Wed.Oct 18, 2023

article thumbnail

Four patients with chest pain and ‘normal’ ECG: can you trust the computer interpretation?

Dr. Smith's ECG Blog

Written by Jesse McLaren Four patients presented with chest pain. All initial ECGs were labeled ‘normal’ or ‘otherwise normal’ by the computer interpretation, and below are the ECGs with the final cardiology interpretation. If you were working in a busy emergency department, would you like to be interrupted to interpret these ECGs or can these patients safely wait to be seen because of the normal computer interpretation?

article thumbnail

Hemostasis after transradial coronary intervention by rotary compression device with sterile gauze is associated with more adverse events: a retrospective study

Coronary Artery Disease Journal

Objective We investigated the relationship between using a rotary compression device (RCD) with or without sterile gauze and adverse events in transradial access (TRA) for coronary intervention. Methods In this study involving 933 patients at Yueyang Hospital, we recorded TRA-related adverse events, such as bleeding, forearm hematoma, swollen palms, radial artery occlusion (RAO) and others.

article thumbnail

A 20-something woman with cardiac arrest.

Dr. Smith's ECG Blog

The patient is a 20 something female. She is healthy with no known cardiac disease. She was admitted to the neurology department due to headache and vomiting. She was found to have a viral CNS infection. A few days into her hospital stay she developed chest discomfort and the following ECG was recorded. What do you think? Why such large T-waves? Are these hyperacute T-waves?

article thumbnail

Remote Ischemic Conditioning and Outcomes in Acute Ischemic Stroke With Versus Without Large Artery Atherosclerosis

Stroke Journal

Stroke, Volume 54, Issue 12 , Page 3165-3168, December 1, 2023. BACKGROUND:RICAMIS trial (The Remote Ischemic Conditioning for Acute Moderate Ischemic Stroke) has demonstrated efficacy of remote ischemic conditioning (RIC) in acute ischemic stroke. We conducted a post hoc analysis of RICAMIS to investigate whether large artery atherosclerosis (LAA) subtype contributed to the outcomes.METHODS:This is a post hoc analysis of the RICAMIS trial.

article thumbnail

Converting brain immune cells into neurons helps mice recover after stroke

Science Daily - Stroke

Researchers have discovered that turning brain immune cells into neurons successfully restores brain function after stroke-like injury in mice. These findings suggest that replenishing neurons from immune cells could be a promising avenue for treating stroke in humans.

Stroke 40
article thumbnail

AI can identify people with abnormal heart rhythms

Science Daily - Heart Disease

Investigators found that an artificial intelligence (AI) algorithm can detect an abnormal heart rhythm in people not yet showing symptoms. The algorithm, which identified hidden signals in common medical diagnostic testing, may help doctors better prevent strokes and other cardiovascular complications in people with atrial fibrillation -- the most common type of heart rhythm disorder.

article thumbnail

Direct-Wire Electrocautery – a Novel Technique to Facilitate Transseptal Access in Cryoablation

HeartRhythm

Pulmonary vein isolation (PVI) is increasingly utilized for the treatment of atrial fibrillation (AF).1 One method of achieving PVI is cryoablation, which has demonstrated comparable success to radiofrequency ablation, but does present unique challenges.

More Trending

article thumbnail

Longitudinal mapping of the bidirectional relationship between atrial fibrillation and cardiac remodeling.

HeartRhythm

“Atrial fibrillation begets atrial fibrillation” describes the experimental observation, that artificial maintenance of atrial fibrillation (AF) leads to a marked shortening of atrial effective refractory period, and increase in inducibility and stability of AF, which is completely reversible within one week of sinus rhythm (1). In addition to these electrophysiological and reversible changes, which occur relatively early during AF, AF has been shown to be also associated with cardiac structural

article thumbnail

Facilitating Harmonization of Variables in Framingham, MESA, ARIC, and REGARDS Studies Through a Metadata Repository

Circulation: Cardiovascular Quality & Outcomes

Circulation: Cardiovascular Quality and Outcomes, Volume 16, Issue 11 , Page e009938, November 1, 2023. BACKGROUND:High-quality research in cardiovascular prevention, as in other fields, requires inclusion of a broad range of data sets from different sources. Integrating and harmonizing different data sources are essential to increase generalizability, sample size, and representation of understudied populations—strengthening the evidence for the scientific questions being addressed.METHODS:Here,

article thumbnail

Efficacy, Safety, and Tolerability of Inclisiran in Patients With Homozygous Familial Hypercholesterolemia: Results From the ORION-5 Randomized Clinical Trial

Circulation

Circulation, Ahead of Print. BACKGROUND:Homozygous familial hypercholesterolemia is a genetic disease characterized by extremely high levels of low-density lipoprotein cholesterol (LDL-C) and a high risk of premature cardiovascular events. Phase 2 of ORION (A Study of Inclisiran in Participants With Homozygous Familial Hypercholesterolemia) showed that inclisiran, a small interfering RNA that prevents production of the hepatic PCSK9 protein (proprotein convertase subtilisin/kexin type 9), could

article thumbnail

Previous Ischemic Stroke Significantly Alters Stroke Risk in Newly Diagnosed Cancer Patients

Stroke Journal

Stroke, Volume 54, Issue 12 , Page 3064-3073, December 1, 2023. BACKGROUND:Previous ischemic stroke (IS) is a risk factor for subsequent IS in the general population; it is unclear if this relationship remains true in patients with cancer. Our objective was to examine the association between previous IS and risk for future IS in individuals newly diagnosed with cancer.METHODS:We conducted a retrospective population-based matched cohort study of newly diagnosed adult cancer patients (excluding no

Cancer 40
article thumbnail

Rivaroxaban Plus Aspirin Versus Aspirin Alone After Endovascular Revascularization for Symptomatic PAD: Insights From VOYAGER PAD

Circulation

Circulation, Volume 148, Issue 24 , Page 1919-1928, December 12, 2023. BACKGROUND:Rivaroxaban plus aspirin compared with aspirin alone reduced major cardiac and ischemic limb events after lower extremity revascularization (LER) in the VOYAGER PAD (Vascular Outcomes Study of ASA Along With Rivaroxaban in Endovascular or Surgical Limb Revascularization for Peripheral Artery Disease) trial.

article thumbnail

Effect of Menopause Status on Brain Perfusion Hemodynamics

Stroke Journal

Stroke, Ahead of Print. BACKGROUND:The menopause transition is associated with an increasing risk of cerebrovascular disorders. However, the direct effect of menopause status on brain perfusion hemodynamics remains unclear. This study aimed to explore the influence of menopause status on cerebral blood flow (CBF) using arterial spin labeling magnetic resonance imaging.METHODS:In this cross-sectional study, 185 subjects underwent arterial spin labeling magnetic resonance imaging at a hospital in