Mon.May 20, 2024

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Significant gaps between science of obesity and the care patients receive

American Heart News - Heart News

Statement Highlights: More than 40% of adults in the United States live with obesity, and the percentage of people living with obesity continues to increase dramatically. While experts have learned a great deal about the causes of obesity and.

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Study finds fat cells influence heart health in Chagas disease

Medical Xpress - Cardiology

Jyothi Nagajyothi, Ph.D. and her laboratory at the Hackensack Meridian Center for Discovery and Innovation (CDI) have identified what may be the main mechanism for how chronic Chagas disease, a parasitic infection affecting millions of people worldwide, can cause irreversible and potentially fatal heart damage.

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An undergraduate who is an EKG tech sees something. The computer calls it completely normal. How about the physicians?

Dr. Smith's ECG Blog

This was sent by an undergraduate (not yet in medical school, but applying now) who works as an ED technician (records all EKGs, helps with procedures, takes vital signs) and who reads this blog regularly. Edited by Smith He also sent me this great case. A 63 year old man with a history of hypertension, hyperlipidemia, prediabetes, and a family history of CAD developed chest pain, shortness of breath, and diaphoresis after consuming a large meal at noon.

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Finerenone Treatment Slows Chronic Kidney Disease Progression After Heart Failure Hospitalization

HCPLive

A numerically slower decline in eGFR was reported in the finerenone cohort after hospitalization for heart failure when compared with placebo.

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How are asthma and heart health linked?

Medical Xpress - Cardiology

Although the heart and lungs are neighbors in your chest, people may think of them as separate entities with unrelated problems.

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Artificially transplanted mitochondria in endothelial cells promote mitophagy

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 21 May 2024; doi:10.1038/s41569-024-01041-x A study in Nature describes a single-cell-type strategy for vascular cell therapies that involves the artificial transplantation of mitochondria to endothelial cells, which promotes mitophagy and facilitates the formation of functional vessels in ischaemic tissue without the need for mesenchymal stromal cell support.

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Study finds good clinical outcomes for over 30% of ischemic stroke patients receiving endovascular treatment

Medical Xpress - Cardiology

Endovascular treatment for acute ischemic stroke patients beyond six hours from onset is still effective, according to a collaborative study conducted by the LKS Faculty of Medicine at the University of Hong Kong (HKUMed) and Queen Mary Hospital (QMH). The study, conducted over five years, found that over 30% of patients who received endovascular treatment had a good clinical outcome even after six hours of the onset of symptoms.

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PROTECT Drugs Tied to Slower eGFR Decline vs Standard Care in IgA Nephropathy

Med Page Today

(MedPage Today) -- LONG BEACH, Calif. -- Both sparsentan (Filspari) and irbesartan were associated with significantly slower estimated glomerular filtration rate (eGFR) decline compared with standard of care in patients with immunoglobulin A.

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Michael Dolinger, MD: Recognizing Intestinal Ultrasound’s Potential in Ulcerative Colitis

HCPLive

Dolinger reviews findings from his research presented at DDW about the use of intestinal ultrasound response for predicting endoscopic outcomes in children with UC.

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Leadless Pacing Wirelessly Linked to Subcutaneous Defibrillator Hits Targets for ATP

Med Page Today

(MedPage Today) -- BOSTON -- A leadless pacemaker reliably communicated with a subcutaneous implantable cardioverter-defibrillator (S-ICD) to deliver anti-tachycardia (ATP) and bradycardia pacing, the MODULAR ATP study showed. In terms of safety.

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Implementation of Obesity Science Into Clinical Practice: A Scientific Statement From the American Heart Association

Circulation

Circulation, Ahead of Print. Obesity is a recognized public health epidemic with a prevalence that continues to increase dramatically in nearly all populations, impeding progress in reducing incidence rates of cardiovascular disease. Over the past decade, obesity science has evolved to improve knowledge of its multifactorial causes, identifying important biological causes and sociological determinants of obesity.

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Aaron Henry, PA-C, MSHS: Regaining Black Male Patient Trust in the Doctor's Office

HCPLive

Black men face significantly worse health outcomes in the US. Henry explains why the clinician needs to focus on building more authentic trust in their interactions.

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Simple Changes. Big Results.

Dr. Paddy Barrett

This slide highlights one of the most important studies in cardiovascular medicine. Let’s break it down. In simple terms it shows that if you get the basics right when you are young your future risk of heart disease is massively reduced. If you get 7 core factors right your risk of dying from heart disease over a 32 year time frame drops by 93%.

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8 in 8 Series: Latin Heart Rounds on Mitral Annular Disjunction

Society of Thoracic Surgeons - Congenital

Video 8 in 8 Series: Latin Heart Rounds on Mitral Annular Disjunction kchalko Mon, 05/20/2024 - 08:24 In this 8x8 video (presented in Spanish), Dr. Juan Crestanello, chief of cardiac surgery at Mayo Clinic in Rochester, MN, discusses annular disjunction of the mitral valve, its medical and surgical implications, and also the operative techniques used to deal with this anatomical feature.

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Oriana Damas, MD: Intervals of a Low-Calorie, Plant-Based Diet Show Promise for UC

HCPLive

Damas explains key findings from her pilot study exploring intervals of a low-calorie plant-based diet as adjunctive therapy to medication in patients with ulcerative colitis.

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Transcatheter-Based Interventions for Tetralogy of Fallot: Key Points

American College of Cardiology

The following are key points to remember from a state-of-the-art review on transcatheter-based interventions for tetralogy of Fallot (TOF) across all age groups:

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Guselkumab Achieves Clinical, Endoscopic Remission in Ulcerative Colitis

HCPLive

The phase 3 QUASAR Maintenace study met its primary endpoint of clinical remission and demonstrated statistically significant endoscopic remission rates in UC treatment.

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Comparative Outcomes of Empagliflozin to Dapagliflozin in HF Patients

American College of Cardiology

Are there differences between empagliflozin and dapagliflozin for the composite outcome of all-cause mortality and hospitalization in patients with heart failure (HF)?

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Opioid Prescriptions Nearly 3 Times More Likely in Patients with Rheumatic, Autoimmune Diseases

HCPLive

Patients with systemic autoimmune/inflammatory rheumatic diseases were nearly 3 times more likely to receive opioid prescriptions from 2006 to 2019.

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Four Might Be the Magic Number for Anticoagulation of Subclinical Afib

Med Page Today

(MedPage Today) -- BOSTON -- In deciding on anticoagulation with apixaban (Eliquis) for patients with device-detected, subclinical atrial fibrillation (SCAF), one key number appeared to distinguish those for whom the benefit would outweigh the.

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Solutions to Prevent Climate Change-Related Illness, with Janelle Bludhorn, PA-C

HCPLive

Bludhorn reviews preventive measures and strategic collaboration to ensure high-risk patients for conditions like heat stroke are identified before an acute event occurs.

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Discordance Among ApoB, non–HDL-C, and Triglycerides for CV Prevention

American College of Cardiology

Does apolipoprotein B (apoB) have a utility in atherosclerotic cardiovascular disease (ASCVD) or are low-density lipoprotein cholesterol (LDL-C), non–high-density lipoprotein cholesterol (non–HDL-C), and triglycerides sufficient for routine cardiovascular (CV) care?

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How to Adequately Screen for and Treat Cognitive Decline in Primary Care

HCPLive

James R. Kilgore, DMSc, PhD, PA-C, discusses a new primary care screening tool for cognitive decline, plus lifestyle interventions that may complement drugs.

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Managing CIED TLE For TTVR Focus of State-of-the-Art Review

American College of Cardiology

A multidisciplinary care team (MDT) must balance the risks and benefits of transvenous lead extraction (TLE) vs. entrapping leads in patients with preexisting leads from cardiac implantable electronic device (CIED) being considered for orthotopic transcatheter tricuspid valve replacement (TTVR), which accounts for roughly 35% of the TTVR population, according to a JACC State-of-the-Art Review, published May 13.

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Ali Rezaie, MD: Trends in GLP-1RA use Among Nondiabetic, Nonobese Patients

HCPLive

Rezaie describes recent trends in GLP-1RA prescription patterns from his population-based research presented at DDW, highlighting increases in off-label use.

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Andexanet yields better control of hematoma expansion than usual care, finds study

Medical Xpress - Cardiology

For patients who had taken factor Xa inhibitors within 15 hours before having an acute intracerebral hemorrhage, andexanet alfa, which reverses the effects of factor Xa inhibitors, results in better control of hematoma expansion than usual care, according to a study published in the New England Journal of Medicine.

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Depression Screening: Challenges and Solutions at the Primary Care Level

HCPLive

Beth Browning, PA-C, LPC, provides advice for busy primary care providers to efficiently incorporate timely and treatment-initiating depression screening.

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Do patients with device-detected atrial fibrillation and prior stroke benefit from anticoagulation?

Medical Xpress - Cardiology

In patients with device-detected atrial fibrillation and a prior stroke, oral anticoagulation increases bleeding without a clear reduction in stroke. This finding was presented by Prof. Paulus Kirchhof, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany, in a late-breaking clinical trials session at the annual congress of the American Heart Rhythm Society (HRS 2024) held in Boston, U.S., May 16–19.

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Toby Maher, MD, PhD: Improving Lung Function with ENV-101 Treatment of Idiopathic Pulmonary Fibrosis

HCPLive

These late-breaking data on drug candidate ENV-101 were presented at ATS 2024 and resulted from a new study on the drug’s effect on individuals with IPF.

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Beta-Blocker Fails to Prevent COPD Exacerbations

Med Page Today

(MedPage Today) -- SAN DIEGO -- The beta-blocker bisoprolol did not improve exacerbations in chronic obstructive pulmonary disease (COPD) patients, a randomized clinical trial found. Exacerbations requiring antibiotics, oral corticosteroids.

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Kyle Fortman, PA-C, MBA: Troponin and Heart Injury Risk Screening Recommendations

HCPLive

An AAPA 2024 session reflected on the joint AHA/ACC chest pain guidelines, particularly the adoption of high-density troponin level testing since 2021.

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Early CRT Benefits HF With Moderately Reduced Ejection Fraction

Med Page Today

(MedPage Today) -- BOSTON -- Early cardiac resynchronization therapy (CRT) benefited patients with moderately reduced ejection fraction (EF) and left bundle branch block (LBBB) but no indication for pacing, according to trial findings that suggested.

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Study Suggests Epidermolysis Bullosa Improved with CBD Topical Cream Treatment

HCPLive

More than half of patients recruited for this research showed improvements in wound healing, and a significant number had greater wound stability.

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8 in 8 Series: Latin Heart Rounds on Mitral Annual Disjunction

Society of Thoracic Surgeons - Congenital

Video 8 in 8 Series: Latin Heart Rounds on Mitral Annual Disjunction kchalko Mon, 05/20/2024 - 08:24 In this 8x8 video (presented in Spanish), Dr. Juan Crestanello, chief of cardiac surgery at Mayo Clinic in Rochester, MN, discusses annular disjunction of the mitral valve, its medical and surgical implications, and also the operative techniques used to deal with this anatomical feature.

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Approaching Treatment in Hypercortisolism

HCPLive

Panelists review current guidelines for treating hypercortisolism, noting the need for guidelines to align with recent advancements, and share their own clinical practice approaches.

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Geisinger Enrolls First Patient in Amyloid Cardiomyopathy Trial

DAIC

milla1cf Mon, 05/20/2024 - 07:00 May 20, 2024 — Cardiologist Brendan Carry, MD , and a team of Geisinger physicians have enrolled the first patient in the U.S. into a cardiac amyloidosis trial. The team is also the first to in the U.S. to screen for the trial. “If a patient qualifies for the clinical trial, it will allow us to provide a treatment option when they receive an amyloidosis diagnosis without having to travel outside of the region for care,” said Dr.

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Comparing pressure-bounded versus thermodilution-derived coronary flow reserve in unobstructed coronary arteries

The American Journal of Cardiology

Publication date: Available online 19 May 2024 Source: The American Journal of Cardiology Author(s): Daniel T.Y. Ang, George Abraham, Krystalina Y.T. Sim, Novalia P. Sidik, Majid Anwar, Thomas J. Ford, Colin Berry, Stephen P.

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