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Nature Reviews Cardiology, Published online: 20 September 2024; doi:10.1038/s41569-024-01079-x A study using advanced single-cell technologies has broadened our understanding of the diversity and complexity of brain endothelial cells by uncovering new endothelial subtypes and transcriptional patterns. These findings offer insights into potential therapeutic targets and emphasize the need for further research on vascular lineages and neurovascular interactions.
tim.hodson Thu, 09/19/2024 - 09:42 Sept. 18, 2024 – Astellas Pharma Inc. recently announced that Digitiva, a non-invasive digital health solution for heart failure management, has been listed with the U.S. Food and Drug Administration (FDA). Digitiva is classified as a Class I Software as a Medical Device (SaMD) and is exempt from 510(k) premarket submission*.
COVID-19 vaccine-associated myocarditis (C-VAM) has a mild initial clinical course, but myocardial injury is common, according to a study published online in the October issue of eClinicalMedicine.
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Circulation, Ahead of Print. People who experience out-of-hospital cardiac arrest often require care at a regional center for continued treatment after resuscitation, but many do not initially present to the hospital where they will be admitted. For patients who require interfacility transport after cardiac arrest, the decision to transfer between centers is complex and often based on individual clinical characteristics, resources at the presenting hospital, and available transport resources.
Nature Reviews Cardiology, Published online: 20 September 2024; doi:10.1038/s41569-024-01072-4 In this Review, the authors describe the bidirectional crosstalk between lysosome biology and immune cell function and polarization, focusing on immunometabolic reprogramming in the context of atherosclerosis and highlighting knowledge gaps and potential therapeutic strategies targeting immune cell lysosomes.
Nature Reviews Cardiology, Published online: 20 September 2024; doi:10.1038/s41569-024-01072-4 In this Review, the authors describe the bidirectional crosstalk between lysosome biology and immune cell function and polarization, focusing on immunometabolic reprogramming in the context of atherosclerosis and highlighting knowledge gaps and potential therapeutic strategies targeting immune cell lysosomes.
Renton, Wash.-based Providence is planning a $42 million renovation of the Providence Heart Institute in Spokane, which will increase its patient capacity by 15%, according to a Sept. 17 report from the Spokane Journal of Business.
Lp(a) ordering remains low in patients at risk for ASCVD, particularly non-Hispanic Black or Hispanic individuals in socioeconomically disadvantaged neighborhoods.
Blog Managing Relationships with Patients KCummings Thu, 09/19/2024 - 10:19 Medical Student Resident / Fellow Early career cardiothoracic surgeons have many important relationships that need to be managed and developed. The patient relationship can be excellent, a source of pride and healing, or damaging, a source of stress and contempt. In training, there are many explicit lessons about technical parts of procedures and guidelines to follow, and publications to remember, but there are few expli
In this segment of his interview, Zirwas highlighted the use of JAK inhibitors such as upadacitinib, discussed safety, and touched on topical options for patients with eczema.
The U.S. Food and Drug Administration (FDA) has approved Eversense 365, the first and only continuous glucose monitoring (CGM) system designed to function for an entire year, according to a company press release. Developed by Senseonics and Ascensia Diabetes Care, the device represents a significant advancement in long-term glucose monitoring technology.
"Stay updated on the latest findings in cardiology, including the use of machine-learning models and genetic testing to improve patient care and outcomes.
The following are key points to remember from a state-of-the-art review on the established and emerging therapeutic role of mineralocorticoid antagonism in patients with heart failure (HF).
Is coronary artery calcium (CAC) density by computed tomography (CT) inversely associated with plaque vulnerability and atherosclerotic cardiovascular disease (ASCVD) events (coronary heart disease [CHD] and stroke)?
Lung cancer accounts for a significant proportion of cancer-related deaths in China, with the majority of the cases being classified as non-small cell lung cancer (NSCLC). The study aimed to investigate the ex.
Background The value of empirical superior vena cava isolation (SVCI) following pulmonary vein isolation (PVI) to improve the efficacy of radiofrequency catheter ablation (RFCA) for paroxysmal atrial fibrillation (PAF) remains controversial. Objective To evaluate the efficacy and safety of quantitative ablation index (AI)-guided empirical SVCI, in addition to PVI, for patients with PAF.
Background Type A aortic dissection (TAAD) with coronary involvement is rare but potentially fatal. Proper myocardial protection during surgery is essential. Case presentation Here, we describe a 52-year-old woman who presented with sudden chest pain. CT angiography revealed TAAD with right coronary artery involvement. During surgery, the proximal intima of the right coronary artery was found to be completely severed and everted.
Background Inflammation plays a pivotal role in atherogenesis and is a causal risk factor for atherosclerotic cardiovascular disease. Non-invasive coronary CT angiography (CCTA) enables evaluation of coronary plaque phenotype. This study investigates the relationship between a comprehensive panel of inflammatory markers and short-term plaque progression on serial CCTA imaging, hypothesising that inflammation is associated with increased plaque volume.
Myxomas are the most common primary benign heart tumors, typically found in the left atrium, with only 2–4% occurring in the right ventricle. Clinical presentations vary widely, including congestive heart fail.
A pharmaceutical gene therapy has shown promise in treating calmodulinopathy, a rare and hard-to-treat heart arrhythmia, according to a study published Aug. 19 in Circulation.
This interview with Culton featured a discussion of key challenges faced when treating patients with blistering diseases such as pemphigus and bullous pemphigoid.
The aorta, one of the "great arteries," carries blood away from the heart to support circulation throughout the body. However, sometimes a tear in the lining of the aorta can occur, and while this is uncommon, it often requires immediate treatment. That's why it's important for people to be aware of common risk factors and symptoms.
Shapiro spoke in his Maui Derm NP+PA Fall conference interview about differentiating between types of alopecia areata and about the potential use of JAK inhibitors.
How do patient-level factors, including race/ethnicity and county-level socioeconomic status (SES) affect inequities in prehospital care of patients with stroke?
Panelists discuss how switching to a biologic with a different mechanism of action can enhance clinical outcomes in patients with inadequate responses to tumor necrosis factor inhibitors.
Panelists discuss how continued cycling of tumor necrosis factor inhibitors (TNFis) without achieving remission can lead to complications like irreversible joint erosion, significantly diminishing patient quality of life, and explore why providers may persist with TNFis despite failure, access barriers to switching mechanisms of action, and treatment considerations for patients whose initial positive response to TNFis declines over time.
A study carried out at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid, Spain provides crucial information about the effect of cardiometabolic risk factors and subclinical atherosclerosis on the network of microvessels that irrigate the heart in symptom-free middle-aged individuals.
High-risk SAFE scores were linked to increased mortality, especially in participants with alcohol-associated liver disease, as this group demonstrated the worst survival.
Aortoesophageal fistula (AEF) secondary to thoracic aortic endovascular repair (TEVAR) is rare and fatal. The author reports the treatment methods and outcomes of 10 patients with a TEVAR graft infection and a.
In hypertrophic cardiomyopathy (HCM), 48-hour ambulatory monitoring has been standard practice to detect nonsustained ventricular tachycardia (NSVT), a sudden death risk marker. Extended wear ambulatory ECG devices have more recently utilized for monitoring HCM patients.
The goal of the Iberis-HTN trial was to assess the efficacy and safety of the multi-electrode, unipolar AngioCare Iberis renal denervation (RDN) system in patients with treatment-resistant primary hypertension (HTN) on a standardized three-drug regimen.
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