Ken Grauer, MD

DECEMBER 1, 2023

== CLICK HERE — for a V ideo presentation of this case! ( 19:40 min. ) Below are slides used in my video presentation. For full discussion of this case — See ECG Blog #351 — == The ECG in Figure-1 — was obtained from a previously healthy older man who contacted EMS ( E mergency M edical S ervices ) because of "chest tightness" that began ~1 hour earlier.

Blog 167

Blog STEMI Ischemia 167

Physiologically Speaking

DECEMBER 1, 2023

Greetings! Welcome to the Physiology Friday newsletter. This newsletter is brought to you by Examine.com — the best place on the internet for health and nutrition information — and my new eBook, “VO2 Max Essentials.” Details can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.

Exercise 98

Exercise Physiology BMI Cholesterol 98

Cassling

DECEMBER 1, 2023

As Cassling continues to grow, we’re always evolving to better serve our customers. One way we’re doing this is by expanding our equipment service offerings. Expanded service is an ask that came from our customers, and it is a direct result of the trust and confidence they have in dedicated field service engineers like Jeremy Long.

Blog 97

Blog 97

Med Page Today

DECEMBER 1, 2023

(MedPage Today) -- Among younger patients undergoing total hip or knee replacement, whether they received aspirin versus direct oral anticoagulants (DOACs) did not seem to affect their risk of venous thromboembolism (VTE) following surgery, a large.

95

95

Journal of the American Heart Association

DECEMBER 1, 2023

Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023. BackgroundAn increased risk of recurrent stroke is noted in patients with atrial fibrillation despite direct oral anticoagulant (DOAC) use. We investigated the efficacy and safety of treatment with each of 4 different DOACs or warfarin after DOAC failure.Methods and ResultsWe retrospectively analyzed patients with atrial fibrillation with ischemic stroke despite DOAC treatment between January 2002 and December 201

Atrial Fibrillation 75

Atrial Fibrillation Hemorrhage Pharmacology Stroke 75

Med Page Today

DECEMBER 1, 2023

(MedPage Today) -- A custom artificial intelligence (AI) app for insulin management advice helped patients with type 2 diabetes gain rapid glycemic control, a small randomized clinical trial found. In titrating basal insulin, those who used a.

Diabetes 95

Diabetes 95

Journal of the American Heart Association

DECEMBER 1, 2023

Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023. BackgroundThe relationship between resting heart rate (RHR) and the risk of end‐stage renal disease (ESRD) among those without cardiovascular disease remains unclear. We aim to establish temporal consistency and elucidate the independent relationship between RHR and the risk of ESRD.Methods and ResultsThis cohort enrolled participants from 476 347 individuals who had taken part in a screening program from 1996 to

Risk Factors 75

Risk Factors Cardiovascular Disease Kidney Disease Hypertension 75

Journal of the American Heart Association

DECEMBER 1, 2023

Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023. BackgroundThe incidence and type of complications following catheter ablation of atrial fibrillation have been extensively examined, but the impact associated with these complications on the length of stay and hospitalization costs is unknown.Methods and ResultsThis cohort study included 20 117 adult patients (mean age 62.6±11.4 years, 30.3% women, median length of stay 1 day [interquartile range 1–2 days]) underg

Atrial Fibrillation 72

Atrial Fibrillation Hospital Ablation Reimbursement 72

Dr. S. Venkatesan MD

DECEMBER 1, 2023

Is it a physiological molecule ? 1.Yes, It is a physiological molecule. 2.No, Amyloid is always pathological. Where does it gets deposited ? A.Extracellular* B. Intracellular C. Both Answer : Q 1: A / Q 2: C. It is indeed a physiological molecule in small amounts that help carry hormones across the blood. In pathology, it accumulates in huge amounts.

Physiology 52

Physiology 52

Journal of the American Heart Association

DECEMBER 1, 2023

Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023.

Kidney Disease 72

Kidney Disease 72

Journal of Cardiovascular Electrophysiology

DECEMBER 1, 2023

Abstract Introduction The major limitation of the current cryoballoon (CB) system is a fixed 28 mm balloon-size. We sought to analyze real-world early experience with novel-sized adjustable CB. Methods This multicenter observational study included 140 consecutive atrial fibrillation patients (71 years, 94 men, 86 paroxysmal) who underwent pulmonary vein (PV) isolation using expandable diameter CB capable of ablation at 28 or 31 mm.

Atrial Fibrillation 40

Atrial Fibrillation Ablation Pulmonary Article 40

Journal of the American Heart Association

DECEMBER 1, 2023

Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023. BackgroundEvery year the American Heart Association's Resuscitation Science Symposium (ReSS) brings together a community of international resuscitation science researchers focused on advancing cardiac arrest care.Methods and ResultsThe American Heart Association's ReSS was held in Chicago, Illinois from November 4th to 6th, 2022.

Research 40

Research Cardiac Arrest 40

Journal of Cardiovascular Electrophysiology

DECEMBER 1, 2023

Abstract Introduction Severe transitory episodes of bradycardia with subsequent syncope in children are common, and generally portend a benign prognosis. Rarely, patients may experience prolonged asystolic episodes secondary to significant sinus pauses (SP) or paroxysmal atrioventricular block (AVB). Cardioneuroablation (CNA) is a catheter-based intervention, used to identify and ablate the epicardial ganglionated plexi (GP), which results in disruption of the vagal-mediated parasympathetic inpu

Pediatrics 40

Pediatrics Document Bradycardia Pacemaker 40

Journal of the American Heart Association

DECEMBER 1, 2023

Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023. BackgroundBlood pressure (BP) thresholds for diagnosing and managing hypertension vary for office, home, and ambulatory readings, and between guideline documents. This analysis determined corresponding office, home, and ambulatory BP thresholds using baseline data from the HI‐JAMP (Home‐Activity Information and Communication Technology–Based Japan Ambulatory Blood Pressure Monitoring Prospective) study, which used

Blood Pressure 40

Blood Pressure Hypertension Document Technology 40

European Journal of Heart Failure

DECEMBER 1, 2023

Abstract Background Extracellular matrix remodeling is one of the key pathways involved in heart failure (HF) progression. SGLT2 inhibitors may have a role in attenuating myocardial fibrosis. The impact of SGLT2 inhibitors on blood markers of collagen turnover in humans is not fully elucidated. Aims To investigate the effect of empagliflozin on serum markers of collagen turnover in patients enrolled in the EMPEROR-Preserved and EMPEROR-Reduced trials.

Heart Failure 40

Heart Failure Biomarkers Kidney Disease Atrial Fibrillation 40

Journal of the American Heart Association

DECEMBER 1, 2023

Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023. BackgroundTemporal trends in the management of acute coronary syndrome complicated with cardiogenic shock after the revision of guideline recommendations for intra‐aortic balloon pump (IABP) use and the approval of the Impella require further investigation, because their impact remains uncertain.Methods and ResultsUsing the Japanese Percutaneous Coronary Intervention (J‐PCI) registry database from 2019 to 2021, we

Cardiogenic Shock 40

Cardiogenic Shock Outcomes Aortic Hospital 40

Circulation: Cardiovascular Quality & Outcomes

DECEMBER 1, 2023

Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. Background:Traditional cardiac rehabilitation (CR) improves cardiovascular outcomes and reduces mortality, but less is known about the relative benefit of intensive CR (ICR) which incorporates greater lifestyle education through 72 sessions (versus 36 in CR). Our objective was to determine whether ICR is associated with a mortality and cardiovascular benefit compared with CR.Methods:Retrospective cohort study of Medicare Fee-For-S

Cardiac Rehabilitation 40

Cardiac Rehabilitation Medicare Outcomes Hospital 40

Journal of the American Heart Association

DECEMBER 1, 2023

Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023. BackgroundBrain arterial diameters (BADs) are novel imaging biomarkers of cerebrovascular disease, cognitive decline, and dementia. Traditional vascular risk factors have been associated with BADs, but whether there may be genetic determinants of BADs is unknown.Methods and ResultsThe authors studied 4150 participants from 6 geographically diverse population‐based cohorts (40% European, 14% African, 22% Hispanic,

Cerebrovascular Disease 40

Cerebrovascular Disease Dementia Biomarkers Risk Factors 40

Dr. Smith's ECG Blog

DECEMBER 1, 2023

Pendell and I have taught the queen on over 40,000 EKGs so far. Version 1 was bases on ~20,000. Version 2 will be coming out soon, also taught on an additional 20,000 EKGs. For version 3, we have started teaching her on yet more EKGs. These ones are EKG that the Queen's users uploaded, and on the comments and outcomes that they give. These EKGs are displayed on a platform with a pick list of diagnoses.

Outcomes 52

Outcomes 52

Journal of the American Heart Association

DECEMBER 1, 2023

Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023. BackgroundThe modified Blalock‐Taussig‐Thomas shunt is the gold standard palliation for securing pulmonary blood flow in infants with ductal‐dependent pulmonary blood flow. Recently, the ductus arteriosus stent (DAS) has become a viable alternative.Methods and ResultsThis was a retrospective multicenter study of neonates ≤30 days undergoing DAS or Blalock‐Taussig‐Thomas shunt placement between January 1, 2017 and

Pediatrics 40

Pediatrics Pulmonary Stent Stents 40

Physiologically Speaking

DECEMBER 1, 2023

To read the newsletter version of this post, follow the link below.

Physiology 52

Physiology Exercise 52

Journal of the American Heart Association

DECEMBER 1, 2023

Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023. BackgroundCoronary computed tomography angiography is increasingly used as the first‐line test for suspected coronary artery disease. Its overuse in a low pretest probability (PTP) population may lead to low diagnostic yield without change in patient management. We evaluated the clinical consequences of the updated 2019 European Society of Cardiology (ESC) chronic coronary syndromes guidelines’ PTP estimation and

Coronary Artery Disease 40

Coronary Artery Disease Myocardial Infarction Angina Hospital 40

Physiologically Speaking

DECEMBER 1, 2023

To read the newsletter version of this post, follow the link below.

Physiology 52

Physiology Exercise 52

Journal of the American Heart Association

DECEMBER 1, 2023

Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023.

Blood Pressure 45

Blood Pressure 45

Circulation: Heart Failure

DECEMBER 1, 2023

Circulation: Heart Failure, Ahead of Print.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Exercise Circulation 40

Journal of the American Heart Association

DECEMBER 1, 2023

Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023. BackgroundAlthough individuals with cancer experience high rates of cardiovascular morbidity, there are limited data on the potential differences in cardiovascular health (CVH) metrics between individuals with and without cancer.Methods and ResultsThe National Health and Nutrition Examination Survey between 2015 and 2020 was queried to evaluate the prevalence of health metrics that comprise the American Heart Asso

Cancer 40

Cancer Diet 40

Journal of the American Heart Association

DECEMBER 1, 2023

Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023. BackgroundSocioeconomic status (SES) is associated with cardiovascular health (CVH). Potential differences by sex in this association remain incompletely understood in Black Americans, where SES disparities are posited to be partially responsible for cardiovascular inequities.

Education 40

Education Medicaid Blood Pressure Medicare 40