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Research Highlights: When adults became angry after remembering past experiences, the function of cells lining the blood vessels was negatively impaired, which may restrict blood flow. Previous research has found that this may increase the risk of.
A simple blood test could allow doctors to determine whether a person may be at higher risk for stroke or cognitive decline during their lifetime, according to a new study.
DALLAS, May 1, 2024 – Each year, approximately 800,000 people in the U.S. have a stroke.[1] Six local stroke heroes from across the country are being recognized by the American Stroke Association, a division of the American Heart Association, for.
Bacterial translocation from the gut microbiota is a source of sepsis in susceptible patients. Previous work suggests that overgrowth of gut pathobionts, including Klebsiella pneumoniae, increases the risk of disseminated infection. Our data from a human dietary intervention study found that, in the absence of fiber, K. pneumoniae bloomed during microbiota recovery from antibiotic treatment.
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Researchers have found that cells inside clogged arteries have cancer-like properties that aggravate atherosclerosis, and anticancer drugs could be a new treatment.
When adults became angry after remembering past experiences, the function of cells lining the blood vessels was negatively impaired, which may restrict blood flow, according to a new study. Previous research has found that this may increase the risk of heart disease and stroke. In this study, episodes of anxiety and sadness did not trigger the same change in functioning of the blood vessel lining.
When adults became angry after remembering past experiences, the function of cells lining the blood vessels was negatively impaired, which may restrict blood flow, according to a new study. Previous research has found that this may increase the risk of heart disease and stroke. In this study, episodes of anxiety and sadness did not trigger the same change in functioning of the blood vessel lining.
Dr Nils Lehnen, Senior Physician at the Clinic for Diagnostic and Interventional Neuroradiology and Paediatric Neuroradiology at the UKB. Image courtesy of University Hospital Bonn (UKB) / R. Müller milla1cf Wed, 05/01/2024 - 12:07 May 1, 2024 — In an ischemic stroke, an artery in the brain is blocked by blood clots and the brain cells can no longer be supplied with blood as a result.
Pain and inflammation are biologically intertwined responses that warn the body of potential danger. In this issue of the JCI, Defaye, Bradaia, and colleagues identified a functional link between inflammation and pain, demonstrating that inflammation-induced activation of stimulator of IFN genes (STING) in dorsal root ganglia nociceptors reduced pain-like behaviors in a rodent model of inflammatory pain.
The Society for Cardiovascular Angiography & Interventions (SCAI) kicks off its SCAI Scientific Sessions 2024 this week, May 2-4 in Long Beach, CA, bringing together more than 1,800 clinicians, scientists, researchers, and innovators in the field of interventional cardiology and endovascular medicine. Image courtesy: Long Beach Convention Center christine.book Wed, 05/01/2024 - 14:51 May 1, 2024 — The annual Society for Cardiovascular Angiography & Interventions ( SCAI ) kicks off its SCAI Scien
Despite ChatGPT's reported ability to pass medical exams, new research indicates it would be unwise to rely on it for some health assessments, such as whether a patient with chest pain needs to be hospitalized.
The gut microbiota is an integral part of the human metaorganism that is required to shape physiologic host immune responses including host defense against pathogens. Disease-associated gut dysbiosis has been characterized by blooms of pathobionts, which are bacterial species that can drive disease under certain conditions. Pathobionts like Enterobacteriaceae often bloom during flares of inflammatory bowel disease (IBD) and are causally linked with IBD in murine models.
Nature Reviews Cardiology, Published online: 02 May 2024; doi:10.1038/s41569-024-01024-y Physiological responses to stress are thought to increase the risk of cardiovascular disease via haemodynamic, vascular and immune perturbations. In this Review, Vaccarino and Bremner focus on issues with the measurement of psychological stress and the underlying pathobiology connecting stress to the risk of cardiovascular disease.
Urinary cytokines GDF-15, IL-6, and EGF significantly strengthened the predictability of IgAN prognosis and may be viable biomarker candidates for disease progression.
A simple blood test could allow doctors to determine whether a person may be at higher risk for stroke or cognitive decline during their lifetime, according to a new UCLA Health study.
The appearance of senescent cells in age-related diseases has spurred the search for compounds that can target senescent cells in tissues, termed senolytics. However, a major caveat with current senolytic screens is the use of cell lines as targets where senescence is induced in vitro, which does not necessarily reflect the identity and function of pathogenic senescent cells in vivo.
Artificial intelligence experts at Cedars-Sinai and the Smidt Heart Institute created a dataset with more than 1 million echocardiograms, or cardiac ultrasound videos, and their corresponding clinical interpretations. Using this database, they created EchoCLIP, a powerful machine learning algorithm that can "interpret" echocardiogram images and assess key findings.
Epigenetic regulatory mechanisms are underappreciated, yet are critical for enteric nervous system (ENS) development and maintenance. We discovered that fetal loss of the epigenetic regulator Bap1 in the ENS lineage caused severe postnatal bowel dysfunction and early death in Tyrosinase-Cre Bap1fl/fl mice. Bap1-depleted ENS appeared normal in neonates; however, by P15, Bap1-deficient enteric neurons were largely absent from the small and large intestine of Tyrosinase-Cre Bap1fl/fl mice.
The following are key points to remember from a review comparing the US and European guidelines for normal-flow low-gradient (NFLG) aortic stenosis (AS).
In lung, thromboxane A2 (TXA2) activates the TP receptor to induce proinflammatory and bronchoconstrictor effects. Thus, TP receptor antagonists and TXA2 synthase inhibitors have been tested as potential asthma therapeutics in humans. Th9 cells play key roles in asthma and regulate the lung immune response to allergens. Herein, we found that TXA2 reduces Th9 cell differentiation during allergic lung inflammation.
Among Hispanic women living in the U.S., 37% are affected by cardiovascular disease and it is the primary cause of death, according to a JACC Review Topic of the Week published April 22.
DALLAS, May 1, 2024 – Every 40 seconds someone in the U.S. has a stroke[1], and 1 in 4 stroke survivors will have another one[2]. During May - American Stroke Month -, the American Stroke Association, a division of the American Heart Association, is.
Every 40 seconds someone in the U.S. has a stroke and 1 in 4 stroke survivors will have another one. During May, American Stroke Month, the American Stroke Association, a division of the American Heart Association, is raising awareness nationwide that stroke is largely preventable, treatable and beatable.
In the final results of a randomized trial involving patients with HIV infection, pitavastatin reduced the incidence of adverse cardiovascular events at 5.6 years of follow-up as compared with placebo.
An observational study out of Emory suggests that aspirin could be the preventative Lp(a) treatment we’ve been looking for, finding that people with high Lp(a) levels who regularly take aspirin might significantly reduce their ASCVD mortality risks. The researchers analyzed 26-year outcomes from 2,990 people without clinical ASCVD (representative of 73M US adults), including 7% who regularly took aspirin, finding that… Among participants with high Lp(a) levels, daily aspirin-takers had far lower
Smidt Heart Institute and Cedars-Sinai, both based in Los Angeles, used the largest dataset to date to trained a machine-learning algorithm that can interpret echocardiogram images.
Both individual- and area-level social determinants of health (SDOH) are associated with atherosclerotic cardiovascular disease (ASCVD) risk, according to a study published in JAMA Network Open.
Atrial fibrillation (AF) is a progressive disease that often starts with predominately sinus rhythm interrupted by paroxysms of AF. As the left atrium becomes more diseased, it progresses into persistent AF and achieving rhythm and rate control becomes more difficult.
DALLAS, 1 de mayo, 2024 — Cada año, aproximadamente 800,000 personas en los Estados Unidos sufren un derrame cerebral.[1] La American Stroke Association, una división de la American Heart Association (la Asociación Americana del Corazón), reconoce a.
Careful regulation of the complement system is critical for enabling complement proteins to titrate immune defense while also preventing collateral tissue damage from poorly controlled inflammation. In the eye, this balance between complement activity and inhibition is crucial, as a low level of basal complement activity is necessary to support ocular immune privilege, a prerequisite for maintaining vision.
In this review of April 2024, the editorial team highlighted some of the biggest stories in the pulmonary health space, touching on topics such as air quality issues, asthma, and pneumonia.
DALLAS, 1 de mayo de 2024 — Cada 40 segundos alguien en los EE. UU. sufre un ataque o derrame cerebral[[1], y 1 de cada 4 supervivientes tendrá otro a lo largo de su vida[2].Durante mayo, el Mes del Derrame Cerebral en Estados Unidos, la American.
In this week’s View, Dr. Eagle looks at the durability of pulmonary vein isolation using pulsed-field ablation, then examines genetic penetrance of dilated cardiomyopathy in genotype-positive relatives.
The current approval is based on the VOLTAIRE-HCLF clinical trial, which examined the bioavailability of high-concentration (100 mg/mL) and low-concentration (50 mg/mL) formulations of adalimumab-adbm.
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