Nature Reviews - Cardiology

JANUARY 3, 2024

Nature Reviews Cardiology, Published online: 04 January 2024; doi:10.1038/s41569-023-00979-8 In this Review, Sarraju and Nissen summarize the clinical trial evidence for coronary atherosclerotic plaque stabilization and regression with plasma LDL-cholesterol-lowering therapy and other treatments. Invasive and non-invasive imaging modalities used to assess plaque burden and composition are discussed.

Plaque 139

Plaque Cholesterol 139

Medical Xpress - Cardiology

JANUARY 3, 2024

Preeclampsia and other hypertensive disorders of pregnancy—which are characterized by high blood pressure with or without organ dysfunction during the second half of pregnancy—carry considerable short- and long-term risks for both the mother and child. Treatment options (other than expedited delivery) remain limited.

Hypertension 132

Hypertension Circulation Blood Pressure Research 132

HCPLive

JANUARY 3, 2024

Mindfulness-Oriented Recovery Enhancement plus methadone treatment is a promising treatment option for patients with opioid use disorder, having been significantly associated with less return to drug use and methadone treatment dropout, a new study found.

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Medical Xpress - Cardiology

JANUARY 3, 2024

Findings from a published case series research letter by the Henry Ford Health Structural Heart Disease team show that severe mitral stenosis, due to a build-up of calcium deposits in the mitral valve common in elderly patients, can be safely and successfully treated using Intravascular lithotripsy (IVL)-enabled percutaneous balloon mitral valvuloplasty.

Heart Valves 116

Heart Valves Bicuspid/Mitral Stenosis Heart Disease 116

Med Page Today

JANUARY 3, 2024

(MedPage Today) -- It's the season for resolutions -- and the annual "Best Diets" rankings from U.S. News & World Report. For 2024, the Mediterranean diet once again took the top spot for best overall diet. With its emphasis on intake of.

Diet 116

Diet 116

Becker's Hospital Review - Cardiology

JANUARY 3, 2024

Dallas-based UT Southwestern Medical Center researchers found a two-step screening protocol combining clinical risk assessment with biomarker testing that can identify which patients with Type 2 diabetes need medication to prevent heart failure.

Heart Failure 110

Heart Failure Diabetes Biomarkers Research 110

Medical Xpress - Cardiology

JANUARY 3, 2024

The world's first partial heart transplant has achieved what researchers have spent more than a year hoping for—functioning valves and arteries that grow along with the young patient, as hypothesized by the pioneering team behind the procedure at Duke Health.

Heart Transplant 105

Heart Transplant Transplant Research 105

Cardiometabolic Health Congress

JANUARY 3, 2024

In today’s society, the prevalence of obesity has become a significant concern. With sedentary lifestyles and the easy availability of unhealthy food choices, more and more individuals are struggling with weight-related issues. This has led to a growing recognition of the importance of maintaining a healthy weight and taking proactive steps towards achieving it.

Obesity 97

Obesity Diabetes Blood Pressure BMI 97

Frontiers in Cardiovascular Medicine

JANUARY 3, 2024

Patients at each shock stage may behave and present differently with a spectrum of shock severity and adverse outcomes. Shock severity, shock aetiology, and several factors should be integrated in management decision-making. Although the contemporary shock stages classification provided a standardized shock severity assessment, individual agents or management strategy has not yet been studied in the context of each shock stage.

Cardiogenic Shock 90

Cardiogenic Shock Myocardial Infarction Heart Failure Outcomes 90

HCPLive

JANUARY 3, 2024

A case-control analysis shows the majority of autoimmune diseases demonstrate no effect on the development of new-onset age-related macular degeneration.

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Frontiers in Cardiovascular Medicine

JANUARY 3, 2024

Introduction A new technology capable of monitoring local impedance (LI) and contact force (CF) has recently been developed. At the same time, there is growing concern regarding catheter ablation performed under fluoroscopy guidance, due to its harmful effects for both patients and practitioners. The aim of this study was to assess the safety and effectiveness of zero-fluoroscopy cavotricuspid isthmus (CTI) ablation monitoring LI drop and CF as well as to elucidate if these parameters can predic

Ablation 89

Ablation Technology 89

Dr. Smith's ECG Blog

JANUARY 3, 2024

Written by Pendell Meyers A woman in her 70s had acute chest pain and called EMS. On arrival, EMS recorded relatively normal vital signs and this EMS ECG: What do you think? Interpretation : diagnostic of acute anterior OMI with STE less than STEMI criteria in V1-V4, hyperacute T waves in V2-V4, and suspiciously flat isoelectric ST segments in III and aVF suspicious for reciprocal findings.

STEMI 86

STEMI Chest Pain Ischemia Outcomes 86

Frontiers in Cardiovascular Medicine

JANUARY 3, 2024

Hypertrophic cardiomyopathy is the most common genetic cardiac disorder and is defined by the presence of left ventricular (LV) hypertrophy in the absence of a condition capable of producing such a magnitude of hypertrophy. Over the past decade, guidelines on the screening, diagnostic, and management protocols of pediatric primary (i.e., sarcomeric) HCM have undergone significant revisions.

Pediatrics 87

Pediatrics Cardiomyopathy Heart Failure Exercise 87

The New England Journal of Medicine

JANUARY 3, 2024

In a trial involving patients with infrapopliteal artery disease, the use of a drug-eluting resorbable scaffold was superior to angioplasty in reducing reintervention and maintaining patency at 1 year.

Angioplasty 75

Angioplasty 75

Frontiers in Cardiovascular Medicine

JANUARY 3, 2024

The autonomic nervous system plays a crucial role in atrial fibrillation pathophysiology. Parasympathetic hyperactivity result in a shortening of the action potential duration, a reduction of the conduction wavelength, and as such facilitates reentry in the presence of triggers. Further, autonomic remodeling of atrial myocytes in AF includes progressive sympathetic hyperinnervation by increased atrial sympathetic nerve density and sympathetic atrial nerve sprouting.

Atrial Fibrillation 80

Atrial Fibrillation 80

HCPLive

JANUARY 3, 2024

The biosimilars month in review highlights interviews with experts discussing the cost-saving potential of increased biosimilars uptake in the US, a recent US Food and Drug Administration (FDA) approval, and the impact of a mandatory switch to an adalimumab biosimilar in New Zealand.

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Frontiers in Cardiovascular Medicine

JANUARY 3, 2024

Hypertension constitutes a pervasive chronic ailment on a global scale, frequently inflicting damage upon vital organs, such as the heart, blood vessels, kidneys, brain, and others. And this is a complex clinical dilemma that requires immediate attention. The mitochondria assume a crucial function in the generation of energy, and it is of utmost importance to eliminate any malfunctioning or surplus mitochondria to uphold intracellular homeostasis.

Hypertension 72

Hypertension Physiology Innovation Article 72

American College of Cardiology

JANUARY 3, 2024

The goal of the REVIVED-BCIS2 trial was to evaluate percutaneous coronary intervention (PCI) plus optimal medical therapy compared with optimal medical therapy alone among individuals with left ventricular ejection fraction (LVEF) ≤35% and extensive coronary artery disease (CAD).

Coronary Artery Disease 72

Coronary Artery Disease Article 72

Frontiers in Cardiovascular Medicine

JANUARY 3, 2024

Introduction Coronary artery bypass grafting (CABG) is the most common cardiac surgical procedure. The prognosis of revascularization via CABG is determined by the patency of the used grafts, for which an intact endothelium is essential. The degree of ischemia-reperfusion injury (IRI), which occurs during the harvest and implantation of the grafts, is an important determinant of graft patency.

Coronary Artery Bypass Graft 64

Coronary Artery Bypass Graft Transplant Ischemia Aortic 64

CardiacWire

JANUARY 3, 2024

Topline results from Cytokinetics’ SEQUOIA-HCM phase 3 trial suggest that 2024 could be the company’s best year ever, showing that its investigative obstructive hypertrophic cardiomyopathy (HCM) drug aficamten significantly improved all primary and secondary endpoints. HCM causes the heart muscle to become abnormally thick, limiting the heart’s pumping function and leading to reduced exercise capacity, a range of other symptoms, and greater risks of severe CV complications.

Exercise 64

Exercise Cardiomyopathy Heart Failure 64

Frontiers in Cardiovascular Medicine

JANUARY 3, 2024

Background Multiple clinical studies have found a significant correlation between elevated galectin-3 (Gal-3) in circulation and the diagnosis and severity of peripheral arterial disease (PAD). The current study used the Mendelian randomization (MR) technique to evaluate the possible causal relationship between Gal-3 and PAD. Methods Genome-wide association study (GWAS) data of Gal-3 and PAD were obtained through the MR-Base platform.

Peripheral Arterial Disease 64

Peripheral Arterial Disease Circulation Outcomes 64

Physiologically Speaking

JANUARY 3, 2024

Cardiovascular physiology has long held that the heart is a mechanical pump and that the heart’s propulsive power is the main driver of blood flow throughout the body. However, the cardiocentric view of circulation fails to explain blood flow regulation during exercise and other unique scenarios. Thus, a new model is proposed in which metabolic demands at the tissue level are the primary driver of circulation — the heart plays a permissive role.

Physiology 64

Physiology Circulation Pulmonary Exercise 64

HCPLive

JANUARY 3, 2024

Efficacy, pharmacokinetics, immunogenicity, and safety were comparable between patients receiving the aflibercept biosimilar SB15 and the reference drug.

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NEJM Journal Watch - Cardiology

JANUARY 3, 2024

NEJM Journal Watch reviews over 250 scientific and medical journals to present important clinical research findings and insightful commentary

Research 81

Research 81

HCPLive

JANUARY 3, 2024

Our December 2023 Gastroenterology Month in Review features a pair of American Gastroenterological Association guidelines and articles from the fourth installment of Qazi Corner.

Article 59

Article 59

Frontiers in Cardiovascular Medicine

JANUARY 3, 2024

Background Microcirculatory dysfunction is an independent risk factor for a poor prognosis after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI). Trichosanthes pericarpium is a well-known Chinese traditional herb described with the effect of activating blood circulation to dissipate blood stasis and improve blood circulation.

Myocardial Infarction 59

Myocardial Infarction Outcomes Cardiac Function Thrombolysis 59

HCPLive

JANUARY 3, 2024

Each month, our editorial staff compiles a recap of the top news in ophthalmology. Our December 2023 month-in-review features a recap of This Year in Medicine, the latest updates to the ophthalmic pipeline, and the newest episode of our KOL-led podcast series.

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DAIC

JANUARY 3, 2024

milla1cf Wed, 01/03/2024 - 11:45 January 3, 2024 — HeartFlow, Inc. , a leader in non-invasive artificial intelligence (AI) precision coronary care solutions, today announced that it has surpassed 250,000 patients receiving a HeartFlow FFR CT Analysis. This accomplishment is a testament to HeartFlow's dedication to driving a new standard of care and marks an important milestone for the company.

Coronary Artery Disease 59

Coronary Artery Disease Chest Pain Plaque Technology 59

HCPLive

JANUARY 3, 2024

Our cardiology month in review spotlights our most popular cardiology-centric content from the month of December 2023. The list includes topline data from SEQUOIA-HCM, new data on the impact of structural racism on chronic health conditions, and more!

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DAIC

JANUARY 3, 2024

milla1cf Wed, 01/03/2024 - 11:59 January 3, 2024 — Cardionomic, Inc. , a Minneapolis medical device company, is pleased to announce the completion of enrollment in both their STIM-ADHF and STOP-ADHF pilot studies. Both studies were designed to evaluate the safety and performance of the Cardiac Pulmonary Nerve Stimulation (CPNS) System in patients suffering from Acute Decompensated Heart Failure (ADHF), defined as new or worsening symptoms of heart failure.

Heart Failure 59

Heart Failure Pulmonary Inpatient Hospital 59

HCPLive

JANUARY 3, 2024

These study results highlight the necessity of raising awareness and implementing public health interventions designed to address respiratory health among this and other populations in early childhood.

Public Health 59

Public Health 59

European Journal of Heart Failure

JANUARY 3, 2024

Abstract Document Reviewers: Rudolf A. de Boer (CPG Review Co-ordinator) (Netherlands), P. Christian Schulze (CPG Review Co-ordinator) (Germany), Elena Arbelo (Spain), Jozef Bartunek (Belgium), Johann Bauersachs (Germany), Michael A. Borger (Germany), Sergio Buccheri (Sweden), Elisabetta Cerbai (Italy), Erwan Donal (France), Frank Edelmann (Germany), Gloria Färber (Germany), Bettina Heidecker (Germany), Borja Ibanez (Spain), Stefan James (Sweden), Lars Køber (Denmark), Konstantinos C.

Heart Failure 65

Heart Failure Document 65

HCPLive

JANUARY 3, 2024

IVF treatment and pregnancy outcomes were not significantly different between patients with and without liver disease who received assisted reproductive technology treatment.

Technology 59

Technology Outcomes 59

NEJM Journal Watch - Cardiology

JANUARY 3, 2024

NEJM Journal Watch reviews over 250 scientific and medical journals to present important clinical research findings and insightful commentary

ACE Inhibitor 75

ACE Inhibitor Research 75

American College of Cardiology

JANUARY 3, 2024

The following are key points to remember from the American Heart Association (AHA) Scientific Statement on cardiovascular implantable electronic device (CIED) infections and their prevention, diagnosis, and management.

Article 62

Article 62

HCPLive

JANUARY 3, 2024

A systematic review combined with a pair of case studies suggest men who discontinue the front-line treatment for conditions like polycythaemia vera may improve their fertility.

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DAIC

JANUARY 3, 2024

Artificial Intelligence (AI)-driven Primary Care company K Health has announced it has entered into a know-how agreement with Mayo Clinic on the development of a cardiac clinical AI solution with the intent to prevent premature deaths from heart disease and stroke. Image courtesy: K Health christine.book Wed, 01/03/2024 - 22:16 January 4, 2024 — Artificial Intelligence (AI)-driven Primary Care company K Health has announced it has entered into a know-how agreement with Mayo Clinic to tackle th

Heart Disease 52

Heart Disease Technology Patient Care Hypertension 52