Mon.May 20, 2024

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Study finds fat cells influence heart health in Chagas disease

Medical Xpress - Cardiology

Jyothi Nagajyothi, Ph.D. and her laboratory at the Hackensack Meridian Center for Discovery and Innovation (CDI) have identified what may be the main mechanism for how chronic Chagas disease, a parasitic infection affecting millions of people worldwide, can cause irreversible and potentially fatal heart damage.

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An undergraduate who is an EKG tech sees something. The computer calls it completely normal. How about the physicians?

Dr. Smith's ECG Blog

This was sent by an undergraduate (not yet in medical school, but applying now) who works as an ED technician (records all EKGs, helps with procedures, takes vital signs) and who reads this blog regularly. Edited by Smith He also sent me this great case. A 63 year old man with a history of hypertension, hyperlipidemia, prediabetes, and a family history of CAD developed chest pain, shortness of breath, and diaphoresis after consuming a large meal at noon.

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How are asthma and heart health linked?

Medical Xpress - Cardiology

Although the heart and lungs are neighbors in your chest, people may think of them as separate entities with unrelated problems.

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Significant gaps between science of obesity and the care patients receive

American Heart News - Heart News

Statement Highlights: More than 40% of adults in the United States live with obesity, and the percentage of people living with obesity continues to increase dramatically. While experts have learned a great deal about the causes of obesity and.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Finerenone Treatment Slows Chronic Kidney Disease Progression After Heart Failure Hospitalization

HCPLive

A numerically slower decline in eGFR was reported in the finerenone cohort after hospitalization for heart failure when compared with placebo.

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PROTECT Drugs Tied to Slower eGFR Decline vs Standard Care in IgA Nephropathy

Med Page Today

(MedPage Today) -- LONG BEACH, Calif. -- Both sparsentan (Filspari) and irbesartan were associated with significantly slower estimated glomerular filtration rate (eGFR) decline compared with standard of care in patients with immunoglobulin A.

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Artificially transplanted mitochondria in endothelial cells promote mitophagy

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 21 May 2024; doi:10.1038/s41569-024-01041-x A study in Nature describes a single-cell-type strategy for vascular cell therapies that involves the artificial transplantation of mitochondria to endothelial cells, which promotes mitophagy and facilitates the formation of functional vessels in ischaemic tissue without the need for mesenchymal stromal cell support.

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Ochsner Medical Center-Baton Rouge earns Acute Stroke Ready Certification from Joint Commission

DAIC

milla1cf Mon, 05/20/2024 - 08:00 May 20, 2024 — Ochsner Medical Center - Baton Rouge has earned The Joint Commission’s Gold Seal of Approval and the American Stroke Association’s Heart-Check mark for Acute Stroke Ready Certification. The designation means OMC-Baton Rouge meets The Joint Commission's designation for readiness to treat patients who experience severe stroke.

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Leadless Pacing Wirelessly Linked to Subcutaneous Defibrillator Hits Targets for ATP

Med Page Today

(MedPage Today) -- BOSTON -- A leadless pacemaker reliably communicated with a subcutaneous implantable cardioverter-defibrillator (S-ICD) to deliver anti-tachycardia (ATP) and bradycardia pacing, the MODULAR ATP study showed. In terms of safety.

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Simple Changes. Big Results.

Dr. Paddy Barrett

This slide highlights one of the most important studies in cardiovascular medicine. Let’s break it down. In simple terms it shows that if you get the basics right when you are young your future risk of heart disease is massively reduced. If you get 7 core factors right your risk of dying from heart disease over a 32 year time frame drops by 93%.

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Aaron Henry, PA-C, MSHS: Regaining Black Male Patient Trust in the Doctor's Office

HCPLive

Black men face significantly worse health outcomes in the US. Henry explains why the clinician needs to focus on building more authentic trust in their interactions.

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Implementation of Obesity Science Into Clinical Practice: A Scientific Statement From the American Heart Association

Circulation

Circulation, Ahead of Print. Obesity is a recognized public health epidemic with a prevalence that continues to increase dramatically in nearly all populations, impeding progress in reducing incidence rates of cardiovascular disease. Over the past decade, obesity science has evolved to improve knowledge of its multifactorial causes, identifying important biological causes and sociological determinants of obesity.

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Michael Dolinger, MD: Recognizing Intestinal Ultrasound’s Potential in Ulcerative Colitis

HCPLive

Dolinger reviews findings from his research presented at DDW about the use of intestinal ultrasound response for predicting endoscopic outcomes in children with UC.

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Transcatheter-Based Interventions for Tetralogy of Fallot: Key Points

American College of Cardiology

The following are key points to remember from a state-of-the-art review on transcatheter-based interventions for tetralogy of Fallot (TOF) across all age groups:

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8 in 8 Series: Latin Heart Rounds on Mitral Annular Disjunction

Society of Thoracic Surgeons - Congenital

Video 8 in 8 Series: Latin Heart Rounds on Mitral Annular Disjunction kchalko Mon, 05/20/2024 - 08:24 In this 8x8 video (presented in Spanish), Dr. Juan Crestanello, chief of cardiac surgery at Mayo Clinic in Rochester, MN, discusses annular disjunction of the mitral valve, its medical and surgical implications, and also the operative techniques used to deal with this anatomical feature.

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Opioid Prescriptions Nearly 3 Times More Likely in Patients with Rheumatic, Autoimmune Diseases

HCPLive

Patients with systemic autoimmune/inflammatory rheumatic diseases were nearly 3 times more likely to receive opioid prescriptions from 2006 to 2019.

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Comparative Outcomes of Empagliflozin to Dapagliflozin in HF Patients

American College of Cardiology

Are there differences between empagliflozin and dapagliflozin for the composite outcome of all-cause mortality and hospitalization in patients with heart failure (HF)?

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Oriana Damas, MD: Intervals of a Low-Calorie, Plant-Based Diet Show Promise for UC

HCPLive

Damas explains key findings from her pilot study exploring intervals of a low-calorie plant-based diet as adjunctive therapy to medication in patients with ulcerative colitis.

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Small Left Ventricle in AF Patients and Increased CV Risk

American College of Cardiology

What is the association between small left ventricle (LV) and risk of cardiovascular (CV) events in the atrial fibrillation (AF) population?

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Guselkumab Achieves Clinical, Endoscopic Remission in Ulcerative Colitis

HCPLive

The phase 3 QUASAR Maintenace study met its primary endpoint of clinical remission and demonstrated statistically significant endoscopic remission rates in UC treatment.

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Discordance Among ApoB, non–HDL-C, and Triglycerides for CV Prevention

American College of Cardiology

Does apolipoprotein B (apoB) have a utility in atherosclerotic cardiovascular disease (ASCVD) or are low-density lipoprotein cholesterol (LDL-C), non–high-density lipoprotein cholesterol (non–HDL-C), and triglycerides sufficient for routine cardiovascular (CV) care?

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Ethical Concerns for Remote Computer Perception in Cardiology: New Stages for Digital Health Technologies, Artificial Intelligence, and Machine Learning

Circulation: Cardiovascular Quality & Outcomes

Circulation: Cardiovascular Quality and Outcomes, Volume 17, Issue 5 , Page e010717, May 1, 2024.

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Managing CIED TLE For TTVR Focus of State-of-the-Art Review

American College of Cardiology

A multidisciplinary care team (MDT) must balance the risks and benefits of transvenous lead extraction (TLE) vs. entrapping leads in patients with preexisting leads from cardiac implantable electronic device (CIED) being considered for orthotopic transcatheter tricuspid valve replacement (TTVR), which accounts for roughly 35% of the TTVR population, according to a JACC State-of-the-Art Review, published May 13.

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Four Might Be the Magic Number for Anticoagulation of Subclinical Afib

Med Page Today

(MedPage Today) -- BOSTON -- In deciding on anticoagulation with apixaban (Eliquis) for patients with device-detected, subclinical atrial fibrillation (SCAF), one key number appeared to distinguish those for whom the benefit would outweigh the.

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Depressive Symptoms Linked to Higher Risk of Peripheral Arterial Disease

HCPLive

During follow-up, rates of incident PAD were higher among patients with depressive symptoms compared with those without depression.

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NCDR at Heart Rhythm 2024: Pediatric Subcutaneous ICD; Catheter Ablation For Atrial Tachyarrhythmias; More

American College of Cardiology

Several abstracts at Heart Rhythm 2024, held May 16-19 in Boston, MA, featured data from the NCDR suite of registries. Research covered topics such as outcomes for pediatric subcutaneous ICD implantation; procedural success rates and risk factors associated with catheter ablation for atrial tachyarrhythmias; comparing echocardiographic guidance during left atrial appendage occlusion (LAAO); and atrial fibrillation (AFib) ablation in patients with heart failure with reduced ejection fraction (HFr

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Toby Maher, MD, PhD: Improving Lung Function with ENV-101 Treatment of Idiopathic Pulmonary Fibrosis

HCPLive

These late-breaking data on drug candidate ENV-101 were presented at ATS 2024 and resulted from a new study on the drug’s effect on individuals with IPF.

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ACC CardiaCast: Pulse Check: Screening for Psychological Distress

American College of Cardiology

In this episode, host Andrea Price MS, AACC brings together Jamie Jackson, PhD, and David Harrison, MD, to discuss screening for psychological distress (e.g., PHQ-4) and when to refer patients for further evaluation. The importance of identifying psychological distress in cardiovascular medicine is highlighted.

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Depression Screening: Challenges and Solutions at the Primary Care Level

HCPLive

Beth Browning, PA-C, LPC, provides advice for busy primary care providers to efficiently incorporate timely and treatment-initiating depression screening.

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FDA Update: Abbott Recalls HeartMate 3 LVAS Implant Kit

American College of Cardiology

The U.S. Food and Drug Administration (FDA) announced on May 15 that Abbott is recalling the HeartMate 3 Left Ventricular Assist System (LVAS) implant kit due to risk of blood leakage or air entering the seal interface between the left ventricular assist device inflow cannula and the apical cuff.

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How to Adequately Screen for and Treat Cognitive Decline in Primary Care

HCPLive

James R. Kilgore, DMSc, PhD, PA-C, discusses a new primary care screening tool for cognitive decline, plus lifestyle interventions that may complement drugs.

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CathPCI Registry: How Does Operator Career Status Impact PCI Outcomes?

American College of Cardiology

Early-career interventional cardiologists are performing PCI procedures on patients with more acute presentations and higher predicted risk of mortality and bleeding than their more experienced counterparts, which are associated with modestly worse outcomes, according to a study published May 13 in JACC.

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The Impact of GLP-1RA Use in Patients with IBD, with Priya Sehgal, MD, MPH

HCPLive

Sehgal explains the safety and efficacy of GLP-1RAs in patients with IBD as well as the impact on inflammatory biomarkers.

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Andexanet yields better control of hematoma expansion than usual care, finds study

Medical Xpress - Cardiology

For patients who had taken factor Xa inhibitors within 15 hours before having an acute intracerebral hemorrhage, andexanet alfa, which reverses the effects of factor Xa inhibitors, results in better control of hematoma expansion than usual care, according to a study published in the New England Journal of Medicine.

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Ali Rezaie, MD: Trends in GLP-1RA use Among Nondiabetic, Nonobese Patients

HCPLive

Rezaie describes recent trends in GLP-1RA prescription patterns from his population-based research presented at DDW, highlighting increases in off-label use.

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Do patients with device-detected atrial fibrillation and prior stroke benefit from anticoagulation?

Medical Xpress - Cardiology

In patients with device-detected atrial fibrillation and a prior stroke, oral anticoagulation increases bleeding without a clear reduction in stroke. This finding was presented by Prof. Paulus Kirchhof, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany, in a late-breaking clinical trials session at the annual congress of the American Heart Rhythm Society (HRS 2024) held in Boston, U.S., May 16–19.