Fri.Apr 05, 2024

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Around 25% of Mild Asthma Patients Not Given Guideline-Directed Therapy, Despite Updates

HCPLive

This analysis highlights trends following the significant update made to the Global Initiative for Asthma and the National Heart Lung and Blood Institute asthma guidelines.

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Johnson and Johnson to Acquire Shockwave Medical

DAIC

Getty Images milla1cf Fri, 04/05/2024 - 09:57 April 5, 2024 — Johnson & Johnson and Shockwave Medical , Inc. today announced that they have entered into a definitive agreement under which Johnson & Johnson will acquire all outstanding shares of Shockwave for $335.00 per share in cash, corresponding to an enterprise value of approximately $13.1 billion including cash acquired.

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7 Things You Can Do To Reduce Your Risk Even If You Already Have Heart Disease.

Dr. Paddy Barrett

This newsletter focuses on prevention. A common feedback I get is that people with existing coronary artery disease feel like it doesn’t apply to them. They feel like they have ‘ missed the boat ’ They have not. And I will explain why. Arguably, applying the principles of prevention offers more bang for buck in the short term for people WITH coronary artery disease than those without coronary artery disease.

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Specialty Care Access Not Equal Among Teens With Diabetes

Med Page Today

(MedPage Today) -- Commercially insured youths with type 2 diabetes were less likely to see specialists compared with their counterparts with type 1 diabetes, a cross-sectional study of claims data indicated. In propensity score-weighted analyses.

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Antibiotic Prophylaxis and Infective Endocarditis Incidence Following Invasive Dental Procedures

JAMA Cardiology

This systematic review and meta-analysis evaluates associations between antibiotic prophylaxis and infective endocarditis following invasive dental procedures.

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Cardiomatics guide: Analyzing arrhythmias made easy

Cardiomatics

In a world where technology reigns supreme, one of the most profound tools in medicine remains the irreplaceable electrocardiogram (ECG). This noninvasive method provides a graphical visualization of millivolt potentials received by electrodes located on the patient’s skin. It can measure many aspects, from how fast the heart beats to how well its chambers conduct electrical energy.

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Inhaled NO at a crossroads in cardiac surgery: current need to improve mechanistic understanding, clinical trial design and scientific evidence

Frontiers in Cardiovascular Medicine

Inhaled nitric oxide (NO) has been used in pediatric and adult perioperative cardiac intensive care for over three decades. NO is a cellular signaling molecule that induces smooth muscle relaxation in the mammalian vasculature. Inhaled NO has the unique ability to exert its vasodilatory effects in the pulmonary vasculature without any hypotensive side-effects in the systemic circulation.

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Decreasing the Risk of Heart Failure in a Changing Post–Myocardial Infarction Environment

The New England Journal of Medicine

A number of therapies that have been shown to be effective in patients with chronic heart failure, including beta-blockers, mineralocorticoid receptor antagonists, and renin–angiotensin system inhibitors, have also been shown to be beneficial in patients with evidence of left ventricular systolic dysfunction, pulmonary congestion, or both after an acute myocardial.

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Balancing Innovation and Professionalism: The Emerging Role of AI-Powered Chatbots in Medical Consultation

HeartRhythm

The advent of artificial intelligence (AI) in healthcare has opened new frontiers in patient care and medical consultation. Among the most innovative applications of this technology are medical chatbots, which have the potential to revolutionize the way health advice and information are delivered to patients. By leveraging advanced algorithms and vast medical knowledge databases, these chatbots promise to provide immediate, accessible, and personalized medical advice.

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Older Adults with Vision Issues Report Lower Digital Technology Use

HCPLive

National data show older Americans with vision impairment were less likely to have access to digital technology than counterparts without impairments.

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ACC CardiaCast’s PulseCheck: Advanced Practice Provider Updates

American College of Cardiology

In this panel discussion, host Andrea Price MS, AACC brings together Martina Speight FNP-BC, MS, Jane Linderbaum ARNP, CNP, FACC and Bailey Estes MSN, AGNP-C to explore best practices related to structural heart disease.

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WHO Releases New Hepatitis B Guidelines

HCPLive

The 2024 HBV guidelines provide updated evidence-informed recommendations on key priority topics including treatment eligibility, diagnostics, and service delivery.

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ACC Practice Made Perfect: Manuscript Preparation from the Lens of an Editor

American College of Cardiology

In this episode, Editor-in-Chief of the ACC FIT section, Dr. Mohamad Khattab, interviews Dr. Julia Grapsa, who provides tips on how to publish your science from the perspective of an editor who regularly reviews manuscript submissions.

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Clinical Quiz: Gastrointestinal Evaluation of Iron Deficiency Anemia

HCPLive

This clinical quiz will test your knowledge of iron deficiency anemia, focused on the gastrointestinal evaluation of anemia based on recommendations from the AGA's 2020 guidelines.

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Analysis of the thickness characteristics of the left atrial posterior wall and its correlation with the low and no voltage areas of the left atrial posterior wall in patients with atrial fibrillation

Journal of Cardiothoracic Surgery

To analyze the relationship between the thickness of the left atrial posterior wall and the low and no voltage zones in the left atrial posterior wall in patients with atrial fibrillation (AF).

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Cardiovascular Research Foundation, CRF, Introduces New York Valves: The Structural Heart Summit

DAIC

milla1cf Fri, 04/05/2024 - 21:37 April 5, 2024 — The Cardiovascular Research Foundation (CRF) has announced New York Valves: The Structural Heart Summit , the expanded next iteration of our renowned annual Transcatheter Valve Therapy (TVT) conference. Taking place June 5-7, 2024, at the Jacob K. Javits Convention Center, North in New York City, the new summit will be a world-class educational experience in the field of structural heart interventions.

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Effective Apixaban removal using hemoadsorption during emergent open-heart surgery: a case report and narrative literature review

Journal of Cardiothoracic Surgery

The management of hemostasis in patients medicated with apixaban (Eliquis) undergoing emergency cardiac surgery is exceedingly difficult. The body’s natural elimination pathways for apixaban prove ineffective.

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Cardiawave is Presenting the 30-day Follow-up Results from its “Valvosoft Pivotal Study” on the Teatment of Severe Symptomatic Aortic Valve Stenosis at ACC24

DAIC

milla1cf Fri, 04/05/2024 - 21:34 April 5, 2024 — Cardiawave SA , a French medtech company that has developed an innovative Non-Invasive focused Ultrasound Therapy (NIUT) device for the treatment of severe symptomatic calcific aortic stenosis, will present the 30-day follow-up results for 60 patients enrolled in its European pivotal study to the 73rd annual conference of the American College of Cardiology in Atlanta, Georgia.

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Surgical management of multiple coronary artery to coronary sinus fistulas with giant left circumflex artery and multivalvular infective endocarditis

Journal of Cardiothoracic Surgery

Coronary artery fistula (CAF) is characterized as a congenital or acquired abnormal communication between a coronary artery and any of the four chambers of the heart (coronary–cameral fistula) or great vessels.

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CRG Introduces New York Valves: The Structural Heart Summit

DAIC

milla1cf Fri, 04/05/2024 - 21:37 April 5, 2024 — The Cardiovascular Research Foundation (CRF) is excited to introduce New York Valves: The Structural Heart Summit , the expanded next iteration of our renowned annual Transcatheter Valve Therapy (TVT) conference. Taking place June 5-7, 2024, at the Jacob K. Javits Convention Center, North in New York City, the new summit will be a world-class educational experience in the field of structural heart interventions.

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The Safety and Efficacy of Adalimumab Biosimilars in Inflammatory Diseases

HCPLive

Specialists in rheumatology, dermatology and gastrointestinal disease discuss clinical trials that have shown safety and efficacy of adalimumab biosimilars in inflammatory diseases.

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Physiology Friday #212: How Nighttime Alcohol Disrupts Normal Sleep Architecture

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. ICYMI On Monday, I posted a video interview that I recorded with Aidan Chariton from Shortcut U. We discuss the importance of endurance training and other things related to human health and performance. On Wednesday, I posted my “7 Rules for Health.” Details about the sponsors of this newsletter including Examine.com and my book “VO2 Max Essentials ” can be found at the end of the post!

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FDA Grants Nipocalimab Fast Track Designation for Rare Fetal Disease, with Katie Abouzahr, MD

HCPLive

Katie Abouzahr, MD, explains the transformative potential of nipocalimab for the treatment of patients with autoantibody-driven conditions.

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Stepping Away from the Monolith: The Disaggregation of Asian Cardiovascular Data

The American Journal of Cardiology

Publication date: Available online 4 April 2024 Source: The American Journal of Cardiology Author(s): Shruti Revankar, Anandita Agarwala

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Plaque Psoriasis as a Systemic Disease

HCPLive

Physician assistants TJ Chao and Kristine Kucera discuss how the understanding of plaque psoriasis has changed over time and is now considered a systemic disease.

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HDL Therapeutics — Time for a Curtain Call or Time to Reconceptualize?

The New England Journal of Medicine

The identification of an inverse association between high-density lipoprotein (HDL) cholesterol levels and incident cardiovascular disease events,1 combined with research on the role of HDL in reverse cholesterol transport, led to the exploration of therapies directed toward increasing HDL cholesterol. However, although therapies such as cholesteryl-ester transfer protein.

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Presentation of Generalized Pustular Psoriasis (GPP) in the Hospital

HCPLive

Dermatologists Drs Tina Bhutani and Scott Boswell discuss how patients with generalized pustular psoriasis (GPP) typically present in the hospital.

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Initiation and termination of a wide Complex Tachycardia by an atrial beat

HeartRhythm

A 28-year-old man with recurrent palpitations and no structural heart disease presented with a documented wide QRS complex tachycardia (WCT). He had a history of slow pathway ablation for atrioventricular nodal reentrant tachycardia three months ago. A standard electrophysiologic study was performed using multipolar-electrode catheters in the high right atrium, His bundle, right ventricular apex, and coronary sinus.

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Benefits of IL Therapies in Patients with PP

HCPLive

Experts discuss the landscape of IL therapies for the treatment of psoriasis, highlighting their improved safety and efficacy over prior agents.

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Focal atrial tachycardias originating from the aorta-mitral continuty: Anatomic and electrophysiological characteristics

HeartRhythm

The aorta-mitral annulus conjunction (AMC) is uncommon site of origin of focal atrial tachycardias (AT). Hence, the electrophysiological and ablation target characteristics are poorly described.

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Philip J Mease, MD: Bimekizumab Demonstrates Favorable Efficacy Compared with Other DMARDs for PsA

HCPLive

Philip J Mease, MD, highlights recent data comparing the safety and efficacy of bimekizumab with other DMARDs for the treatment of PsA.

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RISK OF INFECTION AND VASCULAR COMPLICATIONS WITH CARDIAC IMPLANTABLE ELECTRONIC DEVICES IMPLANTATION IN PATIENTS WITH A HISTORY OF MASTECTOMIES

HeartRhythm

Mastectomy with lymphadenectomy is a common surgical approach for patients with breast cancer. The risk of breast surgical site infection after mastectomy could be more than 10%1. Cardiovascular implantable electronic devices (CIED) implantation in these patients presents unique challenges due to the postoperative lymph node disturbance. However, there is currently no study assessing infection and vascular complication risks in these patients post-CIED implantation.

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Smartphone App Accurately Detects Frontotemporal Lobar Degeneration

HCPLive

A trial demonstrated the reliability and validity of a smartphone app’s capability of detecting frontotemporal lobar degeneration.

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Ectopic pancreas tissue in the posterior mediastinum

Journal of Cardiothoracic Surgery

The occurrence of ectopic pancreas in the mediastinum is rare. Herein, we report a 22-year-old female who presented with right shoulder pain, dysphagia, fever and headaches. Chest computer tomography revealed.

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The Oral Systemic Space of Plaque Psoriasis

HCPLive

TJ Chao and Kristine Kucera, PA’s go into dept of the recent developments in the systemic oral space of plaque psoriasis.

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The role of tubular cells in the pathogenesis of Fabry nephropathy

Frontiers in Cardiovascular Medicine

The pathophysiology of Fabry nephropathy (FN) is induced by galactosidase A deficiency with a chronic exposure of glycolipids to every lineage of renal cells. Tissue damage is attributed to the activation of molecular pathways, resulting in tissue fibrosis and chronic kidney disease. Podocytes have been the primary focus in clinical pathophysiological research because of the striking accumulation of large glycolipid deposits observable in histology.

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Biologics for Psoriasis: TNF Blockers

HCPLive

Experts discuss the use of TNF blockers in treating plaque psoriasis and their limited but important uses today.

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