Sun.Mar 23, 2025

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Association between triglyceride–glucose index and mortality in critically ill patients with atrial fibrillation: a retrospective cohort study

Cardiovascular Diabetology

The triglycerideglucose (TyG) index, an emerging surrogate marker of insulin resistance, has been implicated in adverse cardiovascular outcomes. However, its prognostic value in critically ill patients with a.

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Waiting, worrying and medical test results.

Heart Sisters

“Worry never robs tomorrow of its sorrow. It only saps today of its joy. ” ~ Dr.

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The prognostic significance of stress hyperglycemia ratio in evaluating all-cause and cardiovascular mortality risk among individuals across stages 0–3 of cardiovascular–kidney–metabolic syndrome: evidence from two cohort studies

Cardiovascular Diabetology

The American Heart Association (AHA) proposed the concept of cardiovascularkidneymetabolic (CKM) syndrome, underscoring the interconnectedness of cardiovascular, renal, and metabolic diseases. The stress hyp.

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Unmet Needs in Wilson Disease, with Sammy Saab, MD, MPH

HCPLive

Saab describes historical and ongoing unmet needs in Wilson disease, highlighting recent progress but also the need for a streamlined diagnosis.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Coupling Interval Counts in Ventricular Premature Depolarizations During Acute Ischemia

Circulation

Circulation, Volume 151, Issue 12 , Page 884-886, March 25, 2025.

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HCPLive 5 Stories in Under 5: Week of 03/16

HCPLive

An audio recap of the top 5 stories in healthcare news from the week of 03/16-03/23.

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More Trending

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April 2025 Stroke Highlights

Stroke Journal

Stroke, Volume 56, Issue 4 , Page 807-807, April 1, 2025.

Strokes 40
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Highlights From the Circulation Family of Journals

Circulation

Circulation, Volume 151, Issue 12 , Page 878-883, March 25, 2025.

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Hematoma Expansion in Intracerebral Hemorrhage: Time Is the Enemy

Stroke Journal

Stroke, Volume 56, Issue 4 , Page 848-849, April 1, 2025.

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Ganglionic Inflammation in a Patient With Takotsubo Syndrome

Circulation

Circulation, Volume 151, Issue 12 , Page 890-892, March 25, 2025.

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Correction to: Randomized Study Comparing First-Line Dual Versus Single-Stent Retriever Technique: TWIN2WIN

Stroke Journal

Stroke, Volume 56, Issue 4 , Page e129-e129, April 1, 2025.

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Response by Zhao et al to Letters Regarding Article, “Intracranial Atherosclerotic Disease and Incident Dementia: The ARIC Study (Atherosclerosis Risk in Communities)”

Circulation

Circulation, Volume 151, Issue 12 , Page e766-e766, March 25, 2025.

Article 45
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Submaximal Angioplasty for Severe Intracranial Atherosclerotic Stenosis: Benefit of Revascularization at Last

Stroke Journal

Stroke, Volume 56, Issue 4 , Page e114-e118, April 1, 2025. Intracranial atherosclerotic stenosis is a leading cause of stroke with a significant risk of recurrent ischemic events despite aggressive medical management. The longstanding benefits of percutaneous angioplasty and stenting in coronary artery disease, where atherosclerosis is the overarching cause in nearly all cases, provided a compelling rationale for exploring similar interventions in intracranial atherosclerotic stenosis.

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Letter by Xu et al Regarding Article, “Intracranial Atherosclerotic Disease and Incident Dementia: The ARIC Study (Atherosclerosis Risk in Communities)”

Circulation

Circulation, Volume 151, Issue 12 , Page e765-e765, March 25, 2025.

Article 45
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Map3k3  I441M Knock-In Mouse Model of Cerebral Cavernous Malformations

Stroke Journal

Stroke, Volume 56, Issue 4 , Page 1010-1025, April 1, 2025. BACKGROUND:Cerebral cavernous malformations (CCMs) refer to vascular dysplasia primarily found in the brain, affecting 0.5% of the population. A somaticMap3k3I441Mmutation has been found in 40% of patients with sporadic CCMs, which were typically accompanied by somatic gain-of-function mutations inPIK3CA.

Strokes 40
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Letter by Wei and Yu Regarding Article, “Intracranial Atherosclerotic Disease and Incident Dementia: The ARIC Study (Atherosclerosis Risk in Communities)”

Circulation

Circulation, Volume 151, Issue 12 , Page e764-e764, March 25, 2025.

Article 45
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Diffusion Imaging Protocol Heterogeneity Biases Ischemic Core Volume, Location, and Clinical Associations in Acute Stroke

Stroke Journal

Stroke, Volume 56, Issue 4 , Page 915-925, April 1, 2025. BACKGROUND:Diffusion-weighted magnetic resonance imaging is essential for diagnosing ischemic stroke and identifying targets for emergency revascularization. Apparent diffusion coefficient (ADC) maps derived from diffusion-weighted magnetic resonance imaging are commonly used to locate the infarct core, but they are not strictly quantitative and can vary across platforms and sites due to technical factors.

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Clinical Interpretation of Statistical Interaction

Circulation

Circulation, Volume 151, Issue 12 , Page 811-813, March 25, 2025.

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When ACS care is very delayed, "STEMI metrics" can be perfect. And how specific is Queen of Hearts?

Dr. Smith's ECG Blog

Written by Pendell Meyers, sent by anonymous, with additions by Smith A man in his 40s had acute chest pain and called EMS. EMS arrived and recorded this ECG: What do you think? Here is the PMcardio Queen of Hearts interpretation of the ECG: STEMI equivalent detected. Inferior and posterior OMI without STEMI criteria. If you think the Queen of Hearts is so sensitive because it sacrifices specificity, you would be wrong.

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Impact of mineralocorticoid receptor antagonists on the risk of sudden cardiac death across cardio‐kidney‐metabolic diseases: A meta‐analysis of randomized clinical trials

European Journal of Heart Failure

Abstract Aims Sudden cardiac death (SCD) is a prevalent cause of mortality among patients with cardio-kidney-metabolic (CKM) diseases. Mineralocorticoid receptor antagonists (MRAs) reduce the risk of SCD in patients with left ventricular dysfunction, but it is unclear if similar effects are expected across different CKM risk populations irrespective of ejection fraction.

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An Unpredictable Atrioventricular Accessory Pathway: Low‐Risk or High‐Risk?

Journal of Cardiovascular Electrophysiology

ABSTRACT A 66-year-old man with known asymptomatic preexcitation was admitted to our department for symptomatic complete infranodal atrioventricular block and scarce intermittent anterograde conduction through the atrioventricular accessory pathway. The accessory pathway was not further stratified due to evidence of intermittent conduction with a sinus node heart rate of 60bpm, and a bicameral pacemaker was implanted.

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Differences Between the Unipolar Versus Bipolar Potential‐Based Activation Maps of Ventricular Premature Contractions Arising From Ventricular Outflow Tracts

Journal of Cardiovascular Electrophysiology

ABSTRACT Background The use of an automated annotation algorithm based on the maximal negative derivative of the unipolar potential (dV/dTmax) for local activation timing in the ablation of outflow tract (OT) ventricular premature contractions (VPCs) remains controversial. Objective To investigate the spatial differences in the earliest activation sites (EASs) of OT-VPCs identified by an automated annotation based on unipolar dV/dTmax versus manual annotation using local bipolar potentials.