Wed.Jun 26, 2024

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More Evidence That Flu Is Linked to Heart Attacks

Med Page Today

(MedPage Today) -- Influenza infection was associated with an increased risk of acute myocardial infarction (MI), especially for those without a prior hospitalization for coronary artery disease (CAD), according to a Dutch observational case series.

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JACC to Serve Cardiovascular Community, Shape Future Under New Editor

DAIC

Harlan M. Krumholz, MD, SM, FACC milla1cf Wed, 06/26/2024 - 18:57 June 26, 2024 — The first issue of JACC , the flagship journal of the American College of Cardiology , under new Editor-in-Chief Harlan M. Krumholz , MD, SM, FACC, published this week, ushering in a new era of one of the world’s leading scholarly journals. “I envision JACC, with all its strengths, as a transformative platform for building community, elevating strong science, influencing clinical practice, supporting career devel

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FDA Approves Ensifentrine (Ohtuvayre) for COPD

HCPLive

Ensifentrine, a PDE3 and 4 inhibitor from Verona Pharma, was associated with significantly improved lung function and reduced COPD exacerbations over 24 weeks.

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Nationwide Coffee Recall; Aspirin Misuse Common; Gena Rowlands' Alzheimer's Disease

Med Page Today

(MedPage Today) -- Note that some links may require registration or subscription. Snapchill recalled all of its canned coffee products distributed nationwide through coffee roasters and retailers due to potential botulinum toxin contamination.

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Guselkumab Effective as Treatment for Facial, Genital Psoriasis

HCPLive

These data were identified to expand upon existing information regarding treatment options for facial psoriasis and/or genital psoriasis.

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Cardiovascular health could be biggest risk factor for future dementia rates

Medical Xpress - Cardiology

Dementia risk factors associated with cardiovascular health may have increased over time compared to factors such as smoking and having less education, finds a new study led by UCL researchers.

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Jennifer Goldman, RPh, PharmD: How Advances in Lipid Management Fit Into Diabetes Care

HCPLive

Jennifer Goldman, RPh, PharmD, discusses how the pharmacologic advancements in recent years have shifted discussion around lipid, and cardiovascular risk, management in diabetes.

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Systemic Light Chain Amyloidosis

The New England Journal of Medicine

Amyloidosis, a systemic disease that manifests in various ways, should be in the differential diagnosis of unexplained proteinuria, restrictive cardiomyopathy, peripheral and autonomic neuropathy, and hepatomegaly. Treatments are improving.

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More than a quarter of 'healthy' over-60s have heart valve disease, according to new research

Medical Xpress - Cardiology

The sheer scale of undiagnosed heart valve disease in our aging population has been revealed for the first time, thanks to new research led by the University of East Anglia.

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Plants for Joints: Multidisciplinary Lifestyle Intervention Shows Long-Term Benefit for RA

HCPLive

Findings from a 2-year extension of the Plants for Joints randomized controlled trial show promise for the long-term benefits of diet, physical activity, and stress management in RA.

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Autoimmune diseases and atherosclerotic cardiovascular disease

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 27 June 2024; doi:10.1038/s41569-024-01045-7 In this Review, Porsch and Binder discuss the evidence for and mechanisms of the increased and premature risk of atherosclerotic cardiovascular disease in patients with autoimmune disease, with particular focus on systemic lupus erythematosus and rheumatoid arthritis.

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Iron Deficiency Common in Newly Referred Patients With Renal Failure

HCPLive

Nearly half of patients with CKD presented with iron deficiency at the initial presentation at the nephrology department.

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IV Iron Repletion for Patients With HF and Iron Deficiency

American College of Cardiology

The following are key points to remember from a state-of-the-art review about intravenous (IV) iron repletion for patients with heart failure (HF) and iron deficiency.

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Positive Personality Traits May Impact Sleep Issues in Patients with RA

HCPLive

Positive personality traits and perceived disease impact may play a larger role in explaining sleep disturbances in patients with RA than disease activity, anxiety, or depression.

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ORFAN: FAI Score Obtained During CCTA, AI-Risk Algorithm Refine Risk Reclassification

American College of Cardiology

Coronary computed tomography (CCTA), used for first-line investigation of chest pain, has revealed there is a large group of individuals without obstructive coronary artery disease (CAD) for whom there is an unclear prognosis and management. Defining inflammatory risk using the perivascular fat attenuation index (FAI) Score has been shown to enhance clinical risk stratification and CCTA interpretation, according to results from the ORFAN study published May 29 in The Lancet.

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Patients with RA Have Greater Risk of Delayed Cervical, Prostate Cancer Screening

HCPLive

Patients with RA had a greater risk of delayed cervical cancer screening, and smoking was associated with a decrease in prostate cancer screening in patients with RA.

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Mid-term outcomes of endoscopic vein harvesting in coronary artery bypass grafting: a retrospective cohort study

Journal of Cardiothoracic Surgery

Endoscopic vein harvesting (EVH) is an alternative technique to obtain the saphenous vein for coronary artery bypass grafting (CABG) surgery. We aimed to evaluate the early and mid-term outcomes of patients wi.

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Deucravacitinib Safety Data and Treatment Selection Considerations

HCPLive

Bruce Strober, MD, PhD, and Linda Stein Gold, MD, provide clinical insights on long-term safety data for deucravacitinib and selecting the right treatment for the right patient.

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Retrograde cerebral embolism and pulmonary embolism caused by patent ductus arteriosus: a case report

Journal of Cardiothoracic Surgery

Although rare, paradoxical embolism sometimes occurs with patent ductus arteriosus (PDA). This study presents a case of PDA-associated paradoxical embolism with acute ischemic stroke (AIS) and pulmonary emboli.

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Transcatheter treatment of pure aortic regurgitation

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 27 June 2024; doi:10.1038/s41569-024-01059-1 Preliminary experience with the use of transcatheter aortic valve implantation (TAVI) to treat non-calcific aortic regurgitation has raised concerns about the short-term effectiveness of TAVI in this setting. A deeper understanding of the interaction between transcatheter heart valves and anatomy in patients with non-calcific aortic valve disease, coupled with the introduction of dedicated TAVI devices, is

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A massive pulmonary arteriovenous fistula complicated with coronary atherosclerotic heart disease treated by interventional therapy: a case report

Journal of Cardiothoracic Surgery

Pulmonary arteriovenous fistula (PAVF) is a rare disease, and its symptoms lack specificity. For patients with coronary heart disease(CHD), hypertension and other common cardiovascular diseases, PAVF is easy t.

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Gut microbiota: a potential new regulator of hypertension

Frontiers in Cardiovascular Medicine

Hypertension is a significant risk factor for cardiovascular and cerebrovascular diseases and has become a global public health concern. Although hypertension results from a combination of factors, the specific mechanism is still unclear. However, increasing evidence suggests that gut microbiota is closely associated with the development of hypertension.

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Systemic Therapies for Plaque Psoriasis

HCPLive

Dermatologists have a comprehensive discussion on systemic therapies for the treatment of plaque psoriasis, covering monitoring practices, and long term efficacy data for novel oral agent deucravacitinib.

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Role of inflammation and evidence for the use of colchicine in patients with acute coronary syndrome

Frontiers in Cardiovascular Medicine

Acute Coronary Syndrome (ACS) significantly contributes to cardiovascular death worldwide. ACS may arise from the disruption of an atherosclerotic plaque, ultimately leading to acute ischemia and myocardial infarction. In the pathogenesis of atherosclerosis, inflammation assumes a pivotal role, not solely in the initiation and complications of atherosclerotic plaque formation, but also in the myocardial response to ischemic insult.

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Use of Biologics in Pediatric Patients and Conversations with Parents

HCPLive

Robert Sporter, MD, discusses the initial conversations he has with pediatric patients and their parents when considering biologic therapies, addressing the risks associated with not treating the condition, such as compromised lung function and increased steroid use. He emphasizes the importance of communicating a comprehensive treatment plan, including contingencies for cases where a particular therapy may not be effective.

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In-office and At-Home Blood Pressure Measurement, Artificial Intelligence and Cardiovascular Care, Inflammatory Risk

American College of Cardiology

In this week’s View, Dr. Eagle looks at office measurement vs. ambulatory blood pressure monitoring and its associations with mortality in patients with or without diabetes.

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Biologic Options in Pediatric Asthma

HCPLive

The panel discusses the biologic drugs approved for use in children with asthma, including omalizumab, dupilumab, mepolizumab, and the recently approved benralizumab. They share their preferences among these options for improving lung function in pediatric patients.

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Low-Dose Aspirin for Prevention of Atherosclerotic CVD

American College of Cardiology

The following are key points to remember from a review on low-dose aspirin for the prevention of atherosclerotic cardiovascular disease (CVD).

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Beyond the Surface: Monitoring your Patients with Moderate to Severe Plaque Psoriasis

HCPLive

A panel of dermatologists have a comprehensive discussion on exciting developments in the treatment of plaque psoriasis, focusing on treatment approaches, patient monitoring strategies, and recent clinical trial data.

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Randomized Trial for Evaluation in Secondary Prevention Efficacy of Combination Therapy–Statin and Eicosapentaenoic Acid

American College of Cardiology

The goal of the RESPECT-EPA trial was to evaluate icosapent ethyl, a purified eicosapentaenoic acid (EPA), compared with control among patients with chronic coronary artery disease treated with statin therapy.

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Study Highlights Criteria for Early Abrocitinib Dose Increase for Eczema Patients

HCPLive

Following this post-hoc analysis, additional research may be necessary to assess other safety implications of a dose increase of abrocitinib for atopic dermatitis patients prior to Week 12.

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Thrombotic Microangiopathy in Snakebite Envenomation

BMH Medical Journal

Acute kidney Injury and Venom Induced consumption coagulopathy are known complications of snake bite envenomation. A small subset of such snakebite patients may develop thrombotic microangiopathy (TMA) which may go unrecognized if not looked for. If anaemia, thrombocytopenia and renal failure occurs despite normal coagulation parameters, a peripheral smear to look for haemolysis is warranted to identify the condition.

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High Anxiety Levels in RA Patients Linked to Increased Disease Activity

HCPLive

Presented at EULAR 2024, a study suggested controlling RA disease activity may be important from a psycho-social perspective.

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Decline in UK coronary heart disease rates offset by rise in other cardiovascular conditions

Medical Xpress - Cardiology

Rates of coronary heart disease in the UK have declined by about 30% over the past two decades, but this has been offset by rising rates of other conditions affecting the heart or blood vessels, finds a study in The BMJ today.

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Survey Context May Influence Estimates of US Vision Problem Prevalence

HCPLive

Inconsistent estimates of self-reported impairment across surveys could impact surveillance on the size of the population with vision problems.

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Peripheral Nerve Stimulation for MI Recovery: An Innovative New Frontier?

HeartRhythm

Peripheral electrical nerve stimulation (PENS) aims to modulate the central nervous system by activation of key peripheral nerves. This form electro-acupuncture neuromodulation, which holds the potential to foster the development of novel technologies in cardiology, traces its historical roots back to the practice of acupuncture in Chinese Medicine.

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Aquestive Therapeutics Epinephrine Sublingual Film Completes Temperature/pH Study

HCPLive

Aquestive Therapeutics announced positive topline data from the trial on June 25, 2024.

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