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The approval is based on data from a pair of phase 3 studies and makes risankizumab-rzaa the first IL-23 specific inhibitor approved for both ulcerative colitis and Crohn’s disease.
The over-the-counter supplement nicotinamide riboside, a form of vitamin B3, increased the walking endurance of patients with peripheral artery disease, a chronic leg condition for which there are few effective treatments.
Dr. Jesse McLaren illustrates the paradigm shift from STEMI to Occlusion MI (OMI) through 9 cases, and drives home the points that if there is STEMI criteria, consider false positives (eg. secondary and proportional to LVH or BER); if there is no STEMI criteria, consider false negatives and look for other signs of occlusion (eg. acute Q waves or loss of R waves, hyperacute T waves, or reciprocal STD/TWI) and if the ECG is nondiagnostic, consider other OMI signs including clinical (refractory isc
(MedPage Today) -- Women with perinatal depression (PND) had a higher risk of cardiovascular disease (CVD) in middle adulthood than matched parous women without PND, a Swedish nationwide study found. Over a mean of 10.4 years, women with PND had.
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
To evaluate the association between diabetic foot disease (DFD) and the incidence of fatal and non-fatal events in individuals with type 2 diabetes (T2DM) from primary-care settings.
The over-the-counter supplement nicotinamide riboside, a form of vitamin B3, increased the walking endurance of patients with peripheral artery disease, a chronic leg condition for which there are few effective treatments.
Getty Images milla1cf Tue, 06/18/2024 - 19:56 June 18, 2024 — As we commemorate Juneteenth 2024, JACC , the flagship journal of the American College of Cardiology , has published “Excess Cardiovascular Mortality Among Black Americans 2000-2022: A Report Card,” to highlight the persistent and tragic inequities in cardiovascular care and put in human terms the years of life lost to the Black community because of their higher cardiovascular disease death rates.
Getty Images milla1cf Tue, 06/18/2024 - 19:56 June 18, 2024 — As we commemorate Juneteenth 2024, JACC , the flagship journal of the American College of Cardiology , has published “Excess Cardiovascular Mortality Among Black Americans 2000-2022: A Report Card,” to highlight the persistent and tragic inequities in cardiovascular care and put in human terms the years of life lost to the Black community because of their higher cardiovascular disease death rates.
(MedPage Today) -- A community-based intensive blood pressure (BP) intervention was safe and effective for both older and younger adults with hypertension, a randomized trial conducted in rural China showed. Among participants ages 60 and older.
milla1cf Tue, 06/18/2024 - 20:01 June 18, 2024 — Positron Corporation , a leading molecular imaging medical device company offering PET and PET-CT (Positron Emission Tomography/Computed Tomography) imaging systems and clinical services, is pleased to welcome a prominent cardiovascular practice in Michigan as a new customer utilizing Positron’s Attrius PET System and services.
Findings suggest machine learning models may have promising utility in IgAN, highlighting the superior diagnostic performance of certain models versus standard logistic regression.
Elixir Medical has announced the company’s novel bioadaptive implant, DynamX Sirolimus-Eluting Coronary Bioadaptor System, has been granted Breakthrough Device Designation by the U.S. Food and Drug Administration (FDA). The designation recognizes the novelty of the technology and the potential to provide a more effective treatment option for patients with coronary artery disease.
(MedPage Today) -- Over one in 10 cardiology practices in several states -- Rhode Island, Nevada, Louisiana, Arizona, Oklahoma, Texas, and Florida -- have been acquired by private equity. (JAMA Health Forum) Workplace sexual harassment was.
A projected rise in heart disease and stroke – along with several key risk factors, including high blood pressure and obesity – is likely to triple related costs to $1.8 trillion by 2050, according to two presidential advisories published in the AHA journal Circulation. christine.book Tue, 06/18/2024 - 11:22 June 18, 2024 — At least 6 in 10 adults in an older, more diverse U.S. population could be affected by cardiovascular disease within the next 30 years, according to two new science reports.
Black Americans suffered nearly 800,000 excess age-adjusted deaths and 24 million excess years of potential life lost due to cardiovascular disease from 2000 to 2022, compared with their White counterparts.
In this month's EM Quick Hits podcast: Megan Landes on the importance of diagnosing HIV in the ED, Jesse McLaren on the failed paradigm of STEMI criteria and ECG tips to identify acute coronary occlusion, Anand Swaminathan on evidence for non-invasive airway management in the poisoned patient, Brit Long and Hans Rosenberg on the identification, workup and management of spontaneous bacterial peritonitis, Matt Pointer on the most lucrative side-gig, DIY investing.
New research from the SOLOST-WHF trial suggests sotagliflozin is a cost-effective treatment for diabetes patients with recent heart failure, with high cost-effectiveness probability.
Tremendous enthusiasm about mitral annulus disjunction (MAD) emerged in 2018 when Dejgaard et al. showed that, in their cohort of patients with mitral valve prolapse (MVP), MAD was associated with an increased risk of malignant ventricular arrhythmias (VAs).
A phase 3 trial shows lumateperone as adjunctive therapy with antidepressants significantly reduces depression symptoms in patients with major depressive disorder.
New study reveals alarming increase in chronic hypertension among pregnant patients in the last two decades, with no significant impact from updated treatment
These data resulted from a new meta-analysis in which biologic therapies were shown to be less effective among psoriasis patients with clinical characteristics such as age and BMI.
A Seattle-based UW Medicine heart failure program is keeping patients out of the hospital and providing indefinite care for vulnerable heart failure patients.
Data showed a significant reduction in pain for patients with psoriatic arthritis and inadequate response to TNF treated with guselkumab compared with placebo.
In this week's View, Dr. Eagle looks at secular trends of incidence and outcomes in severe aortic stenosis. He then examines titration of medications after acute heart failure.
Nature Reviews Cardiology, Published online: 19 June 2024; doi:10.1038/s41569-024-01054-6 In this Tools of the Trade article, Jablonska describes the use of proximity-based labelling for the proteomic profiling of novel protein–protein interactions.
In this video segment, Palak and Trivedi discuss strategies for improving the management of patients in real-world settings given recent advances in therapies and pathophysiology.
What is the relationship between office and ambulatory blood pressure (BP) measurements as well as different hypertension phenotypes with mortality in a large cohort of patients in primary care?
Treatment with guselkumab led to rapid, clinically meaningful improvements in disease activity among patients with severe psoriatic arthritis, which were maintained through 2 years.
The U.S. Food and Drug Administration (FDA) announced on June 13 that Teleflex/Arrow International are recalling the Arrow FiberOptix Intra-Aortic Balloon (IAB) Catheter Kit and the Arrow UltraFlex IAB Catheter Kits due to a manufacturing issue that may cause the catheter's balloon to become overtwisted, preventing full balloon inflation and resulting in patient harm.
In this interview, Andrew Choi, MD, FACC and Clyde W. Yancy, MD, MSc, MACC discuss insights from data and studies involving plaque burden, morphology and flow.
Triglyceride glucose (TyG) index and its related parameters have been introduced as cost-effective surrogate indicators of insulin resistance, while prospective evidence of their effects on atherosclerotic car.
Findings suggest patients with AATD with liver and/or lung disease face greater all-cause costs and healthcare resource utilization than those with AATD alone.
Perioperative management and cardiac surgery in pregnant women with anti-phospholipid syndrome combined with heart valve disease have been rarely reported.
Nature Reviews Cardiology, Published online: 19 June 2024; doi:10.1038/s41569-024-01055-5 In this Tools of the Trade article, Berkeley and Thomson describe the use of a minimally invasive strategy to standardize the induction of myocardial infarction in mice.
Background Neurocardiogenic syncope is a common condition with significant associated psychological and physical morbidity. The effectiveness of therapeutic options for neurocardiogenic syncope beyond placebo remains uncertain. Methods The primary endpoint was the risk ratio (RR) of spontaneously recurring syncope following any therapeutic intervention.
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