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People with pockets of fat hidden inside their muscles are at a higher risk of dying or being hospitalized from a heart attack or heart failure, regardless of their body mass index, according to new research. This 'intermuscular' fat is highly prized in beef steaks for cooking. However, little is known about this type of body fat in humans, and its impact on health.
Nature Reviews Cardiology, Published online: 20 January 2025; doi:10.1038/s41569-025-01118-1 The past 20 years have witnessed remarkable progress in the evolution of transcatheter procedures for the treatment of adult patients with congenital heart disease. In this Review, Rods-Cabau and colleagues provide a comprehensive overview of the available transcatheter interventions for these patients, focusing on their current indications and associated outcomes.
Background Cardiogenic shock (CS) induced by severe aortic stenosis (AS) is a life-threatening condition with high mortality. Despite advancements in emergency interventions, the optimal treatment approach remains uncertain. Aim This study aimed to systematically review and analyse the existing evidence on outcomes of emergency transcatheter aortic valve implantation (eTAVI) and emergency balloon aortic valvuloplasty (eBAV) in CS patients.
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
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AimThe association between red cell distribution widthalbumin ratio (RAR) and the risk of all-cause mortality in intensive care unit (ICU) patients with heart failure remains uncertain. This study aimed to investigate this association.MethodsClinical data from MIMIC- (version 2.2) database was utilized for the analysis of ICU patients with heart failure.
Introduction Data on the characteristics and outcomes of pregnancy and among patients with Fontan physiology are limited. We aimed to evaluate the immediate and long-term outcomes among these patients who were followed at our centre. Methods We included adult patients who had undergone Fontan surgery for congenital heart disease and were pregnant between 1994 and 2021.
BackgroundImproving medication compliance and self-efficacy in hypertensive patients is of significant importance for their prognosis. This meta-analysis aimed to assess the role of motivational interviewing in reducing systolic and diastolic blood pressure, self-efficacy, quality of life and medication adherence in hypertensive patients.MethodsTwo authors searched PubMed, Cochrane Library, Clinicaltrials, Embase, Web of Science, China National Knowledge Infrastructure (CNKI), Chinese Biomedical
BackgroundImproving medication compliance and self-efficacy in hypertensive patients is of significant importance for their prognosis. This meta-analysis aimed to assess the role of motivational interviewing in reducing systolic and diastolic blood pressure, self-efficacy, quality of life and medication adherence in hypertensive patients.MethodsTwo authors searched PubMed, Cochrane Library, Clinicaltrials, Embase, Web of Science, China National Knowledge Infrastructure (CNKI), Chinese Biomedical
Patients on direct-acting oral anticoagulants (DOACs) are at high risk of perioperative bleeding complications. Intraoperative hemoadsorption is a novel strategy to reduce perioperative bleeding in patients on.
Pulmonary sequestration (PS) is a rare congenital lung developmental anomaly characterized by abnormal lung tissue that receives its blood supply from the aorta. Among the various types, mixed PSrepresents a distinct subtype. Currently, there is a lack of definitive reports regarding the specific management of this condition in infants and young children.
Hybrid coronary revascularisation benefits patients with multivessel disease, as it amalgamates the minimally invasive direct coronary artery bypass (MIDCAB) procedure and percutaneous coronary intervention (P.
BackgroundTuberous sclerosis complex (TSC) is a multisystem genetic disorder primarily characterized by the development of benign tumors in multiple organs. While cardiovascular involvement is less common than neurological or renal manifestations, it typically presents with cardiac rhabdomyomas (CRs). The co-occurrence of a bicuspid aortic valve (BAV) with TSC is exceedingly rare.Case summaryWe report the case of a 26-year-old woman with genetically confirmed TSC, harboring a novel pathogenic va
Cardiac tamponade often presents as external compression of the heart by pericardial fluid, leading to hemodynamic instability, but it can rarely be caused by compression by a solid mass. In this report, we present a case of tamponade-like physiology resulting from a large mediastinal tumor. This is an unusual phenomenon that is rarely described in the literature, and its optimal management remains controversial.
People with pockets of fat hidden inside their muscles are at a higher risk of dying or being hospitalized from a heart attack or heart failure, regardless of their body mass index, according to research published in the European Heart Journal.
Hyperglycemia is an independent risk factor for perioperative complications and mortality after cardiac surgery. Freestyle Libre Continuous glucose monitor (CGM) is an interstitial glucose monitoring system, w.
There are still gaps in the study of the miRNA and its SNPs in some diseases such as non-small cell lung cancer (NSCLC). The study aimed to provide useful information on the treatment of NSCLC by investigating.
IntroductionHypoxic liver injury (HLI) and Killip classification are poor prognostic factors in patients with ST-segment elevation myocardial infarction (STEMI). This study investigates the interrelationship between hypoxic liver injury (HLI) and Killip classification.Method and resultsA total of 1,537 STEMI patients who underwent percutaneous coronary intervention (PCI) from 2007 to 2014 at four tertiary hospitals in the Incheon-Bucheon province were enrolled in this study.
To assess the effectiveness and safety profiles of rivaroxaban compared to low molecular weight heparin (LMWH) in managing lower extremity deep vein thrombosis (DVT) subsequent to thoracoscopic lung cancer sur.
Cardiovascular disease (CVD) remains the leading cause of death worldwide, imposing a major burden on morbidity, quality of life, and societal costs, making prevention of CVD a top public health priority. Extensive research has pointed out that lack of adequate physical activity in life is one of the key risk factors for heart disease. Indeed, moderate exercise is not only beneficial to the heart in healthy populations, but also exerts a protective effect in pathological states.
Background Growth differentiation factor 15 (GDF15) is a cytokine responding to oxidative stress and inflammation, and it regulates appetite and energy balance. The association between GDF15 and clinical factors and its prognostic value in elderly multimorbid patients with heart failure with preserved ejection fraction (HFpEF) have not been well unknown.
A 13-year-old child presented with specific facial features, overgrowth, and intellectual disability. Echocardiography revealed the presence of a large pericardial effusion, left ventricular enlargement, mitral annular separation, and mitral valve prolapse with moderate regurgitation. These symptoms suggested a possible genetic disorder. High-throughput sequencing revealed a specific mutation in the DNMT3A gene (NM_175629.2:c.2408+1G>A) associated with Tatton-BrownRahman syndrome.
Aims This study aimed to determine the robustness, reproducibility and representativeness of the landmark Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (AF) (ARISTOTLE) and Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in AF (ROCKET AF) randomised trials through replication in an observational AF patient registry.
BackgroundSystemic inflammation plays a vital role in the pathogenesis and prognosis of cardiovascular disease (CAD). The systemic immune-inflammation index (SII) has been developed as a cost-effective and practical predictor for CAD outcomes. This study aimed to determine the association between the SII and the risk of ISR among ACS patients with and without diabetes mellitus (DM).MethodsIn this retrospective cohort study, a total of 1,652 patients who underwent percutaneous coronary interventi
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