Wed.Oct 16, 2024

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Standing more may not reduce cardiovascular disease risk, could increase circulatory issues

Medical Xpress - Cardiology

Standing has gained popularity among people looking to offset the harms of a sedentary lifestyle often caused by spending long days sitting in front of the computer, television or driving wheel. Standing desks have become a popular option among office workers, and in other industries like retail, workers may opt to stand instead of sit.

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Standing more may not reduce cardiovascular disease risk, could increase circulatory disease, research finds

Science Daily - Heart Disease

New research has shown that over the long-term, standing more compared with sitting does not improve cardiovascular health (coronary heart disease, stroke and heart failure), and could increase the risk of circulatory issues related to standing, such as varicose veins and deep vein thrombosis.

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New laser light diagnostic tool quickly detects earliest sign of heart attack

Medical Xpress - Cardiology

With heart attacks, every second counts. A new blood test diagnoses them in minutes rather than hours and could be adapted as a tool for first responders and people at home.

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Study Highlights Respiratory Tract Infection, Wheeze Risk Factors in Preterm-Born Infants

HCPLive

This review provides an overview of current data on immune development and risk factors for preterm-born infant development of respiratory infections and wheezing.

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Native Hawaiian and Pacific Islander adults have high CVD mortality, research reveals

Medical Xpress - Cardiology

Native Hawaiian and Pacific Islander (NHPI) adults have a high rate of cardiovascular disease (CVD) mortality, according to a study published online Oct. 15 in the Annals of Internal Medicine.

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Clinical investigation into risk factors for delirium post-cardiac surgery and its implications for nursing intervention guided by behavior change theory

Journal of Cardiothoracic Surgery

This study explores the factors contributing to the occurrence of delirium following cardiac surgery and devises nursing strategies rooted in behavior change theory.

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High blood pressure reduces respiratory capacity due to hardening of bronchi, study shows

Medical Xpress - Cardiology

High blood pressure (hypertension) causes thickening of the blood vessels and hardening of the arteries (arteriosclerosis). A study conducted by Brazilian researchers has shown for the first time that a similar phenomenon occurs in the lungs. High blood pressure hardens the bronchi and increases airway resistance, impairing respiratory capacity.

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Study finds women more likely than men to die after heart surgery complications

Medical Xpress - Cardiology

Despite having no greater chance of developing problems after high risk cardiovascular surgery, women are more likely than men to die from postoperative complications, a University of Michigan-led study suggests.

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Tonix Pharma Submits NDA for TNX-102 SL, Potential Fibromyalgia Medication

HCPLive

Two pivotal phase 3 studies previously met their endpoints of significantly reducting daily pain compared with placebo.

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Study reveals insights into life quality for adults with heart disease

Medical Xpress - Cardiology

For the first time, adults living with congenital heart disease (CHD) now have valuable insights into their long-term quality of life through data from the Congenital Heart Initiative (CHI). CHI is the nation's first and largest patient-focused registry for adults with CHD and released its first study involving over 4,500 participants from all 50 states.

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Invention quickly detects earliest sign of heart attack

Science Daily - Heart Disease

With heart attacks, every second counts. A new blood test diagnoses them in minutes rather than hours and could be adapted as a tool for first responders and people at home.

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Hot news flash: Menopause can impact a woman's heart health

Medical Xpress - Cardiology

The risk of heart disease increases with age for most people, however, for women that may be even more true. The menopause transition, those years leading up to and through menopause, is a time of increasing heart disease risk, according to an American Heart Association scientific statement published in the flagship journal Circulation in 2020.

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Will Humans Live to 150? Not in Our Lifetime

Physiologically Speaking

If you could live to be 150 years old, would you? One’s answer to this question inevitably hinges on a few things: Whether they’ll arrive there in good health and whether they’ll get to enjoy longevity with friends and family whom they love. What’s the allure of immorality spent in isolation and despair? I, for one, would gladly jump at any opportunity that gave me a chance of nearly doubling the average human lifespan.

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Pulsed Field Ablation to Treat Paroxysmal AF

American College of Cardiology

What is the long-term safety and effectiveness of an integrated pulsed field ablation (PFA) system in a large United States–based drug-refractory symptomatic paroxysmal atrial fibrillation (AF) patient population?

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InCarda Gets Mixed Results in AFib Inhaler Trial

CardiacWire

AFib inhalers took a small step closer to becoming a reality after InCarda Therapeutics’ Phase 3 RESTORE-1 trial showed that its FlecIH-103 inhaled flecainide formulation can rapidly convert paroxysmal AFib to normal sinus rhythm. However, challenges with the study suggest that InCarda has more work to do in order to achieve this reality. FlecIH-103 is an orally-inhaled flecainide acetate solution that treats paroxysmal AFib (PAF) by rapidly restoring normal sinus rhythm (NSR), potentially reduc

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Ten Points to Remember From the Recent Scientific Statement on Aortopathy Management in Children

American College of Cardiology

The scientific statement titled "Cardiovascular Management of Aortopathy in Children" from the American Heart Association (AHA) provides a comprehensive overview of aortopathy in pediatric patients and a consensus statement regarding management.

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Left bundle branch area pacing for atrioventricular block and mild to moderately reduced left ventricular systolic function

Journal of Cardiovascular Electrophysiology

This multicenter observational study evaluated the impact of LBBAP on clinical outcomes and improvements in echocardiographic parameters among patients with atrioventricular block and a reduced LVEF of 36%–50%. LBBAP significantly improved LVEF without causing fatal ventricular arrhythmias. LVEF normalization (>50%) was achieved in 64.5% of patients, whereas patients without normalization demonstrated no deterioration in LVEF.

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AF Screening With a 14-Day ECG Monitor

American College of Cardiology

What is the frequency of atrial fibrillation (AF) and the distribution of AF burden found when screening individuals ≥70 years of age with a 14-day electrocardiograph monitor?

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Pre-Hospital Epinephrine More Common in Anaphylaxis Cases Treated at Home

HCPLive

Early epinephrine intervention at home can potentially successfully treat anaphylaxis in children without further treatment in a hospital setting.

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Semaglutide and BP, HF Risk Assessment Using Biomarkers, DAPT After Drug-Eluting Stenting in ACS

American College of Cardiology

In this week’s View, Dr. Eagle looks at an individual patient data meta-analysis of semaglutide and blood pressure (BP). He then explores an analysis from COMBINE-AF on heart failure (HF) risk assessment using biomarkers in patients with atrial fibrillation.

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Non-alcoholic fatty liver disease risk with GLP-1 receptor agonists and SGLT-2 inhibitors in type 2 diabetes: a nationwide nested case–control study

Cardiovascular Diabetology

Non-alcoholic fatty liver diseases (NAFLDs)/non-alcoholic steatohepatitis (NASH) are the most common liver disorders among patients with type 2 diabetes. Newer classes of glucose-lowering agents (GLAs), such a.

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Pulmonary Resection for Lung Cancer Risk Calculator

Society of Thoracic Surgeons - Surgeon

Resource Pulmonary Resection for Lung Cancer Risk Calculator gmckinney Wed, 10/16/2024 - 07:59 The new pulmonary resection for lung cancer risk calculator is engineered using contemporary data from the STS General Thoracic Surgery Database. It allows surgeons and multidisciplinary medical providers to estimate a patient’s individualized risk in real-time, based on specific factors such as tumor characteristics, comorbidities, and procedures performed.

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Endothelial cells derived extracellular vesicles promote diabetic arterial calcification via circ_0008362/miR-1251-5p/Runx2 axial

Cardiovascular Diabetology

Arterial calcification, an independent predictor of cardiovascular events, increases morbidity and mortality in patients with diabetes mellitus (DM), but its mechanisms remain unclear. Extracellular vesicles (.

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SMT Publishes Trial Results for Supraflex Cruz Stent

DAIC

tim.hodson Wed, 10/16/2024 - 09:00 Oct. 16, 2024 — Sahajanand Medical Technologies (SMT) recently announced the publication of the COMPARE 60/80 HBR trial results in Circulation: Cardiovascular Interventions , a journal of The American Heart Association. Led by Dr. Pieter C. Smits and a distinguished team of international researchers, the trial compares the performance of SMT's biodegradable-polymer sirolimus-eluting Supraflex Cruz stent with the biodegradable-polymer Ultimaster Tansei * s

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Circadian variation pattern of sudden cardiac arrest occurred in Chinese community

Open Heart

Background The circadian variation pattern of sudden cardiac arrest (SCA) occurred in Chinese community including both community healthcare centres and primary hospitals remains unknown. This study analysed the circadian variation of SCA in the Chinese community. Methods Data between 2018 and 2022 from the remote ECG diagnosis system of Xinhua Hospital affiliated to Shanghai Jiao Tong University School of Medicine were analysed to examine the circadian rhythm of SCA, stratified by initial shocka

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NFL Player Ambassadors urge fans to learn lifesaving CPR in 90 seconds

Medical Xpress - Cardiology

More than half of all people who experience sudden cardiac arrest outside of hospital don't receive immediate cardiopulmonary resuscitation (CPR). As a result, 9 out of 10 times they die. Yet it takes just 90 seconds to learn the fundamentals of Hands-Only CPR to save a life. CPR, especially if performed immediately, can double or triple a person's chance of survival.

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VUMC pediatric cardiology chief steps down

Becker's Hospital Review - Cardiology

David Bichell, MD, has stepped down as chief of the Division of Pediatric Cardiac Surgery and co-director of the Pediatric Heart Institute at Monroe Carell Jr. Children's Hospital at Nashville, Tenn.-based Vanderbilt University Medical Center.

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Study finds young adults at risk for large vessel occlusion strokes

Medical Xpress - Cardiology

New research published in the Journal of Stroke and Cerebrovascular Diseases confirms that strokes thought to happen in older adults are possible in the younger (defined as 18–50 years old) population. Large Vessel Occlusion Acute ischemic Strokes (LVO-AIS) are considered to be the most debilitating strokes which occur due to blockage of large cerebral arteries usually from blood clots or plaque build up.

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AMA Releases Statement Urging Congress to Address Medicare Reform During Lame Duck

DAIC

tim.hodson Wed, 10/16/2024 - 14:17 Oct. 15, 2024 — The American Medical Association recently released a statement urging Congress to address Medicare reform during the lame duck session later this year. In the statement, Bruce A. Scott, M.D. , President, American Medical Association, said: “The issue bringing together a divided Washington today is the awareness that Medicare patients must continue to have access to medical care.

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Clinical Guideines: The refuge of the destitute

Dr. Sanjay Gupta

The modern age of clinical guidelines began with a 1992 institute of medicine report which defined guidelines as systematically developed statements meant to assist practitioner and patient decisions about healthcare for specific clinical circumstances. The key words there were ‘assist practitioner AND patient decisions’. However over the course of the last 30 years, this seemingly innocuous and potentially helpful advancement/concept has metamorphosed into something which is far bigger and far

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MedTech Innovation Forum to Take Place at TCT 2024

DAIC

tim.hodson Wed, 10/16/2024 - 14:46 Oct. 11, 2024 – As the pace of change accelerates in healthcare, the most pressing questions in cardiovascular medicine demand immediate answers. These challenges and more will be tackled head-on at the third annual TCT MedTech Innovation Forum on Oct. 27, at the Walter E. Washington Convention Center in Washington, D.C.

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A Higher Form of Truth

Dr. Sanjay Gupta

Several years ago, I was invited to join a fellowship program at one of the most prestigious cardiac institutions in the USA. I recall that time as one filled with great joy (because I thought it would greatly help my career) but also in part tainted with some trepidation (because this place only attracted the best of best and I didnt think I was bright enough to be mingling with such people).

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CMS Updates Medicare Coverage for AI-Coronary Plaque Analysis

DAIC

tim.hodson Wed, 10/16/2024 - 12:36 Oct. 15 , 2024 — Four of the seven Medicare Administrative Contractors (MACs) have released final local coverage determinations (LCD) for AI-Coronary Plaque Analysis (AI-CPA). The four contractors for the U.S. Centers for Medicare and Medicaid Services (CMS) – including CGS, National Government Services (NGS), Palmetto GBA and Wisconsin Physicians Service Insurance Corporation (WPS) – provided updated LCDs for current procedural terminology (CPT) codes 0623T -

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What is Care

Dr. Sanjay Gupta

The concept of ‘caring’ in medicine can be metaphorically likened to actively choosing to walk the patient home. However ‘home’ in this setting refers to the place the patient calls home – Caring is not about walking the patient to the place that the doctor calls home. This is fundamentally the problem with modern day medical care. We try and walk the patient to ‘our home’ and not to ‘their’ home.

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Switching patients to JAK Inhibitors in Atopic Dermatitis in Clinical Practice

HCPLive

Medical experts rate dermatologists’ comfort with switching to JAK inhibitors and describe how frequently to switch patients from biologics to JAK inhibitors, including their treatment strategy for this population.

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Surviving Heart Attacks: The Importance of Cardiac Collateralisation

Dr. Sanjay Gupta

The Heart is a muscle and any muscle requires a blood supply to function. The heart is supplied by 2 main blood vessels. The left coronary artery and the right coronary artery. The left further divides into 2 large branches: The left anterior descending artery (LAD) and the left circumflex artery. Each of these vessels supply a part of the heart and in combination, these 3 vessels supply the whole of the heart.

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Treatment Breaks and Rescue Treatments in Atopic Dermatitis

HCPLive

Medical experts discuss how often patients with atopic dermatitis request treatment breaks, their monitoring approach during these breaks, and how to educate and counsel patients about treatment breaks and rescue treatments, including identifying suitable candidates.