Sun.Feb 11, 2024

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TAVI Matches SAVR in Lower Risk Aortic Valve Patients: 10 year outcomes

Cardiology Update

The NOTION trial, a pioneering study, sought to compare the long-term clinical and bioprosthesis outcomes of Transcatheter Aortic Valve Implantation (TAVI) versus Surgical Aortic Valve Replacement (SAVR) in patients with severe aortic valve stenosis (AS) at lower surgical risk. The study, spanning a decade, enrolled 280 patients, randomly assigned to either TAVI with the CoreValve bioprosthesis or SAVR.

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Gastric Bypass Surgery’s Durable Hypertension Impact

CardiacWire

The associations between obesity and hypertension are widely known, but a new JACC study reveals that weight-reducing gastric bypass surgery has a significant and lasting impact on patients’ need for antihypertensives. The GATEWAY trial assigned 100 participants (76% women, 43.8 avg. age, 36.9 BMI) to receive Roux-en-Y gastric bypass and medical therapy or only receive medical therapy, finding that after five years… Far more gastric bypass patients cut their BP medication use by at least 30% (80

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The double burden: type 1 diabetes and heart failure—a comprehensive review

Cardiovascular Diabetology

Heart failure (HF) is increasing at an alarming rate, primary due to the rising in aging, obesity and diabetes. Notably, individuals with type 1 diabetes (T1D) face a significantly elevated risk of HF, leading.

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There's More We Could Be Doing for Patients in Pain, with Melanie Lewis, RN

HCPLive

Melanie Lewis, RN, writes about how listening to patients, conducting nerve conduction studies, and referring to specialists are key actions to provide effective care in patients dealing with chronic pain.

RN 98
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Swedish death cleaning isn’t only about death

Heart Sisters

"The Gentle Art of Swedish Death Cleaning" suggests that if we don't sort out our possessions now, we're condemning our families to do the job for us later.

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Female Patients with Psoriasis, Related Clinical Characteristics More Likely to Develop Psoriatic Arthritis

HCPLive

This retrospective cohort study suggests the potential benefits of greater use of screening, though additional research on these predictive factors may be necessary as well.

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Monitoring coronary blood flow by laser speckle contrast imaging after myocardial ischaemia reperfusion injury in adult and aged mice

Frontiers in Cardiovascular Medicine

Introduction Investigating coronary microvascular perfusion responses after myocardial infarction (MI) would aid in the development of flow preserving therapies. Laser speckle contrast imaging (LSCI) is a powerful tool used for real-time, non-contact, full-field imaging of blood flow in various tissues/organs. However, its use in the beating heart has been limited due to motion artifacts.

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Circulating biomarkers in the diagnosis and prognosis of immune checkpoint inhibitor-related myocarditis: time for a risk-based approach

Frontiers in Cardiovascular Medicine

Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that block immune checkpoints and therefore activate immune cells, allowing them to recognize and attack cancer cells. ICIs have revolutionized oncology practice, but their use has been complicated by immune-related adverse events (irAEs). Of cardiovascular (CV) irAEs, ICI-related myocarditis has received significant attention due to high mortality rates, ranging from 25% to 50%, despite its overall low incidence.

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Embolization Proves Its Mettle for Subdural Hematoma

Med Page Today

(MedPage Today) -- PHOENIX -- For chronic or subacute subdural hematoma, embolization of the middle meningeal artery (MMA) reduced recurrence, three randomized trials showed. Two trials with the Onyx liquid embolic system and one with the Squid.

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Deep learning denoising reconstruction for improved image quality in fetal cardiac cine MRI

Frontiers in Cardiovascular Medicine

Purpose This study aims to evaluate deep learning (DL) denoising reconstructions for image quality improvement of Doppler ultrasound (DUS)-gated fetal cardiac MRI in congenital heart disease (CHD). Methods Twenty-five fetuses with CHD (mean gestational age: 35 ± 1 weeks) underwent fetal cardiac MRI at 3T. Cine imaging was acquired using a balanced steady-state free precession (bSSFP) sequence with Doppler ultrasound gating.

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See What PM Cardio Digitization can do with this ECG

Dr. Smith's ECG Blog

This was a patient with chest pain. The ECG was faxed to a cardiologist. But it was very difficult for him to see. He showed this to me the next day.

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Pulmonary vein capture is a predictor for long-term success of stand-alone pulmonary vein isolation with cryoballoon ablation in patients with persistent atrial fibrillation

Frontiers in Cardiovascular Medicine

Background The mechanisms of AF development and progression are still not completely understood. Despite the relative efficacy of ablation, the risk of AF recurrence is substantial, particularly in patients with persistent AF (perAF). At present we do not have any reliable intra-procedural electrophysiologic predictors of long-term success of AF ablation other than pulmonary vein isolation.

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Regulation of overexpression lncRNA ATP2B1-AS1 on lung adenocarcinoma progression

Journal of Cardiothoracic Surgery

LncRNA ATP2B1-AS1 (ATP2B1-AS1) is involved in the occurrence and development of various diseases, while the relationship between lung adenocarcinoma (LUAD) and ATP2B1-AS1 is unclear. This study was to investig.

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Neuromuscular manifestations of wild type transthyretin amyloidosis: a review and single center’s experience

Frontiers in Cardiovascular Medicine

Transthyretin amyloidosis (ATTR) is a condition defined by accumulation of insoluble transthyretin amyloid deposits in multiple organs, especially in the peripheral nerve and heart muscle. ATTR may result from transthyretin mutations (variant ATTR or ATTRv) or may occur with normal transthyretin genotype (wild type ATTR or ATTRwt). ATTRwt was previously known as “senile amyloidosis” and causes cardiomyopathy which may lead to heart failure with a preserved ejection fraction, affecting predominan

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Association of the triglyceride glucose index with all-cause and cardiovascular mortality in a general population of Iranian adults

Cardiovascular Diabetology

The triglyceride glucose (TyG) index is a new and low-cost marker to determine insulin resistant which may be a predictor of cardiovascular disease (CVD). Although available evidence showed that its associatio.

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Up-regulated expression of two-pore domain K+ channels, KCNK1 and KCNK2, is involved in the proliferation and migration of pulmonary arterial smooth muscle cells in pulmonary arterial hypertension

Frontiers in Cardiovascular Medicine

Background Pulmonary arterial hypertension (PAH) is a severe and rare disease in the cardiopulmonary system. Its pathogenesis involves vascular remodeling of the pulmonary artery, which results in progressive increases in pulmonary arterial pressure. Chronically increased pulmonary arterial pressure causes right ventricular hypertrophy and subsequent right heart failure.

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The negative pressure wound therapy for prevention of sternal wound infection: Can we reduce infection rate after the use of bilateral internal thoracic arteries? A systematic literature review and meta-analysis

Journal of Cardiothoracic Surgery

Negative pressure wound therapy (NPWT) is traditionally used to treat postoperative wound infections. However, its use in closed wound sternotomy post cardiac surgery in high-risk patients has become increasin.

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The Feminine Face of Heart Disease 2024

Circulation

Circulation, Volume 149, Issue 7 , Page 489-491, February 13, 2024.

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The clinical value of P-wave terminal force in lead V1 in evaluating pericardial thickness in tuberculous constrictive pericarditis

Journal of Cardiothoracic Surgery

To investigate the relationship between p wave terminal force (Ptfv1) and pericardial thickness in patients with tuberculous constrictive pericarditis.

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Defining the Actionable Items in Women and Heart Disease: A Conversation With Nanette K. Wenger, MD

Circulation

Circulation, Volume 149, Issue 7 , Page 492-497, February 13, 2024.

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Protective Effect of CD137 Deficiency against Post-infarction Cardiac Fibrosis and Adverse Cardiac Remodeling via ERK1/2 Signaling Pathways

Journal of Cardiovascular Pharmacology

Myocardial fibrosis, a common complication of myocardial infarction (MI), is characterized by excessive collagen deposition and can result in impaired cardiac function. The specific role of CD137 in the development of post-MI myocardial fibrosis remains unclear. Thus, this study aimed to elucidate the effects of CD137 signaling using CD137 knockout mice and in vitro experiments.

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Opportunities in the Postpartum Period to Reduce Cardiovascular Disease Risk After Adverse Pregnancy Outcomes: A Scientific Statement From the American Heart Association

Circulation

Circulation, Volume 149, Issue 7 , Page e330-e346, February 13, 2024. Adverse pregnancy outcomes are common among pregnant individuals and are associated with long-term risk of cardiovascular disease. Individuals with adverse pregnancy outcomes also have an increased incidence of cardiovascular disease risk factors after delivery. Despite this, evidence-based approaches to managing these patients after pregnancy to reduce cardiovascular disease risk are lacking.

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Enhancing Transvenous Lead Extraction Risk Prediction: Integrating Imaging Biomarkers into Machine Learning Models

HeartRhythm

Machine learning (ML) models have been proposed to predict risk related to transvenous lead extraction (TLE).

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Multimodal Imaging Evidence for Optimized Blood Pressure Control Following Hypertensive Pregnancy: Mechanistic Insights Into Beneficial Cardiac Remodeling From the POP-HT Trial

Circulation

Circulation, Volume 149, Issue 7 , Page 542-544, February 13, 2024.

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Eighth Annual Go Red for Women Issue

Circulation

Circulation, Volume 149, Issue 7 , Page 487-488, February 13, 2024.