools they utilize for the clinical administration of intravenous iron.

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Heart of Health Policy | How to Make Legislative Conference Talking Points Your Own

American College of Cardiology

The 2024 Legislative Conference taking place Sept. 29 to Oct. 1 in Washington, DC, presents a unique opportunity for ACC members to learn more about health policy, network with colleagues and speak directly with lawmakers on Capitol Hill about some of the most pressing issues facing clinicians, patients and the profession.

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How to Manage Infusion Reactions with Intravenous Iron

HCPLive

Steven Fein, MD, MPH, shares insights on the management of infusion reactions seen in patients receiving intravenous iron.

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