Thu.Mar 27, 2025

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Comparison of multiple arterial grafts vs. single arterial graft in coronary artery bypass surgery: a systematic review and meta-analysis

Frontiers in Cardiovascular Medicine

Observational studies and randomised controlled trials (RCTs) have yielded conflicting results regarding the outcomes of multiple arterial grafts (MAG) vs. single arterial grafts (SAG) in coronary artery bypass graft (CABG) surgery. We conducted a comprehensive search across multiple databases for RCTs that directly compared MAG and SAG. The clinical outcomes assessed included all-cause mortality, cardiac-specific mortality, myocardial infarction (MI), repeat revascularization, stroke, sternal w

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Navigating Biologic Treatment Selection in Psoriasis and Psoriatic Arthritis

HCPLive

Panelists discuss how selecting among the numerous approved biologic therapies for psoriasis requires a personalized approach that weighs factors such as efficacy data, safety profiles, comorbidities, insurance coverage, and administration preferences, with patient preferences playing a crucial role in the decision-making process, as involving patients in treatment selection enhances medication adherence and satisfaction and ultimately improves long-term outcomes.

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Scientific journey from PSCK9 discovery in familial hypercholesterolaemia

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 28 March 2025; doi:10.1038/s41569-025-01147-w Countries globally face major challenges in the early diagnosis and treatment of hypercholesterolaemia and cardiovascular disease, with numerous health inequities by geography and income. Perseverance, hard work, integrity and commitment can transform aspiration into reality.

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Abbott Receives CE Mark for Pulsed Field Ablation System

DAIC

tim.hodson Thu, 03/27/2025 - 12:18 March 27, 2025 Abbott recently announced it has received CE Mark in Europe for the Volt PFA System to treat patients battling atrial fibrillation (AFib). With the earlier-than-expected CE Mark, Abbott has begun commercial PFA cases in the EU with physicians who have already gained experience with the Volt PFA System within Abbott's PFA clinical studies.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Key Takeaways and Considerations for the Use of BTK Inhibitors in CSU Treatment

HCPLive

Panelists discuss how Bruton tyrosine kinase (BTK) inhibitors represent a promising new therapeutic class for chronic spontaneous urticaria (CSU) by offering rapid symptom control through targeted inhibition of both mast cell and B cell pathways, with newer agents like remibrutinib showing high selectivity, favorable safety, and robust efficacy in clinical trials that could position them as an important oral therapy option between antihistamines and biologics.

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GE Healthcare Launches New Cardiac PET tracer

DAIC

tim.hodson Thu, 03/27/2025 - 15:40 March 27, 2025 GE HealthCare is announcing theU.S.launch of Flyrcado(flurpiridaz F 18) injection at the 2025American College of Cardiology(ACC) AnnualScientific Session & Expo inChicago. Flyrcado is aunit dose positron emission tomography myocardial perfusion imaging (PET MPI) agent. In 2024, the FDA approved Flyrcado for patients with known or suspected coronary artery disease (CAD), delivering higher diagnostic efficacy compared to single-photon emission com

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Deadline Extended for Submissions to the AI in Cardiovascular Health Collection!

International Journal of Cardiovascular Sciences

The International Journal of Cardiovascular Sciences has extended the deadline for article submissions to the special issue on Artificial Intelligence in Cardiovascular Health until August 30, 2025 ! Publications in this collection will continue until December 2025. Brazilian and international researchers are invited to submit their work for this special issue, edited by Drs.

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Anticipating Fitusiran’s Approval for Factor-Agnostic Hemophilia A, B, with Robert F. Sidonio Jr., MD, MSc

HCPLive

Sidonio discussed how fitusiran may improve the treatment landscape and reduce treatment burden for people with hemophilia A or B with or without inhibitors.

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Women's health: an imAging-based cardiovascular risK-rEdUction Program (WAKE UP) study. Rationale and design

Frontiers in Cardiovascular Medicine

BackgroundCardiovascular (CV) disease is the leading cause of death in women. Although 80% of CV disease events can be prevented, mortality is projected to increase, particularly in young women.ObjectivesTo promote CV health in women and encourage appropriate lifestyle changes by increasing awareness through vascular ultrasound imaging.MethodsWAKE UP is a prospective case-control study in a target population of 720 asymptomatic women, aged 4070 years with 1 major CV risk factor (RF).

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What balance could mean for heart and brain health

Medical Xpress - Cardiology

It's an ability and skill often taken for granted. It affects quality of life and has been linked to heart disease and stroke. As we age and our muscles weaken, balance becomes crucial to staying active and supporting a healthy heart and brain.

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An Athlete’s Triumph Overcoming Thoracic Outlet Syndrome

CTVS

For Michael Miskovich, an active 25-year-old, fitness is more than a hobby, it is his way of life. From mixed martial arts (MMA) and kickboxing to rigorous weightlifting, he pushes his body to the limit. But in December 2024, a slight shoulder tightness quickly took a serious turn, revealing a blood clot and a Thoracic Outlet Syndrome diagnosis.

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Elevating global heart failure care with new certification

American Heart News - Heart News

DALLAS, March 27, 2025 More than 56 million people globally live with heart failure (HF), which prevents the body from getting enough of the oxygen-rich blood it needs to work properly.[1] While there is no cure for HF, many people with this.

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Will this case be flagged for Quality Improvement in the STEMI/NSTEMI Paradigm?

Dr. Smith's ECG Blog

Written by Jesse McLaren A 40 year old presented with 90 minutes of midsternal chest pressure, radiating to bilateral arms, with shortness of breath. Below is the first ECG, signed off by the over-reading cardiologist agreeing with the computer interpretation: ST elevation, consider early repolarization, pericarditis, or injury. What do you think? What do you think?

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What is vascular dementia? A neurologist explains

Medical Xpress - Cardiology

An estimated 55 million people are believed to be living with dementia, according to health officials. Vascular diseases contribute to approximately 25% of all diagnoses.

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Organophosphate Pesticide Exposure Linked to Atopic Dermatitis Risk

HCPLive

These data point to the role of environmental factors in the development of atopic dermatitis and indicate targeted prevention strategies for those known to be impacted.

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Thrombectomy for MeVO and DVO: The End of the Road or Just a Detour?

Stroke: Vascular and Interventional Neurology

Stroke: Vascular and Interventional Neurology, Ahead of Print.

Strokes 74
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Distinguishing Drug-Induced vs Classic Autoimmune Hepatitis, with Lily Dara, MD

HCPLive

Dara explains the importance of distinguishing DI-ALH from classic AIH, how their management differs, and where research in this field is heading.

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Unveiling the hidden risk: a case of severe jaundice triggered by intra-aortic balloon pump after cardiac surgery

Journal of Cardiothoracic Surgery

The Intra-Aortic Balloon Pump (IABP) is a widely utilized technique to provide circulatory support for critically ill patients with cardiac dysfunction. While IABP therapy offers clinical benefits, the placeme.

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ACC 2025: 7 Trials to Watch

HCPLive

A look at 7 phase 2 and phase 3 trials with significant implications from ACC 2025's late-breaking and featured clinical research sessions.

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The role of left atrio-ventricular coupling index and left atrial ejection fraction in predicting onset of atrial fibrillation and adverse cardiac events in hypertrophic cardiomyopathy

Cardiovascular Ultrasound

Several predictors of atrial fibrillation (AF) onset in patients with hypertrophic cardiomyopathy (HCM) have been proposed, however, all of them showed limited accuracy. This study aims to assess the role of n.

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Omalizumab Enhances Oral Immunotherapy for Pediatric Food Allergies

HCPLive

A study found omalizumab enables faster, safer desensitization in children with food allergies, improving oral immunotherapy outcomes and reducing reactions.

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Pericoronary adipose tissue attenuation predicts compositional plaque changes: a 12-month longitudinal study in individuals with type 2 diabetes without symptoms or known coronary artery disease

Cardiovascular Diabetology

Pericoronary adipose tissue attenuation (PCATa), derived from coronary computed tomography angiography (CCTA), is a novel marker of inflammation in the coronary arteries. Patients with type 2 diabetes mellitus.

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Allegheny General Hospital First in Western PA to Participate in Clinical Trial Using Artificial Intelligence to Detect Deep Vein Thrombosis in Cardiac Patients

HCPLive

The AI-powered trial was officially initiated in January 2025.

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Heart rate variability tests for diagnosing cardiovascular autonomic neuropathy in patients with type 2 diabetes mellitus in advanced stages of kidney disease

Cardiovascular Diabetology

Cardiovascular Autonomic Neuropathy (CAN) is one of the most devastating complications of Diabetes Mellitus (DM) and presents high morbidity and mortality. Its association with diabetic kidney disease (DKD) wo.

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Severity of Transient Shedding with Minoxidil for Alopecia Linked to Treatment Efficacy

HCPLive

In this analysis, the investigators evaluated the temporal increase in hair shedding amounts following topical minoxidil utilization.

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New Frontiers at ACC Meeting: Semaglutide, INOCA, & More

Med Page Today

(MedPage Today) -- CHICAGO -- Coming this weekend, the American College of Cardiology (ACC) annual conference will feature research exploring new frontiers for GLP-1 drugs in cardiovascular medicine, and foundational answers are expected for.

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Meta-Analysis Confirms the Unlikelihood of GLP-1 RA Raising Suicidal Risk

HCPLive

A meta-analysis of 27 trials found no increased risk of suicide or self-harm with GLP-1 RAs, supporting their safety for diabetes and obesity management.

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Hypertension causes kidney changes at an early stage, finds study

Medical Xpress - Cardiology

A research team from the Medical University of Vienna has investigated structural changes in kidneys of patients with hypertension and type 2 diabetes. The results show that high blood pressure can lead to abnormalities in the podocytes, specialized cells in the renal filter, even without other pre-existing conditions such as diabetes.

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Pretransplant Immunotherapy for Hepatocellular Carcinoma, with Parissa Tabrizian, MD

HCPLive

Tabrizian discusses neoadjuvant immunotherapy for HCC, describing its success in the adjuvant setting but uncertainties about its use before transplant.

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A caffeine kick can come with health risks

Medical Xpress - Cardiology

Caffeine is almost ubiquitous in everyday life. It is found in the typical morning cup of coffee, in black tea, in cola, in energy drinks and even in chocolate.

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Prior Oral Anticoagulant Use May Influence Stroke, Bleeding Risk in AF

HCPLive

OAC-naive patients experienced a significantly smaller increase in stroke or systemic embolism with asundexian than apixaban.

Strokes 52
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Burden of Multimorbidity in Young Women With ST‐Segment–Elevation Myocardial Infarction

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print.

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The Need for Hepatitis Vaccination in Chronic Liver Disease, with Paul Kwo, MD

HCPLive

Kwo explains why hepatitis A and B vaccination is important for people with liver disease and reviews different vaccine options.

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Association Between Short‐Term Change in Quality of Life and Clinical Outcomes: A Post Hoc Analysis of the ISCHEMIA Trial

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print.

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KDIGO Announces Publication of 2025 ADPKD Guideline

HCPLive

The new guideline provides healthcare providers, people living with ADPKD, and stakeholders with practical tools to improve diagnosis, care, and treatment.

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Understanding Reasons for Oral Anticoagulation Nonprescription in Atrial Fibrillation Using Large Language Models

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. BackgroundRates of oral anticoagulation (OAC) nonprescription in atrial fibrillation approach50%. Understanding reasons for OAC nonprescription may reduce gaps in guidelinerecommended care. We aimed to identify reasons for OAC nonprescription from clinical notes using large language models.MethodsWe identified all patients and associated clinical notes in our health care system with a clinicianbilled visit for atrial fibrillation without